NZ245612A - Substituted thiazolidine derivatives; pharmaceutical compositions and preparatory processes - Google Patents

Substituted thiazolidine derivatives; pharmaceutical compositions and preparatory processes

Info

Publication number
NZ245612A
NZ245612A NZ245612A NZ24561292A NZ245612A NZ 245612 A NZ245612 A NZ 245612A NZ 245612 A NZ245612 A NZ 245612A NZ 24561292 A NZ24561292 A NZ 24561292A NZ 245612 A NZ245612 A NZ 245612A
Authority
NZ
New Zealand
Prior art keywords
compound
formula
group
thiazolidine
dione
Prior art date
Application number
NZ245612A
Other languages
English (en)
Inventor
Takao Yoshioka
Takahide Nishi
Tsutomu Kanai
Yuichi Aizawa
Kunio Wada
Takashi Fujita
Hiroyoshi Horikoshi
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NZ245612A publication Critical patent/NZ245612A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
NZ245612A 1991-12-26 1992-12-23 Substituted thiazolidine derivatives; pharmaceutical compositions and preparatory processes NZ245612A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34457191 1991-12-26

Publications (1)

Publication Number Publication Date
NZ245612A true NZ245612A (en) 1994-06-27

Family

ID=18370304

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ245612A NZ245612A (en) 1991-12-26 1992-12-23 Substituted thiazolidine derivatives; pharmaceutical compositions and preparatory processes

Country Status (21)

Country Link
EP (1) EP0549365B1 (enExample)
JP (1) JP2833949B2 (enExample)
CN (1) CN1032751C (enExample)
AT (1) ATE126221T1 (enExample)
AU (1) AU654223B2 (enExample)
CA (1) CA2086277A1 (enExample)
CZ (1) CZ389792A3 (enExample)
DE (1) DE69204041T2 (enExample)
DK (1) DK0549365T3 (enExample)
ES (1) ES2078671T3 (enExample)
FI (1) FI925849A7 (enExample)
GR (1) GR3017632T3 (enExample)
HK (1) HK196095A (enExample)
HU (1) HU215450B (enExample)
IL (1) IL104238A (enExample)
MX (1) MX9207595A (enExample)
NO (1) NO302471B1 (enExample)
NZ (1) NZ245612A (enExample)
RU (1) RU2095354C1 (enExample)
TW (1) TW211007B (enExample)
ZA (1) ZA9210021B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
CA2146701A1 (en) * 1994-04-11 1995-10-12 Takashi Fujita Heterocyclic compounds having anti-diabetic activity, their preparation and their use
EP0783888A1 (en) 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
US6331633B1 (en) * 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
DE19828114A1 (de) * 1998-06-24 2000-01-27 Probiodrug Ges Fuer Arzneim Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
DE19828113A1 (de) * 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
DE19926233C1 (de) * 1999-06-10 2000-10-19 Probiodrug Ges Fuer Arzneim Verfahren zur Herstellung von Thiazolidin
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
ES2248242T3 (es) * 2000-04-21 2006-03-16 Pfizer Products Inc. Ligandos de receptores tiroideos.
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
JP2003531200A (ja) * 2000-04-24 2003-10-21 アリックス セラピューティクス 糖尿病、高脂血症、高コレステロール血症、およびアテローム性動脈硬化症の治療のための材料と方法
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法
CN101454006B (zh) 2006-03-16 2012-12-26 新陈代谢解决方案开发公司 用于治疗高血压以及用于降低血脂的噻唑烷二酮类似物
ES2654908T3 (es) 2006-03-16 2018-02-15 Metabolic Solutions Development Company Llc Análogos de tiazolidindiona para el tratamiento de enfermedades mediadas por una inflamación metabólica
PL2203433T3 (pl) * 2007-09-14 2013-04-30 Metabolic Solutions Dev Co Llc 5-(4-(2-(3-metoksyfenylo)-2-oksoetoksy)benzylo)tiazolidyno-2,4-dion do stosowania w leczeniu cukrzycy
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
US8912335B2 (en) 2009-12-15 2014-12-16 Metabolic Solutions Development Company, Llc PPAR-sparing thiazolidinedione salts for the treatment of metabolic diseases
EP2560956B1 (en) * 2010-04-19 2016-10-26 Octeta Therapeutics, LLC Novel synthesis for thiazolidinedione compounds
CN102946860A (zh) * 2010-04-21 2013-02-27 新陈代谢解决方案开发公司 噻唑烷二酮类似物
RU2593370C2 (ru) 2010-08-10 2016-08-10 Октета Терапьютикс, ЭлЭлСи Новый способ синтеза соединений тиазолидиндиона
CN115433144B (zh) * 2022-10-09 2023-09-19 燃点(南京)生物医药科技有限公司 一种脂肪酸酯类化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat

Also Published As

Publication number Publication date
ATE126221T1 (de) 1995-08-15
HUT67788A (en) 1995-04-28
FI925849A7 (fi) 1993-06-27
CN1074680A (zh) 1993-07-28
JPH05239041A (ja) 1993-09-17
NO924964L (no) 1993-06-28
RU2095354C1 (ru) 1997-11-10
EP0549365B1 (en) 1995-08-09
TW211007B (enExample) 1993-08-11
MX9207595A (es) 1994-06-30
NO302471B1 (no) 1998-03-09
NO924964D0 (no) 1992-12-22
AU3043192A (en) 1993-07-01
CN1032751C (zh) 1996-09-11
IL104238A (en) 1996-10-31
EP0549365A1 (en) 1993-06-30
DE69204041D1 (de) 1995-09-14
ZA9210021B (en) 1993-07-02
HK196095A (en) 1996-01-05
JP2833949B2 (ja) 1998-12-09
GR3017632T3 (en) 1996-01-31
HU215450B (hu) 1999-04-28
ES2078671T3 (es) 1995-12-16
DE69204041T2 (de) 1996-03-28
FI925849A0 (fi) 1992-12-23
AU654223B2 (en) 1994-10-27
DK0549365T3 (da) 1995-12-18
HU9204130D0 (en) 1993-04-28
CA2086277A1 (en) 1993-06-27
CZ389792A3 (en) 1994-01-19

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