PL1670769T3 - Pochodne benzimidazolu, kompozycje zawierające te związki, ich wytwarzanie i zastosowanie - Google Patents

Pochodne benzimidazolu, kompozycje zawierające te związki, ich wytwarzanie i zastosowanie

Info

Publication number
PL1670769T3
PL1670769T3 PL04768667T PL04768667T PL1670769T3 PL 1670769 T3 PL1670769 T3 PL 1670769T3 PL 04768667 T PL04768667 T PL 04768667T PL 04768667 T PL04768667 T PL 04768667T PL 1670769 T3 PL1670769 T3 PL 1670769T3
Authority
PL
Poland
Prior art keywords
preparation
compositions containing
benzimidazole derivatives
benzimidazole
derivatives
Prior art date
Application number
PL04768667T
Other languages
English (en)
Inventor
Ziping Liu
Daniel Page
Christopher Walpole
Hua Yang
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PL1670769T3 publication Critical patent/PL1670769T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08Radicals containing only hydrogen and carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14Radicals substituted by nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL04768667T 2003-09-26 2004-09-24 Pochodne benzimidazolu, kompozycje zawierające te związki, ich wytwarzanie i zastosowanie PL1670769T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0302573A SE0302573D0 (sv) 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
EP04768667A EP1670769B1 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
PCT/GB2004/004124 WO2005030732A1 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Publications (1)

Publication Number Publication Date
PL1670769T3 true PL1670769T3 (pl) 2009-09-30

Family

ID=29246982

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04768667T PL1670769T3 (pl) 2003-09-26 2004-09-24 Pochodne benzimidazolu, kompozycje zawierające te związki, ich wytwarzanie i zastosowanie

Country Status (34)

Country Link
US (1) US8633235B2 (pl)
EP (1) EP1670769B1 (pl)
JP (1) JP4896721B2 (pl)
KR (1) KR101170184B1 (pl)
CN (2) CN102010373A (pl)
AR (1) AR045819A1 (pl)
AT (1) ATE430135T1 (pl)
AU (1) AU2004276062B2 (pl)
BR (1) BRPI0414780B8 (pl)
CA (1) CA2539738C (pl)
CO (1) CO5680443A2 (pl)
CY (1) CY1110332T1 (pl)
DE (1) DE602004020907D1 (pl)
DK (1) DK1670769T3 (pl)
ES (1) ES2324669T3 (pl)
HK (1) HK1089436A1 (pl)
HR (1) HRP20090388T1 (pl)
IL (1) IL174215A0 (pl)
IS (1) IS8422A (pl)
MX (1) MXPA06003197A (pl)
MY (1) MY140630A (pl)
NO (1) NO20061839L (pl)
NZ (1) NZ545736A (pl)
PL (1) PL1670769T3 (pl)
PT (1) PT1670769E (pl)
RU (1) RU2346938C2 (pl)
SA (1) SA04250310B1 (pl)
SE (1) SE0302573D0 (pl)
SI (1) SI1670769T1 (pl)
TW (1) TW200521117A (pl)
UA (1) UA86776C2 (pl)
UY (1) UY28536A1 (pl)
WO (1) WO2005030732A1 (pl)
ZA (3) ZA200602446B (pl)

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CA2581232C (en) * 2004-09-24 2015-04-07 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof i
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US20110086853A1 (en) * 2009-10-08 2011-04-14 William Brown Therapeutic Compounds
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WO2020234103A1 (en) 2019-05-21 2020-11-26 Bayer Aktiengesellschaft Identification and use of kras inhibitors
CN112010789A (zh) * 2019-05-31 2020-12-01 中国科学院上海药物研究所 乙烯基磺酰胺或乙烯基酰胺类化合物及其制备方法和用途
WO2023166450A1 (ko) * 2022-03-04 2023-09-07 삼진제약주식회사 신규한 헤테로 고리 화합물 및 이를 포함하는 약학적 조성물

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Also Published As

Publication number Publication date
CY1110332T1 (el) 2015-01-14
US20080207612A1 (en) 2008-08-28
UY28536A1 (es) 2005-04-29
ZA200702226B (en) 2009-01-28
BRPI0414780B8 (pt) 2021-05-25
EP1670769A1 (en) 2006-06-21
BRPI0414780A (pt) 2006-11-21
US8633235B2 (en) 2014-01-21
NZ545736A (en) 2009-11-27
SA04250310B1 (ar) 2009-01-19
HK1089436A1 (en) 2006-12-01
MY140630A (en) 2010-01-15
ES2324669T3 (es) 2009-08-12
AU2004276062B2 (en) 2008-05-22
DK1670769T3 (da) 2009-08-10
JP2007506721A (ja) 2007-03-22
RU2006113371A (ru) 2007-11-10
NO20061839L (no) 2006-06-26
IS8422A (is) 2006-04-21
IL174215A0 (en) 2006-08-01
ATE430135T1 (de) 2009-05-15
KR20070001052A (ko) 2007-01-03
SI1670769T1 (sl) 2009-10-31
SE0302573D0 (sv) 2003-09-26
UA86776C2 (ru) 2009-05-25
WO2005030732A1 (en) 2005-04-07
KR101170184B1 (ko) 2012-07-31
PT1670769E (pt) 2009-07-09
AU2004276062A1 (en) 2005-04-07
DE602004020907D1 (de) 2009-06-10
CN102010373A (zh) 2011-04-13
AR045819A1 (es) 2005-11-16
BRPI0414780B1 (pt) 2018-10-23
MXPA06003197A (es) 2006-06-23
EP1670769B1 (en) 2009-04-29
RU2346938C2 (ru) 2009-02-20
HRP20090388T1 (en) 2009-08-31
CA2539738C (en) 2011-11-22
ZA200602446B (en) 2007-09-26
JP4896721B2 (ja) 2012-03-14
CA2539738A1 (en) 2005-04-07
ZA200702131B (en) 2008-08-27
CN1886379A (zh) 2006-12-27
CO5680443A2 (es) 2006-09-29
TW200521117A (en) 2005-07-01

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