RU2095354C1 - Тиазолидиновые соединения, способы их получения, способ снижения содержания сахара в крови у млекопитающих - Google Patents

Тиазолидиновые соединения, способы их получения, способ снижения содержания сахара в крови у млекопитающих Download PDF

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Publication number
RU2095354C1
RU2095354C1 RU9292016231A RU92016231A RU2095354C1 RU 2095354 C1 RU2095354 C1 RU 2095354C1 RU 9292016231 A RU9292016231 A RU 9292016231A RU 92016231 A RU92016231 A RU 92016231A RU 2095354 C1 RU2095354 C1 RU 2095354C1
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RU
Russia
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group
thiazolidine
compound
benzyl
hydrogen atom
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RU9292016231A
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English (en)
Russian (ru)
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RU92016231A (ru
Inventor
Йосиока Такао
Ниси Такахиде
Канаи Цутому
Айзава Юити
Вада Кунио
Фудзита Такаси
Хорикоси Хиройоси
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Санкио Компани Лимитед
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Publication of RU92016231A publication Critical patent/RU92016231A/ru
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RU9292016231A 1991-12-26 1992-12-25 Тиазолидиновые соединения, способы их получения, способ снижения содержания сахара в крови у млекопитающих RU2095354C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3-344571 1991-12-26
JP34457191 1991-12-26

Publications (2)

Publication Number Publication Date
RU92016231A RU92016231A (ru) 1995-05-20
RU2095354C1 true RU2095354C1 (ru) 1997-11-10

Family

ID=18370304

Family Applications (1)

Application Number Title Priority Date Filing Date
RU9292016231A RU2095354C1 (ru) 1991-12-26 1992-12-25 Тиазолидиновые соединения, способы их получения, способ снижения содержания сахара в крови у млекопитающих

Country Status (21)

Country Link
EP (1) EP0549365B1 (enExample)
JP (1) JP2833949B2 (enExample)
CN (1) CN1032751C (enExample)
AT (1) ATE126221T1 (enExample)
AU (1) AU654223B2 (enExample)
CA (1) CA2086277A1 (enExample)
CZ (1) CZ389792A3 (enExample)
DE (1) DE69204041T2 (enExample)
DK (1) DK0549365T3 (enExample)
ES (1) ES2078671T3 (enExample)
FI (1) FI925849A7 (enExample)
GR (1) GR3017632T3 (enExample)
HK (1) HK196095A (enExample)
HU (1) HU215450B (enExample)
IL (1) IL104238A (enExample)
MX (1) MX9207595A (enExample)
NO (1) NO302471B1 (enExample)
NZ (1) NZ245612A (enExample)
RU (1) RU2095354C1 (enExample)
TW (1) TW211007B (enExample)
ZA (1) ZA9210021B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2151145C1 (ru) * 1994-04-11 2000-06-20 Санкио Компани Лимитед Промежуточное соединение для получения гетероциклических соединений, обладающих антидиабетической активностью
RU2218336C2 (ru) * 1999-06-10 2003-12-10 Пробиодруг Аг Способ получения тиазолидина
RU2226195C2 (ru) * 1998-06-24 2004-03-27 Пробиодруг Аг Соединения нестабильных ингибиторов дипептидилпептидазы iv
RU2226533C2 (ru) * 1998-06-24 2004-04-10 Пробиодруг Аг Пролекарства ингибиторов дипептидилпептидазы iv

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
EP0783888A1 (en) * 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
US6331633B1 (en) * 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
ATE310733T1 (de) * 2000-04-21 2005-12-15 Pfizer Prod Inc Thyroid-rezeptorliganden
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
WO2001081328A2 (en) * 2000-04-24 2001-11-01 Aryx Therapeutics Thiazolidinedione analogues and their use for the treatment of diabetes
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法
RU2445957C2 (ru) 2006-03-16 2012-03-27 Метаболик Солюшнз Девелопмент Компани Аналоги тиазолидиндиона
JP5149271B2 (ja) 2006-03-16 2013-02-20 メタボリック ソリューションズ ディベロップメント カンパニー， エルエルシー 高血圧症を処置するためならびに脂質を下げるためのチアゾリジンジオン類似体
AU2008301905B2 (en) * 2007-09-14 2013-06-27 Cirius Therapeutics, Inc. Thiazolidinedione analogues for the treatment of hypertension
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
HUE038042T2 (hu) 2009-12-15 2018-09-28 Cirius Therapeutics Inc PPAR helyettesítõ tiazolidindion sók metabolikus betegségek kezelésére
MX2012012092A (es) * 2010-04-19 2012-12-17 Metabolic Solutions Dev Co Llc Sintesis novedosa para compuestos de tiazolidinadiona.
EP2560615A1 (en) * 2010-04-21 2013-02-27 Metabolic Solutions Development Company LLC Thiazolidinedione analogues
HUE031424T2 (en) 2010-08-10 2017-07-28 Octeta Therapeutics Llc New synthesis of thiazolidinedione compounds
CN115433144B (zh) * 2022-10-09 2023-09-19 燃点(南京)生物医药科技有限公司 一种脂肪酸酯类化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент ЕПВ N 441605, кл. C 07 D 277/34, 1991. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2151145C1 (ru) * 1994-04-11 2000-06-20 Санкио Компани Лимитед Промежуточное соединение для получения гетероциклических соединений, обладающих антидиабетической активностью
RU2226195C2 (ru) * 1998-06-24 2004-03-27 Пробиодруг Аг Соединения нестабильных ингибиторов дипептидилпептидазы iv
RU2226533C2 (ru) * 1998-06-24 2004-04-10 Пробиодруг Аг Пролекарства ингибиторов дипептидилпептидазы iv
RU2218336C2 (ru) * 1999-06-10 2003-12-10 Пробиодруг Аг Способ получения тиазолидина

Also Published As

Publication number Publication date
IL104238A (en) 1996-10-31
EP0549365B1 (en) 1995-08-09
NO302471B1 (no) 1998-03-09
ATE126221T1 (de) 1995-08-15
FI925849A0 (fi) 1992-12-23
CA2086277A1 (en) 1993-06-27
HUT67788A (en) 1995-04-28
AU3043192A (en) 1993-07-01
NO924964L (no) 1993-06-28
FI925849A7 (fi) 1993-06-27
MX9207595A (es) 1994-06-30
CN1032751C (zh) 1996-09-11
DE69204041T2 (de) 1996-03-28
DK0549365T3 (da) 1995-12-18
CN1074680A (zh) 1993-07-28
AU654223B2 (en) 1994-10-27
ES2078671T3 (es) 1995-12-16
EP0549365A1 (en) 1993-06-30
JP2833949B2 (ja) 1998-12-09
NZ245612A (en) 1994-06-27
GR3017632T3 (en) 1996-01-31
DE69204041D1 (de) 1995-09-14
CZ389792A3 (en) 1994-01-19
HK196095A (en) 1996-01-05
JPH05239041A (ja) 1993-09-17
NO924964D0 (no) 1992-12-22
HU215450B (hu) 1999-04-28
HU9204130D0 (en) 1993-04-28
TW211007B (enExample) 1993-08-11
ZA9210021B (en) 1993-07-02

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