RU2284328C2 - Кристаллы производных таксана и способ их получения - Google Patents

Кристаллы производных таксана и способ их получения Download PDF

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Publication number
RU2284328C2
RU2284328C2 RU2004119547/04A RU2004119547A RU2284328C2 RU 2284328 C2 RU2284328 C2 RU 2284328C2 RU 2004119547/04 A RU2004119547/04 A RU 2004119547/04A RU 2004119547 A RU2004119547 A RU 2004119547A RU 2284328 C2 RU2284328 C2 RU 2284328C2
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RU
Russia
Prior art keywords
crystals
mixture
water
solvent
acetone
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RU2004119547/04A
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English (en)
Russian (ru)
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RU2004119547A (ru
Inventor
Сейсиро УТИДА (JP)
Сейсиро УТИДА
Есихиро ТАКАЯНАГИ (JP)
Есихиро ТАКАЯНАГИ
Макото ОНО (JP)
Макото Оно
Original Assignee
Дайити Фармасьютикал Ко., Лтд.
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Application filed by Дайити Фармасьютикал Ко., Лтд. filed Critical Дайити Фармасьютикал Ко., Лтд.
Publication of RU2004119547A publication Critical patent/RU2004119547A/ru
Application granted granted Critical
Publication of RU2284328C2 publication Critical patent/RU2284328C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2004119547/04A 2001-11-29 2002-11-29 Кристаллы производных таксана и способ их получения RU2284328C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001-363681 2001-11-29
JP2001363681 2001-11-29

Publications (2)

Publication Number Publication Date
RU2004119547A RU2004119547A (ru) 2005-03-27
RU2284328C2 true RU2284328C2 (ru) 2006-09-27

Family

ID=19173983

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004119547/04A RU2284328C2 (ru) 2001-11-29 2002-11-29 Кристаллы производных таксана и способ их получения

Country Status (18)

Country Link
US (1) US7410980B2 (fr)
EP (1) EP1457492B1 (fr)
JP (1) JP4310191B2 (fr)
KR (1) KR100886805B1 (fr)
CN (1) CN1295229C (fr)
AT (1) ATE382624T1 (fr)
AU (1) AU2002354126A1 (fr)
CA (1) CA2468953C (fr)
DE (1) DE60224440T2 (fr)
DK (1) DK1457492T3 (fr)
ES (1) ES2299612T3 (fr)
HK (1) HK1065547A1 (fr)
MX (1) MXPA04005192A (fr)
NO (1) NO328559B1 (fr)
PT (1) PT1457492E (fr)
RU (1) RU2284328C2 (fr)
TW (1) TWI333856B (fr)
WO (1) WO2003045953A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2546661C2 (ru) * 2010-10-29 2015-04-10 Индена С.П.А. Кристаллическая форма 13-[(n-трет-бутоксикарбонил)-2'-о-гексаноил-3-фенилизосеринил]-10-диацетилбаккатина iii

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
ES2371947T3 (es) 2004-04-30 2012-01-11 Daiichi Sankyo Company, Limited Proceso para producir taxano pentacíclico.
WO2007005829A2 (fr) * 2005-07-01 2007-01-11 Nec Laboratories America, Inc. Compression memoire basee sur un systeme d'exploitation pour systemes integres
US8785669B2 (en) 2010-06-30 2014-07-22 Gfv, Llc Taxane compounds, compositions and methods
US8697892B2 (en) 2010-06-30 2014-04-15 Gfv, Llc Taxane compounds, compositions and methods
JP5909089B2 (ja) * 2011-02-01 2016-04-26 アークレイ株式会社 光学結晶、テラヘルツ波発生装置及び方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1094940C (zh) * 1995-04-28 2002-11-27 第一制药株式会社 具有抗肿瘤活性的紫杉酚衍生物
JP2000159757A (ja) * 1998-12-01 2000-06-13 Dai Ichi Seiyaku Co Ltd ７−デオキシタキソール誘導体の製造方法
AU761389B2 (en) * 1999-05-17 2003-06-05 Bristol-Myers Squibb Company Novel reaction conditions for the cleavage of silyl ethers in the preparation of paclitaxel (taxol) and paclitaxel analogues
PT1221445E (pt) * 1999-10-15 2008-10-08 Daiichi Sankyo Co Ltd Compostos pentacíclicos derivados de taxamos
US6677456B2 (en) 1999-10-15 2004-01-13 Daiichi Pharmaceutical Co., Ltd. Pentacyclic taxan compound
WO2002070512A1 (fr) * 2001-03-07 2002-09-12 Daiichi Pharmaceutical Co, Ltd. Procede de fabrication d'un derive d'azetidinone-2

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2546661C2 (ru) * 2010-10-29 2015-04-10 Индена С.П.А. Кристаллическая форма 13-[(n-трет-бутоксикарбонил)-2'-о-гексаноил-3-фенилизосеринил]-10-диацетилбаккатина iii
US9062018B2 (en) 2010-10-29 2015-06-23 Indena S.P.A Crytalline form of 13-[(N-tert-butoxycarbonyl)-2′-O-hexanoyl-3-phenylisoserinyl]-10-deacetylbaccatin III

Also Published As

Publication number Publication date
CA2468953C (fr) 2010-05-11
DE60224440D1 (de) 2008-02-14
AU2002354126A1 (en) 2003-06-10
EP1457492B1 (fr) 2008-01-02
KR20040081426A (ko) 2004-09-21
DE60224440T2 (de) 2009-01-02
ES2299612T3 (es) 2008-06-01
CA2468953A1 (fr) 2003-06-05
EP1457492A1 (fr) 2004-09-15
PT1457492E (pt) 2008-02-28
CN1295229C (zh) 2007-01-17
NO20042723L (no) 2004-06-28
WO2003045953A1 (fr) 2003-06-05
EP1457492A4 (fr) 2005-03-23
RU2004119547A (ru) 2005-03-27
US20050070579A1 (en) 2005-03-31
JP4310191B2 (ja) 2009-08-05
JPWO2003045953A1 (ja) 2005-04-07
US7410980B2 (en) 2008-08-12
TW200301114A (en) 2003-07-01
CN1596259A (zh) 2005-03-16
ATE382624T1 (de) 2008-01-15
MXPA04005192A (es) 2005-02-22
NO328559B1 (no) 2010-03-22
KR100886805B1 (ko) 2009-03-05
HK1065547A1 (en) 2005-02-25
TWI333856B (en) 2010-12-01
DK1457492T3 (da) 2008-05-13

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20151130

NF4A Reinstatement of patent

Effective date: 20171023