KR102446636B1 - 인간 보체 c5에 결합하는 안정한 폴리펩티드 - Google Patents
인간 보체 c5에 결합하는 안정한 폴리펩티드 Download PDFInfo
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- KR102446636B1 KR102446636B1 KR1020167007498A KR20167007498A KR102446636B1 KR 102446636 B1 KR102446636 B1 KR 102446636B1 KR 1020167007498 A KR1020167007498 A KR 1020167007498A KR 20167007498 A KR20167007498 A KR 20167007498A KR 102446636 B1 KR102446636 B1 KR 102446636B1
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
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- Transplantation (AREA)
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| SE1350986-4 | 2013-08-28 | ||
| SE1350986 | 2013-08-28 | ||
| PCT/EP2014/068282 WO2015028558A1 (en) | 2013-08-28 | 2014-08-28 | Stable polypeptides binding to human complement c5 |
Publications (2)
| Publication Number | Publication Date |
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| KR20160048121A KR20160048121A (ko) | 2016-05-03 |
| KR102446636B1 true KR102446636B1 (ko) | 2022-09-23 |
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| RS58503B1 (sr) | 2012-02-20 | 2019-04-30 | Swedish Orphan Biovitrum Ab Publ | Polipeptidi koji se vezuju za humani komplement c5 |
| MX367423B (es) * | 2013-08-28 | 2019-08-21 | Affibody Ab | Polipeptidos de union a c5. |
| LT3038633T (lt) * | 2013-08-28 | 2021-03-25 | Ipc Research, Llc | Stabilūs polipeptidai, kurie rišasi prie žmogaus komplemento c5 |
| UY37651A (es) * | 2017-03-31 | 2018-10-31 | Swedish Orphan Biovitrum Ab Publ | Polipéptido de unión al il-1r-i |
| CN117327188A (zh) | 2017-07-11 | 2024-01-02 | 亚力兄制药公司 | 结合补体成分c5或血清白蛋白的多肽及其融合蛋白 |
| WO2022171892A1 (en) * | 2021-02-15 | 2022-08-18 | Affibody Ab | New her2-binding polypeptide |
| KR20240134857A (ko) * | 2021-11-01 | 2024-09-10 | 아이피씨 리써치, 엘엘씨 | C5-결합 단백질 투여 |
| WO2024227886A1 (en) | 2023-05-02 | 2024-11-07 | Mebrahtu Aman | Bispecific binding molecule |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2003015819A1 (en) | 2001-08-17 | 2003-02-27 | Tanox, Inc. | Complement pathway inhibitors binding to c5 and c5a without preventing formation of c5b |
| WO2007028968A1 (en) | 2005-09-09 | 2007-03-15 | Evolutec Limited | Method of treating myasthenia gravis |
| WO2007106585A1 (en) | 2006-03-15 | 2007-09-20 | Alexion Pharmaceuticals, Inc. | Treatment of paroxysmal nocturnal hemoglobinuria patients by an inhibitor of complement |
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| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US6074642A (en) | 1994-05-02 | 2000-06-13 | Alexion Pharmaceuticals, Inc. | Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis |
| CA2424379C (en) | 2000-10-10 | 2013-10-01 | Tanox, Inc. | Inhibition of complement c5 activation for the treatment and prevention of delayed xenograft or acute vascular rejection |
| AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| ITMI20021527A1 (it) | 2002-07-11 | 2004-01-12 | Consiglio Nazionale Ricerche | Anticorpi anti componente c5 del complemento e loro uso |
| EP1667702A2 (en) | 2003-09-10 | 2006-06-14 | Baxter International Inc., Baxter Healthcare Corp. | Peptides that inhibit complement activation |
| SE0400274D0 (sv) * | 2004-02-09 | 2004-02-09 | Affibody Ab | New polypeptide |
| DK1991275T3 (en) * | 2006-03-08 | 2014-12-08 | Archemix Llc | Complement aptamers AND ANTI-C5 AGENTS FOR USE IN THE TREATMENT OF EYE DISEASES |
| US8937153B2 (en) | 2007-07-31 | 2015-01-20 | Affibody Ab | Compositions, methods and uses |
| DK2231860T3 (da) * | 2007-12-19 | 2011-12-05 | Affibody Ab | Polypeptid afledt protein A og i stand til at binde PDGF |
| US9187535B2 (en) | 2007-12-19 | 2015-11-17 | Affibody Ab | Polypeptide derived from protein A and able to bind PDGF |
| EP2072525A1 (en) | 2007-12-21 | 2009-06-24 | Affibody AB | New polypeptides having affinity for HER2 |
| MX2011001371A (es) | 2008-08-05 | 2011-06-16 | Novartis Ag | Composiciones y metodos para anticuerpos que se dirigen a la proteina de complementos c5. |
| EP2327725A1 (en) | 2009-11-26 | 2011-06-01 | InflaRx GmbH | Anti-C5a binding moieties with high blocking activity |
| WO2012004384A2 (en) | 2010-07-09 | 2012-01-12 | Affibody Ab | Polypeptides |
| RS58503B1 (sr) * | 2012-02-20 | 2019-04-30 | Swedish Orphan Biovitrum Ab Publ | Polipeptidi koji se vezuju za humani komplement c5 |
| JP5980104B2 (ja) | 2012-11-22 | 2016-08-31 | 三菱電機株式会社 | 液晶表示装置の製造方法および液晶表示装置の製造システム |
| EP2935335B1 (en) | 2012-12-19 | 2020-10-28 | Affibody AB | New polypeptides |
| MX367423B (es) * | 2013-08-28 | 2019-08-21 | Affibody Ab | Polipeptidos de union a c5. |
| LT3038633T (lt) * | 2013-08-28 | 2021-03-25 | Ipc Research, Llc | Stabilūs polipeptidai, kurie rišasi prie žmogaus komplemento c5 |
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2014
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2020
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- 2020-12-30 CY CY20201101229T patent/CY1123732T1/el unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003015819A1 (en) | 2001-08-17 | 2003-02-27 | Tanox, Inc. | Complement pathway inhibitors binding to c5 and c5a without preventing formation of c5b |
| WO2007028968A1 (en) | 2005-09-09 | 2007-03-15 | Evolutec Limited | Method of treating myasthenia gravis |
| WO2007106585A1 (en) | 2006-03-15 | 2007-09-20 | Alexion Pharmaceuticals, Inc. | Treatment of paroxysmal nocturnal hemoglobinuria patients by an inhibitor of complement |
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