TW200710087A - Process for the isolation of 4-(oxiranylmethoxy)-benzonitriles - Google Patents

Process for the isolation of 4-(oxiranylmethoxy)-benzonitriles

Info

Publication number
TW200710087A
TW200710087A TW095121050A TW95121050A TW200710087A TW 200710087 A TW200710087 A TW 200710087A TW 095121050 A TW095121050 A TW 095121050A TW 95121050 A TW95121050 A TW 95121050A TW 200710087 A TW200710087 A TW 200710087A
Authority
TW
Taiwan
Prior art keywords
compound
isolation
formula
oxiranylmethoxy
benzonitriles
Prior art date
Application number
TW095121050A
Other languages
Chinese (zh)
Inventor
Silke Erbeck
Oscar-Paul Kiriacescu
Anders Kronstrom
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TW200710087A publication Critical patent/TW200710087A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

There is provided a process for the isolation of a compound of formula I, or a solvate thereof, from a mixture comprising a compound of formula I and a compound of formula II, wherein the mixture of compounds of formulae I and II may be prepared by reaction of a compound of formula III, with a compound of formula IV, and wherein R1, R2 and L1 have meanings given in the description.
TW095121050A 2005-06-20 2006-06-13 Process for the isolation of 4-(oxiranylmethoxy)-benzonitriles TW200710087A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0501430 2005-06-20

Publications (1)

Publication Number Publication Date
TW200710087A true TW200710087A (en) 2007-03-16

Family

ID=37570715

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095121050A TW200710087A (en) 2005-06-20 2006-06-13 Process for the isolation of 4-(oxiranylmethoxy)-benzonitriles

Country Status (3)

Country Link
AR (1) AR057364A1 (en)
TW (1) TW200710087A (en)
WO (1) WO2006137773A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63174981A (en) * 1987-01-14 1988-07-19 Yuka Shell Epoxy Kk Purification of epoxy compound
DD283501A7 (en) * 1988-07-29 1990-10-17 Veb Arzneimittelwerk Dresden,Dd PROCESS FOR PREPARING PURE 1- (4-NITROPHENOXY) -2,3-EPOXY PROPANE
JPH0674243B2 (en) * 1989-12-27 1994-09-21 ダイソー株式会社 Optically active atenolol salt with high optical purity and process for producing atenolol
WO1998012186A1 (en) * 1996-09-18 1998-03-26 Daiso Co., Ltd. Process for the preparation of glycidyl ethers
JP3889520B2 (en) * 1999-02-17 2007-03-07 ジャパンエポキシレジン株式会社 Epoxy compound purification method
SE0101324D0 (en) * 2001-04-12 2001-04-12 Astrazeneca Ab New process

Also Published As

Publication number Publication date
WO2006137773A1 (en) 2006-12-28
AR057364A1 (en) 2007-11-28

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