RU92016230A - Тиазолидиновые соединения, фармацевтическая композиция, способ лечения и способы получения соединений - Google Patents
Тиазолидиновые соединения, фармацевтическая композиция, способ лечения и способы получения соединенийInfo
- Publication number
- RU92016230A RU92016230A RU92016230/33A RU92016230A RU92016230A RU 92016230 A RU92016230 A RU 92016230A RU 92016230/33 A RU92016230/33 A RU 92016230/33A RU 92016230 A RU92016230 A RU 92016230A RU 92016230 A RU92016230 A RU 92016230A
- Authority
- RU
- Russia
- Prior art keywords
- compounds
- methods
- pharmaceutical composition
- treatment method
- thiazolidine
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003548 thiazolidines Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 230000003178 anti-diabetic Effects 0.000 claims 1
- 239000011203 carbon fibre reinforced carbon Substances 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 230000001225 therapeutic Effects 0.000 claims 1
Claims (1)
- Соединение общей формулы
где R1 - алкил; R2 и R3 - каждый алкил или алкокси или R2 и R3 вместе образуют необязательно замещенное бензольное кольцо и когда R2 и R3 вместе образуют указанное бензольное кольцо, то R1 - водород, галоген или алкил; R4 и R5 - оба водород или вместе одинарная углерод-углеродная связь; W - одинарная связь или алкилен; Z - водород или катион, обладает ценными видами терапевтической и профилактической активности, включая противодиабетическую активность.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3-344570 | 1991-12-26 | ||
| JP34457091 | 1991-12-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU92016230A true RU92016230A (ru) | 1995-06-19 |
| RU2103265C1 RU2103265C1 (ru) | 1998-01-27 |
Family
ID=18370296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU92016230A RU2103265C1 (ru) | 1991-12-26 | 1992-12-25 | Производные тиазолидин-2,4-диона и способ их получения |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5338855A (ru) |
| EP (1) | EP0549366B1 (ru) |
| JP (1) | JP2833948B2 (ru) |
| KR (1) | KR100198183B1 (ru) |
| CN (1) | CN1033639C (ru) |
| AT (1) | ATE165092T1 (ru) |
| AU (1) | AU654222B2 (ru) |
| CA (1) | CA2086179C (ru) |
| CZ (1) | CZ279917B6 (ru) |
| DE (1) | DE69225123T2 (ru) |
| DK (1) | DK0549366T3 (ru) |
| ES (1) | ES2115650T3 (ru) |
| FI (1) | FI925848A (ru) |
| GR (1) | GR3026656T3 (ru) |
| HK (1) | HK1007050A1 (ru) |
| HU (1) | HU215448B (ru) |
| IL (1) | IL104237A (ru) |
| MX (1) | MX9207594A (ru) |
| NO (1) | NO302519B1 (ru) |
| NZ (1) | NZ245611A (ru) |
| RU (1) | RU2103265C1 (ru) |
| TW (1) | TW211008B (ru) |
| ZA (1) | ZA9210020B (ru) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO302471B1 (no) * | 1991-12-26 | 1998-03-09 | Sankyo Co | Tiazolidinforbindelser og farmasöytisk preparat |
| NO305987B1 (no) * | 1994-04-11 | 1999-08-30 | Sankyo Co | Heterosykliske forbindelser med antidiabetisk aktivitet, deres anvendelse og farmasoeytisk preparat inneholdende disse |
| IL118474A (en) * | 1995-06-01 | 2001-08-08 | Sankyo Co | Benzimideol derivatives and pharmaceutical preparations containing them |
| US6147101A (en) * | 1995-06-02 | 2000-11-14 | Kyorin Pharmaceutical Co., Ltd. | N-benzyldioxothiazolidylbenzamide derivatives and process for producing the same |
| US6001862A (en) * | 1995-06-02 | 1999-12-14 | Kyorin Pharameuticals Co., Ltd. | N-benzyldioxothiazolidylbenzamide derivatives and processes for preparing the same |
| JP3144624B2 (ja) * | 1995-06-02 | 2001-03-12 | 杏林製薬株式会社 | Ｎ−ベンジルジオキソチアゾリジルベンズアミド誘導体及びその製造法 |
| EP0783888A1 (en) | 1995-12-26 | 1997-07-16 | Sankyo Company Limited | Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis |
| JPH10338679A (ja) * | 1997-04-08 | 1998-12-22 | Mitsubishi Rayon Co Ltd | チアゾリジン誘導体の製造方法 |
| US6414123B1 (en) * | 1997-10-21 | 2002-07-02 | Vitro Diagnostics, Inc. | Method for purifying FSH |
| US6077849A (en) * | 1998-04-02 | 2000-06-20 | Merck & Co., Inc. | Antidiabetic agents |
| US6028088A (en) * | 1998-10-30 | 2000-02-22 | The University Of Mississippi | Flavonoid derivatives |
| US6204288B1 (en) | 1999-03-08 | 2001-03-20 | The University Of Mississippi | 1,2-dithiolane derivatives |
| US6127394A (en) * | 1999-03-08 | 2000-10-03 | The University Of Mississippi | 1,2-Dithiolane derivatives |
| US6818776B2 (en) | 2000-02-01 | 2004-11-16 | Kyorin Pharmaceutical Co., Ltd. | Alkali metal salt of thiazolidine-2,4-dione derivative |
| US7888334B2 (en) | 2003-08-22 | 2011-02-15 | Antipodean Pharmaceuticals, Inc. | Mitoquinone derivatives used as mitochondrially targeted antioxidants |
| US7888335B2 (en) | 2003-08-22 | 2011-02-15 | Antipodean Pharmaceuticals, Inc. | Mitoquinone derivatives used as mitochondrially targeted antioxidants |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4725010A (en) * | 1986-07-18 | 1988-02-16 | Essex Group, Inc. | Control apparatus and method |
| JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
| US5120754A (en) * | 1988-03-08 | 1992-06-09 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
| US5130379A (en) * | 1988-03-08 | 1992-07-14 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| GB8910639D0 (en) * | 1989-05-09 | 1989-06-21 | Beecham Group Plc | Novel compounds |
| GB8919434D0 (en) * | 1989-08-25 | 1989-10-11 | Beecham Group Plc | Novel compounds |
| US5143930A (en) * | 1990-02-07 | 1992-09-01 | Sankyo Company, Limited | Thiazolidine derivatives with anti-diabetic activity, their preparation and their use |
| NO302471B1 (no) * | 1991-12-26 | 1998-03-09 | Sankyo Co | Tiazolidinforbindelser og farmasöytisk preparat |
-
1992
- 1992-12-22 NO NO924988A patent/NO302519B1/no not_active IP Right Cessation
- 1992-12-23 CA CA002086179A patent/CA2086179C/en not_active Expired - Fee Related
- 1992-12-23 HU HUP9204121A patent/HU215448B/hu not_active IP Right Cessation
- 1992-12-23 ZA ZA9210020A patent/ZA9210020B/xx unknown
- 1992-12-23 NZ NZ245611A patent/NZ245611A/en unknown
- 1992-12-23 FI FI925848A patent/FI925848A/fi unknown
- 1992-12-24 KR KR1019920025528A patent/KR100198183B1/ko not_active IP Right Cessation
- 1992-12-24 AT AT92311814T patent/ATE165092T1/de not_active IP Right Cessation
- 1992-12-24 DK DK92311814T patent/DK0549366T3/da active
- 1992-12-24 DE DE69225123T patent/DE69225123T2/de not_active Expired - Fee Related
- 1992-12-24 AU AU30429/92A patent/AU654222B2/en not_active Ceased
- 1992-12-24 EP EP92311814A patent/EP0549366B1/en not_active Expired - Lifetime
- 1992-12-24 ES ES92311814T patent/ES2115650T3/es not_active Expired - Lifetime
- 1992-12-24 TW TW081110380A patent/TW211008B/zh active
- 1992-12-25 RU RU92016230A patent/RU2103265C1/ru active
- 1992-12-25 IL IL10423792A patent/IL104237A/en not_active IP Right Cessation
- 1992-12-25 JP JP4346121A patent/JP2833948B2/ja not_active Expired - Fee Related
- 1992-12-26 CN CN92113835A patent/CN1033639C/zh not_active Expired - Fee Related
- 1992-12-28 CZ CS923896A patent/CZ279917B6/cs not_active IP Right Cessation
- 1992-12-28 US US07/997,210 patent/US5338855A/en not_active Expired - Fee Related
- 1992-12-28 MX MX9207594A patent/MX9207594A/es not_active IP Right Cessation
-
1998
- 1998-04-15 GR GR980400859T patent/GR3026656T3/el unknown
- 1998-06-23 HK HK98106107A patent/HK1007050A1/xx not_active IP Right Cessation
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