SE0302573D0 - Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof - Google Patents

Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Info

Publication number
SE0302573D0
SE0302573D0 SE0302573A SE0302573A SE0302573D0 SE 0302573 D0 SE0302573 D0 SE 0302573D0 SE 0302573 A SE0302573 A SE 0302573A SE 0302573 A SE0302573 A SE 0302573A SE 0302573 D0 SE0302573 D0 SE 0302573D0
Authority
SE
Sweden
Prior art keywords
sup
preparation
compositions containing
benzimidazole derivatives
compounds
Prior art date
Application number
SE0302573A
Other languages
English (en)
Swedish (sv)
Inventor
Ziping Liu
Daniel Page
Christopher Walpole
Hua Yang
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0302573A priority Critical patent/SE0302573D0/xx
Publication of SE0302573D0 publication Critical patent/SE0302573D0/xx
Priority to CN2010105277900A priority patent/CN102010373A/zh
Priority to AU2004276062A priority patent/AU2004276062B2/en
Priority to AT04768667T priority patent/ATE430135T1/de
Priority to MYPI20043910A priority patent/MY140630A/en
Priority to MXPA06003197A priority patent/MXPA06003197A/es
Priority to NZ545736A priority patent/NZ545736A/en
Priority to BRPI0414780A priority patent/BRPI0414780B8/pt
Priority to DK04768667T priority patent/DK1670769T3/da
Priority to EP04768667A priority patent/EP1670769B1/en
Priority to TW093129150A priority patent/TW200521117A/zh
Priority to CA2539738A priority patent/CA2539738C/en
Priority to ES04768667T priority patent/ES2324669T3/es
Priority to DE602004020907T priority patent/DE602004020907D1/de
Priority to US10/573,054 priority patent/US8633235B2/en
Priority to CNA2004800350086A priority patent/CN1886379A/zh
Priority to PT04768667T priority patent/PT1670769E/pt
Priority to SI200431166T priority patent/SI1670769T1/sl
Priority to RU2006113371/04A priority patent/RU2346938C2/ru
Priority to UY28536A priority patent/UY28536A1/es
Priority to ARP040103467A priority patent/AR045819A1/es
Priority to UAA200602693A priority patent/UA86776C2/ru
Priority to JP2006527490A priority patent/JP4896721B2/ja
Priority to PCT/GB2004/004124 priority patent/WO2005030732A1/en
Priority to KR1020067005825A priority patent/KR101170184B1/ko
Priority to PL04768667T priority patent/PL1670769T3/pl
Priority to SA04250310A priority patent/SA04250310B1/ar
Priority to IL174215A priority patent/IL174215A0/en
Priority to CO06028452A priority patent/CO5680443A2/es
Priority to ZA200602446A priority patent/ZA200602446B/en
Priority to IS8422A priority patent/IS8422A/is
Priority to NO20061839A priority patent/NO20061839L/no
Priority to HK06109758.7A priority patent/HK1089436A1/xx
Priority to ZA200702131A priority patent/ZA200702131B/xx
Priority to ZA200702226A priority patent/ZA200702226B/xx
Priority to HR20090388T priority patent/HRP20090388T1/xx
Priority to CY20091100725T priority patent/CY1110332T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE0302573A 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof SE0302573D0 (sv)

Priority Applications (37)

Application Number Priority Date Filing Date Title
SE0302573A SE0302573D0 (sv) 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
PL04768667T PL1670769T3 (pl) 2003-09-26 2004-09-24 Pochodne benzimidazolu, kompozycje zawierające te związki, ich wytwarzanie i zastosowanie
PT04768667T PT1670769E (pt) 2003-09-26 2004-09-24 Derivados de benzimidazole, composições que os contêm, suas preparações e suas utilizações
UY28536A UY28536A1 (es) 2003-09-26 2004-09-24 Derivados de bencimidazol, composiciones que los contienen, preparacion y usos de los mismos.
SI200431166T SI1670769T1 (sl) 2003-09-26 2004-09-24 Benzimidazolni derivati, sestavki, ki jih vsebujejo, njihova priprava in njihove uporabe
AU2004276062A AU2004276062B2 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
MXPA06003197A MXPA06003197A (es) 2003-09-26 2004-09-24 Derivados de bencimidazol, composiciones que los contienen, preparacion de los mismos y usos de los mismos.
NZ545736A NZ545736A (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
BRPI0414780A BRPI0414780B8 (pt) 2003-09-26 2004-09-24 composto, uso do mesmo, composição farmacêutica, e, método para preparar um composto
DK04768667T DK1670769T3 (da) 2003-09-26 2004-09-24 Benzimidazol-derivater, sammensætninger indeholdende disse, fremstilling deraf og anvendelser deraf
EP04768667A EP1670769B1 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
TW093129150A TW200521117A (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
CA2539738A CA2539738C (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
ES04768667T ES2324669T3 (es) 2003-09-26 2004-09-24 Derivados de bencimidazol, composiciones que los contienen, su preparacion y sus usos.
DE602004020907T DE602004020907D1 (de) 2003-09-26 2004-09-24 Benzimidazolderivate, zusammensetzungen, die diese enthalten, zubereitung davon und deren verwendungen
US10/573,054 US8633235B2 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
CNA2004800350086A CN1886379A (zh) 2003-09-26 2004-09-24 苯并咪唑衍生物、含它们的组合物、其制备方法和用途
CN2010105277900A CN102010373A (zh) 2003-09-26 2004-09-24 苯并咪唑衍生物、含它们的组合物、其制备方法和用途
AT04768667T ATE430135T1 (de) 2003-09-26 2004-09-24 Benzimidazolderivate, zusammensetzungen, die diese enthalten, zubereitung davon und deren verwendungen
MYPI20043910A MY140630A (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
RU2006113371/04A RU2346938C2 (ru) 2003-09-26 2004-09-24 Производные бензимидазола, содержащие их композиции, их получение и применение
ARP040103467A AR045819A1 (es) 2003-09-26 2004-09-24 Derivados de benzimidazol composiciones que los contienen, preparacion de los mismos y usos de los mismos
UAA200602693A UA86776C2 (ru) 2003-09-26 2004-09-24 Производные бензимидазола, фармацевтическая композиция, которая их содержит, способ их получения и применение
JP2006527490A JP4896721B2 (ja) 2003-09-26 2004-09-24 ベンゾイミダゾール誘導体、それを含む組成物、その製造方法およびその使用
PCT/GB2004/004124 WO2005030732A1 (en) 2003-09-26 2004-09-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
KR1020067005825A KR101170184B1 (ko) 2003-09-26 2004-09-24 벤즈이미다졸 유도체, 그를 포함하는 조성물, 및 그의 제조방법 및 그의 용도
SA04250310A SA04250310B1 (ar) 2003-09-26 2004-09-26 مشتقات بنز إميدازول ، وتركيب تحتوي عليها وتحضيرها واستخداماتها
IL174215A IL174215A0 (en) 2003-09-26 2006-03-09 Benzimidazole derivatives, compositions containing them preparation thereof and uses thereof
CO06028452A CO5680443A2 (es) 2003-09-26 2006-03-22 Derivados de bencimidazol, composiciones que los contienen, preparacion de los mismos y usos de los mismos
ZA200602446A ZA200602446B (en) 2003-09-26 2006-03-24 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
IS8422A IS8422A (is) 2003-09-26 2006-04-21 Bensímídasólafleiður, efnablöndur sem innihalda þær, framleiðsla þeirra og notkun þeirra
NO20061839A NO20061839L (no) 2003-09-26 2006-04-26 Benzimidazolderivater, sammensetninger inneholdende dem, fremstilling derav, og anvendelse derav
HK06109758.7A HK1089436A1 (en) 2003-09-26 2006-09-01 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
ZA200702131A ZA200702131B (en) 2003-09-26 2007-03-13 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof l
ZA200702226A ZA200702226B (en) 2003-09-26 2007-03-16 Compounds, compositions containing them, preparations thereof and uses thereof II
HR20090388T HRP20090388T1 (en) 2003-09-26 2009-07-07 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
CY20091100725T CY1110332T1 (el) 2003-09-26 2009-07-08 Παραγωγα βενζιμιδαζολης, συνθεσεις που τα περιεχουν, παρασκευη αυτων και χρηση τους

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0302573A SE0302573D0 (sv) 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Publications (1)

Publication Number Publication Date
SE0302573D0 true SE0302573D0 (sv) 2003-09-26

Family

ID=29246982

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0302573A SE0302573D0 (sv) 2003-09-26 2003-09-26 Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof

Country Status (34)

Country Link
US (1) US8633235B2 (xx)
EP (1) EP1670769B1 (xx)
JP (1) JP4896721B2 (xx)
KR (1) KR101170184B1 (xx)
CN (2) CN102010373A (xx)
AR (1) AR045819A1 (xx)
AT (1) ATE430135T1 (xx)
AU (1) AU2004276062B2 (xx)
BR (1) BRPI0414780B8 (xx)
CA (1) CA2539738C (xx)
CO (1) CO5680443A2 (xx)
CY (1) CY1110332T1 (xx)
DE (1) DE602004020907D1 (xx)
DK (1) DK1670769T3 (xx)
ES (1) ES2324669T3 (xx)
HK (1) HK1089436A1 (xx)
HR (1) HRP20090388T1 (xx)
IL (1) IL174215A0 (xx)
IS (1) IS8422A (xx)
MX (1) MXPA06003197A (xx)
MY (1) MY140630A (xx)
NO (1) NO20061839L (xx)
NZ (1) NZ545736A (xx)
PL (1) PL1670769T3 (xx)
PT (1) PT1670769E (xx)
RU (1) RU2346938C2 (xx)
SA (1) SA04250310B1 (xx)
SE (1) SE0302573D0 (xx)
SI (1) SI1670769T1 (xx)
TW (1) TW200521117A (xx)
UA (1) UA86776C2 (xx)
UY (1) UY28536A1 (xx)
WO (1) WO2005030732A1 (xx)
ZA (3) ZA200602446B (xx)

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AU2003257145B2 (en) 2002-08-02 2008-11-13 Merck Sharp & Dohme Corp. Substituted furo (2,3-b) pyridine derivatives
SE0302573D0 (sv) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
KR101269869B1 (ko) 2004-09-24 2013-06-07 네오메드 인스티튜트 벤즈이미다졸 유도체, 그를 함유하는 조성물, 그의 제조방법 및 그의 용도
CA2582507A1 (en) * 2004-09-24 2006-03-30 Astrazeneca Ab Compounds, compositions containing them, preparation thereof and uses thereof iii
AU2005287427B2 (en) * 2004-09-24 2009-03-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof I
UA87327C2 (ru) * 2004-09-24 2009-07-10 Астразенека Аб Производные бензимидазола, композиция, которая их содержит, их получение и применение
ATE417830T1 (de) 2004-11-02 2009-01-15 Pfizer Sulfonylbenzimidazolderivate
CN101233098A (zh) * 2005-07-29 2008-07-30 阿斯利康(瑞典)有限公司 成对((二氟环烷基)甲基)胺的制备方法
TW200745049A (en) * 2006-03-23 2007-12-16 Astrazeneca Ab New crystalline forms
TW200808769A (en) 2006-04-18 2008-02-16 Astrazeneca Ab Therapeutic compounds
US20080139846A1 (en) * 2006-09-01 2008-06-12 Astrazeneca Ab New Process 298
WO2008032764A1 (fr) * 2006-09-13 2008-03-20 Kyowa Hakko Kirin Co., Ltd. Dérivé hétérocyclique fusionné
US20110086853A1 (en) * 2009-10-08 2011-04-14 William Brown Therapeutic Compounds
RU2454234C1 (ru) * 2011-03-16 2012-06-27 Константин Михайлович Аверин Соли 1,3-диэтилбензимидазолия - иммуностимулирующие средства и фармацевтические композиции на их основе
NZ726849A (en) * 2012-06-13 2018-06-29 Cytec Tech Corp Stabilizer compositions containing substituted chroman compounds and methods of use
PL2864291T3 (pl) 2012-06-26 2017-07-31 Bayer Pharma Aktiengesellschaft N-[4-(chinolin-4-yloksy)cykloheksylo(metylo)](hetero)arylokarboksyamidy jako antagoniści receptora androgenowego, ich wytwarzanie i zastosowanie jako produktów medycznych
WO2019170543A1 (en) 2018-03-07 2019-09-12 Bayer Aktiengesellschaft Identification and use of erk5 inhibitors
WO2020234103A1 (en) 2019-05-21 2020-11-26 Bayer Aktiengesellschaft Identification and use of kras inhibitors
CN112010789A (zh) * 2019-05-31 2020-12-01 中国科学院上海药物研究所 乙烯基磺酰胺或乙烯基酰胺类化合物及其制备方法和用途
KR20230131133A (ko) * 2022-03-04 2023-09-12 삼진제약주식회사 신규한 헤테로 고리 화합물 및 이를 포함하는 약학적 조성물

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CA2539738A1 (en) 2005-04-07
ATE430135T1 (de) 2009-05-15
CA2539738C (en) 2011-11-22
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AU2004276062B2 (en) 2008-05-22
IL174215A0 (en) 2006-08-01
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