RU2488396C2 - Тонкие гранулы, имеющие улучшенные характеристики в водной суспензии - Google Patents

Тонкие гранулы, имеющие улучшенные характеристики в водной суспензии Download PDF

Info

Publication number
RU2488396C2
RU2488396C2 RU2010145148/15A RU2010145148A RU2488396C2 RU 2488396 C2 RU2488396 C2 RU 2488396C2 RU 2010145148/15 A RU2010145148/15 A RU 2010145148/15A RU 2010145148 A RU2010145148 A RU 2010145148A RU 2488396 C2 RU2488396 C2 RU 2488396C2
Authority
RU
Russia
Prior art keywords
surfactant
fine granules
granules
amount
thin
Prior art date
Application number
RU2010145148/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2010145148A (ru
Inventor
Казуаки ЙОСИОКА
Макото НОАМИ
Риудзи ТОМОСИГЕ
Original Assignee
Сионоги Энд Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сионоги Энд Ко., Лтд. filed Critical Сионоги Энд Ко., Лтд.
Publication of RU2010145148A publication Critical patent/RU2010145148A/ru
Application granted granted Critical
Publication of RU2488396C2 publication Critical patent/RU2488396C2/ru

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
RU2010145148/15A 2008-04-04 2009-04-03 Тонкие гранулы, имеющие улучшенные характеристики в водной суспензии RU2488396C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008-098204 2008-04-04
JP2008098204A JP2011153075A (ja) 2008-04-04 2008-04-04 水懸濁性を向上させた細粒剤
PCT/JP2009/056942 WO2009123304A1 (ja) 2008-04-04 2009-04-03 水懸濁性を向上させた細粒剤

Publications (2)

Publication Number Publication Date
RU2010145148A RU2010145148A (ru) 2012-05-20
RU2488396C2 true RU2488396C2 (ru) 2013-07-27

Family

ID=41135667

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2010145148/15A RU2488396C2 (ru) 2008-04-04 2009-04-03 Тонкие гранулы, имеющие улучшенные характеристики в водной суспензии

Country Status (6)

Country Link
JP (1) JP2011153075A (ja)
KR (1) KR101343283B1 (ja)
CN (1) CN102056610B (ja)
RU (1) RU2488396C2 (ja)
TW (1) TWI426913B (ja)
WO (1) WO2009123304A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101756906B (zh) * 2009-11-02 2011-11-16 严洁 盐酸头孢卡品酯颗粒的药物组合物及其制备方法
JP6192919B2 (ja) 2012-11-02 2017-09-06 Ntn株式会社 インホイールモータ駆動装置
WO2015152190A1 (ja) * 2014-03-31 2015-10-08 富山化学工業株式会社 セファロスポリンエステルを含む粒状固形製剤およびその製造方法
WO2020170025A1 (en) 2019-02-22 2020-08-27 Daikin Industries, Ltd. Laminate
CN110974803B (zh) * 2019-12-31 2022-03-11 山东罗欣药业集团股份有限公司 一种盐酸头孢卡品酯颗粒剂及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2281757C2 (ru) * 2000-09-19 2006-08-20 Дайити Фармасьютикал Ко., Лтд. Фармацевтическая композиция

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07242568A (ja) * 1994-03-04 1995-09-19 Eisai Co Ltd 苦味隠蔽製剤
CN100528233C (zh) * 2003-10-29 2009-08-19 盐野义制药株式会社 不愉快味道改善了的包覆制剂的制造方法
JP4945108B2 (ja) * 2004-09-24 2012-06-06 興和株式会社 イソソルビド製剤
JP2007211006A (ja) * 2006-01-16 2007-08-23 Ono Pharmaceut Co Ltd 溶出安定性を有するコーティング固形製剤
JP2007197375A (ja) * 2006-01-27 2007-08-09 Pfizer Japan Inc アジスロマイシン類を有効成分とする帯電防止作用を有する組成物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2281757C2 (ru) * 2000-09-19 2006-08-20 Дайити Фармасьютикал Ко., Лтд. Фармацевтическая композиция

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ТЕХНОЛОГИЯ ЛЕКАРСТВЕННЫХ ФОРМ /Под ред. Ивановой Л.А. - М.: Медицина, 1991, с.139-141. *

Also Published As

Publication number Publication date
KR101343283B1 (ko) 2013-12-18
TW201004625A (en) 2010-02-01
WO2009123304A1 (ja) 2009-10-08
JP2011153075A (ja) 2011-08-11
RU2010145148A (ru) 2012-05-20
TWI426913B (zh) 2014-02-21
KR20110003357A (ko) 2011-01-11
CN102056610A (zh) 2011-05-11
CN102056610B (zh) 2013-07-17

Similar Documents

Publication Publication Date Title
JP5604304B2 (ja) 口腔内崩壊性固形製剤
JP5053865B2 (ja) 口腔内崩壊性固形製剤の製造法
JP4739340B2 (ja) 口腔内速崩壊性錠
AU2005324132A1 (en) Solid, orally applicable pharmaceutical administration forms containing rivaroxaban having modified release
JP4748839B2 (ja) シロスタゾール製剤
JP2011063611A (ja) シロスタゾール製剤
KR19980702830A (ko) 양성자 펌프 억제제를 함유하는 다수 단위 발포성 제형
RU2488396C2 (ru) Тонкие гранулы, имеющие улучшенные характеристики в водной суспензии
CN102548542A (zh) 含有两种以上粒子的口腔速崩片
US8753682B2 (en) Dual release oral tablet compositions of dexlansoprazole
KR20130041144A (ko) 데페라시록스의 경구투여용 제제
JP2010519200A (ja) シロスタゾールを含む制御放出製剤及びその製造方法
JP2011246428A (ja) 口腔内崩壊型医薬品及びその製造方法
CA2400565A1 (en) Biomodulated multiparticulate formulations
JP4336380B1 (ja) 水懸濁性を向上させた細粒剤
KR20080080318A (ko) 지용성 약물을 함유하는 구강내 속붕정
JP3981134B2 (ja) 不快味を改善した被覆製剤の製造方法
EP2046337B1 (en) Solid forms containing meloxicam with improved buccal taste and process for their preparation
JPH08310969A (ja) 固形薬品組成物及びその製造方法
AU611740B2 (en) Pharmaceutical composition and process for its preparation
JP2006507298A (ja) 経口持続放出型錠剤、ならびにその製造法および使用法
KR20140076998A (ko) 에스오메프라졸 유리염기 또는 그의 알칼리염을 포함하는 고미가 차폐된 약학 제제 및 이의 제조방법
KR102363727B1 (ko) 생체이용률이 개선된 프란루카스트 함유 고형 제제의 조성물 및 그 제조방법
JP7394302B2 (ja) ソリフェナシンの苦味がマスキングされた粒子状医薬組成物
RU2397767C2 (ru) Стабильная, состоящая из частиц фармацевтическая композиция, содержащая солифенацин или его соль

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20180404