SE436881B - 10-halogen-e-homoeburnaner, forfarande for deras framstellning och lekemedelspreparat - Google Patents

10-halogen-e-homoeburnaner, forfarande for deras framstellning och lekemedelspreparat

Info

Publication number
SE436881B
SE436881B SE8005687A SE8005687A SE436881B SE 436881 B SE436881 B SE 436881B SE 8005687 A SE8005687 A SE 8005687A SE 8005687 A SE8005687 A SE 8005687A SE 436881 B SE436881 B SE 436881B
Authority
SE
Sweden
Prior art keywords
compounds
optically active
addition salts
general formula
acid addition
Prior art date
Application number
SE8005687A
Other languages
English (en)
Swedish (sv)
Other versions
SE8005687L (sv
Inventor
C Szantay
L Szabo
G Kalaus
L Dancsi
T Keve
F Drexler
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of SE8005687L publication Critical patent/SE8005687L/xx
Publication of SE436881B publication Critical patent/SE436881B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE8005687A 1979-08-13 1980-08-12 10-halogen-e-homoeburnaner, forfarande for deras framstellning och lekemedelspreparat SE436881B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79RI723A HU181496B (en) 1979-08-13 1979-08-13 Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes

Publications (2)

Publication Number Publication Date
SE8005687L SE8005687L (sv) 1981-02-14
SE436881B true SE436881B (sv) 1985-01-28

Family

ID=11001106

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8005687A SE436881B (sv) 1979-08-13 1980-08-12 10-halogen-e-homoeburnaner, forfarande for deras framstellning och lekemedelspreparat

Country Status (23)

Country Link
US (1) US4285950A (ja)
JP (1) JPS5629590A (ja)
AT (1) AT375940B (ja)
AU (1) AU541869B2 (ja)
BE (1) BE884472A (ja)
CA (1) CA1140121A (ja)
CH (1) CH644123A5 (ja)
DE (1) DE3026584A1 (ja)
DK (1) DK154431C (ja)
ES (1) ES8106517A1 (ja)
FI (1) FI67382C (ja)
FR (1) FR2463141A1 (ja)
GB (1) GB2058759B (ja)
HU (1) HU181496B (ja)
IL (1) IL60827A (ja)
IT (1) IT1132404B (ja)
NL (1) NL8004565A (ja)
NO (1) NO153730C (ja)
NZ (1) NZ194654A (ja)
PH (1) PH16023A (ja)
SE (1) SE436881B (ja)
SU (1) SU993819A3 (ja)
ZA (1) ZA804922B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180927B (en) * 1979-07-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing 1k-hydroximino-e-homoe-eburane de rivatives
HU180929B (en) * 1979-08-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing new bromo-vincamone derivatives
FR2487836A1 (fr) * 1980-07-31 1982-02-05 Richter Gedeon Vegyeszet Nouveaux derives halogenes du 15-hydroxy-e-homoeburnane et leur procede de preparation
HU190399B (en) * 1982-06-30 1986-08-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for the production of e-homo-eburnane-derivatives
AT383599B (de) * 1982-06-30 1987-07-27 Richter Gedeon Vegyeszet Verfahren zur herstellung von neuen racemischen und optisch aktiven e-homo-eburnan-derivaten sowievon saeureadditions-salzen derselben
US4481204A (en) * 1983-06-29 1984-11-06 Richter Gedeon Vegyeszeti Gyar R.T. E-Homo-eburnane derivatives, process for their preparation, and pharmaceutical compositions containing these compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3770724A (en) * 1970-03-31 1973-11-06 Roussel Uclaf Process for preparing pentacyclic alkaloids
FR2206090A1 (en) * 1972-11-16 1974-06-07 Omnium Chimique Sa Homovincamone-contg. medicaments - with vasodilating, spasmolytic anti-arrhythmic and anti-ischaemic properties
GB2010833B (en) * 1977-11-25 1982-04-15 Scras Homoerburnamine preparation
DE2922316A1 (de) * 1978-06-12 1979-12-20 Omnium Chimique Sa Neue halogenderivate des vincamins, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
HU177732B (en) * 1978-12-15 1981-12-28 Richter Gedeon Vegyeszet Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine
HU180927B (en) * 1979-07-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing 1k-hydroximino-e-homoe-eburane de rivatives

Also Published As

Publication number Publication date
CA1140121A (en) 1983-01-25
HU181496B (en) 1983-07-28
ES494211A0 (es) 1981-08-01
BE884472A (fr) 1981-01-26
AU6137080A (en) 1981-02-19
DE3026584A1 (de) 1981-05-07
ZA804922B (en) 1981-08-26
SU993819A3 (ru) 1983-01-30
DK154431C (da) 1989-04-10
IT8024151A0 (it) 1980-08-13
CH644123A5 (de) 1984-07-13
IL60827A (en) 1983-07-31
ATA412780A (de) 1984-02-15
JPH0227353B2 (ja) 1990-06-15
IL60827A0 (en) 1980-10-26
NO153730B (no) 1986-02-03
DK154431B (da) 1988-11-14
AT375940B (de) 1984-09-25
FI802535A (fi) 1981-02-14
NO802403L (no) 1981-02-16
FR2463141B1 (ja) 1983-11-10
FR2463141A1 (fr) 1981-02-20
GB2058759B (en) 1983-07-06
DK348080A (da) 1981-02-14
PH16023A (en) 1983-05-30
IT1132404B (it) 1986-07-02
US4285950A (en) 1981-08-25
SE8005687L (sv) 1981-02-14
NO153730C (no) 1986-05-14
GB2058759A (en) 1981-04-15
JPS5629590A (en) 1981-03-24
FI67382B (fi) 1984-11-30
ES8106517A1 (es) 1981-08-01
NL8004565A (nl) 1981-02-17
AU541869B2 (en) 1985-01-24
FI67382C (fi) 1985-03-11
NZ194654A (en) 1982-12-07

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