SG11201602679VA - Stable polypeptides binding to human complement c5 - Google Patents

Stable polypeptides binding to human complement c5

Info

Publication number
SG11201602679VA
SG11201602679VA SG11201602679VA SG11201602679VA SG11201602679VA SG 11201602679V A SG11201602679V A SG 11201602679VA SG 11201602679V A SG11201602679V A SG 11201602679VA SG 11201602679V A SG11201602679V A SG 11201602679VA SG 11201602679V A SG11201602679V A SG 11201602679VA
Authority
SG
Singapore
Prior art keywords
human complement
polypeptides binding
stable polypeptides
stable
binding
Prior art date
Application number
SG11201602679VA
Inventor
Joakim Nilsson
Erik Nordling
Patrik Strömberg
Original Assignee
Swedish Orphan Biovitrum Ab Publ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Swedish Orphan Biovitrum Ab Publ filed Critical Swedish Orphan Biovitrum Ab Publ
Publication of SG11201602679VA publication Critical patent/SG11201602679VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
SG11201602679VA 2013-08-28 2014-08-28 Stable polypeptides binding to human complement c5 SG11201602679VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1350986 2013-08-28
PCT/EP2014/068282 WO2015028558A1 (en) 2013-08-28 2014-08-28 Stable polypeptides binding to human complement c5

Publications (1)

Publication Number Publication Date
SG11201602679VA true SG11201602679VA (en) 2016-05-30

Family

ID=51539238

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201602679VA SG11201602679VA (en) 2013-08-28 2014-08-28 Stable polypeptides binding to human complement c5

Country Status (29)

Country Link
US (1) US9994626B2 (en)
EP (2) EP3038633B1 (en)
JP (2) JP6767865B2 (en)
KR (1) KR102446636B1 (en)
CN (1) CN105658228B (en)
AU (1) AU2014314222B2 (en)
BR (2) BR112016003142A2 (en)
CA (1) CA2926976C (en)
CY (1) CY1123732T1 (en)
DK (1) DK3038633T3 (en)
ES (1) ES2842105T3 (en)
HK (1) HK1225656A1 (en)
HR (1) HRP20210013T1 (en)
HU (1) HUE052613T2 (en)
IL (1) IL244218A (en)
LT (1) LT3038633T (en)
MX (1) MX2016002397A (en)
MY (1) MY173804A (en)
NZ (1) NZ718153A (en)
PH (1) PH12016500371A1 (en)
PL (1) PL3038633T3 (en)
PT (1) PT3038633T (en)
RS (1) RS61347B1 (en)
RU (2) RU2020128977A (en)
SA (1) SA516370622B1 (en)
SG (1) SG11201602679VA (en)
SI (1) SI3038633T1 (en)
UA (1) UA117933C2 (en)
WO (1) WO2015028558A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201404942UA (en) 2012-02-20 2014-09-26 Swedish Orphan Biovitrum Ab Publ Polypeptides binding to human complement c5
SG11201602679VA (en) * 2013-08-28 2016-05-30 Swedish Orphan Biovitrum Ab Publ Stable polypeptides binding to human complement c5
RU2714156C2 (en) * 2013-08-28 2020-02-12 Аффибоди Аб C5-binding polypeptides
UY37651A (en) * 2017-03-31 2018-10-31 Swedish Orphan Biovitrum Ab Publ IL-1R-I UNION POLYPEPTIDE
CN117327188A (en) 2017-07-11 2024-01-02 亚力兄制药公司 Polypeptide binding complement component C5 or serum albumin and fusion protein thereof
WO2023077139A1 (en) * 2021-11-01 2023-05-04 Ipc Research, Llc Administration of c5-binding proteins

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE509359C2 (en) 1989-08-01 1999-01-18 Cemu Bioteknik Ab Use of stabilized protein or peptide conjugates for the preparation of a drug
US6074642A (en) 1994-05-02 2000-06-13 Alexion Pharmaceuticals, Inc. Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
DK1325033T3 (en) 2000-10-10 2010-04-06 Genentech Inc Inhibition of complement C5 activation for the treatment and prevention of delayed xenographic or acute vascular rejection
AT410798B (en) * 2001-01-26 2003-07-25 Cistem Biotechnologies Gmbh METHOD FOR IDENTIFYING, ISOLATING AND PRODUCING ANTIGENS AGAINST A SPECIFIC PATHOGEN
AU2002331601B2 (en) 2001-08-17 2006-04-13 Tanox, Inc. Complement pathway inhibitors binding to C5 and C5a without preventing the formation of C5b
ITMI20021527A1 (en) 2002-07-11 2004-01-12 Consiglio Nazionale Ricerche C5 COMPONENT ANTIBODIES OF COMPLEMENT AND THEIR USE
US7348401B2 (en) * 2003-09-10 2008-03-25 Innate Biotech, Inc. Peptides that inhibit complement activation
SE0400274D0 (en) * 2004-02-09 2004-02-09 Affibody Ab New polypeptide
GB0518443D0 (en) 2005-09-09 2005-10-19 Evolutec Ltd Method of treating myasthenia gravis
RU2477137C2 (en) * 2006-03-08 2013-03-10 АРКЕМИКС Эл Эл Си Complement-binding aptamers and c5 agents applicable for treating ocular disorders
PT2359834T (en) 2006-03-15 2016-12-23 Alexion Pharma Inc Treatment of paroxysmal nocturnal hemoglobinuria patients by an inhibitor of complement
WO2009016043A2 (en) 2007-07-31 2009-02-05 Affibody Ab New albumin binding compositions, methods and uses
EP2231860B1 (en) 2007-12-19 2011-10-05 Affibody AB Polypeptide derived from protein a and able to bind pdgf
US9187535B2 (en) 2007-12-19 2015-11-17 Affibody Ab Polypeptide derived from protein A and able to bind PDGF
EP2072525A1 (en) 2007-12-21 2009-06-24 Affibody AB New polypeptides having affinity for HER2
EP2815766B1 (en) 2008-08-05 2017-07-05 Novartis AG Compositions and methods for antibodies targeting complement protein C5
EP2327725A1 (en) 2009-11-26 2011-06-01 InflaRx GmbH Anti-C5a binding moieties with high blocking activity
MX2013000314A (en) * 2010-07-09 2013-01-29 Affibody Ab Polypeptides.
SG11201404942UA (en) * 2012-02-20 2014-09-26 Swedish Orphan Biovitrum Ab Publ Polypeptides binding to human complement c5
JP5980104B2 (en) 2012-11-22 2016-08-31 三菱電機株式会社 Liquid crystal display device manufacturing method and liquid crystal display device manufacturing system
WO2014096163A1 (en) 2012-12-19 2014-06-26 Affibody Ab New polypeptides
SG11201602679VA (en) * 2013-08-28 2016-05-30 Swedish Orphan Biovitrum Ab Publ Stable polypeptides binding to human complement c5
RU2714156C2 (en) * 2013-08-28 2020-02-12 Аффибоди Аб C5-binding polypeptides

Also Published As

Publication number Publication date
SA516370622B1 (en) 2018-12-23
EP3038633B1 (en) 2020-10-14
HUE052613T2 (en) 2021-05-28
MX2016002397A (en) 2016-09-08
CN105658228A (en) 2016-06-08
RU2020128977A (en) 2021-11-30
HRP20210013T1 (en) 2021-04-02
WO2015028558A1 (en) 2015-03-05
SI3038633T1 (en) 2021-05-31
PH12016500371B1 (en) 2016-05-02
UA117933C2 (en) 2018-10-25
CA2926976C (en) 2023-11-28
RU2016111115A3 (en) 2018-04-25
KR20160048121A (en) 2016-05-03
DK3038633T3 (en) 2021-01-11
PT3038633T (en) 2021-01-14
JP6767865B2 (en) 2020-10-14
CY1123732T1 (en) 2021-10-29
ES2842105T3 (en) 2021-07-12
RU2016111115A (en) 2017-10-03
EP3811961A1 (en) 2021-04-28
AU2014314222A1 (en) 2016-04-21
RU2733897C2 (en) 2020-10-09
CA2926976A1 (en) 2015-03-05
AU2014314222B2 (en) 2018-05-24
US9994626B2 (en) 2018-06-12
PL3038633T3 (en) 2021-07-19
PH12016500371A1 (en) 2016-05-02
MY173804A (en) 2020-02-24
CN105658228B (en) 2020-02-07
NZ718153A (en) 2022-05-27
JP2016529270A (en) 2016-09-23
EP3038633A1 (en) 2016-07-06
BR112016003142A2 (en) 2017-10-17
IL244218A0 (en) 2016-04-21
KR102446636B1 (en) 2022-09-23
LT3038633T (en) 2021-03-25
IL244218A (en) 2017-11-30
HK1225656A1 (en) 2017-09-15
BR122023020080A2 (en) 2023-12-26
RS61347B1 (en) 2021-02-26
JP2020172505A (en) 2020-10-22
US20160311870A1 (en) 2016-10-27

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