DE60224440D1 - Kristalle von taxanderivaten und verfahren zu deren herstellung - Google Patents

Kristalle von taxanderivaten und verfahren zu deren herstellung

Info

Publication number
DE60224440D1
DE60224440D1 DE60224440T DE60224440T DE60224440D1 DE 60224440 D1 DE60224440 D1 DE 60224440D1 DE 60224440 T DE60224440 T DE 60224440T DE 60224440 T DE60224440 T DE 60224440T DE 60224440 D1 DE60224440 D1 DE 60224440D1
Authority
DE
Germany
Prior art keywords
mixture
taxanderivates
crystals
production
organic solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60224440T
Other languages
English (en)
Other versions
DE60224440T2 (de
Inventor
S Uchida
Y Takayanagi
Makoto Ono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Application granted granted Critical
Publication of DE60224440D1 publication Critical patent/DE60224440D1/de
Publication of DE60224440T2 publication Critical patent/DE60224440T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
DE60224440T 2001-11-29 2002-11-29 Kristalle von taxanderivaten und verfahren zu deren herstellung Expired - Lifetime DE60224440T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001363681 2001-11-29
JP2001363681 2001-11-29
PCT/JP2002/012506 WO2003045953A1 (fr) 2001-11-29 2002-11-29 Cristaux de derive de taxane et procede de production associe

Publications (2)

Publication Number Publication Date
DE60224440D1 true DE60224440D1 (de) 2008-02-14
DE60224440T2 DE60224440T2 (de) 2009-01-02

Family

ID=19173983

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60224440T Expired - Lifetime DE60224440T2 (de) 2001-11-29 2002-11-29 Kristalle von taxanderivaten und verfahren zu deren herstellung

Country Status (18)

Country Link
US (1) US7410980B2 (de)
EP (1) EP1457492B1 (de)
JP (1) JP4310191B2 (de)
KR (1) KR100886805B1 (de)
CN (1) CN1295229C (de)
AT (1) ATE382624T1 (de)
AU (1) AU2002354126A1 (de)
CA (1) CA2468953C (de)
DE (1) DE60224440T2 (de)
DK (1) DK1457492T3 (de)
ES (1) ES2299612T3 (de)
HK (1) HK1065547A1 (de)
MX (1) MXPA04005192A (de)
NO (1) NO328559B1 (de)
PT (1) PT1457492E (de)
RU (1) RU2284328C2 (de)
TW (1) TWI333856B (de)
WO (1) WO2003045953A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
DK1741716T3 (da) 2004-04-30 2011-11-28 Daiichi Sankyo Co Ltd Fremgangsmåde til fremstilling af pentacyklisk taxan
US20070005911A1 (en) * 2005-07-01 2007-01-04 Nec Laboratories America, Inc. Operating System-Based Memory Compression for Embedded Systems
US8785669B2 (en) 2010-06-30 2014-07-22 Gfv, Llc Taxane compounds, compositions and methods
US8697892B2 (en) 2010-06-30 2014-04-15 Gfv, Llc Taxane compounds, compositions and methods
EP2447268A1 (de) 2010-10-29 2012-05-02 INDENA S.p.A. Kristalline Form von 13-[(N-tert-butoxycarbonyl)-2'-O-hexanoyl-3-phenylisoserinyl]-10-deacetylbaccatin III
JP5909089B2 (ja) * 2011-02-01 2016-04-26 アークレイ株式会社 光学結晶、テラヘルツ波発生装置及び方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2164241T3 (es) 1995-04-28 2002-02-16 Daiichi Seiyaku Co Compuestos pentaciclicos.
JP2000159757A (ja) * 1998-12-01 2000-06-13 Dai Ichi Seiyaku Co Ltd ７−デオキシタキソール誘導体の製造方法
DK1178979T3 (da) * 1999-05-17 2004-03-22 Bristol Myers Squibb Co Hidtil ukendte reaktionsbetingelser til spaltning af silylethere ved fremstillingen af paclitaxel (Taxol(R)) og paclitaxelanaloge
MXPA02003797A (es) 1999-10-15 2002-12-13 Daiichi Seiyaku Co Compuestos de taxano pentaciclico.
US6677456B2 (en) 1999-10-15 2004-01-13 Daiichi Pharmaceutical Co., Ltd. Pentacyclic taxan compound
JP4142444B2 (ja) * 2001-03-07 2008-09-03 第一三共株式会社 ２−アゼチジノン誘導体の製造方法

Also Published As

Publication number Publication date
PT1457492E (pt) 2008-02-28
ES2299612T3 (es) 2008-06-01
KR100886805B1 (ko) 2009-03-05
DK1457492T3 (da) 2008-05-13
JP4310191B2 (ja) 2009-08-05
NO328559B1 (no) 2010-03-22
HK1065547A1 (en) 2005-02-25
CN1596259A (zh) 2005-03-16
US20050070579A1 (en) 2005-03-31
EP1457492A1 (de) 2004-09-15
RU2004119547A (ru) 2005-03-27
RU2284328C2 (ru) 2006-09-27
JPWO2003045953A1 (ja) 2005-04-07
WO2003045953A1 (fr) 2003-06-05
CA2468953A1 (en) 2003-06-05
ATE382624T1 (de) 2008-01-15
CA2468953C (en) 2010-05-11
NO20042723L (no) 2004-06-28
DE60224440T2 (de) 2009-01-02
KR20040081426A (ko) 2004-09-21
US7410980B2 (en) 2008-08-12
EP1457492A4 (de) 2005-03-23
CN1295229C (zh) 2007-01-17
TWI333856B (en) 2010-12-01
TW200301114A (en) 2003-07-01
EP1457492B1 (de) 2008-01-02
MXPA04005192A (es) 2005-02-22
AU2002354126A1 (en) 2003-06-10

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Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: UCHIDA, S., EDOGAWA-KU, TOKYO 134-8630, JP

Inventor name: TAKAYANAGI, Y., EDOGAWA-KU, TOKYO 134-8630, JP

Inventor name: ONO, MAKOTO, EDOGAWA-KU, TOKYO 134-8630, JP

8364 No opposition during term of opposition