DE60224440D1 - Kristalle von taxanderivaten und verfahren zu deren herstellung - Google Patents

Kristalle von taxanderivaten und verfahren zu deren herstellung

Info

Publication number
DE60224440D1
DE60224440D1 DE60224440T DE60224440T DE60224440D1 DE 60224440 D1 DE60224440 D1 DE 60224440D1 DE 60224440 T DE60224440 T DE 60224440T DE 60224440 T DE60224440 T DE 60224440T DE 60224440 D1 DE60224440 D1 DE 60224440D1
Authority
DE
Germany
Prior art keywords
mixture
taxanderivates
crystals
production
organic solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60224440T
Other languages
English (en)
Other versions
DE60224440T2 (de
Inventor
S Uchida
Y Takayanagi
Makoto Ono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Sankyo Co Ltd
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of DE60224440D1 publication Critical patent/DE60224440D1/de
Application granted granted Critical
Publication of DE60224440T2 publication Critical patent/DE60224440T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60224440T 2001-11-29 2002-11-29 Kristalle von taxanderivaten und verfahren zu deren herstellung Expired - Lifetime DE60224440T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001363681 2001-11-29
JP2001363681 2001-11-29
PCT/JP2002/012506 WO2003045953A1 (fr) 2001-11-29 2002-11-29 Cristaux de derive de taxane et procede de production associe

Publications (2)

Publication Number Publication Date
DE60224440D1 true DE60224440D1 (de) 2008-02-14
DE60224440T2 DE60224440T2 (de) 2009-01-02

Family

ID=19173983

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60224440T Expired - Lifetime DE60224440T2 (de) 2001-11-29 2002-11-29 Kristalle von taxanderivaten und verfahren zu deren herstellung

Country Status (18)

Country Link
US (1) US7410980B2 (de)
EP (1) EP1457492B1 (de)
JP (1) JP4310191B2 (de)
KR (1) KR100886805B1 (de)
CN (1) CN1295229C (de)
AT (1) ATE382624T1 (de)
AU (1) AU2002354126A1 (de)
CA (1) CA2468953C (de)
DE (1) DE60224440T2 (de)
DK (1) DK1457492T3 (de)
ES (1) ES2299612T3 (de)
HK (1) HK1065547A1 (de)
MX (1) MXPA04005192A (de)
NO (1) NO328559B1 (de)
PT (1) PT1457492E (de)
RU (1) RU2284328C2 (de)
TW (1) TWI333856B (de)
WO (1) WO2003045953A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
ES2371947T3 (es) 2004-04-30 2012-01-11 Daiichi Sankyo Company, Limited Proceso para producir taxano pentacíclico.
WO2007005829A2 (en) * 2005-07-01 2007-01-11 Nec Laboratories America, Inc. Operating system-based memory compression for embedded systems
US8785669B2 (en) 2010-06-30 2014-07-22 Gfv, Llc Taxane compounds, compositions and methods
US8697892B2 (en) 2010-06-30 2014-04-15 Gfv, Llc Taxane compounds, compositions and methods
EP2447268A1 (de) 2010-10-29 2012-05-02 INDENA S.p.A. Kristalline Form von 13-[(N-tert-butoxycarbonyl)-2'-O-hexanoyl-3-phenylisoserinyl]-10-deacetylbaccatin III
JP5909089B2 (ja) * 2011-02-01 2016-04-26 アークレイ株式会社 光学結晶、テラヘルツ波発生装置及び方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1094940C (zh) * 1995-04-28 2002-11-27 第一制药株式会社 具有抗肿瘤活性的紫杉酚衍生物
JP2000159757A (ja) * 1998-12-01 2000-06-13 Dai Ichi Seiyaku Co Ltd ７−デオキシタキソール誘導体の製造方法
AU761389B2 (en) * 1999-05-17 2003-06-05 Bristol-Myers Squibb Company Novel reaction conditions for the cleavage of silyl ethers in the preparation of paclitaxel (taxol) and paclitaxel analogues
PT1221445E (pt) * 1999-10-15 2008-10-08 Daiichi Sankyo Co Ltd Compostos pentacíclicos derivados de taxamos
US6677456B2 (en) 1999-10-15 2004-01-13 Daiichi Pharmaceutical Co., Ltd. Pentacyclic taxan compound
WO2002070512A1 (fr) * 2001-03-07 2002-09-12 Daiichi Pharmaceutical Co, Ltd. Procede de fabrication d'un derive d'azetidinone-2

Also Published As

Publication number Publication date
CA2468953C (en) 2010-05-11
AU2002354126A1 (en) 2003-06-10
EP1457492B1 (de) 2008-01-02
KR20040081426A (ko) 2004-09-21
DE60224440T2 (de) 2009-01-02
ES2299612T3 (es) 2008-06-01
CA2468953A1 (en) 2003-06-05
EP1457492A1 (de) 2004-09-15
PT1457492E (pt) 2008-02-28
CN1295229C (zh) 2007-01-17
NO20042723L (no) 2004-06-28
WO2003045953A1 (fr) 2003-06-05
EP1457492A4 (de) 2005-03-23
RU2004119547A (ru) 2005-03-27
US20050070579A1 (en) 2005-03-31
JP4310191B2 (ja) 2009-08-05
JPWO2003045953A1 (ja) 2005-04-07
US7410980B2 (en) 2008-08-12
TW200301114A (en) 2003-07-01
CN1596259A (zh) 2005-03-16
ATE382624T1 (de) 2008-01-15
MXPA04005192A (es) 2005-02-22
NO328559B1 (no) 2010-03-22
KR100886805B1 (ko) 2009-03-05
HK1065547A1 (en) 2005-02-25
RU2284328C2 (ru) 2006-09-27
TWI333856B (en) 2010-12-01
DK1457492T3 (da) 2008-05-13

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Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: UCHIDA, S., EDOGAWA-KU, TOKYO 134-8630, JP

Inventor name: TAKAYANAGI, Y., EDOGAWA-KU, TOKYO 134-8630, JP

Inventor name: ONO, MAKOTO, EDOGAWA-KU, TOKYO 134-8630, JP

8364 No opposition during term of opposition