IL104238A - Thiazolidine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents
Thiazolidine derivatives processes for the preparation thereof and pharmaceutical compositions containing the sameInfo
- Publication number
- IL104238A IL104238A IL10423892A IL10423892A IL104238A IL 104238 A IL104238 A IL 104238A IL 10423892 A IL10423892 A IL 10423892A IL 10423892 A IL10423892 A IL 10423892A IL 104238 A IL104238 A IL 104238A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- group
- formula
- carbon atoms
- thiazolidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP34457191 | 1991-12-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL104238A true IL104238A (en) | 1996-10-31 |
Family
ID=18370304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10423892A IL104238A (en) | 1991-12-26 | 1992-12-25 | Thiazolidine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0549365B1 (enExample) |
| JP (1) | JP2833949B2 (enExample) |
| CN (1) | CN1032751C (enExample) |
| AT (1) | ATE126221T1 (enExample) |
| AU (1) | AU654223B2 (enExample) |
| CA (1) | CA2086277A1 (enExample) |
| CZ (1) | CZ389792A3 (enExample) |
| DE (1) | DE69204041T2 (enExample) |
| DK (1) | DK0549365T3 (enExample) |
| ES (1) | ES2078671T3 (enExample) |
| FI (1) | FI925849A7 (enExample) |
| GR (1) | GR3017632T3 (enExample) |
| HK (1) | HK196095A (enExample) |
| HU (1) | HU215450B (enExample) |
| IL (1) | IL104238A (enExample) |
| MX (1) | MX9207595A (enExample) |
| NO (1) | NO302471B1 (enExample) |
| NZ (1) | NZ245612A (enExample) |
| RU (1) | RU2095354C1 (enExample) |
| TW (1) | TW211007B (enExample) |
| ZA (1) | ZA9210021B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO302519B1 (no) * | 1991-12-26 | 1998-03-16 | Sankyo Co | Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat |
| CA2146701A1 (en) * | 1994-04-11 | 1995-10-12 | Takashi Fujita | Heterocyclic compounds having anti-diabetic activity, their preparation and their use |
| EP0783888A1 (en) | 1995-12-26 | 1997-07-16 | Sankyo Company Limited | Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis |
| US6331633B1 (en) * | 1998-05-08 | 2001-12-18 | Calyx Therapeutics Inc. | Heterocyclic analogs of diphenylethylene compounds |
| DE19828113A1 (de) * | 1998-06-24 | 2000-01-05 | Probiodrug Ges Fuer Arzneim | Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV |
| DE19828114A1 (de) * | 1998-06-24 | 2000-01-27 | Probiodrug Ges Fuer Arzneim | Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV |
| DE19926233C1 (de) * | 1999-06-10 | 2000-10-19 | Probiodrug Ges Fuer Arzneim | Verfahren zur Herstellung von Thiazolidin |
| US6620830B2 (en) | 2000-04-21 | 2003-09-16 | Pfizer, Inc. | Thyroid receptor ligands |
| DE60115132T2 (de) * | 2000-04-21 | 2006-07-06 | Pfizer Products Inc., Groton | Thyroid-Rezeptorliganden |
| US6680387B2 (en) | 2000-04-24 | 2004-01-20 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| US6768008B2 (en) | 2000-04-24 | 2004-07-27 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| CA2402123A1 (en) * | 2000-04-24 | 2001-11-01 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| JP2003040877A (ja) * | 2001-07-24 | 2003-02-13 | Sumika Fine Chemicals Co Ltd | ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法 |
| NZ571870A (en) | 2006-03-16 | 2011-07-29 | Metabolic Solutions Dev Co | Thiazolidinedione analogues for the treatment of hypertension and for lowering lipids |
| AU2007227581B2 (en) | 2006-03-16 | 2012-11-08 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease |
| WO2009038681A1 (en) * | 2007-09-14 | 2009-03-26 | Metabolic Solutions Development Company | Thiazolidinedione analogues for the treatment of hypertension |
| US8304441B2 (en) | 2007-09-14 | 2012-11-06 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues for the treatment of metabolic diseases |
| NZ600390A (en) | 2009-12-15 | 2013-08-30 | Metabolic Solutions Dev Co Llc | Ppar-sparing thiazolidinedione salts for the treatment of metabolic diseases |
| MX2012012092A (es) * | 2010-04-19 | 2012-12-17 | Metabolic Solutions Dev Co Llc | Sintesis novedosa para compuestos de tiazolidinadiona. |
| AU2011242844A1 (en) * | 2010-04-21 | 2012-11-01 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues |
| NZ606574A (en) | 2010-08-10 | 2015-02-27 | Metabolic Solutions Dev Co Llc | Novel synthesis for thiazolidinedione compounds |
| CN115433144B (zh) * | 2022-10-09 | 2023-09-19 | 燃点(南京)生物医药科技有限公司 | 一种脂肪酸酯类化合物及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
| JPH06779B2 (ja) * | 1985-06-10 | 1994-01-05 | 武田薬品工業株式会社 | チアゾリジオン誘導体およびそれを含んでなる医薬組成物 |
| US5143930A (en) * | 1990-02-07 | 1992-09-01 | Sankyo Company, Limited | Thiazolidine derivatives with anti-diabetic activity, their preparation and their use |
| NO302519B1 (no) * | 1991-12-26 | 1998-03-16 | Sankyo Co | Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat |
-
1992
- 1992-12-22 NO NO924964A patent/NO302471B1/no unknown
- 1992-12-23 NZ NZ245612A patent/NZ245612A/en unknown
- 1992-12-23 ZA ZA9210021A patent/ZA9210021B/xx unknown
- 1992-12-23 HU HUP9204130A patent/HU215450B/hu not_active IP Right Cessation
- 1992-12-23 FI FI925849A patent/FI925849A7/fi not_active Application Discontinuation
- 1992-12-24 AU AU30431/92A patent/AU654223B2/en not_active Ceased
- 1992-12-24 DK DK92311813.7T patent/DK0549365T3/da active
- 1992-12-24 TW TW081110354A patent/TW211007B/zh active
- 1992-12-24 EP EP92311813A patent/EP0549365B1/en not_active Expired - Lifetime
- 1992-12-24 AT AT92311813T patent/ATE126221T1/de not_active IP Right Cessation
- 1992-12-24 CA CA002086277A patent/CA2086277A1/en not_active Abandoned
- 1992-12-24 ES ES92311813T patent/ES2078671T3/es not_active Expired - Lifetime
- 1992-12-24 DE DE69204041T patent/DE69204041T2/de not_active Expired - Fee Related
- 1992-12-25 IL IL10423892A patent/IL104238A/en not_active IP Right Cessation
- 1992-12-25 JP JP4346122A patent/JP2833949B2/ja not_active Expired - Fee Related
- 1992-12-25 RU RU9292016231A patent/RU2095354C1/ru active
- 1992-12-26 CN CN92115234A patent/CN1032751C/zh not_active Expired - Fee Related
- 1992-12-28 CZ CS923897A patent/CZ389792A3/cs unknown
- 1992-12-28 MX MX9207595A patent/MX9207595A/es not_active IP Right Cessation
-
1995
- 1995-10-04 GR GR950402745T patent/GR3017632T3/el unknown
- 1995-12-28 HK HK196095A patent/HK196095A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2095354C1 (ru) | 1997-11-10 |
| DE69204041D1 (de) | 1995-09-14 |
| ATE126221T1 (de) | 1995-08-15 |
| FI925849A7 (fi) | 1993-06-27 |
| CN1032751C (zh) | 1996-09-11 |
| AU654223B2 (en) | 1994-10-27 |
| FI925849A0 (fi) | 1992-12-23 |
| MX9207595A (es) | 1994-06-30 |
| AU3043192A (en) | 1993-07-01 |
| GR3017632T3 (en) | 1996-01-31 |
| HU9204130D0 (en) | 1993-04-28 |
| ZA9210021B (en) | 1993-07-02 |
| CA2086277A1 (en) | 1993-06-27 |
| EP0549365A1 (en) | 1993-06-30 |
| NO302471B1 (no) | 1998-03-09 |
| JP2833949B2 (ja) | 1998-12-09 |
| CN1074680A (zh) | 1993-07-28 |
| DK0549365T3 (da) | 1995-12-18 |
| DE69204041T2 (de) | 1996-03-28 |
| NZ245612A (en) | 1994-06-27 |
| HU215450B (hu) | 1999-04-28 |
| EP0549365B1 (en) | 1995-08-09 |
| NO924964L (no) | 1993-06-28 |
| HK196095A (en) | 1996-01-05 |
| ES2078671T3 (es) | 1995-12-16 |
| CZ389792A3 (en) | 1994-01-19 |
| JPH05239041A (ja) | 1993-09-17 |
| NO924964D0 (no) | 1992-12-22 |
| TW211007B (enExample) | 1993-08-11 |
| HUT67788A (en) | 1995-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| RH1 | Patent not in force |