RU2571929C2 - Улучшенная очистка белка посредством модифицированного элюирования белка а - Google Patents

Улучшенная очистка белка посредством модифицированного элюирования белка а Download PDF

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Publication number
RU2571929C2
RU2571929C2 RU2012112536/10A RU2012112536A RU2571929C2 RU 2571929 C2 RU2571929 C2 RU 2571929C2 RU 2012112536/10 A RU2012112536/10 A RU 2012112536/10A RU 2012112536 A RU2012112536 A RU 2012112536A RU 2571929 C2 RU2571929 C2 RU 2571929C2
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polypeptide
protein
buffer
elution
gradient
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RU2012112536/10A
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English (en)
Russian (ru)
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RU2012112536A (ru
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Арик БРАУН
Кристофер Дж. ДАУД
Аша Нандини РАДХАМОХАН
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Дженентек, Инк.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2012112536/10A 2009-09-01 2010-09-01 Улучшенная очистка белка посредством модифицированного элюирования белка а RU2571929C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US23886709P 2009-09-01 2009-09-01
US61/238,867 2009-09-01
US25343809P 2009-10-20 2009-10-20
US61/253,438 2009-10-20
PCT/US2010/047448 WO2011028753A1 (en) 2009-09-01 2010-09-01 Enhanced protein purification through a modified protein a elution

Publications (2)

Publication Number Publication Date
RU2012112536A RU2012112536A (ru) 2013-10-10
RU2571929C2 true RU2571929C2 (ru) 2015-12-27

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RU2012112536/10A RU2571929C2 (ru) 2009-09-01 2010-09-01 Улучшенная очистка белка посредством модифицированного элюирования белка а

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US (3) US9428548B2 (enExample)
EP (2) EP2473617B1 (enExample)
JP (1) JP5787891B2 (enExample)
KR (1) KR101764449B1 (enExample)
CN (2) CN102686738A (enExample)
BR (1) BR112012004697B8 (enExample)
CA (1) CA2772653C (enExample)
ES (1) ES2787234T3 (enExample)
HR (1) HRP20200581T1 (enExample)
MX (1) MX2012002565A (enExample)
PL (1) PL2473617T3 (enExample)
RU (1) RU2571929C2 (enExample)
SI (1) SI2473617T1 (enExample)
WO (1) WO2011028753A1 (enExample)

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CA3167669A1 (en) * 2020-01-17 2021-07-22 Regeneron Pharmaceuticals, Inc. Hydrophobic interaction chromatography for viral clearance
KR20250011797A (ko) 2023-07-13 2025-01-22 주식회사 녹십자 알부민이 융합된 단백질의 정제방법

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Also Published As

Publication number Publication date
JP2013503877A (ja) 2013-02-04
HRP20200581T1 (hr) 2020-07-10
JP5787891B2 (ja) 2015-09-30
CN108409829A (zh) 2018-08-17
CA2772653C (en) 2019-06-25
BR112012004697B8 (pt) 2021-05-25
EP2473617A1 (en) 2012-07-11
BR112012004697B1 (pt) 2021-02-09
PL2473617T3 (pl) 2020-06-29
WO2011028753A1 (en) 2011-03-10
BR112012004697A2 (pt) 2015-09-08
EP3736338A1 (en) 2020-11-11
US20220081466A1 (en) 2022-03-17
US9428548B2 (en) 2016-08-30
US20220324905A1 (en) 2022-10-13
SI2473617T1 (sl) 2020-07-31
EP2473617A4 (en) 2014-04-09
ES2787234T3 (es) 2020-10-15
RU2012112536A (ru) 2013-10-10
CN102686738A (zh) 2012-09-19
US20130041139A1 (en) 2013-02-14
CA2772653A1 (en) 2011-03-10
EP2473617B1 (en) 2020-02-26
KR101764449B1 (ko) 2017-08-02
KR20120106719A (ko) 2012-09-26
MX2012002565A (es) 2012-05-29

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