MX356584B - Analogos de tiazolidindiona para el tratamiento de enfermedad mediada por inflamacion metabolica. - Google Patents
Analogos de tiazolidindiona para el tratamiento de enfermedad mediada por inflamacion metabolica.Info
- Publication number
- MX356584B MX356584B MX2012009905A MX2012009905A MX356584B MX 356584 B MX356584 B MX 356584B MX 2012009905 A MX2012009905 A MX 2012009905A MX 2012009905 A MX2012009905 A MX 2012009905A MX 356584 B MX356584 B MX 356584B
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- mediated disease
- inflammation mediated
- metabolic inflammation
- thiazolidinedione analogues
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Transplantation (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La presente invención se refiere a análogos de tiazolidindiona que son útiles para el tratamiento de enfermedades mediadas por inflamación metabólica tal como diabetes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78289406P | 2006-03-16 | 2006-03-16 | |
PCT/US2007/006321 WO2007109024A2 (en) | 2006-03-16 | 2007-03-14 | Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease |
Publications (1)
Publication Number | Publication Date |
---|---|
MX356584B true MX356584B (es) | 2018-06-05 |
Family
ID=38328199
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012009905A MX356584B (es) | 2006-03-16 | 2007-03-14 | Analogos de tiazolidindiona para el tratamiento de enfermedad mediada por inflamacion metabolica. |
MX2008011871A MX2008011871A (es) | 2006-03-16 | 2007-03-14 | Analogos de tiazolidindiona para el tratamiento de enfermedad mediada por inflamacion metabolica. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008011871A MX2008011871A (es) | 2006-03-16 | 2007-03-14 | Analogos de tiazolidindiona para el tratamiento de enfermedad mediada por inflamacion metabolica. |
Country Status (15)
Country | Link |
---|---|
US (4) | US20090143442A1 (es) |
EP (3) | EP2902026B1 (es) |
JP (2) | JP5269758B2 (es) |
KR (1) | KR101475955B1 (es) |
CN (1) | CN101454005B (es) |
AU (1) | AU2007227581B2 (es) |
CA (1) | CA2646207C (es) |
ES (2) | ES2654908T3 (es) |
HU (1) | HUE035314T2 (es) |
MX (2) | MX356584B (es) |
NZ (1) | NZ571871A (es) |
PL (2) | PL2902026T3 (es) |
RU (1) | RU2445957C2 (es) |
UA (1) | UA96441C2 (es) |
WO (1) | WO2007109024A2 (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009530293A (ja) * | 2006-03-16 | 2009-08-27 | メタボリック ソリューションズ ディベロップメント カンパニー | チアゾリジンジオン類似体およびグルココルチコイドアゴニストの併用療法 |
EP2001469B1 (en) | 2006-03-16 | 2012-05-23 | Metabolic Solutions Development Company LLC | Thiazolidinedione analogues |
NZ571871A (en) | 2006-03-16 | 2011-07-29 | Metabolic Solutions Dev Co | Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease |
EP2203433B1 (en) | 2007-09-14 | 2012-10-31 | Metabolic Solutions Development Company LLC | 5-(4-(2-(3-methoxyphenyl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione for use in treating diabetes |
US8304441B2 (en) | 2007-09-14 | 2012-11-06 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues for the treatment of metabolic diseases |
US8722710B2 (en) | 2007-09-26 | 2014-05-13 | Deuterx, Llc | Deuterium-enriched pioglitazone |
CN102177436B (zh) | 2008-08-12 | 2015-05-13 | 金帆德尔制药股份有限公司 | 鉴定疾病风险因子的方法 |
US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
JP2013514368A (ja) * | 2009-12-15 | 2013-04-25 | メタボリック ソリューションズ ディベロップメント カンパニー, エルエルシー | 神経変性疾患を処置するための、ppar温存チアゾリジンジオンおよび組み合わせ物 |
MX2012006744A (es) * | 2009-12-15 | 2012-07-30 | Metabolic Solutions Dev Co Llc | Tiazolidinadionas reguladores de receptores activados por proliferador de peroxisoma (ppar) y combinaciones para el tratamiento de diabetes mellitus y otras enfermedades metabolicas. |
AU2014202074B2 (en) * | 2009-12-15 | 2016-01-07 | Cirius Therapeutics, Inc. | PPAR-sparing thiazolidinediones and combinations for the treatment of neurodegenerative diseases |
US8912335B2 (en) * | 2009-12-15 | 2014-12-16 | Metabolic Solutions Development Company, Llc | PPAR-sparing thiazolidinedione salts for the treatment of metabolic diseases |
GB2477743A (en) * | 2010-02-10 | 2011-08-17 | Argenta Therapeutics Ltd | Enantiomers of 5-methyl-thiazolidine-2,4-dione glitazone compounds |
GB201002224D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
MX2012012094A (es) * | 2010-04-19 | 2012-12-17 | Metabolic Solutions Dev Co Llc | Sintesis novedosa para compuestos de tiazolidinadiona. |
RU2012148908A (ru) | 2010-04-19 | 2014-05-27 | МЕТАБОЛИК СОЛЮШНЗ ДЕВЕЛОПМЕНТ КОМПАНИ, ЭлЭлСи | Новый синтез соединений тиазолидиндиона |
WO2012021467A1 (en) | 2010-08-10 | 2012-02-16 | Metabolic Solutions Development Company, Llc | Synthesis for thiazolidinedione compounds |
RU2593370C2 (ru) | 2010-08-10 | 2016-08-10 | Октета Терапьютикс, ЭлЭлСи | Новый способ синтеза соединений тиазолидиндиона |
MX355479B (es) | 2011-01-10 | 2018-04-19 | Zinfandel Pharmaceuticals Inc | Metodos y productos de farmaco para tratar enfermedad de alzheimer. |
WO2012114204A2 (en) * | 2011-02-15 | 2012-08-30 | Ecole Polytechnique Federale De Lausanne (Epfl) Epfl-Tto | Methods of treating mitochondrial dysfunction |
WO2012149083A1 (en) * | 2011-04-28 | 2012-11-01 | Metabolic Solutions Development Company, Llc | Ppar-sparing thiazolidinediones for the treatment of kidney related diseases |
KR20130015932A (ko) * | 2011-08-05 | 2013-02-14 | 연세대학교 산학협력단 | 저용량의 치아졸리딘다이온을 포함하는 알츠하이머 병 치료용 약학조성물 |
KR101501375B1 (ko) | 2012-09-21 | 2015-03-10 | 가톨릭대학교 산학협력단 | 메트포민을 유효성분으로 함유하는 염증성 장질환의 예방 또는 치료용 조성물 |
WO2014046474A2 (ko) * | 2012-09-21 | 2014-03-27 | 가톨릭대학교 산학협력단 | 메트포민을 유효성분으로 함유하는 염증성 장질환의 예방 또는 치료용 조성물 |
AU2013359903A1 (en) * | 2012-12-11 | 2015-07-02 | Cirius Therapeutics, Inc. | PPAR-sparing thiazolidinediones and combinations for the treatment of neurodegenerative diseases |
JP6800013B2 (ja) * | 2013-03-14 | 2020-12-16 | ポクセル・ソシエテ・アノニムPoxel SA | 重水素化2,4−チアゾリジンジオン及び治療方法 |
KR102349803B1 (ko) | 2013-07-22 | 2022-01-12 | 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 | 대사 질환의 치료를 위한 ppar-절약 화합물 |
EP3666273A3 (en) | 2014-01-15 | 2020-10-28 | Poxel SA | Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone |
EA035866B1 (ru) * | 2014-04-02 | 2020-08-21 | Минорикс Терапьютикс С.Л. | Применение производных 2,4-тиазолидиндиона для лечения расстройств центральной нервной системы и способ лечения с использованием таких производных |
BR112019011334A2 (pt) | 2016-12-01 | 2019-10-15 | Minoryx Therapeutics S L | uso de 5-[[4-[2-[5-(1-hidroxietil)piridin-2-il]etoxi]fenil]metil]-1,3-tiazolidina-2,4-diona e seus sais |
US11319313B2 (en) | 2020-06-30 | 2022-05-03 | Poxel Sa | Crystalline forms of deuterium-enriched pioglitazone |
US11767317B1 (en) | 2020-06-30 | 2023-09-26 | Poxel Sa | Methods of synthesizing enantiopure deuterium-enriched pioglitazone |
GB202210503D0 (en) | 2022-07-18 | 2022-08-31 | Univ Court Univ Of Glasgow | Materials and methods for treatment of chronic myeloid leukemia (CML) |
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JPS5522636A (en) | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
WO1985004170A1 (en) * | 1984-03-21 | 1985-09-26 | Takeda Chemical Industries, Ltd. | Thiazolidinedione derivatives, process for their preparation, and medicinal composition containing same |
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WO1986002073A1 (en) | 1984-10-03 | 1986-04-10 | Takeda Chemical Industries, Ltd. | Thiazolidinedione derivatives, process for their preparation, and pharmaceutical composition containing same |
CN1003445B (zh) * | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物,其制备方法和用途 |
AR240698A1 (es) * | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
US5167228A (en) * | 1987-06-26 | 1992-12-01 | Brigham And Women's Hospital | Assessment and modification of endogenous circadian phase and amplitude |
US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
US5441971A (en) * | 1991-04-11 | 1995-08-15 | The Upjohn Company | Thiazolidinedione derivatives, production and use thereof |
KR100249988B1 (ko) * | 1991-04-11 | 2000-04-01 | 로렌스 티. 마이젠헬더 | 티아졸리딘디온 유도체, 그의 제조방법 및 용도 |
NO302471B1 (no) | 1991-12-26 | 1998-03-09 | Sankyo Co | Tiazolidinforbindelser og farmasöytisk preparat |
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ATE376829T1 (de) * | 1993-09-15 | 2007-11-15 | Daiichi Sankyo Co Ltd | Verwendung von thiazolidindionen zur vorbeugung oder verzögerung des auftretens des nichtinsulinabhängigen diabetes mellitus (niddm) |
US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
TW438587B (en) | 1995-06-20 | 2001-06-07 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
NO318765B1 (no) | 1995-07-03 | 2005-05-02 | Sankyo Co | Anvendelse av en HMG-CoA reduktaseinhibitor og en insulinsensibilisator til fremstilling av et medikament for forebyggelse eller behandling av arteriosklerose eller xantom, samt pakket farmasoytisk preparat som omfatter de to midlene i separate porsjoner. |
GB0030845D0 (en) * | 2000-12-18 | 2001-01-31 | Smithkline Beecham Plc | Novel treatment |
EE200300519A (et) | 2001-04-26 | 2004-02-16 | L�civa, a.s. | Meetod pioglitasooni kui suhkurtõvevastase aine saamiseks |
JPWO2005054213A1 (ja) * | 2003-12-02 | 2007-12-06 | 塩野義製薬株式会社 | ペルオキシソーム増殖活性化受容体アゴニスト活性を有するイソキサゾール誘導体 |
NZ571871A (en) | 2006-03-16 | 2011-07-29 | Metabolic Solutions Dev Co | Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease |
EP2001469B1 (en) | 2006-03-16 | 2012-05-23 | Metabolic Solutions Development Company LLC | Thiazolidinedione analogues |
JP2009530293A (ja) * | 2006-03-16 | 2009-08-27 | メタボリック ソリューションズ ディベロップメント カンパニー | チアゾリジンジオン類似体およびグルココルチコイドアゴニストの併用療法 |
EP2203433B1 (en) | 2007-09-14 | 2012-10-31 | Metabolic Solutions Development Company LLC | 5-(4-(2-(3-methoxyphenyl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione for use in treating diabetes |
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2007
- 2007-03-14 NZ NZ571871A patent/NZ571871A/en not_active IP Right Cessation
- 2007-03-14 ES ES15151582.2T patent/ES2654908T3/es active Active
- 2007-03-14 MX MX2012009905A patent/MX356584B/es unknown
- 2007-03-14 AU AU2007227581A patent/AU2007227581B2/en not_active Ceased
- 2007-03-14 WO PCT/US2007/006321 patent/WO2007109024A2/en active Application Filing
- 2007-03-14 EP EP15151582.2A patent/EP2902026B1/en active Active
- 2007-03-14 UA UAA200812193A patent/UA96441C2/ru unknown
- 2007-03-14 MX MX2008011871A patent/MX2008011871A/es active IP Right Grant
- 2007-03-14 PL PL15151582T patent/PL2902026T3/pl unknown
- 2007-03-14 ES ES07752982T patent/ES2397944T3/es active Active
- 2007-03-14 PL PL07752982T patent/PL2001468T3/pl unknown
- 2007-03-14 RU RU2008140943/15A patent/RU2445957C2/ru active
- 2007-03-14 EP EP07752982A patent/EP2001468B1/en active Active
- 2007-03-14 HU HUE15151582A patent/HUE035314T2/en unknown
- 2007-03-14 CN CN2007800177654A patent/CN101454005B/zh active Active
- 2007-03-14 EP EP12166539A patent/EP2486926A1/en not_active Withdrawn
- 2007-03-14 JP JP2009500436A patent/JP5269758B2/ja not_active Expired - Fee Related
- 2007-03-14 CA CA2646207A patent/CA2646207C/en active Active
-
2008
- 2008-09-16 US US12/283,811 patent/US20090143442A1/en not_active Abandoned
- 2008-10-15 KR KR1020087025221A patent/KR101475955B1/ko active IP Right Grant
-
2011
- 2011-05-18 US US13/068,708 patent/US8389556B2/en active Active
-
2013
- 2013-01-28 US US13/751,672 patent/US20130203820A1/en not_active Abandoned
- 2013-03-01 JP JP2013040395A patent/JP2013100371A/ja active Pending
-
2014
- 2014-12-30 US US14/585,619 patent/US9155729B2/en not_active Expired - Fee Related
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