MX2008011872A - Analogos de tiazolidinediona para el tratamiento de la hipertension y para disminuir lipidos. - Google Patents
Analogos de tiazolidinediona para el tratamiento de la hipertension y para disminuir lipidos.Info
- Publication number
- MX2008011872A MX2008011872A MX2008011872A MX2008011872A MX2008011872A MX 2008011872 A MX2008011872 A MX 2008011872A MX 2008011872 A MX2008011872 A MX 2008011872A MX 2008011872 A MX2008011872 A MX 2008011872A MX 2008011872 A MX2008011872 A MX 2008011872A
- Authority
- MX
- Mexico
- Prior art keywords
- hypertension
- treatment
- lowering lipids
- thiazolidinedione analogues
- thiazolidinedione
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se relaciona con análogos de tiazolidinediona que son útiles para tratar la hipertensión.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78278706P | 2006-03-16 | 2006-03-16 | |
PCT/US2007/006385 WO2007109037A2 (en) | 2006-03-16 | 2007-03-14 | Thiazolidinedione analogues for the treatment of hypertension and for lowering lipids |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2008011872A true MX2008011872A (es) | 2009-02-10 |
Family
ID=38433001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2008011872A MX2008011872A (es) | 2006-03-16 | 2007-03-14 | Analogos de tiazolidinediona para el tratamiento de la hipertension y para disminuir lipidos. |
Country Status (11)
Country | Link |
---|---|
US (1) | US8629159B2 (es) |
EP (1) | EP2001469B1 (es) |
JP (2) | JP5149271B2 (es) |
CN (1) | CN101454006B (es) |
AU (1) | AU2007227594B2 (es) |
CA (1) | CA2646149A1 (es) |
ES (1) | ES2388555T3 (es) |
MX (1) | MX2008011872A (es) |
NZ (1) | NZ571870A (es) |
PL (1) | PL2001469T3 (es) |
WO (1) | WO2007109037A2 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2388555T3 (es) | 2006-03-16 | 2012-10-16 | Metabolic Solutions Development Company Llc | Análogos de tiazolidindiona |
WO2007109088A2 (en) * | 2006-03-16 | 2007-09-27 | Metabolic Solutions Development Company | Combinationtherapies of thiazolidinedione analogues and glucocorticoid agonists |
PL2902026T3 (pl) | 2006-03-16 | 2018-03-30 | Metabolic Solutions Development Company Llc | Analogi tiazolidynodionu do leczenia choroby metabolicznej pośredniczonej przez zapalenie |
US8304441B2 (en) | 2007-09-14 | 2012-11-06 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues for the treatment of metabolic diseases |
KR101537830B1 (ko) * | 2007-09-14 | 2015-07-17 | 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 | 고혈압 치료용 티아졸리딘디온 유사체 |
KR20120103711A (ko) * | 2009-12-15 | 2012-09-19 | 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 | 신경퇴행성 질환의 치료를 위한 ppar 절약형 티아졸리딘디온 및 복합제 |
WO2011084453A1 (en) | 2009-12-15 | 2011-07-14 | Metabolic Solutions Development Company | Ppar-sparing thiazolidinedione salts for the treatment of metabolic diseases |
CN103153972A (zh) * | 2010-04-19 | 2013-06-12 | 新陈代谢解决方案开发公司 | 噻唑烷二酮化合物的新的合成方法 |
DK2560956T3 (en) * | 2010-04-19 | 2017-01-23 | Octeta Therapeutics Llc | Hitherto UNKNOWN SYNTHESIS OF THIAZOLIDE INDION COMPOUNDS |
WO2012021476A1 (en) | 2010-08-10 | 2012-02-16 | Metabolic Solutions Development Company, Llc | Novel synthesis for thiazolidinedione compounds |
CN102370984B (zh) * | 2010-08-18 | 2015-04-08 | 天津金耀集团有限公司 | 以依普利酮和糖皮质激素为活性成分的吸入药物组合物 |
CN109400502A (zh) | 2013-07-22 | 2019-03-01 | 新陈代谢解决方案开发公司 | 用于治疗代谢疾病的ppar-节制性化合物 |
GB202210503D0 (en) | 2022-07-18 | 2022-08-31 | Univ Court Univ Of Glasgow | Materials and methods for treatment of chronic myeloid leukemia (CML) |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5522636A (en) | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
WO1985004170A1 (en) * | 1984-03-21 | 1985-09-26 | Takeda Chemical Industries, Ltd. | Thiazolidinedione derivatives, process for their preparation, and medicinal composition containing same |
US4582839A (en) * | 1984-03-21 | 1986-04-15 | Takeda Chemical Industries, Ltd. | 2,4-thiazolidinediones |
CN1003445B (zh) * | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物,其制备方法和用途 |
WO1986002073A1 (en) | 1984-10-03 | 1986-04-10 | Takeda Chemical Industries, Ltd. | Thiazolidinedione derivatives, process for their preparation, and pharmaceutical composition containing same |
AR240698A1 (es) * | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
US5167228A (en) * | 1987-06-26 | 1992-12-01 | Brigham And Women's Hospital | Assessment and modification of endogenous circadian phase and amplitude |
US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
US5356913A (en) * | 1990-02-09 | 1994-10-18 | The Upjohn Company | Use of insulin sensitizing agents to treat hypertension |
US5441971A (en) * | 1991-04-11 | 1995-08-15 | The Upjohn Company | Thiazolidinedione derivatives, production and use thereof |
CZ196693A3 (en) * | 1991-04-11 | 1994-05-18 | Upjohn Co | Thiazolidinedione derivatives, and process for preparing thereof |
NO302471B1 (no) | 1991-12-26 | 1998-03-09 | Sankyo Co | Tiazolidinforbindelser og farmasöytisk preparat |
US5716981A (en) * | 1993-07-19 | 1998-02-10 | Angiogenesis Technologies, Inc. | Anti-angiogenic compositions and methods of use |
US6099562A (en) * | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
NO318765B1 (no) * | 1995-07-03 | 2005-05-02 | Sankyo Co | Anvendelse av en HMG-CoA reduktaseinhibitor og en insulinsensibilisator til fremstilling av et medikament for forebyggelse eller behandling av arteriosklerose eller xantom, samt pakket farmasoytisk preparat som omfatter de to midlene i separate porsjoner. |
WO2002043807A2 (en) * | 2000-12-01 | 2002-06-06 | Novartis Ag | Combinations of an angiotensin receptor antagonist and an anti-hypertensive drug or a statin, for the treatment of sexual dysfunction |
AU2002311057A1 (en) | 2001-04-26 | 2002-11-11 | Leciva, A.S. | Method for obtaining pioglitazone as an antidiabetic agent |
AUPS236902A0 (en) * | 2002-05-16 | 2002-06-13 | Northern Sydney Area Health Service | Composition and method for treating hypertension |
ITFI20030058A1 (it) | 2003-03-06 | 2004-09-07 | Univ Firenze | Formulazioni farmaceutiche contenenti tiazolidinedioni |
PL2902026T3 (pl) | 2006-03-16 | 2018-03-30 | Metabolic Solutions Development Company Llc | Analogi tiazolidynodionu do leczenia choroby metabolicznej pośredniczonej przez zapalenie |
WO2007109088A2 (en) | 2006-03-16 | 2007-09-27 | Metabolic Solutions Development Company | Combinationtherapies of thiazolidinedione analogues and glucocorticoid agonists |
ES2388555T3 (es) | 2006-03-16 | 2012-10-16 | Metabolic Solutions Development Company Llc | Análogos de tiazolidindiona |
KR101537830B1 (ko) | 2007-09-14 | 2015-07-17 | 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 | 고혈압 치료용 티아졸리딘디온 유사체 |
-
2007
- 2007-03-14 ES ES07753040T patent/ES2388555T3/es active Active
- 2007-03-14 NZ NZ571870A patent/NZ571870A/en not_active IP Right Cessation
- 2007-03-14 JP JP2009500451A patent/JP5149271B2/ja not_active Expired - Fee Related
- 2007-03-14 PL PL07753040T patent/PL2001469T3/pl unknown
- 2007-03-14 MX MX2008011872A patent/MX2008011872A/es active IP Right Grant
- 2007-03-14 EP EP07753040A patent/EP2001469B1/en not_active Not-in-force
- 2007-03-14 WO PCT/US2007/006385 patent/WO2007109037A2/en active Application Filing
- 2007-03-14 CA CA002646149A patent/CA2646149A1/en not_active Abandoned
- 2007-03-14 AU AU2007227594A patent/AU2007227594B2/en not_active Ceased
- 2007-03-14 CN CN2007800178553A patent/CN101454006B/zh not_active Expired - Fee Related
-
2008
- 2008-09-16 US US12/283,812 patent/US8629159B2/en active Active
-
2012
- 2012-09-25 JP JP2012210905A patent/JP2012251001A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US8629159B2 (en) | 2014-01-14 |
EP2001469B1 (en) | 2012-05-23 |
JP5149271B2 (ja) | 2013-02-20 |
NZ571870A (en) | 2011-07-29 |
WO2007109037A2 (en) | 2007-09-27 |
EP2001469A2 (en) | 2008-12-17 |
CN101454006B (zh) | 2012-12-26 |
PL2001469T3 (pl) | 2012-10-31 |
JP2012251001A (ja) | 2012-12-20 |
AU2007227594A1 (en) | 2007-09-27 |
JP2009530286A (ja) | 2009-08-27 |
ES2388555T3 (es) | 2012-10-16 |
US20090137638A1 (en) | 2009-05-28 |
WO2007109037A3 (en) | 2007-11-08 |
CN101454006A (zh) | 2009-06-10 |
AU2007227594B2 (en) | 2012-11-15 |
CA2646149A1 (en) | 2007-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |