IT8167438A0 - Inibitori della biosintesi del colesterolo loro preparazione ed impiego - Google Patents

Inibitori della biosintesi del colesterolo loro preparazione ed impiego

Info

Publication number
IT8167438A0
IT8167438A0 IT8167438A IT6743881A IT8167438A0 IT 8167438 A0 IT8167438 A0 IT 8167438A0 IT 8167438 A IT8167438 A IT 8167438A IT 6743881 A IT6743881 A IT 6743881A IT 8167438 A0 IT8167438 A0 IT 8167438A0
Authority
IT
Italy
Prior art keywords
preparation
biosynthesis inhibitors
cholesterol biosynthesis
cholesterol
inhibitors
Prior art date
Application number
IT8167438A
Other languages
English (en)
Other versions
IT1144325B (it
Inventor
Aiya Sato Akira Terahara
Yoshio Tsujita
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12604367&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT8167438(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of IT8167438A0 publication Critical patent/IT8167438A0/it
Application granted granted Critical
Publication of IT1144325B publication Critical patent/IT1144325B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT67438/81A 1980-03-31 1981-03-30 Inibitori della biosintesi del colesterolo loro preparazione ed impiego IT1144325B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55041292A JPH0692381B2 (ja) 1980-03-31 1980-03-31 Ｍｂ−５３０ａ誘導体

Publications (2)

Publication Number Publication Date
IT8167438A0 true IT8167438A0 (it) 1981-03-30
IT1144325B IT1144325B (it) 1986-10-29

Family

ID=12604367

Family Applications (1)

Application Number Title Priority Date Filing Date
IT67438/81A IT1144325B (it) 1980-03-31 1981-03-30 Inibitori della biosintesi del colesterolo loro preparazione ed impiego

Country Status (15)

Country Link
JP (1) JPH0692381B2 (it)
AT (1) ATA150781A (it)
AU (1) AU6893281A (it)
BE (1) BE888214A (it)
CH (1) CH646966A5 (it)
DE (2) DE3153666C2 (it)
DK (3) DK151273C (it)
FI (1) FI810991L (it)
FR (1) FR2479222A1 (it)
GB (1) GB2073193A (it)
IE (1) IE52367B1 (it)
IT (1) IT1144325B (it)
MX (1) MX9203567A (it)
NL (1) NL8101592A (it)
SE (1) SE461590B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472426A (en) * 1982-12-22 1984-09-18 Merck & Co., Inc. Antihypercholesterolemic compounds
EP0215665B1 (en) * 1985-09-13 1991-11-21 Sankyo Company Limited Hydroxy-ml-236b derivatives, their preparation and use
US4997848A (en) * 1987-10-27 1991-03-05 Sankyo Company, Limited Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
US5075327A (en) * 1988-08-10 1991-12-24 Hoffmann-La Roche Inc. Antipsoriatic agents
US5073568A (en) * 1988-11-14 1991-12-17 Hoffmann-La Roche Inc. Antipsoriatic agents
US5021451A (en) * 1988-11-14 1991-06-04 Hoffman-La Roche Inc. Method for inhibiting hyperproliferative diseases
US5200549A (en) * 1988-11-14 1993-04-06 Hoffman-La Roche Inc. Antipsoriatic agents
US5159104A (en) * 1991-05-01 1992-10-27 Merck & Co., Inc. Process to simvastatin ester
FR2937537A1 (fr) * 2008-10-29 2010-04-30 Centre Nat Rech Scient Nanoparticules de statine
KR101820099B1 (ko) 2013-01-18 2018-01-18 에스프린팅솔루션 주식회사 저항 발열체, 이를 채용한 가열 부재, 및 정착 장치
CA3087932A1 (en) * 2018-01-09 2019-07-18 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612114B2 (it) * 1974-06-07 1981-03-18
JPS5925599B2 (ja) * 1979-02-20 1984-06-19 三共株式会社 新生理活性物質モナコリンｋおよびその製造法
AU535944B2 (en) * 1979-06-15 1984-04-12 Merck & Co., Inc. Hypocholestermic fermentation products from aspergillus
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
ZA81703B (en) * 1980-02-04 1982-09-29 Merck & Co Inc New antihypercholesterolemic compounds,intermediates and processes
PT72394B (en) * 1980-02-04 1982-09-06 Merck & Co Inc Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics
AU548996B2 (en) * 1980-02-04 1986-01-09 Merck & Co., Inc. Tetrahydro-2h-pyran-2-one derivatives
US4282155A (en) * 1980-02-04 1981-08-04 Merck & Co., Inc. Antihypercholesterolemic compounds

Also Published As

Publication number Publication date
ATA150781A (de) 1983-03-15
IT1144325B (it) 1986-10-29
DE3153666C2 (de) 1993-11-11
DK151273C (da) 1988-07-04
FI810991A7 (fi) 1981-10-01
FR2479222A1 (fr) 1981-10-02
FI810991L (fi) 1981-10-01
FR2479222B1 (it) 1983-08-26
DK32290D0 (da) 1990-02-07
IE52367B1 (en) 1987-09-30
DE3112566C2 (it) 1990-04-05
NL8101592A (nl) 1981-10-16
IE810698L (en) 1981-09-30
DK32190A (da) 1990-02-07
DK32190D0 (da) 1990-02-07
CH646966A5 (de) 1984-12-28
SE461590B (sv) 1990-03-05
BE888214A (fr) 1981-09-30
DK145481A (da) 1981-10-01
JPH0692381B2 (ja) 1994-11-16
DK167805B1 (da) 1993-12-20
GB2073193A (en) 1981-10-14
AU6893281A (en) 1981-10-08
SE8102047L (sv) 1981-10-01
MX9203567A (es) 1992-09-01
DK151273B (da) 1987-11-16
JPS56138181A (en) 1981-10-28
DE3112566A1 (de) 1982-03-11
DK32290A (da) 1990-02-07

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970329