SE440781B - Nya stereoidforeningar och anvendning derav sasom antiinflammatoriska medel - Google Patents

Nya stereoidforeningar och anvendning derav sasom antiinflammatoriska medel

Info

Publication number
SE440781B
SE440781B SE7904431A SE7904431A SE440781B SE 440781 B SE440781 B SE 440781B SE 7904431 A SE7904431 A SE 7904431A SE 7904431 A SE7904431 A SE 7904431A SE 440781 B SE440781 B SE 440781B
Authority
SE
Sweden
Prior art keywords
compounds
product
formula
solution
methyl
Prior art date
Application number
SE7904431A
Other languages
English (en)
Swedish (sv)
Other versions
SE7904431L (sv
Inventor
J G Teutsch
R Deraedt
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of SE7904431L publication Critical patent/SE7904431L/
Publication of SE440781B publication Critical patent/SE440781B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048—Alkynyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE7904431A 1978-07-13 1979-05-21 Nya stereoidforeningar och anvendning derav sasom antiinflammatoriska medel SE440781B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7820971A FR2430952A1 (fr) 1978-07-13 1978-07-13 Nouveaux derives acetyleniques de l'androst 4-ene, leur procede de preparation et leur application comme medicament

Publications (2)

Publication Number Publication Date
SE7904431L SE7904431L (sv) 1980-01-14
SE440781B true SE440781B (sv) 1985-08-19

Family

ID=9210731

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7904431A SE440781B (sv) 1978-07-13 1979-05-21 Nya stereoidforeningar och anvendning derav sasom antiinflammatoriska medel

Country Status (24)

Country Link
US (1) US4233297A (fr)
JP (2) JPS5515474A (fr)
AT (1) AT370109B (fr)
AU (1) AU534841B2 (fr)
BE (1) BE877658A (fr)
CA (1) CA1140110A (fr)
CH (2) CH641475A5 (fr)
DE (2) DE2928374A1 (fr)
DK (1) DK160560C (fr)
ES (1) ES482387A0 (fr)
FR (1) FR2430952A1 (fr)
GB (2) GB2025422B (fr)
GR (1) GR81403B (fr)
HU (1) HU180519B (fr)
IL (1) IL57533A (fr)
IT (1) IT1164697B (fr)
LU (1) LU81497A1 (fr)
MA (1) MA18516A1 (fr)
NL (1) NL7905481A (fr)
OA (1) OA06258A (fr)
PH (1) PH17055A (fr)
PT (1) PT69906A (fr)
SE (1) SE440781B (fr)
ZA (1) ZA793100B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2547587B1 (fr) * 1983-06-14 1985-10-25 Roussel Uclaf Steroides radioactifs, leur procede de preparation, leur application a la mise en evidence des recepteurs de glucocorticoides et au dosage du nombre de sites de fixation
FR2644788B1 (fr) * 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 3-ceto comportant une chaine en 17 amino-substituee, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
JPH02141007U (fr) * 1989-04-26 1990-11-27
DE69032648T2 (de) * 1989-07-07 1999-04-08 Endorecherche Inc Androgenderivate zur Hemming der Aktivität der Sexualsteroide
AU680818B2 (en) * 1992-05-21 1997-08-14 Endorecherche Inc. Improved antiandrogens
RU2141966C1 (ru) * 1993-05-17 1999-11-27 Андорешерш Инк. Антиандрогенные соединения, предшественник антиандрогенного соединения, фармацевтические композиции
CN103145785B (zh) * 2013-03-19 2016-03-02 浙江仙居仙乐药业有限公司 一种醋酸环丙孕酮脱氢物的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2740798A (en) * 1953-05-25 1956-04-03 Searle & Co 11 beta-hydroxy-17-ethynyl testosterone and esters thereof
US3010957A (en) * 1958-11-26 1961-11-28 Schering Corp Ethinyl androstadienes
FR1349113A (fr) * 1959-01-28 1964-01-17 Upjohn Co Procédé de fabrication de 6-fluoro-11 oxygéné-17-bêta-hydroxy-17 alpha-alkynyl inférieur-4-androstène-3-ones et leurs dérivés acylés
US3793308A (en) * 1972-11-08 1974-02-19 Upjohn Co 4-spiro(cyclopropyl)androstenes and process for their production
SE7801152L (sv) * 1977-02-22 1978-08-23 Roussel Uclaf Sett att framstella 17alfa-acetylen-derivat av androst-4-en

Also Published As

Publication number Publication date
DK160560C (da) 1991-09-09
IL57533A (en) 1984-01-31
ES8101081A1 (es) 1980-12-01
LU81497A1 (fr) 1980-02-14
JPS5515474A (en) 1980-02-02
AU4889479A (en) 1980-01-17
CA1140110A (fr) 1983-01-25
IT1164697B (it) 1987-04-15
CH642977A5 (fr) 1984-05-15
GB2108503A (en) 1983-05-18
JPS6362515B2 (fr) 1988-12-02
DE2954699C2 (fr) 1992-04-16
DK160560B (da) 1991-03-25
SE7904431L (sv) 1980-01-14
GB2108503B (en) 1983-09-14
FR2430952B1 (fr) 1980-12-05
NL7905481A (nl) 1980-01-15
AT370109B (de) 1983-03-10
PT69906A (fr) 1979-08-01
CH641475A5 (fr) 1984-02-29
JPS6252758B2 (fr) 1987-11-06
ES482387A0 (es) 1980-12-01
US4233297A (en) 1980-11-11
OA06258A (fr) 1981-06-30
BE877658A (fr) 1980-01-14
GB2025422B (en) 1983-05-05
DK292679A (da) 1980-01-14
GR81403B (fr) 1984-12-11
DE2928374C2 (fr) 1991-12-12
ZA793100B (en) 1980-06-25
AU534841B2 (en) 1984-02-16
GB2025422A (en) 1980-01-23
DE2928374A1 (de) 1980-01-31
HU180519B (en) 1983-03-28
JPS6345295A (ja) 1988-02-26
IL57533A0 (en) 1979-10-31
FR2430952A1 (fr) 1980-02-08
IT7949743A0 (it) 1979-07-12
ATA488979A (de) 1982-07-15
PH17055A (en) 1984-05-17
MA18516A1 (fr) 1980-04-01

Similar Documents

Publication Publication Date Title
DK169077B1 (da) Steroider, som i 10-stillingen er substitueret med aryl, aralkyl, arylthio, alkenyl eller alkynyl og farmaceutisk præparat indeholdende forbindelserne
CA1289944C (fr) LES 11.beta.-(4-ISOPROPENYLPHENYL)ESTRA-4,9-DIENES, LEUR PRODUCTION ET PREPARATIONS PHARMACEUTIQUES EN CONTENANT
EP0404283B1 (fr) 11-Bêta-aryl-4-estrène, son procédé de préparation et son application comme médicament
EP0280618B1 (fr) Nouveaux 19-nor stéroîdes substitués en position 7, leur préparation, leur application comme médicaments, les compositions pharmaceutiques les renfermant
EP0277089A1 (fr) 11-Bêta-alcynyl-estrènes et estradiènes, leur préparation et les compositions pharmaceutiques les contenant
JP2003529604A (ja) 抗プロゲステロン剤としての１７−α−置換−１１−β−置換−４−アリールおよび２１−置換１９−ノルプレグナジエンジオン
CA2010826A1 (fr) 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
IE43693B1 (en) Androstane derivatives
SE440781B (sv) Nya stereoidforeningar och anvendning derav sasom antiinflammatoriska medel
KR940008596B1 (ko) 위치 10에 이중결합 또는 삼중결합을 포함하는 기로 치환된 스테로이드류의 제조방법
HU188923B (en) Process for preparing 19-mercapto-androstane derivatives
JPH069685A (ja) １７位にメチレンラクトン基を含有する新規なステロイド、それらの製造法及び中間体、それらの薬剤としての使用並びにそれらを含有する製薬組成物
SE435186B (sv) Nya acetylenderivat av androst-4-en samt en farmaceutisk komposition
PL111825B1 (en) Process for preparing novel corticoids
SE447388B (sv) Nya diklorerade derivat av 16-alfa-metylpregnanserien, framstellning derav,anvendning derav som lekemedel och kompositioner innehallande dem
CA2045865A1 (fr) Intermediaires dans la synthese de 17-beta-acyl-3- carboxyandrosta-3,5-dienes
HU201091B (en) Process for producing gonatriene derivatives and pharmaceutical compositions comprising same
IL41454A (en) 3-keto-7(alpha,bela)-loweralkyl-delta5-androstanes and process for preparing same
RO119366B1 (ro) Derivaţi de 19-nor-progesteron cu punte etanică 14 alfa, 17 alfa
JPS6249280B2 (fr)
SE435626B (sv) Anti-inflammatorisk steroid
JPH0125759B2 (fr)
DE102006018869A1 (de) 17alpha-substituierte 4-(3-Oxoestra-4,9-dien-11beta-yl)-benzoesäure, deren Derivate und Verfahren zu ihrer Herstellung
DE3842646A1 (de) 9ss,10ss-methylensteroide

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7904431-9

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7904431-9

Format of ref document f/p: F