SE0302573D0 - Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof - Google Patents

Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Info

Publication number
SE0302573D0
SE0302573D0 SE0302573A SE0302573A SE0302573D0 SE 0302573 D0 SE0302573 D0 SE 0302573D0 SE 0302573 A SE0302573 A SE 0302573A SE 0302573 A SE0302573 A SE 0302573A SE 0302573 D0 SE0302573 D0 SE 0302573D0
Authority
SE
Sweden
Prior art keywords
sup
preparation
compositions containing
benzimidazole derivatives
compounds
Prior art date
Application number
SE0302573A
Other languages
English (en)
Swedish (sv)
Inventor
Ziping Liu
Daniel Page
Christopher Walpole
Hua Yang
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0302573A priority Critical patent/SE0302573D0/xx
Publication of SE0302573D0 publication Critical patent/SE0302573D0/xx
Priority to AT04768667T priority patent/ATE430135T1/de
Priority to PT04768667T priority patent/PT1670769E/pt
Priority to NZ545736A priority patent/NZ545736A/en
Priority to PL04768667T priority patent/PL1670769T3/pl
Priority to HK06109758.7A priority patent/HK1089436B/en
Priority to UY28536A priority patent/UY28536A1/es
Priority to MYPI20043910A priority patent/MY140630A/en
Priority to EP04768667A priority patent/EP1670769B1/en
Priority to MXPA06003197A priority patent/MXPA06003197A/es
Priority to AU2004276062A priority patent/AU2004276062B2/en
Priority to PCT/GB2004/004124 priority patent/WO2005030732A1/en
Priority to TW093129150A priority patent/TW200521117A/zh
Priority to CNA2004800350086A priority patent/CN1886379A/zh
Priority to DK04768667T priority patent/DK1670769T3/da
Priority to KR1020067005825A priority patent/KR101170184B1/ko
Priority to CA2539738A priority patent/CA2539738C/en
Priority to UAA200602693A priority patent/UA86776C2/ru
Priority to HR20090388T priority patent/HRP20090388T1/xx
Priority to JP2006527490A priority patent/JP4896721B2/ja
Priority to SI200431166T priority patent/SI1670769T1/sl
Priority to DE602004020907T priority patent/DE602004020907D1/de
Priority to US10/573,054 priority patent/US8633235B2/en
Priority to RU2006113371/04A priority patent/RU2346938C2/ru
Priority to ES04768667T priority patent/ES2324669T3/es
Priority to BRPI0414780A priority patent/BRPI0414780B8/pt
Priority to CN2010105277900A priority patent/CN102010373A/zh
Priority to ARP040103467A priority patent/AR045819A1/es
Priority to SA04250310A priority patent/SA04250310B1/ar
Priority to IL174215A priority patent/IL174215A0/en
Priority to CO06028452A priority patent/CO5680443A2/es
Priority to ZA200602446A priority patent/ZA200602446B/en
Priority to IS8422A priority patent/IS8422A/is
Priority to NO20061839A priority patent/NO20061839L/no
Priority to ZA200702131A priority patent/ZA200702131B/xx
Priority to ZA200702226A priority patent/ZA200702226B/xx
Priority to CY20091100725T priority patent/CY1110332T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE0302573A 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof SE0302573D0 (sv)

Priority Applications (37)

Application Number Priority Date Filing Date Title
SE0302573A SE0302573D0 (sv) 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
JP2006527490A JP4896721B2 (ja) 2003-09-26 2004-09-24 ベンゾイミダゾール誘導体、それを含む組成物、その製造方法およびその使用
CA2539738A CA2539738C (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
PT04768667T PT1670769E (pt) 2003-09-26 2004-09-24 Derivados de benzimidazole, composições que os contêm, suas preparações e suas utilizações
NZ545736A NZ545736A (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
PL04768667T PL1670769T3 (pl) 2003-09-26 2004-09-24 Pochodne benzimidazolu, kompozycje zawierające te związki, ich wytwarzanie i zastosowanie
HK06109758.7A HK1089436B (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
UY28536A UY28536A1 (es) 2003-09-26 2004-09-24 Derivados de bencimidazol, composiciones que los contienen, preparacion y usos de los mismos.
MYPI20043910A MY140630A (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
EP04768667A EP1670769B1 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
MXPA06003197A MXPA06003197A (es) 2003-09-26 2004-09-24 Derivados de bencimidazol, composiciones que los contienen, preparacion de los mismos y usos de los mismos.
AU2004276062A AU2004276062B2 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
PCT/GB2004/004124 WO2005030732A1 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
TW093129150A TW200521117A (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
CNA2004800350086A CN1886379A (zh) 2003-09-26 2004-09-24 苯并咪唑衍生物、含它们的组合物、其制备方法和用途
DK04768667T DK1670769T3 (da) 2003-09-26 2004-09-24 Benzimidazol-derivater, sammensætninger indeholdende disse, fremstilling deraf og anvendelser deraf
KR1020067005825A KR101170184B1 (ko) 2003-09-26 2004-09-24 벤즈이미다졸 유도체, 그를 포함하는 조성물, 및 그의 제조방법 및 그의 용도
AT04768667T ATE430135T1 (de) 2003-09-26 2004-09-24 Benzimidazolderivate, zusammensetzungen, die diese enthalten, zubereitung davon und deren verwendungen
HR20090388T HRP20090388T1 (hr) 2003-09-26 2004-09-24 Derivati benzimidazola, spojevi koji ih sadrže, te njihova priprava i uporaba
UAA200602693A UA86776C2 (ru) 2003-09-26 2004-09-24 Производные бензимидазола, фармацевтическая композиция, которая их содержит, способ их получения и применение
ARP040103467A AR045819A1 (es) 2003-09-26 2004-09-24 Derivados de benzimidazol composiciones que los contienen, preparacion de los mismos y usos de los mismos
SI200431166T SI1670769T1 (sl) 2003-09-26 2004-09-24 Benzimidazolni derivati, sestavki, ki jih vsebujejo, njihova priprava in njihove uporabe
DE602004020907T DE602004020907D1 (de) 2003-09-26 2004-09-24 Benzimidazolderivate, zusammensetzungen, die diese enthalten, zubereitung davon und deren verwendungen
US10/573,054 US8633235B2 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
RU2006113371/04A RU2346938C2 (ru) 2003-09-26 2004-09-24 Производные бензимидазола, содержащие их композиции, их получение и применение
ES04768667T ES2324669T3 (es) 2003-09-26 2004-09-24 Derivados de bencimidazol, composiciones que los contienen, su preparacion y sus usos.
BRPI0414780A BRPI0414780B8 (pt) 2003-09-26 2004-09-24 composto, uso do mesmo, composição farmacêutica, e, método para preparar um composto
CN2010105277900A CN102010373A (zh) 2003-09-26 2004-09-24 苯并咪唑衍生物、含它们的组合物、其制备方法和用途
SA04250310A SA04250310B1 (ar) 2003-09-26 2004-09-26 مشتقات بنز إميدازول ، وتركيب تحتوي عليها وتحضيرها واستخداماتها
IL174215A IL174215A0 (en) 2003-09-26 2006-03-09 Benzimidazole derivatives, compositions containing them preparation thereof and uses thereof
CO06028452A CO5680443A2 (es) 2003-09-26 2006-03-22 Derivados de bencimidazol, composiciones que los contienen, preparacion de los mismos y usos de los mismos
ZA200602446A ZA200602446B (en) 2003-09-26 2006-03-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
IS8422A IS8422A (is) 2003-09-26 2006-04-21 Bensímídasólafleiður, efnablöndur sem innihalda þær, framleiðsla þeirra og notkun þeirra
NO20061839A NO20061839L (no) 2003-09-26 2006-04-26 Benzimidazolderivater, sammensetninger inneholdende dem, fremstilling derav, og anvendelse derav
ZA200702131A ZA200702131B (en) 2003-09-26 2007-03-13 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof l
ZA200702226A ZA200702226B (en) 2003-09-26 2007-03-16 Compounds, compositions containing them, preparations thereof and uses thereof II
CY20091100725T CY1110332T1 (el) 2003-09-26 2009-07-08 Παραγωγα βενζιμιδαζολης, συνθεσεις που τα περιεχουν, παρασκευη αυτων και χρηση τους

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0302573A SE0302573D0 (sv) 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Publications (1)

Publication Number Publication Date
SE0302573D0 true SE0302573D0 (sv) 2003-09-26

Family

ID=29246982

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0302573A SE0302573D0 (sv) 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Country Status (33)

Country Link
US (1) US8633235B2 (enExample)
EP (1) EP1670769B1 (enExample)
JP (1) JP4896721B2 (enExample)
KR (1) KR101170184B1 (enExample)
CN (2) CN102010373A (enExample)
AR (1) AR045819A1 (enExample)
AT (1) ATE430135T1 (enExample)
AU (1) AU2004276062B2 (enExample)
BR (1) BRPI0414780B8 (enExample)
CA (1) CA2539738C (enExample)
CO (1) CO5680443A2 (enExample)
CY (1) CY1110332T1 (enExample)
DE (1) DE602004020907D1 (enExample)
DK (1) DK1670769T3 (enExample)
ES (1) ES2324669T3 (enExample)
HR (1) HRP20090388T1 (enExample)
IL (1) IL174215A0 (enExample)
IS (1) IS8422A (enExample)
MX (1) MXPA06003197A (enExample)
MY (1) MY140630A (enExample)
NO (1) NO20061839L (enExample)
NZ (1) NZ545736A (enExample)
PL (1) PL1670769T3 (enExample)
PT (1) PT1670769E (enExample)
RU (1) RU2346938C2 (enExample)
SA (1) SA04250310B1 (enExample)
SE (1) SE0302573D0 (enExample)
SI (1) SI1670769T1 (enExample)
TW (1) TW200521117A (enExample)
UA (1) UA86776C2 (enExample)
UY (1) UY28536A1 (enExample)
WO (1) WO2005030732A1 (enExample)
ZA (3) ZA200602446B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1558252B1 (en) 2002-08-02 2007-10-10 Merck & Co., Inc. Substituted furo [2,3-b]pyridine derivatives
SE0302573D0 (sv) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
RU2374234C2 (ru) 2004-09-24 2009-11-27 Астразенека Аб Бензимидазольные производные, содержащие их композиции, их получение и применение
CN101065375A (zh) * 2004-09-24 2007-10-31 阿斯利康(瑞典)有限公司 化合物、包含该化合物的组合物、其制备及其应用
AU2005287427B2 (en) * 2004-09-24 2009-03-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof I
CA2582507A1 (en) * 2004-09-24 2006-03-30 Astrazeneca Ab Compounds, compositions containing them, preparation thereof and uses thereof iii
WO2006048754A1 (en) 2004-11-02 2006-05-11 Pfizer Japan Inc. Sulfonyl benzimidazole derivatives
CN101233098A (zh) * 2005-07-29 2008-07-30 阿斯利康(瑞典)有限公司 成对((二氟环烷基)甲基)胺的制备方法
TW200745049A (en) * 2006-03-23 2007-12-16 Astrazeneca Ab New crystalline forms
TW200808769A (en) 2006-04-18 2008-02-16 Astrazeneca Ab Therapeutic compounds
US20080139846A1 (en) * 2006-09-01 2008-06-12 Astrazeneca Ab New Process 298
JP5159630B2 (ja) * 2006-09-13 2013-03-06 協和発酵キリン株式会社 縮環複素環誘導体
US20110086853A1 (en) * 2009-10-08 2011-04-14 William Brown Therapeutic Compounds
RU2414899C1 (ru) * 2009-12-29 2011-03-27 Аверин Константин Михайлович Средства для лечения рассеянного склероза
RU2454234C1 (ru) * 2011-03-16 2012-06-27 Константин Михайлович Аверин Соли 1,3-диэтилбензимидазолия - иммуностимулирующие средства и фармацевтические композиции на их основе
AU2013274385B2 (en) * 2012-06-13 2017-11-30 Cytec Technology Corp. Stabilizer compositions containing substituted chroman compounds and methods of use
HRP20161745T1 (hr) 2012-06-26 2017-02-24 Bayer Pharma Aktiengesellschaft N-[4-(kinolin-4-iloksi)cikloheksil(methil)](hetero)arilkarboksamidi kao antagonisti receptora androgena, njihova proizvodnja i uporaba kao medicinskih proizvoda
AU2019232437A1 (en) 2018-03-07 2020-10-08 Bayer Aktiengesellschaft Identification and use of ERK5 inhibitors
US20220227729A1 (en) 2019-05-21 2022-07-21 Bayer Aktiengesellschaft Identification and use of kras inhibitors
CN112010789A (zh) * 2019-05-31 2020-12-01 中国科学院上海药物研究所 乙烯基磺酰胺或乙烯基酰胺类化合物及其制备方法和用途
GB202019335D0 (en) * 2020-12-08 2021-01-20 Artelo Biosciences Ltd Pharmaceutical compositions
WO2023166450A1 (ko) * 2022-03-04 2023-09-07 삼진제약주식회사 신규한 헤테로 고리 화합물 및 이를 포함하는 약학적 조성물

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1604908A (en) 1965-06-24 1971-05-15 Substd benzimidazoles - with anthelmintic,fungicidal activity and some with antiviral and antibacterial activity
FR5354M (enExample) 1965-09-10 1967-09-11
US5387600A (en) 1992-07-30 1995-02-07 Fuji Photo Film Co., Ltd. Treating arteriosclerosis using benzimidazole compositions
DE4237597A1 (de) 1992-11-06 1994-05-11 Bayer Ag Substituierte Benzimidazole
DE4237617A1 (de) * 1992-11-06 1994-05-11 Bayer Ag Verwendung von substituierten Benzimidazolen
DE4237557A1 (de) 1992-11-06 1994-05-11 Bayer Ag Substituierte Benzimidazole
IL124969A (en) 1995-12-28 2002-09-12 Fujisawa Pharmaceutical Co History of benzimidazole, processes for their preparation and pharmaceutical preparations containing them
TW453999B (en) * 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
US6348032B1 (en) * 1998-11-23 2002-02-19 Cell Pathways, Inc. Method of inhibiting neoplastic cells with benzimidazole derivatives
US6534535B1 (en) * 1999-08-12 2003-03-18 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
US6632815B2 (en) * 1999-09-17 2003-10-14 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
US6844367B1 (en) * 1999-09-17 2005-01-18 Millennium Pharmaceuticals, Inc. Benzamides and related inhibitors of factor Xa
US6720317B1 (en) * 1999-09-17 2004-04-13 Millennium Pharmaceuticals, Inc. Inhibitors of factor Xa
NZ517828A (en) 1999-09-17 2003-10-31 Millennium Pharm Inc Inhibitors having activity against mammalian factor Xa
KR100703908B1 (ko) * 2000-01-14 2007-04-05 바이엘 쉐링 파마 악티엔게젤샤프트 미세교세포 활성화와 관련된 질병의 치료를 위한1,2-디아릴 벤즈이미다졸
US7115645B2 (en) * 2000-01-14 2006-10-03 Schering Aktiengesellschaft 1,2 diarylbenzimidazoles and their pharmaceutical use
US7329679B2 (en) * 2000-01-27 2008-02-12 Schering Aktiengesellschaft 1,2 Diarylbenzimidazoles and their pharmaceutical use
ES2254385T3 (es) * 2000-02-29 2006-06-16 Millennium Pharmaceuticals, Inc. Benzamidas e inhibidores relacionados del factor xa.
AU2001273040A1 (en) 2000-06-27 2002-01-08 Du Pont Pharmaceuticals Company Factor xa inhibitors
WO2002046168A1 (en) 2000-12-07 2002-06-13 Astrazeneca Ab Therapeutic benzimidazole compounds
SE0101387D0 (sv) * 2001-04-20 2001-04-20 Astrazeneca Ab Novel compounds
JPWO2002100833A1 (ja) 2001-06-12 2004-09-24 住友製薬株式会社 Ｒｈｏキナーゼ阻害剤
TW200505902A (en) 2003-03-20 2005-02-16 Schering Corp Cannabinoid receptor ligands
SE0301701D0 (sv) * 2003-06-10 2003-06-10 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0301699D0 (sv) * 2003-06-10 2003-06-10 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
WO2005007625A2 (en) 2003-07-14 2005-01-27 The University Of Tennessee Research Foundation Heterocyclic amides with anti-tuberculosis activity
WO2005021547A2 (en) 2003-08-28 2005-03-10 Pharmaxis Pty Ltd. Heterocyclic cannabinoid cb2 receptor antagonists
SE0302573D0 (sv) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302571D0 (sv) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302572D0 (sv) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302570D0 (sv) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
JP2007538106A (ja) 2004-05-20 2007-12-27 イーラン ファーマスーティカルズ、インコーポレイテッド γセクレターゼのＮ−環式スルホンアミド阻害剤
US20060135773A1 (en) 2004-06-17 2006-06-22 Semple Joseph E Trisubstituted nitrogen modulators of tyrosine phosphatases
SG155188A1 (en) 2004-07-30 2009-09-30 Exelixis Inc Pyrrole derivatives as pharmaceutical agents
US20060052421A1 (en) * 2004-09-09 2006-03-09 Eastman Kodak Company Conjugation agent
EP1797075A1 (en) 2004-09-24 2007-06-20 AstraZeneca AB Benzimidazole derivatives and their use as cannabinoid receptor ligands
WO2006033632A1 (en) 2004-09-24 2006-03-30 Astrazeneca Ab Benzimidazole derivatives and their use as cannabinoid receptor ligands I
JP2008514589A (ja) 2004-09-24 2008-05-08 アストラゼネカ・アクチエボラーグ 化合物、それらを含有する組成物、それらの製造及びそれらの使用ｉｉｉｉ
EP1797070A1 (en) 2004-09-24 2007-06-20 AstraZeneca AB Compounds, compositions containing them, preparations thereof and uses thereof ii
RU2374234C2 (ru) * 2004-09-24 2009-11-27 Астразенека Аб Бензимидазольные производные, содержащие их композиции, их получение и применение
CA2582507A1 (en) 2004-09-24 2006-03-30 Astrazeneca Ab Compounds, compositions containing them, preparation thereof and uses thereof iii
JP2008514590A (ja) 2004-09-24 2008-05-08 アストラゼネカ・アクチエボラーグ ベンゾイミダゾール誘導体、それを含む組成物、その製造方法及びその使用
AU2005287427B2 (en) 2004-09-24 2009-03-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof I
WO2006048754A1 (en) 2004-11-02 2006-05-11 Pfizer Japan Inc. Sulfonyl benzimidazole derivatives
WO2006078941A2 (en) 2005-01-20 2006-07-27 Sirtris Pharmaceuticals, Inc. Novel sirtuin activating compounds and methods of use thereof
TW200745049A (en) 2006-03-23 2007-12-16 Astrazeneca Ab New crystalline forms
TW200808769A (en) * 2006-04-18 2008-02-16 Astrazeneca Ab Therapeutic compounds
TW200808772A (en) * 2006-06-13 2008-02-16 Astrazeneca Ab Therapeutic compounds

Also Published As

Publication number Publication date
PL1670769T3 (pl) 2009-09-30
IL174215A0 (en) 2006-08-01
ZA200602446B (en) 2007-09-26
CO5680443A2 (es) 2006-09-29
HRP20090388T1 (hr) 2009-08-31
TW200521117A (en) 2005-07-01
ES2324669T3 (es) 2009-08-12
SI1670769T1 (sl) 2009-10-31
IS8422A (is) 2006-04-21
PT1670769E (pt) 2009-07-09
AU2004276062A1 (en) 2005-04-07
MXPA06003197A (es) 2006-06-23
RU2346938C2 (ru) 2009-02-20
US20080207612A1 (en) 2008-08-28
BRPI0414780A (pt) 2006-11-21
HK1089436A1 (en) 2006-12-01
CA2539738C (en) 2011-11-22
NZ545736A (en) 2009-11-27
WO2005030732A1 (en) 2005-04-07
NO20061839L (no) 2006-06-26
EP1670769A1 (en) 2006-06-21
CN102010373A (zh) 2011-04-13
KR20070001052A (ko) 2007-01-03
ATE430135T1 (de) 2009-05-15
JP4896721B2 (ja) 2012-03-14
SA04250310B1 (ar) 2009-01-19
ZA200702226B (en) 2009-01-28
AU2004276062B2 (en) 2008-05-22
CN1886379A (zh) 2006-12-27
CA2539738A1 (en) 2005-04-07
UA86776C2 (ru) 2009-05-25
BRPI0414780B1 (pt) 2018-10-23
DK1670769T3 (da) 2009-08-10
EP1670769B1 (en) 2009-04-29
RU2006113371A (ru) 2007-11-10
ZA200702131B (en) 2008-08-27
DE602004020907D1 (de) 2009-06-10
JP2007506721A (ja) 2007-03-22
US8633235B2 (en) 2014-01-21
KR101170184B1 (ko) 2012-07-31
BRPI0414780B8 (pt) 2021-05-25
UY28536A1 (es) 2005-04-29
AR045819A1 (es) 2005-11-16
MY140630A (en) 2010-01-15
CY1110332T1 (el) 2015-01-14

Similar Documents

Publication Publication Date Title
SE0302573D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0402762D0 (sv) Indazole sulphonamide derivatives
SE0401971D0 (sv) Piperidne derivatives
WO2004060882A8 (en) Cb 1/cb 2 receptor ligands and their use in the treatment of pain
SE0401345D0 (sv) Therapeutic compounds: Pyridine as scaffold
SE0401342D0 (sv) Therapeutic compounds
SE9900961D0 (sv) Novel compounds
SE0300908D0 (sv) Azaindole derivatives, preparations thereof, uses thereof and compositions containing them
SE0104250D0 (sv) Heterocyclic compounds
SE0301701D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0301699D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302570D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0203303D0 (sv) Novel Compounds
SE0302572D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0300105D0 (sv) Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof
SE0203300D0 (sv) Novel Compounds
UY27587A1 (es) Heterociclos terapéuticos
TW200626581A (en) Compounds, compositions containing them, preparation thereof and uses thereof
SE0302571D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0400027D0 (sv) Diarylmethyl piperazine derivatives, preparations thereof and uses thereof
SE0300103D0 (sv) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0301445D0 (sv) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0300104D0 (sv) Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof
SE0400285D0 (sv) Pyrroloquinoline and piperidoquinoline derivatives, preparation thereof, compositions containing them and uses thereof
SE0301698D0 (sv) Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof