SE459090B - N-metyl-d-glukaminsalt av (+)-2-(2-fluor-4-bifenylyl)-propionsyra, farmaceutiska kompositioner innefattande det samt foerfarande foer framstaellning av saltet - Google Patents

N-metyl-d-glukaminsalt av (+)-2-(2-fluor-4-bifenylyl)-propionsyra, farmaceutiska kompositioner innefattande det samt foerfarande foer framstaellning av saltet

Info

Publication number
SE459090B
SE459090B SE8206984A SE8206984A SE459090B SE 459090 B SE459090 B SE 459090B SE 8206984 A SE8206984 A SE 8206984A SE 8206984 A SE8206984 A SE 8206984A SE 459090 B SE459090 B SE 459090B
Authority
SE
Sweden
Prior art keywords
salt
fluoro
propionic acid
methyl
biphenylyl
Prior art date
Application number
SE8206984A
Other languages
English (en)
Swedish (sv)
Other versions
SE8206984L (sv
SE8206984D0 (sv
Inventor
B J Armitage
M L Donaldson
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of SE8206984D0 publication Critical patent/SE8206984D0/xx
Publication of SE8206984L publication Critical patent/SE8206984L/
Publication of SE459090B publication Critical patent/SE459090B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SE8206984A 1981-12-08 1982-12-07 N-metyl-d-glukaminsalt av (+)-2-(2-fluor-4-bifenylyl)-propionsyra, farmaceutiska kompositioner innefattande det samt foerfarande foer framstaellning av saltet SE459090B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8136989 1981-12-08

Publications (3)

Publication Number Publication Date
SE8206984D0 SE8206984D0 (sv) 1982-12-07
SE8206984L SE8206984L (sv) 1983-06-09
SE459090B true SE459090B (sv) 1989-06-05

Family

ID=10526449

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8206984A SE459090B (sv) 1981-12-08 1982-12-07 N-metyl-d-glukaminsalt av (+)-2-(2-fluor-4-bifenylyl)-propionsyra, farmaceutiska kompositioner innefattande det samt foerfarande foer framstaellning av saltet

Country Status (23)

Country Link
US (1) US4501727A (da)
JP (1) JPS58113144A (da)
AT (1) AT391688B (da)
AU (1) AU555937B2 (da)
BE (1) BE895269A (da)
CA (1) CA1202329A (da)
CH (1) CH654288A5 (da)
DE (1) DE3245469A1 (da)
DK (1) DK541782A (da)
ES (1) ES8604480A1 (da)
FI (1) FI73964C (da)
FR (1) FR2517670B1 (da)
GB (1) GB2111493B (da)
GR (1) GR77840B (da)
IE (1) IE54266B1 (da)
IT (1) IT1196426B (da)
LU (1) LU84512A1 (da)
NL (1) NL8204471A (da)
NO (1) NO156165C (da)
NZ (1) NZ202672A (da)
PT (1) PT75889B (da)
SE (1) SE459090B (da)
ZA (1) ZA828453B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
US4883818A (en) * 1987-11-17 1989-11-28 Analgesic Associates Onset-hastened/enhanced analgesia
US4927854A (en) * 1987-12-24 1990-05-22 Analgesic Associates Sustained/enhanced analgesia
US5286751A (en) * 1987-12-24 1994-02-15 Analgesic Associates Sustained/enhanced antipyretic response
DE4028906A1 (de) † 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
HUT59692A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alkanoic acids and aminosugars
US5621140A (en) * 1994-12-22 1997-04-15 Syntex (U.S.A.) Inc. Resolution of ibuprofen
IN189741B (da) * 1998-11-09 2003-04-19 Council Scient Ind Res
AU2001292929A1 (en) 2000-09-26 2002-04-08 Temple University Of The Commonwealth System Of Higher Education Analgesic and glucosamine compositions
ITMI20040235A1 (it) * 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale
CA2605863C (en) * 2005-04-29 2016-07-05 University Of Louisville Research Foundation, Inc. Cell-surface decoration with active agents
US20070237816A1 (en) * 2006-04-06 2007-10-11 David Finkelstein Acetaminophen formulation for joint pain relief

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1091403A (en) * 1964-01-24 1967-11-15 Boots Pure Drug Co Ltd Therapeutically active phenylalkane derivatives
ES383442A1 (es) * 1970-09-07 1973-01-01 Gallardo Antonio Sa Procedimiento para la obtencion de una nueva sal de n-me- tilglucamina con el acido 6-d-(-)-alfa-amino fenil-acetamido-penicilanico.
GB1359987A (en) * 1970-10-12 1974-07-17 Boots Co Ltd 2-substituted biphenylyl propionic acids
DE2158071A1 (de) * 1971-04-21 1972-10-26 Farmaceutici Chiesi S n c , Parma (Italien) Therapeutisch wirksames Salz des Indomethacine
US3860624A (en) * 1971-07-21 1975-01-14 Rorer Inc William H P-cyclohexyl alpha - lower alkanoylthio hydrocinamic acid
US3903134A (en) * 1971-07-21 1975-09-02 Rorer Inc William H Phenyl propionic acids and derivatives thereof
US3985788A (en) * 1971-07-21 1976-10-12 William H. Rorer, Inc. Phenyl propionic acids and derivatives thereof
US3987197A (en) * 1972-08-17 1976-10-19 Boehringer Ingelheim Gmbh 3-(2'-fluoro-4-biphenylyl)-butyric acid and salts thereof
US3891761A (en) * 1973-03-28 1975-06-24 Schering Corp N-Methyl-d-glucamine salt of 2(2-methyl-3{40 -trifluoro-methylanilino) nicotinic acid in the treatment of pain
US4209638A (en) * 1977-03-08 1980-06-24 The Boots Company Limited Preparation of therapeutic agents
FR2413353A1 (fr) * 1977-12-27 1979-07-27 Fabre Sa Pierre L'acetyl salicylate de n-methyl glucamine, nouveau derive hydrosoluble
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.
PH15674A (en) * 1979-07-06 1983-03-11 Syntex Corp Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid
LU83138A1 (de) * 1981-02-16 1981-09-11 T Eckert Topische pharmazeutische praeparate,enthaltend salze von alkancarbonsaeuren sowie neue carbonsaeuresalze und verfahren zu ihrer herstellung
BE887671A (fr) * 1981-02-25 1981-08-25 Eckert Theod P Preparations pharmaceutiques topiques contenant des sels d'acides alcane-carboxyliques ainsi que de nouveaux sels d'acides carboxyliques et leurs procedes de preparation

Also Published As

Publication number Publication date
AT391688B (de) 1990-11-12
JPH047337B2 (da) 1992-02-10
AU9084582A (en) 1983-06-16
IT8224624A0 (it) 1982-12-06
PT75889B (en) 1985-11-15
IT1196426B (it) 1988-11-16
CA1202329A (en) 1986-03-25
NO156165B (no) 1987-04-27
SE8206984L (sv) 1983-06-09
DE3245469C2 (da) 1991-11-07
NZ202672A (en) 1984-09-28
IE822766L (en) 1983-06-08
ES517984A0 (es) 1986-02-01
FR2517670B1 (fr) 1986-06-20
FI73964C (fi) 1987-12-10
FI73964B (fi) 1987-08-31
NL8204471A (nl) 1983-07-01
IE54266B1 (en) 1989-08-02
BE895269A (fr) 1983-06-07
FR2517670A1 (fr) 1983-06-10
JPS58113144A (ja) 1983-07-05
ATA443282A (de) 1990-05-15
US4501727A (en) 1985-02-26
FI824098L (fi) 1983-06-09
ZA828453B (en) 1983-12-28
CH654288A5 (fr) 1986-02-14
DE3245469A1 (de) 1983-07-21
SE8206984D0 (sv) 1982-12-07
LU84512A1 (fr) 1984-03-07
FI824098A0 (fi) 1982-11-29
AU555937B2 (en) 1986-10-16
IT8224624A1 (it) 1984-06-06
GB2111493B (en) 1985-06-12
GB2111493A (en) 1983-07-06
NO156165C (no) 1987-08-05
ES8604480A1 (es) 1986-02-01
DK541782A (da) 1983-06-09
NO824112L (no) 1983-06-09
PT75889A (en) 1982-12-01
GR77840B (da) 1984-09-25

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