SE447574B - Inklusionskomplex av prostacyklin-metylester och beta-cyklodextrin, sett for dess framstellning samt lekemedelsberedning baserad derpa - Google Patents

Inklusionskomplex av prostacyklin-metylester och beta-cyklodextrin, sett for dess framstellning samt lekemedelsberedning baserad derpa

Info

Publication number
SE447574B
SE447574B SE7809946A SE7809946A SE447574B SE 447574 B SE447574 B SE 447574B SE 7809946 A SE7809946 A SE 7809946A SE 7809946 A SE7809946 A SE 7809946A SE 447574 B SE447574 B SE 447574B
Authority
SE
Sweden
Prior art keywords
prostacyclin
cyclodextrin
methyl ester
inclusion complex
solution
Prior art date
Application number
SE7809946A
Other languages
English (en)
Swedish (sv)
Other versions
SE7809946L (sv
Inventor
J Szejtli
M Szejtli
G Cseh
I Stadler
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of SE7809946L publication Critical patent/SE7809946L/xx
Publication of SE447574B publication Critical patent/SE447574B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nanotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
SE7809946A 1977-09-23 1978-09-21 Inklusionskomplex av prostacyklin-metylester och beta-cyklodextrin, sett for dess framstellning samt lekemedelsberedning baserad derpa SE447574B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77CI1770A HU179141B (fi) 1977-09-23 1977-09-23

Publications (2)

Publication Number Publication Date
SE7809946L SE7809946L (sv) 1979-03-24
SE447574B true SE447574B (sv) 1986-11-24

Family

ID=10994670

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7809946A SE447574B (sv) 1977-09-23 1978-09-21 Inklusionskomplex av prostacyklin-metylester och beta-cyklodextrin, sett for dess framstellning samt lekemedelsberedning baserad derpa

Country Status (20)

Country Link
JP (1) JPS5456685A (fi)
AT (1) AT369362B (fi)
BE (1) BE870646A (fi)
CH (1) CH637388A5 (fi)
CS (1) CS200242B2 (fi)
DD (1) DD138600A5 (fi)
DE (1) DE2840142A1 (fi)
DK (1) DK420778A (fi)
FI (1) FI65912C (fi)
FR (1) FR2404006A1 (fi)
GB (1) GB2006193B (fi)
GR (1) GR65001B (fi)
HU (1) HU179141B (fi)
IL (1) IL55569A (fi)
IT (1) IT1160661B (fi)
NL (1) NL7809643A (fi)
PL (1) PL121664B1 (fi)
SE (1) SE447574B (fi)
SU (1) SU847914A3 (fi)
YU (1) YU220678A (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
US4352793A (en) * 1979-04-26 1982-10-05 Sumitomo Chemical Company, Limited Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
JPS61289034A (ja) * 1985-06-17 1986-12-19 Teijin Ltd イソカルバサイクリン類脂肪乳剤
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
DE3740838A1 (de) * 1987-11-27 1989-06-08 Schering Ag Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel
JPWO2005073223A1 (ja) * 2004-01-29 2007-09-13 エーザイ・アール・アンド・ディー・マネジメント株式会社 マクロライド系化合物の安定化方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (fi) * 1970-06-10 1975-02-04
US3953435A (en) * 1974-01-10 1976-04-27 Ono Pharmaceutical Company Aldehyde derivatives of prostaglandins
JPS5395958A (en) * 1977-01-31 1978-08-22 Ono Pharmaceut Co Ltd Prostaglandin analogues and process for their preparation
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds

Also Published As

Publication number Publication date
SE7809946L (sv) 1979-03-24
PL209773A1 (pl) 1979-06-04
PL121664B1 (en) 1982-05-31
DE2840142A1 (de) 1979-04-05
IT7869160A0 (it) 1978-09-19
FI782878A (fi) 1979-03-24
FR2404006B1 (fi) 1981-07-31
AT369362B (de) 1982-12-27
JPS5456685A (en) 1979-05-07
HU179141B (fi) 1982-08-28
GB2006193A (en) 1979-05-02
SU847914A3 (ru) 1981-07-15
CS200242B2 (en) 1980-08-29
DD138600A5 (de) 1979-11-14
DK420778A (da) 1979-03-24
GR65001B (en) 1980-06-12
FI65912B (fi) 1984-04-30
BE870646A (fr) 1979-01-15
IT1160661B (it) 1987-03-11
NL7809643A (nl) 1979-03-27
YU220678A (en) 1983-10-31
IL55569A0 (en) 1978-12-17
FI65912C (fi) 1984-08-10
ATA677478A (de) 1982-05-15
GB2006193B (en) 1982-05-26
CH637388A5 (de) 1983-07-29
FR2404006A1 (fr) 1979-04-20
IL55569A (en) 1981-12-31

Similar Documents

Publication Publication Date Title
DE69213256T2 (de) Organische salze von n, n'-diacetylcystin
JPH01308231A (ja) 安定化された医薬組成物および製造法
BRPI0720277A2 (pt) Formulações e métodos de uso das mesmas
KR860009032A (ko) γ-사이클로 덱스트린 유도체의 제조방법
FI67390C (fi) Foerfarande foer framstaellning av en inklusionskomplex av n-(1-fenyletyl)-3,3-difenylpropylamin eller dess hydroklorid me cyklodextrin
SE447574B (sv) Inklusionskomplex av prostacyklin-metylester och beta-cyklodextrin, sett for dess framstellning samt lekemedelsberedning baserad derpa
CN114195851B (zh) 一种用于防治肝病的化合物及其药用组合物
EP0451869B1 (en) Use of steroid derivatives in the treatment of endometriosis
IE63156B1 (en) Dry substances and stable suspensions
CS214798B2 (en) Method of stabilization of active substances
US3900561A (en) Pharmaceutical compositions
EP0448029B1 (en) Novel pharmaceutical uses of forskolin derivatives
US4968673A (en) Use of a thromboxane receptor antagonist in renal diseases and dysfunction
DE60013583T2 (de) Verfahren zur herstellung von arzneimitteln eines basischen hydrophoben wirkstoffs
JPH07157431A (ja) 安定なプロスタグランジンe製剤
US2799617A (en) Piperazine adipate compositions and treatment of helminth infections therewith
PT100566B (pt) Azaspiranos imunomoduladores, composicoes farmaceuticas que os contem, sua preparacao e seu uso
IL21955A (en) Salts of fusidic acid and antibiotics of the tetracycline series
DE2735458A1 (de) Neue imidazolderivate
JPH0250086B2 (fi)
JP3061445B2 (ja) 血管拡張剤
US3810883A (en) Adenosine 3,5-cyclic monophosphate palmitates
US4113870A (en) Method for treatment of hypertension
US3821409A (en) Method of treatment
DE2632951A1 (de) Neue 1-deoxy-2,3-0-alkyliden-ribofuranuronsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7809946-2

Effective date: 19900703

Format of ref document f/p: F