DK0549365T3 - Thiazolidinforbindelser, deres fremstilling og deres terapeutiske anvendelser - Google Patents

Thiazolidinforbindelser, deres fremstilling og deres terapeutiske anvendelser

Info

Publication number
DK0549365T3
DK0549365T3 DK92311813.7T DK92311813T DK0549365T3 DK 0549365 T3 DK0549365 T3 DK 0549365T3 DK 92311813 T DK92311813 T DK 92311813T DK 0549365 T3 DK0549365 T3 DK 0549365T3
Authority
DK
Denmark
Prior art keywords
alkyl
hydrogen
preparation
therapeutic uses
optionally substituted
Prior art date
Application number
DK92311813.7T
Other languages
English (en)
Inventor
Takao Yoshioka
Takahide Nishi
Tsutomu Kanai
Yuichi Aizawa
Kunio Wada
Takashi Fujita
Hiroyoshi Horikoshi
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of DK0549365T3 publication Critical patent/DK0549365T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK92311813.7T 1991-12-26 1992-12-24 Thiazolidinforbindelser, deres fremstilling og deres terapeutiske anvendelser DK0549365T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34457191 1991-12-26

Publications (1)

Publication Number Publication Date
DK0549365T3 true DK0549365T3 (da) 1995-12-18

Family

ID=18370304

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92311813.7T DK0549365T3 (da) 1991-12-26 1992-12-24 Thiazolidinforbindelser, deres fremstilling og deres terapeutiske anvendelser

Country Status (21)

Country Link
EP (1) EP0549365B1 (da)
JP (1) JP2833949B2 (da)
CN (1) CN1032751C (da)
AT (1) ATE126221T1 (da)
AU (1) AU654223B2 (da)
CA (1) CA2086277A1 (da)
CZ (1) CZ389792A3 (da)
DE (1) DE69204041T2 (da)
DK (1) DK0549365T3 (da)
ES (1) ES2078671T3 (da)
FI (1) FI925849A (da)
GR (1) GR3017632T3 (da)
HK (1) HK196095A (da)
HU (1) HU215450B (da)
IL (1) IL104238A (da)
MX (1) MX9207595A (da)
NO (1) NO302471B1 (da)
NZ (1) NZ245612A (da)
RU (1) RU2095354C1 (da)
TW (1) TW211007B (da)
ZA (1) ZA9210021B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat
EP0783888A1 (en) * 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
US6331633B1 (en) * 1998-05-08 2001-12-18 Calyx Therapeutics Inc. Heterocyclic analogs of diphenylethylene compounds
US6620830B2 (en) 2000-04-21 2003-09-16 Pfizer, Inc. Thyroid receptor ligands
ATE310733T1 (de) * 2000-04-21 2005-12-15 Pfizer Prod Inc Thyroid-rezeptorliganden
EP1276730A2 (en) * 2000-04-24 2003-01-22 ARYx Therapeutics Thiazolidinedione analogues and their use for the treatment of diabetes
US6768008B2 (en) 2000-04-24 2004-07-27 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
US6680387B2 (en) 2000-04-24 2004-01-20 Aryx Therapeutics Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd ５−［６−（２−フルオロベンジルオキシ）−２−ナフチル］メチル−２，４−チアゾリジンジオンの製造方法及びその精製方法
NZ571871A (en) 2006-03-16 2011-07-29 Metabolic Solutions Dev Co Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease
CN101454006B (zh) 2006-03-16 2012-12-26 新陈代谢解决方案开发公司 用于治疗高血压以及用于降低血脂的噻唑烷二酮类似物
WO2009038681A1 (en) * 2007-09-14 2009-03-26 Metabolic Solutions Development Company Thiazolidinedione analogues for the treatment of hypertension
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
CN102753539B (zh) 2009-12-15 2015-09-09 新陈代谢解决方案开发公司 治疗代谢性疾病的ppar-节制的噻唑烷二酮盐
NZ602883A (en) * 2010-04-19 2014-09-26 Metabolic Solutions Dev Co Llc Novel synthesis for thiazolidinedione compounds
US20130281414A1 (en) * 2010-04-21 2013-10-24 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues
CN103180304B (zh) 2010-08-10 2017-02-15 奥克泰塔治疗有限责任公司 噻唑烷二酮化合物的合成方法
CN115433144B (zh) * 2022-10-09 2023-09-19 燃点(南京)生物医药科技有限公司 一种脂肪酸酯类化合物及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
JPH06779B2 (ja) * 1985-06-10 1994-01-05 武田薬品工業株式会社 チアゾリジオン誘導体およびそれを含んでなる医薬組成物
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
NO302519B1 (no) * 1991-12-26 1998-03-16 Sankyo Co Tiazolidinforbindelser som inneholder en kinongruppe, og farmasöytisk preparat

Also Published As

Publication number Publication date
AU654223B2 (en) 1994-10-27
EP0549365A1 (en) 1993-06-30
ZA9210021B (en) 1993-07-02
CN1074680A (zh) 1993-07-28
NO924964L (no) 1993-06-28
EP0549365B1 (en) 1995-08-09
NO302471B1 (no) 1998-03-09
ES2078671T3 (es) 1995-12-16
IL104238A (en) 1996-10-31
MX9207595A (es) 1994-06-30
RU2095354C1 (ru) 1997-11-10
HK196095A (en) 1996-01-05
JP2833949B2 (ja) 1998-12-09
DE69204041T2 (de) 1996-03-28
TW211007B (da) 1993-08-11
ATE126221T1 (de) 1995-08-15
HU215450B (hu) 1999-04-28
DE69204041D1 (de) 1995-09-14
CA2086277A1 (en) 1993-06-27
GR3017632T3 (en) 1996-01-31
HUT67788A (en) 1995-04-28
FI925849A (fi) 1993-06-27
HU9204130D0 (en) 1993-04-28
FI925849A0 (fi) 1992-12-23
JPH05239041A (ja) 1993-09-17
NZ245612A (en) 1994-06-27
NO924964D0 (no) 1992-12-22
CN1032751C (zh) 1996-09-11
CZ389792A3 (en) 1994-01-19
AU3043192A (en) 1993-07-01

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