DK154431C - Analogifremgangsmaade til fremstilling af 10-halogen-e-homoeburnanderivater eller epimere, optisk aktive antipoder eller fysiologisk acceptable syreadditionssalte deraf - Google Patents

Analogifremgangsmaade til fremstilling af 10-halogen-e-homoeburnanderivater eller epimere, optisk aktive antipoder eller fysiologisk acceptable syreadditionssalte deraf

Info

Publication number
DK154431C
DK154431C DK348080A DK348080A DK154431C DK 154431 C DK154431 C DK 154431C DK 348080 A DK348080 A DK 348080A DK 348080 A DK348080 A DK 348080A DK 154431 C DK154431 C DK 154431C
Authority
DK
Denmark
Prior art keywords
homoeburnand
epimere
analogue
halogen
derivatives
Prior art date
Application number
DK348080A
Other languages
Danish (da)
English (en)
Other versions
DK154431B (da
DK348080A (da
Inventor
Csaba Szantay
Lajos Szabo
Gyoergy Kalaus
Lajos Dancsi
Tibor Keve
Ferenc Drexler
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of DK348080A publication Critical patent/DK348080A/da
Publication of DK154431B publication Critical patent/DK154431B/da
Application granted granted Critical
Publication of DK154431C publication Critical patent/DK154431C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK348080A 1979-08-13 1980-08-12 Analogifremgangsmaade til fremstilling af 10-halogen-e-homoeburnanderivater eller epimere, optisk aktive antipoder eller fysiologisk acceptable syreadditionssalte deraf DK154431C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU79RI723A HU181496B (en) 1979-08-13 1979-08-13 Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes
HURI000723 1979-08-13

Publications (3)

Publication Number Publication Date
DK348080A DK348080A (da) 1981-02-14
DK154431B DK154431B (da) 1988-11-14
DK154431C true DK154431C (da) 1989-04-10

Family

ID=11001106

Family Applications (1)

Application Number Title Priority Date Filing Date
DK348080A DK154431C (da) 1979-08-13 1980-08-12 Analogifremgangsmaade til fremstilling af 10-halogen-e-homoeburnanderivater eller epimere, optisk aktive antipoder eller fysiologisk acceptable syreadditionssalte deraf

Country Status (23)

Country Link
US (1) US4285950A (ja)
JP (1) JPS5629590A (ja)
AT (1) AT375940B (ja)
AU (1) AU541869B2 (ja)
BE (1) BE884472A (ja)
CA (1) CA1140121A (ja)
CH (1) CH644123A5 (ja)
DE (1) DE3026584A1 (ja)
DK (1) DK154431C (ja)
ES (1) ES8106517A1 (ja)
FI (1) FI67382C (ja)
FR (1) FR2463141A1 (ja)
GB (1) GB2058759B (ja)
HU (1) HU181496B (ja)
IL (1) IL60827A (ja)
IT (1) IT1132404B (ja)
NL (1) NL8004565A (ja)
NO (1) NO153730C (ja)
NZ (1) NZ194654A (ja)
PH (1) PH16023A (ja)
SE (1) SE436881B (ja)
SU (1) SU993819A3 (ja)
ZA (1) ZA804922B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180927B (en) * 1979-07-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing 1k-hydroximino-e-homoe-eburane de rivatives
HU180929B (en) * 1979-08-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing new bromo-vincamone derivatives
FR2487836A1 (fr) * 1980-07-31 1982-02-05 Richter Gedeon Vegyeszet Nouveaux derives halogenes du 15-hydroxy-e-homoeburnane et leur procede de preparation
HU190399B (en) * 1982-06-30 1986-08-28 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for the production of e-homo-eburnane-derivatives
AT383599B (de) * 1982-06-30 1987-07-27 Richter Gedeon Vegyeszet Verfahren zur herstellung von neuen racemischen und optisch aktiven e-homo-eburnan-derivaten sowievon saeureadditions-salzen derselben
US4481204A (en) * 1983-06-29 1984-11-06 Richter Gedeon Vegyeszeti Gyar R.T. E-Homo-eburnane derivatives, process for their preparation, and pharmaceutical compositions containing these compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3770724A (en) * 1970-03-31 1973-11-06 Roussel Uclaf Process for preparing pentacyclic alkaloids
FR2206090A1 (en) * 1972-11-16 1974-06-07 Omnium Chimique Sa Homovincamone-contg. medicaments - with vasodilating, spasmolytic anti-arrhythmic and anti-ischaemic properties
GB2010833B (en) * 1977-11-25 1982-04-15 Scras Homoerburnamine preparation
DE2922316A1 (de) * 1978-06-12 1979-12-20 Omnium Chimique Sa Neue halogenderivate des vincamins, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
HU177732B (en) * 1978-12-15 1981-12-28 Richter Gedeon Vegyeszet Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine
HU180927B (en) * 1979-07-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing 1k-hydroximino-e-homoe-eburane de rivatives

Also Published As

Publication number Publication date
CA1140121A (en) 1983-01-25
HU181496B (en) 1983-07-28
ES494211A0 (es) 1981-08-01
BE884472A (fr) 1981-01-26
AU6137080A (en) 1981-02-19
DE3026584A1 (de) 1981-05-07
ZA804922B (en) 1981-08-26
SU993819A3 (ru) 1983-01-30
IT8024151A0 (it) 1980-08-13
CH644123A5 (de) 1984-07-13
IL60827A (en) 1983-07-31
ATA412780A (de) 1984-02-15
JPH0227353B2 (ja) 1990-06-15
IL60827A0 (en) 1980-10-26
NO153730B (no) 1986-02-03
DK154431B (da) 1988-11-14
AT375940B (de) 1984-09-25
FI802535A (fi) 1981-02-14
NO802403L (no) 1981-02-16
SE436881B (sv) 1985-01-28
FR2463141B1 (ja) 1983-11-10
FR2463141A1 (fr) 1981-02-20
GB2058759B (en) 1983-07-06
DK348080A (da) 1981-02-14
PH16023A (en) 1983-05-30
IT1132404B (it) 1986-07-02
US4285950A (en) 1981-08-25
SE8005687L (sv) 1981-02-14
NO153730C (no) 1986-05-14
GB2058759A (en) 1981-04-15
JPS5629590A (en) 1981-03-24
FI67382B (fi) 1984-11-30
ES8106517A1 (es) 1981-08-01
NL8004565A (nl) 1981-02-17
AU541869B2 (en) 1985-01-24
FI67382C (fi) 1985-03-11
NZ194654A (en) 1982-12-07

Similar Documents

Publication Publication Date Title
DK149895C (da) Fremgangsmaade til fremstilling af alfa-aminoacylprolyl-ng-carboxy-argininaldehydderivater eller farmaceutisk acceptable syreadditionssalte deraf
DK149308C (da) Analogifremgangs-maade til fremstilling af trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamin-derivater eller farmaceutisk acceptablesyreadditionssalte deraf
DK462380A (da) Analogifremgangsmaade til fremstilling af 2,4-diaminoquinazolin-forbindelser eller syreadditionssalte deraf
DK151623C (da) Analogifremgangsmaade til fremstilling af n-substituerede moranolinderivater eller farmaceutisk acceptable syreadditionssalte deraf
DK149630C (da) Analogifremgangsmaade til fremstilling af tripeptidamider eller -estere eller fysiologisk acceptable syreadditionssalte deraf
DK148795C (da) Anologifremgangsmaade til fremstilling af 3-(2-morpholino-ethyl-amino)-5-phenyl-pyridazin eller farmaceutisk acceptable syreadditionssalte deraf
DK147858C (da) Analogifremgangsmaade til fremstilling af 5'-deoxy-5-fluorcytidin eller 5'-deoxy-5-fluoruridin eller fysiologisk tolerable syreadditionssalte dera
DK160045C (da) Analogifremgangsmaade til fremstilling af 4-oxo-4h-pyridooe1,2-aaapyrimidiner eller farmaceutisk acceptable syreadditionssalte eller kvaternaere ammoniumsalte deraf
DK157451C (da) Analogifremgangsmaade til fremstilling af 2,4-diamino-6-alkoxybenzyl-5-methylpyridooe2,3-daapyrimidiner eller farmaceutisk acceptable syreadditionssalte deraf
DK149841C (da) Analogifremgangsmaade til fremstilling af alfa-fluor-methyl-alfa-aminoalkansyrer eller farmaceutisk acceptable syreadditionssalte deraf
DK134580A (da) Fremgangsmaade til fremstilling af 2,6-diaminonebulariner eller syreadditionssalte deraf
DK321482A (da) Fremgangsmaade til fremstilling af 1-imidazolyl-2-phenyl-8-piperazinylphenoxy-octan-2-ol-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf
DK150597C (da) Analogifremgangsmaade til fremstilling af 3,4-bis-substituerede 1,2,5-oxadiazol-2-oxider eller farmakologisk acceptable syreadditionssalte deraf
DK15282A (da) Fremgangsmaade til fremstilling af (+)-enantiomere eller (+)(-)-racemiske 4a,9b-trans-hexahydro-1h-pyridoindol-derivater eller farmaceutisk acceptable syreadditionssalte deraf
DK165005C (da) Analogifremgangsmaade til fremstilling af 4,5-dihydro-4-oxofuran-2-carboxylsyrederivater eller terapeutisk acceptable salte deraf
DK148281C (da) Analogifremgangsmaade til fremstilling af 8a-substituerede 8,8a-desoxy-8,8a-dihydrooleandomycin-forbindelser eller farmaceutiskacceptable syreadditionssalte deraf
DK154431C (da) Analogifremgangsmaade til fremstilling af 10-halogen-e-homoeburnanderivater eller epimere, optisk aktive antipoder eller fysiologisk acceptable syreadditionssalte deraf
DK157021C (da) Analogifremgangsmaade til fremstilling af 2,3-polymethylen-4-oxo-4h-pyrido- eller -azepinooe1,2-aaapyrimidiner eller farmaceutisk acceptable syreadditionssalte eller kvaternaere salte deraf
DK146886C (da) Analogifremgangsmaade til fremstilling af basisk substituerede o-propylerede oximer eller fysiologisk acceptable syreadditionssalte deraf
DK150481C (da) Analogifremgangsmaade til fremstilling af 3',4'-dihydro-spiro-(imidazolidin-4,1'-(2'h)-naphthalen)-5-on eller farmaceutisk acceptable syreadditionssalte deraf
DK149750C (da) Analogifremgangsmaade til fremstilling af n-alkenylmoranolin-derivater eller farmaceutiske acceptable syreadditionssalte deraf
DK148036C (da) Analogifremgangsmaade til fremstilling af epimere 4''-amino-erythromycin-forbindelser eller syreadditionssalte deraf
DK151021C (da) Analogifremgangsmaade til fremstilling af 17,18-dehydro-apovincaminol-3',4',5'-trimethoxybenzoat eller farmaceutisk acceptable syreadditionssalte deraf
DK516480A (da) Fremgangsmaade til fremstilling af 2-amino-ethanol-derivater eller syreadditionssalte deraf
DK398283D0 (da) Fremgangsmade til fremstilling af 1,4-dihydropyridinderivater eller farmaceutisk acceptable syreadditionssalte deraf

Legal Events

Date Code Title Description
PBP Patent lapsed