IT1318678B1 - Procedimento per la preparazione di derivati della baccatina iii. - Google Patents

Procedimento per la preparazione di derivati della baccatina iii.

Info

Publication number
IT1318678B1
IT1318678B1 IT2000MI001869A ITMI20001869A IT1318678B1 IT 1318678 B1 IT1318678 B1 IT 1318678B1 IT 2000MI001869 A IT2000MI001869 A IT 2000MI001869A IT MI20001869 A ITMI20001869 A IT MI20001869A IT 1318678 B1 IT1318678 B1 IT 1318678B1
Authority
IT
Italy
Prior art keywords
preparation
procedure
derivatives iii
baccatin derivatives
iii
Prior art date
Application number
IT2000MI001869A
Other languages
English (en)
Inventor
Alessandro Pontiroli
Ezio Bombardelli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of ITMI20001869A0 publication Critical patent/ITMI20001869A0/it
Priority to IT2000MI001869A priority Critical patent/IT1318678B1/it
Priority to KR1020037001790A priority patent/KR100853056B1/ko
Priority to AU8204001A priority patent/AU8204001A/xx
Priority to ES01960578T priority patent/ES2228929T3/es
Priority to CNB018138675A priority patent/CN1254470C/zh
Priority to CNB2005100873136A priority patent/CN100349882C/zh
Priority to EP01960578A priority patent/EP1307436B1/en
Priority to DE60106057T priority patent/DE60106057T2/de
Priority to HU0303832A priority patent/HU229316B1/hu
Priority to DK01960578T priority patent/DK1307436T3/da
Priority to AU2001282040A priority patent/AU2001282040B8/en
Priority to CNA2007101617507A priority patent/CN101130528A/zh
Priority to JP2002518192A priority patent/JP4907043B2/ja
Priority to IL15433001A priority patent/IL154330A0/xx
Priority to US10/343,991 priority patent/US6828445B2/en
Priority to PCT/EP2001/008730 priority patent/WO2002012215A1/en
Priority to CZ20030365A priority patent/CZ302810B6/cs
Priority to SK159-2003A priority patent/SK286653B6/sk
Priority to PL360087A priority patent/PL200868B1/pl
Priority to RU2003103776/04A priority patent/RU2264394C2/ru
Priority to PT01960578T priority patent/PT1307436E/pt
Priority to CA002418829A priority patent/CA2418829C/en
Priority to AT01960578T priority patent/ATE277919T1/de
Priority to SI200130208T priority patent/SI1307436T1/xx
Publication of ITMI20001869A1 publication Critical patent/ITMI20001869A1/it
Priority to IL154330A priority patent/IL154330A/en
Priority to NO20030609A priority patent/NO328124B1/no
Application granted granted Critical
Publication of IT1318678B1 publication Critical patent/IT1318678B1/it
Priority to HK03108269A priority patent/HK1055964A1/xx
Priority to US10/972,674 priority patent/US7078538B2/en
Priority to HK06108866A priority patent/HK1088325A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT2000MI001869A 2000-08-10 2000-08-10 Procedimento per la preparazione di derivati della baccatina iii. IT1318678B1 (it)

Priority Applications (29)

Application Number Priority Date Filing Date Title
IT2000MI001869A IT1318678B1 (it) 2000-08-10 2000-08-10 Procedimento per la preparazione di derivati della baccatina iii.
US10/343,991 US6828445B2 (en) 2000-08-10 2001-07-27 Process for the preparation of baccatin III derivatives
SK159-2003A SK286653B6 (sk) 2000-08-10 2001-07-27 Spôsob prípravy 14ß-hydroxy-1,14-karbonát-deacetylbakatínu III a medziprodukty
PCT/EP2001/008730 WO2002012215A1 (en) 2000-08-10 2001-07-27 Process for the preparation of baccatin iii derivatives
CNB018138675A CN1254470C (zh) 2000-08-10 2001-07-27 浆果赤霉素ⅲ衍生物的制备方法
CNB2005100873136A CN100349882C (zh) 2000-08-10 2001-07-27 浆果赤霉素ⅲ衍生物的制备方法
EP01960578A EP1307436B1 (en) 2000-08-10 2001-07-27 Process for the preparation of baccatin iii derivatives
DE60106057T DE60106057T2 (de) 2000-08-10 2001-07-27 Verfahren zur herstellung von baccatin iii-derivativen
HU0303832A HU229316B1 (en) 2000-08-10 2001-07-27 Process for preparation of baccatin iii derivatives
DK01960578T DK1307436T3 (da) 2000-08-10 2001-07-27 Fremgangsmåde til fremstilling af baccatin III-derivater
AU2001282040A AU2001282040B8 (en) 2000-08-10 2001-07-27 Process for the preparation of baccatin III derivatives
CNA2007101617507A CN101130528A (zh) 2000-08-10 2001-07-27 浆果赤霉素ⅲ衍生物的制备方法
JP2002518192A JP4907043B2 (ja) 2000-08-10 2001-07-27 バッカチンｉｉｉ誘導体の調製方法
IL15433001A IL154330A0 (en) 2000-08-10 2001-07-27 Process for the preparation of baccatin iii derivatives
KR1020037001790A KR100853056B1 (ko) 2000-08-10 2001-07-27 바카틴ⅲ 유도체의 제조방법
ES01960578T ES2228929T3 (es) 2000-08-10 2001-07-27 Procedimiento de preparacion de derivados de baccatina iii.
CZ20030365A CZ302810B6 (cs) 2000-08-10 2001-07-27 Zpusob výroby 14beta-hydroxy-1,14-karbonátdeacetylbaccatinu III
SI200130208T SI1307436T1 (en) 2000-08-10 2001-07-27 Process for the preparation of baccatin iii derivatives
PL360087A PL200868B1 (pl) 2000-08-10 2001-07-27 Sposób wytwarzania 1,14-węglanu 14ß-hydroksy-10-deacetylobakatyny III oraz związki pośrednie
RU2003103776/04A RU2264394C2 (ru) 2000-08-10 2001-07-27 Способ получения производных баккатина iii
PT01960578T PT1307436E (pt) 2000-08-10 2001-07-27 Processo para a preparacao de derivados de bacatina iii
CA002418829A CA2418829C (en) 2000-08-10 2001-07-27 Process for the preparation of baccatin iii derivatives
AT01960578T ATE277919T1 (de) 2000-08-10 2001-07-27 Verfahren zur herstellung von baccatin iii- derivativen
AU8204001A AU8204001A (en) 2000-08-10 2001-07-27 Process for the preparation of baccatin iii derivatives
IL154330A IL154330A (en) 2000-08-10 2003-02-06 Process for the preparation of derivatives of bacatin III
NO20030609A NO328124B1 (no) 2000-08-10 2003-02-07 Fremgangsmate for fremstilling av baccatin III-derivater
HK03108269A HK1055964A1 (en) 2000-08-10 2003-11-13 Process for the preparation of baccatin iii derivatives
US10/972,674 US7078538B2 (en) 2000-08-10 2004-10-26 Baccatin III derivatives
HK06108866A HK1088325A1 (en) 2000-08-10 2006-08-10 Process for the preparation of baccatin III derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI001869A IT1318678B1 (it) 2000-08-10 2000-08-10 Procedimento per la preparazione di derivati della baccatina iii.

Publications (3)

Publication Number Publication Date
ITMI20001869A0 ITMI20001869A0 (it) 2000-08-10
ITMI20001869A1 ITMI20001869A1 (it) 2002-02-10
IT1318678B1 true IT1318678B1 (it) 2003-08-27

Family

ID=11445705

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000MI001869A IT1318678B1 (it) 2000-08-10 2000-08-10 Procedimento per la preparazione di derivati della baccatina iii.

Country Status (23)

Country Link
US (2) US6828445B2 (it)
EP (1) EP1307436B1 (it)
JP (1) JP4907043B2 (it)
KR (1) KR100853056B1 (it)
CN (3) CN101130528A (it)
AT (1) ATE277919T1 (it)
AU (2) AU8204001A (it)
CA (1) CA2418829C (it)
CZ (1) CZ302810B6 (it)
DE (1) DE60106057T2 (it)
DK (1) DK1307436T3 (it)
ES (1) ES2228929T3 (it)
HK (2) HK1055964A1 (it)
HU (1) HU229316B1 (it)
IL (2) IL154330A0 (it)
IT (1) IT1318678B1 (it)
NO (1) NO328124B1 (it)
PL (1) PL200868B1 (it)
PT (1) PT1307436E (it)
RU (1) RU2264394C2 (it)
SI (1) SI1307436T1 (it)
SK (1) SK286653B6 (it)
WO (1) WO2002012215A1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1320107B1 (it) * 2000-11-28 2003-11-18 Indena Spa Procedimento per la preparazione di derivati tassanici.
ITMI20012185A1 (it) 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012186A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
ITMI20021921A1 (it) 2002-09-10 2004-03-11 Indena Spa Funzionalizzazione della posizione 14 dei nuclei tassanici e sintesi di nuovi derivati antitumorali.
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
ITMI20050614A1 (it) * 2005-04-12 2006-10-13 Indena Spa Processo per la purificazione della 10-deacetilbaccatina iii dalla 10-deacetil-2-debenzoil-2-pentenoilbaccatina iii
US20080151139A1 (en) * 2006-12-22 2008-06-26 Itt Manufacturing Enterprises, Inc. Addressable backlight for LCD panel
ES2389518T3 (es) 2008-01-18 2012-10-26 Indena S.P.A. Formas sólidas de ortataxel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698712A (en) * 1992-03-06 1997-12-16 Indena S.P.A. Baccatine III derivatives
IT1275936B1 (it) * 1995-03-17 1997-10-24 Indena Spa Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
FR2732341A1 (fr) * 1995-03-27 1996-10-04 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
IT1275435B (it) 1995-05-19 1997-08-07 Indena Spa Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono
KR100345047B1 (ko) * 1998-01-26 2002-07-19 한미약품공업 주식회사 신규한 탁산테르핀계 화합물
IT1308636B1 (it) * 1999-03-02 2002-01-09 Indena Spa Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii.
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
IT1320107B1 (it) * 2000-11-28 2003-11-18 Indena Spa Procedimento per la preparazione di derivati tassanici.

Also Published As

Publication number Publication date
HUP0303832A2 (hu) 2004-03-01
EP1307436A1 (en) 2003-05-07
SK1592003A3 (en) 2003-07-01
HK1055964A1 (en) 2004-01-30
NO20030609L (no) 2003-02-07
CA2418829A1 (en) 2002-02-14
DE60106057D1 (de) 2004-11-04
EP1307436B1 (en) 2004-09-29
HU229316B1 (en) 2013-10-28
ITMI20001869A0 (it) 2000-08-10
JP4907043B2 (ja) 2012-03-28
CA2418829C (en) 2009-12-29
JP2004505961A (ja) 2004-02-26
RU2264394C2 (ru) 2005-11-20
CN101130528A (zh) 2008-02-27
HUP0303832A3 (en) 2005-02-28
HK1088325A1 (en) 2006-11-03
ES2228929T3 (es) 2005-04-16
WO2002012215A1 (en) 2002-02-14
KR20030020454A (ko) 2003-03-08
CN100349882C (zh) 2007-11-21
US20040014998A1 (en) 2004-01-22
PL200868B1 (pl) 2009-02-27
CN1446207A (zh) 2003-10-01
CN1254470C (zh) 2006-05-03
AU8204001A (en) 2002-02-18
KR100853056B1 (ko) 2008-08-19
IL154330A (en) 2006-12-31
NO328124B1 (no) 2009-12-14
DE60106057T2 (de) 2006-02-23
AU2001282040B2 (en) 2005-09-15
CZ302810B6 (cs) 2011-11-23
SK286653B6 (sk) 2009-03-05
US6828445B2 (en) 2004-12-07
ATE277919T1 (de) 2004-10-15
DK1307436T3 (da) 2005-01-31
CZ2003365A3 (cs) 2003-06-18
IL154330A0 (en) 2003-09-17
PT1307436E (pt) 2004-11-30
CN1736995A (zh) 2006-02-22
US20050113585A1 (en) 2005-05-26
NO20030609D0 (no) 2003-02-07
US7078538B2 (en) 2006-07-18
AU2001282040B8 (en) 2006-01-19
SI1307436T1 (en) 2005-02-28
ITMI20001869A1 (it) 2002-02-10
PL360087A1 (en) 2004-09-06

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