RU2733897C2 - Стабильные полипептиды, связывающиеся с с5 комплемента человека - Google Patents
Стабильные полипептиды, связывающиеся с с5 комплемента человека Download PDFInfo
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- RU2733897C2 RU2733897C2 RU2016111115A RU2016111115A RU2733897C2 RU 2733897 C2 RU2733897 C2 RU 2733897C2 RU 2016111115 A RU2016111115 A RU 2016111115A RU 2016111115 A RU2016111115 A RU 2016111115A RU 2733897 C2 RU2733897 C2 RU 2733897C2
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- Prior art keywords
- leu
- asp
- glu
- ala
- ile
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| SE1350986 | 2013-08-28 | ||
| SE1350986-4 | 2013-08-28 | ||
| PCT/EP2014/068282 WO2015028558A1 (en) | 2013-08-28 | 2014-08-28 | Stable polypeptides binding to human complement c5 |
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| RU2020128977A Division RU2020128977A (ru) | 2013-08-28 | 2014-08-28 | Стабильные полипептиды, связывающиеся с с5 комплемента человека |
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| RU2016111115A RU2016111115A (ru) | 2017-10-03 |
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| RU2020128977A RU2020128977A (ru) | 2013-08-28 | 2014-08-28 | Стабильные полипептиды, связывающиеся с с5 комплемента человека |
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| JP6276202B2 (ja) | 2012-02-20 | 2018-02-07 | スウェディッシュ・オーファン・バイオヴィトラム・アーベー（ペーウーベーエル） | ヒト補体ｃ５に結合するポリペプチド |
| PT3038633T (pt) * | 2013-08-28 | 2021-01-14 | Ipc Res Llc | Polipéptidos estáveis que se ligam ao complemento humano c5 |
| JP7138411B2 (ja) * | 2013-08-28 | 2022-09-16 | アフィボディ・アーベー | 変異した骨格を有する結合ポリペプチド |
| UY37651A (es) * | 2017-03-31 | 2018-10-31 | Swedish Orphan Biovitrum Ab Publ | Polipéptido de unión al il-1r-i |
| KR20250068795A (ko) | 2017-07-11 | 2025-05-16 | 알렉시온 파마슈티칼스, 인코포레이티드 | 보체 성분 c5 또는 혈청 알부민에 결합하는 폴리펩티드 및 그의 융합 단백질 |
| US20240124533A1 (en) * | 2021-02-15 | 2024-04-18 | Affibody Ab | New her2-binding polypeptide |
| MX2024005285A (es) * | 2021-11-01 | 2024-09-18 | Ipc Res Llc | Administracion de proteinas de union a c5. |
| WO2024227886A1 (en) | 2023-05-02 | 2024-11-07 | Mebrahtu Aman | Bispecific binding molecule |
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| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US6074642A (en) | 1994-05-02 | 2000-06-13 | Alexion Pharmaceuticals, Inc. | Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis |
| CA2424379C (en) | 2000-10-10 | 2013-10-01 | Tanox, Inc. | Inhibition of complement c5 activation for the treatment and prevention of delayed xenograft or acute vascular rejection |
| BRPI0211953B8 (pt) | 2001-08-17 | 2021-05-25 | Genentech Inc | anticorpo monoclonal ou fragmento de ligação a antígeno que se liga a c5 e c5a sem a prevenção da formação de c5b, linhagem celular, composição farmacêutica, bem como método in vitro para inibir a atividade de c5a e método de diagnóstico in vitro |
| ITMI20021527A1 (it) | 2002-07-11 | 2004-01-12 | Consiglio Nazionale Ricerche | Anticorpi anti componente c5 del complemento e loro uso |
| SE0400274D0 (sv) | 2004-02-09 | 2004-02-09 | Affibody Ab | New polypeptide |
| GB0518443D0 (en) | 2005-09-09 | 2005-10-19 | Evolutec Ltd | Method of treating myasthenia gravis |
| CA3022097C (en) | 2006-03-15 | 2020-10-27 | Alexion Pharmaceuticals, Inc. | Treatment of paroxysmal nocturnal hemoglobinuria patients by an inhibitor of complement |
| EP2190863B1 (en) | 2007-07-31 | 2015-09-02 | Affibody AB | New albumin binding compositions, methods and uses |
| ES2373832T3 (es) * | 2007-12-19 | 2012-02-09 | Affibody Ab | Polipéptido derivado de proteína a y capaz de unirse a pdgf. |
| US9187535B2 (en) | 2007-12-19 | 2015-11-17 | Affibody Ab | Polypeptide derived from protein A and able to bind PDGF |
| EP2072525A1 (en) | 2007-12-21 | 2009-06-24 | Affibody AB | New polypeptides having affinity for HER2 |
| PT2328616E (pt) | 2008-08-05 | 2015-08-26 | Novartis Ag | Composições e métodos para anticorpos dirigidos à proteína c5 do complemento |
| EP2327725A1 (en) | 2009-11-26 | 2011-06-01 | InflaRx GmbH | Anti-C5a binding moieties with high blocking activity |
| JP6276202B2 (ja) * | 2012-02-20 | 2018-02-07 | スウェディッシュ・オーファン・バイオヴィトラム・アーベー（ペーウーベーエル） | ヒト補体ｃ５に結合するポリペプチド |
| JP5980104B2 (ja) | 2012-11-22 | 2016-08-31 | 三菱電機株式会社 | 液晶表示装置の製造方法および液晶表示装置の製造システム |
| EP2935335B1 (en) | 2012-12-19 | 2020-10-28 | Affibody AB | New polypeptides |
| PT3038633T (pt) * | 2013-08-28 | 2021-01-14 | Ipc Res Llc | Polipéptidos estáveis que se ligam ao complemento humano c5 |
| JP7138411B2 (ja) * | 2013-08-28 | 2022-09-16 | アフィボディ・アーベー | 変異した骨格を有する結合ポリペプチド |
-
2014
- 2014-08-28 PT PT147658835T patent/PT3038633T/pt unknown
- 2014-08-28 DK DK14765883.5T patent/DK3038633T3/da active
- 2014-08-28 UA UAA201603124A patent/UA117933C2/uk unknown
- 2014-08-28 HR HRP20210013TT patent/HRP20210013T1/hr unknown
- 2014-08-28 EP EP20201264.7A patent/EP3811961B1/en active Active
- 2014-08-28 CN CN201480057470.XA patent/CN105658228B/zh active Active
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- 2014-08-28 RU RU2016111115A patent/RU2733897C2/ru active
- 2014-08-28 AU AU2014314222A patent/AU2014314222B2/en active Active
- 2014-08-28 JP JP2016537298A patent/JP6767865B2/ja active Active
- 2014-08-28 BR BR112016003142A patent/BR112016003142A2/pt not_active Application Discontinuation
- 2014-08-28 SI SI201431739T patent/SI3038633T1/sl unknown
- 2014-08-28 PL PL14765883T patent/PL3038633T3/pl unknown
- 2014-08-28 RU RU2020128977A patent/RU2020128977A/ru unknown
- 2014-08-28 EP EP14765883.5A patent/EP3038633B1/en active Active
- 2014-08-28 SM SM20210006T patent/SMT202100006T1/it unknown
- 2014-08-28 SG SG11201602679VA patent/SG11201602679VA/en unknown
- 2014-08-28 MY MYPI2016700583A patent/MY173804A/en unknown
- 2014-08-28 RS RS20210005A patent/RS61347B1/sr unknown
- 2014-08-28 KR KR1020167007498A patent/KR102446636B1/ko active Active
- 2014-08-28 WO PCT/EP2014/068282 patent/WO2015028558A1/en not_active Ceased
- 2014-08-28 US US14/914,290 patent/US9994626B2/en active Active
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- 2014-08-28 ES ES14765883T patent/ES2842105T3/es active Active
- 2014-08-28 NZ NZ718153A patent/NZ718153A/en unknown
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2016
- 2016-02-22 IL IL244218A patent/IL244218A/en active IP Right Grant
- 2016-02-24 PH PH12016500371A patent/PH12016500371B1/en unknown
- 2016-02-25 SA SA516370622A patent/SA516370622B1/ar unknown
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2020
- 2020-07-01 JP JP2020113725A patent/JP2020172505A/ja active Pending
- 2020-12-30 CY CY20201101229T patent/CY1123732T1/el unknown
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