SA516370622B1 - بولي ببتيدات ثابتة ترتبط بمكمل بشري c5 - Google Patents
بولي ببتيدات ثابتة ترتبط بمكمل بشري c5 Download PDFInfo
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- SA516370622B1 SA516370622B1 SA516370622A SA516370622A SA516370622B1 SA 516370622 B1 SA516370622 B1 SA 516370622B1 SA 516370622 A SA516370622 A SA 516370622A SA 516370622 A SA516370622 A SA 516370622A SA 516370622 B1 SA516370622 B1 SA 516370622B1
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| SE1350986 | 2013-08-28 | ||
| PCT/EP2014/068282 WO2015028558A1 (en) | 2013-08-28 | 2014-08-28 | Stable polypeptides binding to human complement c5 |
Publications (1)
| Publication Number | Publication Date |
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| SA516370622B1 true SA516370622B1 (ar) | 2018-12-23 |
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| SA516370622A SA516370622B1 (ar) | 2013-08-28 | 2016-02-25 | بولي ببتيدات ثابتة ترتبط بمكمل بشري c5 |
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Families Citing this family (8)
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| JP6276202B2 (ja) | 2012-02-20 | 2018-02-07 | スウェディッシュ・オーファン・バイオヴィトラム・アーベー（ペーウーベーエル） | ヒト補体ｃ５に結合するポリペプチド |
| PT3038633T (pt) * | 2013-08-28 | 2021-01-14 | Ipc Res Llc | Polipéptidos estáveis que se ligam ao complemento humano c5 |
| JP7138411B2 (ja) * | 2013-08-28 | 2022-09-16 | アフィボディ・アーベー | 変異した骨格を有する結合ポリペプチド |
| UY37651A (es) * | 2017-03-31 | 2018-10-31 | Swedish Orphan Biovitrum Ab Publ | Polipéptido de unión al il-1r-i |
| KR20250068795A (ko) | 2017-07-11 | 2025-05-16 | 알렉시온 파마슈티칼스, 인코포레이티드 | 보체 성분 c5 또는 혈청 알부민에 결합하는 폴리펩티드 및 그의 융합 단백질 |
| US20240124533A1 (en) * | 2021-02-15 | 2024-04-18 | Affibody Ab | New her2-binding polypeptide |
| MX2024005285A (es) * | 2021-11-01 | 2024-09-18 | Ipc Res Llc | Administracion de proteinas de union a c5. |
| WO2024227886A1 (en) | 2023-05-02 | 2024-11-07 | Mebrahtu Aman | Bispecific binding molecule |
Family Cites Families (23)
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| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US6074642A (en) | 1994-05-02 | 2000-06-13 | Alexion Pharmaceuticals, Inc. | Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis |
| CA2424379C (en) | 2000-10-10 | 2013-10-01 | Tanox, Inc. | Inhibition of complement c5 activation for the treatment and prevention of delayed xenograft or acute vascular rejection |
| AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| BRPI0211953B8 (pt) | 2001-08-17 | 2021-05-25 | Genentech Inc | anticorpo monoclonal ou fragmento de ligação a antígeno que se liga a c5 e c5a sem a prevenção da formação de c5b, linhagem celular, composição farmacêutica, bem como método in vitro para inibir a atividade de c5a e método de diagnóstico in vitro |
| ITMI20021527A1 (it) | 2002-07-11 | 2004-01-12 | Consiglio Nazionale Ricerche | Anticorpi anti componente c5 del complemento e loro uso |
| CA2579635A1 (en) * | 2003-09-10 | 2005-03-17 | Baxter International Inc. | Peptides that inhibit complement activation |
| SE0400274D0 (sv) | 2004-02-09 | 2004-02-09 | Affibody Ab | New polypeptide |
| GB0518443D0 (en) | 2005-09-09 | 2005-10-19 | Evolutec Ltd | Method of treating myasthenia gravis |
| SG172686A1 (en) * | 2006-03-08 | 2011-07-28 | Archemix Corp | Complement binding aptamers and anti-c5 agents useful in the treatment of ocular disorders |
| CA3022097C (en) | 2006-03-15 | 2020-10-27 | Alexion Pharmaceuticals, Inc. | Treatment of paroxysmal nocturnal hemoglobinuria patients by an inhibitor of complement |
| EP2190863B1 (en) | 2007-07-31 | 2015-09-02 | Affibody AB | New albumin binding compositions, methods and uses |
| ES2373832T3 (es) * | 2007-12-19 | 2012-02-09 | Affibody Ab | Polipéptido derivado de proteína a y capaz de unirse a pdgf. |
| US9187535B2 (en) | 2007-12-19 | 2015-11-17 | Affibody Ab | Polypeptide derived from protein A and able to bind PDGF |
| EP2072525A1 (en) | 2007-12-21 | 2009-06-24 | Affibody AB | New polypeptides having affinity for HER2 |
| PT2328616E (pt) | 2008-08-05 | 2015-08-26 | Novartis Ag | Composições e métodos para anticorpos dirigidos à proteína c5 do complemento |
| EP2327725A1 (en) | 2009-11-26 | 2011-06-01 | InflaRx GmbH | Anti-C5a binding moieties with high blocking activity |
| JP5827994B2 (ja) * | 2010-07-09 | 2015-12-02 | アフィボディ・アーベー | ポリペプチド |
| JP6276202B2 (ja) * | 2012-02-20 | 2018-02-07 | スウェディッシュ・オーファン・バイオヴィトラム・アーベー（ペーウーベーエル） | ヒト補体ｃ５に結合するポリペプチド |
| JP5980104B2 (ja) | 2012-11-22 | 2016-08-31 | 三菱電機株式会社 | 液晶表示装置の製造方法および液晶表示装置の製造システム |
| EP2935335B1 (en) | 2012-12-19 | 2020-10-28 | Affibody AB | New polypeptides |
| PT3038633T (pt) * | 2013-08-28 | 2021-01-14 | Ipc Res Llc | Polipéptidos estáveis que se ligam ao complemento humano c5 |
| JP7138411B2 (ja) * | 2013-08-28 | 2022-09-16 | アフィボディ・アーベー | 変異した骨格を有する結合ポリペプチド |
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