DK1741716T3 - Fremgangsmåde til fremstilling af pentacyklisk taxan - Google Patents
Fremgangsmåde til fremstilling af pentacyklisk taxanInfo
- Publication number
- DK1741716T3 DK1741716T3 DK05737233.6T DK05737233T DK1741716T3 DK 1741716 T3 DK1741716 T3 DK 1741716T3 DK 05737233 T DK05737233 T DK 05737233T DK 1741716 T3 DK1741716 T3 DK 1741716T3
- Authority
- DK
- Denmark
- Prior art keywords
- group
- oral
- preparation
- compound
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004136359 | 2004-04-30 | ||
| PCT/JP2005/008034 WO2005105807A1 (ja) | 2004-04-30 | 2005-04-27 | 五環性タキサンの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1741716T3 true DK1741716T3 (da) | 2011-11-28 |
Family
ID=35241616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05737233.6T DK1741716T3 (da) | 2004-04-30 | 2005-04-27 | Fremgangsmåde til fremstilling af pentacyklisk taxan |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7456302B2 (da) |
| EP (1) | EP1741716B8 (da) |
| JP (1) | JP4800205B2 (da) |
| KR (1) | KR101186475B1 (da) |
| CN (1) | CN1942473B (da) |
| AT (1) | ATE526332T1 (da) |
| CA (1) | CA2565013C (da) |
| DK (1) | DK1741716T3 (da) |
| ES (1) | ES2371947T3 (da) |
| HK (1) | HK1094582A1 (da) |
| IL (1) | IL178918A (da) |
| MX (1) | MXPA06012588A (da) |
| PT (1) | PT1741716E (da) |
| WO (1) | WO2005105807A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2666098C (en) * | 2006-10-10 | 2012-09-25 | Steven D. Axt | Preparation of nucleosides ribofuranosyl pyrimidines |
| WO2008121476A1 (en) * | 2007-03-28 | 2008-10-09 | Tapestry Pharmaceuticals, Inc. | Biologically active taxane analogs and methods of treatment by oral administration |
| US8697892B2 (en) | 2010-06-30 | 2014-04-15 | Gfv, Llc | Taxane compounds, compositions and methods |
| US8785669B2 (en) | 2010-06-30 | 2014-07-22 | Gfv, Llc | Taxane compounds, compositions and methods |
| FR2986526A1 (fr) | 2012-02-03 | 2013-08-09 | Sanofi Sa | Procede de preparation de derives du taxol et certains composes intermediaires |
| SG11201406885VA (en) * | 2012-04-25 | 2014-11-27 | Gfv Llc | Taxane compounds, compositions and methods |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3746563B2 (ja) * | 1995-04-28 | 2006-02-15 | 第一製薬株式会社 | 五環性化合物 |
| TW480262B (en) * | 1995-04-28 | 2002-03-21 | Daiichi Seiyaku Co | A taxol derivative having an antitumor activity and a pharmaceutical composition comprising the same |
| US6008417A (en) * | 1997-10-20 | 1999-12-28 | Roche Vitamins Inc. | Process for making metabolites of lycopene |
| US6677456B2 (en) * | 1999-10-15 | 2004-01-13 | Daiichi Pharmaceutical Co., Ltd. | Pentacyclic taxan compound |
| MY125378A (en) * | 1999-10-15 | 2006-07-31 | Daiichi Sankyo Co Ltd | Pentacyclic taxan compound |
| JP3776818B2 (ja) * | 2001-03-07 | 2006-05-17 | 第一製薬株式会社 | 五環性タキサン化合物およびその製造方法 |
| EP1457492B1 (en) | 2001-11-29 | 2008-01-02 | Daiichi Sankyo Company, Limited | Crystals of taxane derivative and process for their production |
-
2005
- 2005-04-27 WO PCT/JP2005/008034 patent/WO2005105807A1/ja active Application Filing
- 2005-04-27 JP JP2006512820A patent/JP4800205B2/ja not_active Expired - Fee Related
- 2005-04-27 US US11/579,140 patent/US7456302B2/en active Active
- 2005-04-27 PT PT05737233T patent/PT1741716E/pt unknown
- 2005-04-27 MX MXPA06012588A patent/MXPA06012588A/es active IP Right Grant
- 2005-04-27 EP EP05737233A patent/EP1741716B8/en not_active Not-in-force
- 2005-04-27 ES ES05737233T patent/ES2371947T3/es active Active
- 2005-04-27 CN CN2005800117870A patent/CN1942473B/zh not_active Expired - Fee Related
- 2005-04-27 CA CA2565013A patent/CA2565013C/en not_active Expired - Fee Related
- 2005-04-27 KR KR1020067025289A patent/KR101186475B1/ko not_active IP Right Cessation
- 2005-04-27 AT AT05737233T patent/ATE526332T1/de active
- 2005-04-27 DK DK05737233.6T patent/DK1741716T3/da active
-
2006
- 2006-10-29 IL IL178918A patent/IL178918A/en not_active IP Right Cessation
-
2007
- 2007-02-15 HK HK07101873.3A patent/HK1094582A1/xx not_active IP Right Cessation
-
2008
- 2008-09-25 US US12/238,070 patent/US7678919B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20070167630A1 (en) | 2007-07-19 |
| KR20070026553A (ko) | 2007-03-08 |
| EP1741716B1 (en) | 2011-09-28 |
| ES2371947T3 (es) | 2012-01-11 |
| IL178918A (en) | 2011-06-30 |
| US20090030209A1 (en) | 2009-01-29 |
| CN1942473A (zh) | 2007-04-04 |
| CA2565013C (en) | 2013-01-08 |
| MXPA06012588A (es) | 2007-01-31 |
| EP1741716B8 (en) | 2012-02-22 |
| ATE526332T1 (de) | 2011-10-15 |
| JP4800205B2 (ja) | 2011-10-26 |
| JPWO2005105807A1 (ja) | 2008-03-13 |
| US7456302B2 (en) | 2008-11-25 |
| PT1741716E (pt) | 2011-12-21 |
| CA2565013A1 (en) | 2005-11-10 |
| EP1741716A4 (en) | 2009-03-04 |
| CN1942473B (zh) | 2011-02-02 |
| HK1094582A1 (en) | 2007-04-04 |
| IL178918A0 (en) | 2007-03-08 |
| KR101186475B1 (ko) | 2012-09-27 |
| EP1741716A1 (en) | 2007-01-10 |
| WO2005105807A1 (ja) | 2005-11-10 |
| US7678919B2 (en) | 2010-03-16 |
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