ATA443282A - Verfahren zur herstellung des neuen n-methyl-dglucamin-salzes von (+)-2-(2-fluor-4-biphenylyl)- propionsaeure - Google Patents

Verfahren zur herstellung des neuen n-methyl-dglucamin-salzes von (+)-2-(2-fluor-4-biphenylyl)- propionsaeure

Info

Publication number
ATA443282A
ATA443282A AT0443282A AT443282A ATA443282A AT A443282 A ATA443282 A AT A443282A AT 0443282 A AT0443282 A AT 0443282A AT 443282 A AT443282 A AT 443282A AT A443282 A ATA443282 A AT A443282A
Authority
AT
Austria
Prior art keywords
biphenylyl
fluor
methyl
producing
new
Prior art date
Application number
AT0443282A
Other languages
English (en)
Other versions
AT391688B (de
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of ATA443282A publication Critical patent/ATA443282A/de
Application granted granted Critical
Publication of AT391688B publication Critical patent/AT391688B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT0443282A 1981-12-08 1982-12-06 Verfahren zur herstellung des neuen n-methyl-dglucamin-salzes von (+)-2-(2-fluor-4-biphenylyl)- propionsaeure AT391688B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8136989 1981-12-08

Publications (2)

Publication Number Publication Date
ATA443282A true ATA443282A (de) 1990-05-15
AT391688B AT391688B (de) 1990-11-12

Family

ID=10526449

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0443282A AT391688B (de) 1981-12-08 1982-12-06 Verfahren zur herstellung des neuen n-methyl-dglucamin-salzes von (+)-2-(2-fluor-4-biphenylyl)- propionsaeure

Country Status (23)

Country Link
US (1) US4501727A (de)
JP (1) JPS58113144A (de)
AT (1) AT391688B (de)
AU (1) AU555937B2 (de)
BE (1) BE895269A (de)
CA (1) CA1202329A (de)
CH (1) CH654288A5 (de)
DE (1) DE3245469A1 (de)
DK (1) DK541782A (de)
ES (1) ES8604480A1 (de)
FI (1) FI73964C (de)
FR (1) FR2517670B1 (de)
GB (1) GB2111493B (de)
GR (1) GR77840B (de)
IE (1) IE54266B1 (de)
IT (1) IT1196426B (de)
LU (1) LU84512A1 (de)
NL (1) NL8204471A (de)
NO (1) NO156165C (de)
NZ (1) NZ202672A (de)
PT (1) PT75889B (de)
SE (1) SE459090B (de)
ZA (1) ZA828453B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
US4883818A (en) * 1987-11-17 1989-11-28 Analgesic Associates Onset-hastened/enhanced analgesia
US4927854A (en) * 1987-12-24 1990-05-22 Analgesic Associates Sustained/enhanced analgesia
US5286751A (en) * 1987-12-24 1994-02-15 Analgesic Associates Sustained/enhanced antipyretic response
DE4028906A1 (de) † 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
HUT59692A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alkanoic acids and aminosugars
US5621140A (en) * 1994-12-22 1997-04-15 Syntex (U.S.A.) Inc. Resolution of ibuprofen
IN189741B (de) * 1998-11-09 2003-04-19 Council Scient Ind Res
EP1328278A4 (de) 2000-09-26 2004-06-16 Univ Temple Analgetische und glucosamin-zusammensetzungen
ITMI20040235A1 (it) * 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale
CA2605863C (en) * 2005-04-29 2016-07-05 University Of Louisville Research Foundation, Inc. Cell-surface decoration with active agents
US20070237816A1 (en) * 2006-04-06 2007-10-11 David Finkelstein Acetaminophen formulation for joint pain relief

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1091403A (en) * 1964-01-24 1967-11-15 Boots Pure Drug Co Ltd Therapeutically active phenylalkane derivatives
ES383442A1 (es) * 1970-09-07 1973-01-01 Gallardo Antonio Sa Procedimiento para la obtencion de una nueva sal de n-me- tilglucamina con el acido 6-d-(-)-alfa-amino fenil-acetamido-penicilanico.
GB1359987A (en) * 1970-10-12 1974-07-17 Boots Co Ltd 2-substituted biphenylyl propionic acids
DE2158071A1 (de) * 1971-04-21 1972-10-26 Farmaceutici Chiesi S n c , Parma (Italien) Therapeutisch wirksames Salz des Indomethacine
US3903134A (en) * 1971-07-21 1975-09-02 Rorer Inc William H Phenyl propionic acids and derivatives thereof
US3860624A (en) * 1971-07-21 1975-01-14 Rorer Inc William H P-cyclohexyl alpha - lower alkanoylthio hydrocinamic acid
US3985788A (en) * 1971-07-21 1976-10-12 William H. Rorer, Inc. Phenyl propionic acids and derivatives thereof
US3987197A (en) * 1972-08-17 1976-10-19 Boehringer Ingelheim Gmbh 3-(2'-fluoro-4-biphenylyl)-butyric acid and salts thereof
US3891761A (en) * 1973-03-28 1975-06-24 Schering Corp N-Methyl-d-glucamine salt of 2(2-methyl-3{40 -trifluoro-methylanilino) nicotinic acid in the treatment of pain
US4209638A (en) * 1977-03-08 1980-06-24 The Boots Company Limited Preparation of therapeutic agents
FR2413353A1 (fr) * 1977-12-27 1979-07-27 Fabre Sa Pierre L'acetyl salicylate de n-methyl glucamine, nouveau derive hydrosoluble
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.
PH15674A (en) * 1979-07-06 1983-03-11 Syntex Corp Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid
LU83138A1 (de) * 1981-02-16 1981-09-11 T Eckert Topische pharmazeutische praeparate,enthaltend salze von alkancarbonsaeuren sowie neue carbonsaeuresalze und verfahren zu ihrer herstellung
BE887671A (fr) * 1981-02-25 1981-08-25 Eckert Theod P Preparations pharmaceutiques topiques contenant des sels d'acides alcane-carboxyliques ainsi que de nouveaux sels d'acides carboxyliques et leurs procedes de preparation

Also Published As

Publication number Publication date
FI73964B (fi) 1987-08-31
IE822766L (en) 1983-06-08
AU9084582A (en) 1983-06-16
DK541782A (da) 1983-06-09
DE3245469C2 (de) 1991-11-07
IT8224624A1 (it) 1984-06-06
IT8224624A0 (it) 1982-12-06
DE3245469A1 (de) 1983-07-21
JPH047337B2 (de) 1992-02-10
PT75889B (en) 1985-11-15
NO824112L (no) 1983-06-09
CA1202329A (en) 1986-03-25
SE8206984D0 (sv) 1982-12-07
IE54266B1 (en) 1989-08-02
GB2111493A (en) 1983-07-06
AU555937B2 (en) 1986-10-16
FI824098L (fi) 1983-06-09
GR77840B (de) 1984-09-25
AT391688B (de) 1990-11-12
SE459090B (sv) 1989-06-05
NO156165B (no) 1987-04-27
PT75889A (en) 1982-12-01
NL8204471A (nl) 1983-07-01
ES517984A0 (es) 1986-02-01
IT1196426B (it) 1988-11-16
NZ202672A (en) 1984-09-28
SE8206984L (sv) 1983-06-09
CH654288A5 (fr) 1986-02-14
NO156165C (no) 1987-08-05
US4501727A (en) 1985-02-26
LU84512A1 (fr) 1984-03-07
ES8604480A1 (es) 1986-02-01
FR2517670A1 (fr) 1983-06-10
FI824098A0 (fi) 1982-11-29
FR2517670B1 (fr) 1986-06-20
BE895269A (fr) 1983-06-07
ZA828453B (en) 1983-12-28
JPS58113144A (ja) 1983-07-05
GB2111493B (en) 1985-06-12
FI73964C (fi) 1987-12-10

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Legal Events

Date Code Title Description
EIH Change in the person of patent owner
ELJ Ceased due to non-payment of the annual fee