DK1193260T3 - Phenoxazinanaloger til behandling af amyloidosis - Google Patents

Phenoxazinanaloger til behandling af amyloidosis

Info

Publication number
DK1193260T3
DK1193260T3 DK01122733T DK01122733T DK1193260T3 DK 1193260 T3 DK1193260 T3 DK 1193260T3 DK 01122733 T DK01122733 T DK 01122733T DK 01122733 T DK01122733 T DK 01122733T DK 1193260 T3 DK1193260 T3 DK 1193260T3
Authority
DK
Denmark
Prior art keywords
hydrogen
lower alkyl
phenoxazine
amyloidosis
analogues
Prior art date
Application number
DK01122733T
Other languages
English (en)
Inventor
Corinne Elizab Augelli-Szafran
Yingije Lai
Tomoyuki Yasunaga
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of DK1193260T3 publication Critical patent/DK1193260T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/38—[b, e]-condensed with two six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK01122733T 2000-09-29 2001-09-21 Phenoxazinanaloger til behandling af amyloidosis DK1193260T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23696600P 2000-09-29 2000-09-29

Publications (1)

Publication Number Publication Date
DK1193260T3 true DK1193260T3 (da) 2006-04-10

Family

ID=22891762

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01122733T DK1193260T3 (da) 2000-09-29 2001-09-21 Phenoxazinanaloger til behandling af amyloidosis

Country Status (10)

Country Link
US (1) US20020143012A1 (da)
EP (1) EP1193260B1 (da)
JP (1) JP2002201186A (da)
AT (1) ATE312086T1 (da)
BR (1) BR0104344A (da)
CA (1) CA2357450A1 (da)
DE (1) DE60115569T2 (da)
DK (1) DK1193260T3 (da)
ES (1) ES2253315T3 (da)
MX (1) MXPA01009768A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1656141B1 (en) * 2003-08-07 2010-04-14 MERCK SHARP & DOHME LTD. Treatment for alzheimer s disease and related conditions
CA2535873A1 (en) * 2003-08-18 2005-02-24 Novartis Ag 3h-phenoxazine derivatives suitable as near-infrared imaging agents, preparation an use thereof
GB0410238D0 (en) * 2004-05-07 2004-06-09 Merck Sharp & Dohme Therapeutic agents
WO2008058402A1 (en) * 2006-11-17 2008-05-22 Queen's University At Kingston Compounds and methods for treating protein folding disorders
WO2014032732A1 (de) 2012-08-28 2014-03-06 Eberhard Karls Universität Tübingen Medizinische Fakultät Halogenierte benzoxazine und ihre verwendung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506197D0 (en) * 1995-03-27 1995-05-17 Hoffmann La Roche Inhibition of tau-tau association.
CN1156445C (zh) * 1999-06-10 2004-07-07 沃尼尔·朗伯公司 采用二氢异吲哚衍生物抑制淀粉样蛋白聚集和使淀粉样蛋白沉积成像的方法
DZ3252A1 (da) * 1999-06-10 2000-12-21 Warner Lambert Co

Also Published As

Publication number Publication date
DE60115569D1 (de) 2006-01-12
ATE312086T1 (de) 2005-12-15
ES2253315T3 (es) 2006-06-01
MXPA01009768A (es) 2004-08-12
CA2357450A1 (en) 2002-03-29
DE60115569T2 (de) 2006-08-10
EP1193260A1 (en) 2002-04-03
BR0104344A (pt) 2003-03-05
JP2002201186A (ja) 2002-07-16
US20020143012A1 (en) 2002-10-03
EP1193260B1 (en) 2005-12-07

Similar Documents

Publication Publication Date Title
PT1184376E (pt) Novos derivados heterociclicos de carboxamida
EA200200661A1 (ru) 3-аминохиназолин-2,4-дионовые антибактериальные агенты
EA200602170A1 (ru) Производные пиперидина, композиции на их основе, способы их применения
WO2003016291A1 (fr) Activateur du recepteur $g(d) sensible au proliferateur de peroxysome
TR200102957T2 (tr) Sitalopram hazırlanması için metod.
DE60315265D1 (de) Stickstoffhaltige heterocyclische verbindung und arzneimittel davon
WO2005061458A3 (en) Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
TR200101893T2 (tr) Antiviral maddeler olarak 4-okso-1,4 dihidro -3- kuinolinkarboksamitler.
DK1767535T3 (da) Syntese af epothiloner, mellemprodukter deraf, analoge og deres anvendelse
RU2005117789A (ru) Производные 4,5-диарилтиазола в качестве лигандов св-1
EA200700441A1 (ru) НОВЫЕ ГЕТЕРОЦИКЛИЧЕСКИЕ ИНГИБИТОРЫ NF-κB
BR0213660A (pt) Composto, composição farmacêutica e método para tratar pacientes
DK0959906T3 (da) Delta 1,6 bicyclo[4,4,0] funktionelle farver til kontrastforøgelse ved optisk afbildning
ATE452882T1 (de) Herstellung von quetiapin
HRP20090264T1 (en) Phenyl-piperazin methanone derivatives
PT918776E (pt) Sintese total de acilfulvenos antitumorais
NO20013684L (no) Substituerte fenetylaminderivater
DK0759027T3 (da) Bicykliske amidinderivater som inhibitorer af nitrogenoxidsynthetase
AU2001255646A1 (en) Method of inhibiting amyloid protein aggregation and imaging amyloid deposits using aminoindane derivatives
EA200100090A2 (ru) Новые пиперидин-4-сульфонамидные производные, способ их получения и содержащие их фармацевтические композиции
ES2191341T3 (es) Derivados de la 2-fenoxianilina.
DK1193260T3 (da) Phenoxazinanaloger til behandling af amyloidosis
BR0209901A (pt) Processos para a sìntese de derivados de 2,3-dihidro-1,4-dioxino-[2,3-f] quinolina
DK1059283T3 (da) Fremgangsmåde til fremstilling af neuraminidase-inhibitor ro-64-0796
TR200302288T2 (tr) Terapi için yeni bileşikler ve metotlar.