DK2264019T3 - Mellemforbindelser til fremstilling af taxanderivater - Google Patents

Mellemforbindelser til fremstilling af taxanderivater

Info

Publication number
DK2264019T3
DK2264019T3 DK10177329.9T DK10177329T DK2264019T3 DK 2264019 T3 DK2264019 T3 DK 2264019T3 DK 10177329 T DK10177329 T DK 10177329T DK 2264019 T3 DK2264019 T3 DK 2264019T3
Authority
DK
Denmark
Prior art keywords
group
preparation
hydrogen
intermediate compounds
compounds
Prior art date
Application number
DK10177329.9T
Other languages
English (en)
Inventor
Gabriele Fontana
Ezio Bombardelli
Eleonora Baldelli
Maria Luisa Gelmi
Giacomo Carenzi
Donato Pocar
Arturo Battaglia
Andrea Guerrini
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of DK2264019T3 publication Critical patent/DK2264019T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DK10177329.9T 2002-09-10 2003-09-05 Mellemforbindelser til fremstilling af taxanderivater DK2264019T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001921A ITMI20021921A1 (it) 2002-09-10 2002-09-10 Funzionalizzazione della posizione 14 dei nuclei tassanici e sintesi di nuovi derivati antitumorali.
EP09155673A EP2077264B1 (en) 2002-09-10 2003-09-05 Taxane derivatives and a process for the preparation thereof

Publications (1)

Publication Number Publication Date
DK2264019T3 true DK2264019T3 (da) 2013-10-28

Family

ID=31986024

Family Applications (4)

Application Number Title Priority Date Filing Date
DK10177329.9T DK2264019T3 (da) 2002-09-10 2003-09-05 Mellemforbindelser til fremstilling af taxanderivater
DK03747971T DK1537093T3 (da) 2002-09-10 2003-09-05 Taxanderivater, som er funktionaliseret i 14-positionen, samt en fremgangsmåde til fremstilling deraf
DK09155673.8T DK2077264T3 (da) 2002-09-10 2003-09-05 Taxanderivater og fremgangsmåde til fremstilling heraf
DK10177326.5T DK2298754T3 (da) 2002-09-10 2003-09-05 Fremstilling af taxanderivater

Family Applications After (3)

Application Number Title Priority Date Filing Date
DK03747971T DK1537093T3 (da) 2002-09-10 2003-09-05 Taxanderivater, som er funktionaliseret i 14-positionen, samt en fremgangsmåde til fremstilling deraf
DK09155673.8T DK2077264T3 (da) 2002-09-10 2003-09-05 Taxanderivater og fremgangsmåde til fremstilling heraf
DK10177326.5T DK2298754T3 (da) 2002-09-10 2003-09-05 Fremstilling af taxanderivater

Country Status (20)

Country Link
US (1) US7498452B2 (da)
EP (6) EP2264019B1 (da)
JP (2) JP4690039B2 (da)
KR (1) KR101096918B1 (da)
CN (1) CN1681799A (da)
AT (1) ATE398113T1 (da)
AU (1) AU2003267049B8 (da)
CA (1) CA2498277C (da)
DE (1) DE60321577D1 (da)
DK (4) DK2264019T3 (da)
ES (4) ES2432024T3 (da)
IL (5) IL167336A (da)
IT (1) ITMI20021921A1 (da)
NO (3) NO332250B1 (da)
PL (4) PL402332A1 (da)
PT (4) PT2264019E (da)
RU (1) RU2320652C2 (da)
SG (1) SG164282A1 (da)
SI (4) SI1537093T1 (da)
WO (1) WO2004024706A2 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20012185A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
CN107056767B (zh) * 2015-12-04 2022-07-15 江苏恩华络康药物研发有限公司 用于制备水溶性紫杉烷类衍生物的方法及中间体

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504222A (en) 1993-08-20 1996-04-02 The Scripps Research Institute Transformations of taxol
IL108444A0 (en) * 1993-01-29 1994-04-12 Univ Florida State C2 taxane derivatives and pharmaceutical compositions containing them
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
IL127598A (en) 1994-01-28 2003-04-10 Upjohn Co Process for preparing isotaxol analogs
JPH09509431A (ja) 1994-11-04 1997-09-22 フアルマシア・エツセ・ピー・アー タキサン誘導体
IT1275936B1 (it) * 1995-03-17 1997-10-24 Indena Spa Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
US5811452A (en) * 1997-01-08 1998-09-22 The Research Foundation Of State University Of New York Taxoid reversal agents for drug-resistance in cancer chemotherapy and pharmaceutical compositions thereof
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
DK1307464T3 (da) * 2000-08-04 2013-03-18 Senseonics Inc Detektion af analytter i vandige miljøer
IT1318678B1 (it) * 2000-08-10 2003-08-27 Indena Spa Procedimento per la preparazione di derivati della baccatina iii.
ITMI20012186A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato

Also Published As

Publication number Publication date
EP2281820A2 (en) 2011-02-09
PT2298754E (pt) 2013-11-07
PL375625A1 (en) 2005-12-12
ES2307965T3 (es) 2008-12-01
ES2432024T3 (es) 2013-11-29
SG164282A1 (en) 2010-09-29
AU2003267049B2 (en) 2010-02-11
NO20110781L (no) 2005-05-10
CA2498277C (en) 2011-07-05
NO20051774L (no) 2005-05-10
RU2005106361A (ru) 2005-10-10
CA2498277A1 (en) 2004-03-25
RU2320652C2 (ru) 2008-03-27
ES2398324T3 (es) 2013-03-15
JP2006503030A (ja) 2006-01-26
AU2003267049A1 (en) 2004-04-30
DK2077264T3 (da) 2013-03-04
US20060122258A1 (en) 2006-06-08
JP4690039B2 (ja) 2011-06-01
EP2298754B1 (en) 2013-08-07
ES2433580T3 (es) 2013-12-11
NO332367B1 (no) 2012-09-03
IL197815A (en) 2013-02-28
EP2077264A2 (en) 2009-07-08
SI1537093T1 (sl) 2008-10-31
PL402323A1 (pl) 2013-04-02
ATE398113T1 (de) 2008-07-15
NO20110782L (no) 2005-05-10
PL402333A1 (pl) 2013-04-02
IL214430A0 (en) 2011-09-27
EP1980557A3 (en) 2008-12-31
KR20050035540A (ko) 2005-04-18
DK2298754T3 (da) 2013-11-04
EP2077264B1 (en) 2012-11-14
SI2077264T1 (sl) 2013-03-29
EP2264019B1 (en) 2013-07-24
PL402332A1 (pl) 2013-04-02
SI2264019T1 (sl) 2013-10-30
IL167336A (en) 2009-11-18
CN1681799A (zh) 2005-10-12
US7498452B2 (en) 2009-03-03
SI2298754T1 (sl) 2013-11-29
EP2298754A1 (en) 2011-03-23
EP1537093B1 (en) 2008-06-11
NO332250B1 (no) 2012-08-06
IL214432A0 (en) 2011-09-27
WO2004024706A3 (en) 2004-07-08
IL214431A (en) 2014-05-28
EP2281820A3 (en) 2011-05-04
KR101096918B1 (ko) 2011-12-22
ITMI20021921A1 (it) 2004-03-11
PT2264019E (pt) 2013-10-28
NO332366B1 (no) 2012-09-03
DE60321577D1 (de) 2008-07-24
EP1537093A2 (en) 2005-06-08
IL214432A (en) 2014-05-28
EP2298754B9 (en) 2013-12-18
JP2010270145A (ja) 2010-12-02
AU2003267049B8 (en) 2010-03-04
IL214431A0 (en) 2011-09-27
WO2004024706A2 (en) 2004-03-25
EP2264019A1 (en) 2010-12-22
DK1537093T3 (da) 2008-10-27
PT2077264E (pt) 2013-01-29
EP2077264A3 (en) 2009-09-16
PT1537093E (pt) 2008-09-02
EP1980557A2 (en) 2008-10-15

Similar Documents

Publication Publication Date Title
DK1706414T3 (da) Fremgangsmåde til fluorcytidinderivater
ES2111572T3 (es) Nuevo derivado de benzopirano.
PT1157018E (pt) Processo para a preparacao de taxanos a partir de 10-desacetilbacatina iii
NO20061424L (no) Fremgangsmote for fremstillingen av THIP
TR200302288T2 (tr) Terapi için yeni bileşikler ve metotlar.
WO2004075858A3 (en) Flavone acetic acid analogs and methods of use thereof
TW200505446A (en) Inhibitor of cox
DK2264019T3 (da) Mellemforbindelser til fremstilling af taxanderivater
DK1156058T3 (da) Fremgangsmåde til fremstilling af (E,Z) 3-(2-aminoethoxyimino)-androstan-6,17-dion og analoger deraf
DE69912984D1 (de) Derivate des 6-(4-phenylbutoxy)hexylamins und verfahren zur herstellung von salmeterol
DK1105392T3 (da) Fremgangsmåde til fremstilling af mellemprodukter for imidazodiazepin
PT1205476E (pt) Processo de sintese de derivados n-(mercapto-acil)-aminoacidos a partir de acidos acrilicos alfa-substituidos
DK1009749T3 (da) Fremstilling af (S)-N-tert.butyl-1,2,3,4-tetrahydroisoquinolin-3-carboxyamid
DK0985665T3 (da) Fremgangsmåde til fremstilling af 3-amino-2-oxo-pyrrolidiner, mellemprodukter og anvendelse af disse
DK1193260T3 (da) Phenoxazinanaloger til behandling af amyloidosis
EA199800931A1 (ru) Способ получения ингибиторов фосфодиэстеразы iv
WO2002088091A3 (en) Inhibitors of human rhinovirus 2a cysteine protease
DK1282625T3 (da) Anvendelsen af benzoxaziner i behandlingen af Parkinsons sygdom
DE60230924D1 (de) 2-substituierte vitamin-d-derivate
TH41548A (th) อนุพันธ์ 2-(3h)-ออกซาโซโลนชนิดใหม่
KR970065536A (ko) 신규 2-(피페라진-1-일)티아졸-4-카르복실산 유도체, 그의 제조방법 및 식물병원균 퇴치를 위한 그의 용도
TH66462A (th) อิมิดาโซลินิลเมททิลอะรัลคิลซัลโฟนาไมด์