AU2009204025B2 - Hydroxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors - Google Patents
Hydroxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors Download PDFInfo
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- AU2009204025B2 AU2009204025B2 AU2009204025A AU2009204025A AU2009204025B2 AU 2009204025 B2 AU2009204025 B2 AU 2009204025B2 AU 2009204025 A AU2009204025 A AU 2009204025A AU 2009204025 A AU2009204025 A AU 2009204025A AU 2009204025 B2 AU2009204025 B2 AU 2009204025B2
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Classifications
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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Landscapes
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
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| US61/020,092 | 2008-01-09 | ||
| PCT/US2009/030610 WO2009089459A1 (en) | 2008-01-09 | 2009-01-09 | Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors |
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| AU2009204025A1 AU2009204025A1 (en) | 2009-07-16 |
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| US8846683B2 (en) | 2007-07-05 | 2014-09-30 | Array Biopharma, Inc. | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors |
| BRPI0813999A2 (pt) * | 2007-07-05 | 2019-10-01 | Array Biopharma Inc | ciclopentanos de pirimidil como inibidores de akt proteína cinase |
| US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
| JP5608097B2 (ja) | 2008-01-08 | 2014-10-15 | アレイ バイオファーマ、インコーポレイテッド | キナーゼ阻害薬としてのピロロピリジン |
| EP2250155B1 (en) | 2008-01-09 | 2013-07-03 | Array Biopharma, Inc. | 5h-cyclopenta[d]pyrimidines as akt protein kinase inhibitors |
| US8372842B2 (en) | 2008-01-09 | 2013-02-12 | Array Biopharma Inc. | Pyrazolopyridines as kinase inhibitors |
| RS60417B9 (sr) * | 2012-05-17 | 2021-07-30 | Genentech Inc | Amorfni oblik aktivnog jedinjenja koje inhibira pirimidinil-ciklopentansko jedinjenje, smeše i njegove metode |
| ES2588878T3 (es) * | 2012-05-17 | 2016-11-07 | Array Biopharma, Inc. | Proceso para preparar compuestos de ciclopentilpirimidina hidroxilada |
| CN105899492B (zh) * | 2013-11-15 | 2021-08-24 | 豪夫迈·罗氏有限公司 | 用于制备嘧啶基环戊烷化合物的方法 |
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| US3885035A (en) * | 1972-04-05 | 1975-05-20 | Sandoz Ag | Method for treating arrhythmia by using 1,4-bis(4 quinazolinyl) piperazines |
| US3956495A (en) * | 1973-10-30 | 1976-05-11 | Eli Lilly And Company | 2,4-Diaminoquinazolines as antithrombotic agents |
| US3966936A (en) * | 1974-02-21 | 1976-06-29 | Pfizer Inc. | Piperazino quinazoline bronchodilators |
| US4060615A (en) * | 1976-02-18 | 1977-11-29 | Mead Johnson & Company | 2-Piperazinyl-6,7-dimethoxyquinazolines |
| JPS562968A (en) * | 1979-06-21 | 1981-01-13 | Mitsubishi Yuka Yakuhin Kk | Novel pyrimidine derivative |
| JPS6270A (ja) | 1985-03-07 | 1987-01-06 | Sankyo Co Ltd | シクロペンタ〔ｄ〕ピリミジン誘導体 |
| WO1990007926A1 (en) * | 1989-01-20 | 1990-07-26 | Pfizer Inc. | 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines |
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| ATE311363T1 (de) * | 1999-01-13 | 2005-12-15 | Warner Lambert Co | Sulfohydroxamsäure and sulfohydroxamate und ihre verwendung als mek-inhibitoren |
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- 2009-01-09 AU AU2009204025A patent/AU2009204025B2/en not_active Ceased
- 2009-01-09 WO PCT/US2009/030610 patent/WO2009089459A1/en not_active Ceased
- 2009-01-09 CA CA2711699A patent/CA2711699A1/en not_active Withdrawn
- 2009-01-09 NZ NZ586346A patent/NZ586346A/en not_active IP Right Cessation
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| WO2005051304A2 (en) * | 2003-11-21 | 2005-06-09 | Array Biopharma Inc. | Akt protein kinase inhibitors |
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| ZA201004769B (en) | 2011-12-28 |
| EP2247578A1 (en) | 2010-11-10 |
| IL206575A0 (en) | 2010-12-30 |
| EP2247578B1 (en) | 2013-05-22 |
| CN101932564A (zh) | 2010-12-29 |
| ECSP10010389A (es) | 2010-11-30 |
| JP2011509308A (ja) | 2011-03-24 |
| RU2504542C2 (ru) | 2014-01-20 |
| US20110065716A1 (en) | 2011-03-17 |
| KR101624753B1 (ko) | 2016-05-26 |
| CA2711699A1 (en) | 2009-07-16 |
| JP5346345B2 (ja) | 2013-11-20 |
| ES2422733T3 (es) | 2013-09-13 |
| US8835434B2 (en) | 2014-09-16 |
| AU2009204025A1 (en) | 2009-07-16 |
| RU2010132911A (ru) | 2012-02-20 |
| BRPI0906798A2 (pt) | 2015-07-14 |
| NZ586346A (en) | 2012-02-24 |
| CN101932564B (zh) | 2012-12-26 |
| WO2009089459A1 (en) | 2009-07-16 |
| UA100545C2 (ru) | 2013-01-10 |
| CR11601A (es) | 2010-08-19 |
| MA32183B1 (fr) | 2011-04-01 |
| KR20100118110A (ko) | 2010-11-04 |
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