RU2504542C2 - Гидроксилированные пиримидилциклопентаны в качестве ингибиторов протеинкиназы (акт) - Google Patents
Гидроксилированные пиримидилциклопентаны в качестве ингибиторов протеинкиназы (акт) Download PDFInfo
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- RU2504542C2 RU2504542C2 RU2010132911/04A RU2010132911A RU2504542C2 RU 2504542 C2 RU2504542 C2 RU 2504542C2 RU 2010132911/04 A RU2010132911/04 A RU 2010132911/04A RU 2010132911 A RU2010132911 A RU 2010132911A RU 2504542 C2 RU2504542 C2 RU 2504542C2
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Classifications
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- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Landscapes
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Rheumatology (AREA)
- Dermatology (AREA)
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- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2009208P | 2008-01-09 | 2008-01-09 | |
| US61/020,092 | 2008-01-09 | ||
| PCT/US2009/030610 WO2009089459A1 (en) | 2008-01-09 | 2009-01-09 | Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
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| RU2010132911A RU2010132911A (ru) | 2012-02-20 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2702355C1 (ru) * | 2013-11-15 | 2019-10-08 | Ф. Хоффманн-Ля Рош Аг | Способ получения пиримидинилциклопентановых соединений |
| RU2826179C2 (ru) * | 2013-11-15 | 2024-09-05 | Ф. Хоффманн-Ля Рош Аг | Способ получения пиримидинилциклопентановых соединений |
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| US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| CN101959887B (zh) | 2008-01-08 | 2013-07-31 | 阵列生物制药公司 | 作为激酶抑制剂的吡咯并吡啶 |
| CA2711782C (en) | 2008-01-09 | 2017-01-03 | Array Biopharma Inc. | 5h-cyclopenta[d]pyrimidines as akt protein kinase inhibitors |
| EP2242757B1 (en) | 2008-01-09 | 2012-08-01 | Array Biopharma, Inc. | Pyrazolopyridines as kinase inhibitors |
| DK2858989T3 (da) * | 2012-05-17 | 2020-06-02 | Genentech Inc | Amorf form af en AKT-hæmmende pyrimidinyl-cyclopentan-forbindelse, sammensætninger deraf og fremgangsmåder dertil |
| JP6214636B2 (ja) | 2012-05-17 | 2017-10-18 | アレイ バイオファーマ、インコーポレイテッド | ヒドロキシル化シクロペンチルピリミジン化合物を作製するためのプロセス |
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- 2009-01-09 CA CA2711699A patent/CA2711699A1/en not_active Withdrawn
- 2009-01-09 WO PCT/US2009/030610 patent/WO2009089459A1/en not_active Ceased
- 2009-01-09 NZ NZ586346A patent/NZ586346A/en not_active IP Right Cessation
- 2009-01-09 EP EP09700422.0A patent/EP2247578B1/en active Active
- 2009-01-09 AU AU2009204025A patent/AU2009204025B2/en not_active Ceased
- 2009-01-09 US US12/811,957 patent/US8835434B2/en active Active
- 2009-01-09 CN CN2009801019017A patent/CN101932564B/zh active Active
- 2009-01-09 RU RU2010132911/04A patent/RU2504542C2/ru active
- 2009-01-09 ES ES09700422T patent/ES2422733T3/es active Active
- 2009-01-09 KR KR1020107017605A patent/KR101624753B1/ko not_active Expired - Fee Related
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- 2010-07-06 ZA ZA2010/04769A patent/ZA201004769B/en unknown
- 2010-07-23 MA MA33047A patent/MA32183B1/fr unknown
- 2010-07-27 CR CR11601A patent/CR11601A/es not_active Application Discontinuation
- 2010-08-06 EC EC2010010389A patent/ECSP10010389A/es unknown
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| RU2702355C1 (ru) * | 2013-11-15 | 2019-10-08 | Ф. Хоффманн-Ля Рош Аг | Способ получения пиримидинилциклопентановых соединений |
| RU2826179C2 (ru) * | 2013-11-15 | 2024-09-05 | Ф. Хоффманн-Ля Рош Аг | Способ получения пиримидинилциклопентановых соединений |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5346345B2 (ja) | 2013-11-20 |
| AU2009204025A1 (en) | 2009-07-16 |
| NZ586346A (en) | 2012-02-24 |
| JP2011509308A (ja) | 2011-03-24 |
| KR20100118110A (ko) | 2010-11-04 |
| UA100545C2 (ru) | 2013-01-10 |
| RU2010132911A (ru) | 2012-02-20 |
| AU2009204025B2 (en) | 2014-02-20 |
| ES2422733T3 (es) | 2013-09-13 |
| ZA201004769B (en) | 2011-12-28 |
| US8835434B2 (en) | 2014-09-16 |
| CA2711699A1 (en) | 2009-07-16 |
| CR11601A (es) | 2010-08-19 |
| BRPI0906798A2 (pt) | 2015-07-14 |
| MA32183B1 (fr) | 2011-04-01 |
| WO2009089459A1 (en) | 2009-07-16 |
| KR101624753B1 (ko) | 2016-05-26 |
| US20110065716A1 (en) | 2011-03-17 |
| CN101932564A (zh) | 2010-12-29 |
| IL206575A0 (en) | 2010-12-30 |
| ECSP10010389A (es) | 2010-11-30 |
| EP2247578A1 (en) | 2010-11-10 |
| CN101932564B (zh) | 2012-12-26 |
| EP2247578B1 (en) | 2013-05-22 |
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