RU2017121096A - Комбинированная терапия, включающая применение ох40-связывающих агонистов и антагонистов связывания оси pd-1 - Google Patents
Комбинированная терапия, включающая применение ох40-связывающих агонистов и антагонистов связывания оси pd-1 Download PDFInfo
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Classifications
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462080991P | 2014-11-17 | 2014-11-17 | |
| US62/080,991 | 2014-11-17 | ||
| US201462093400P | 2014-12-17 | 2014-12-17 | |
| US62/093,400 | 2014-12-17 | ||
| PCT/US2015/060941 WO2016081384A1 (en) | 2014-11-17 | 2015-11-16 | Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2017121096A true RU2017121096A (ru) | 2018-12-19 |
| RU2017121096A3 RU2017121096A3 (OSRAM) | 2019-10-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017121096A RU2017121096A (ru) | 2014-11-17 | 2015-11-16 | Комбинированная терапия, включающая применение ох40-связывающих агонистов и антагонистов связывания оси pd-1 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20160166685A1 (OSRAM) |
| EP (1) | EP3221360A1 (OSRAM) |
| JP (1) | JP2017537090A (OSRAM) |
| KR (1) | KR20170096112A (OSRAM) |
| CN (1) | CN106999583A (OSRAM) |
| AU (1) | AU2015350242A1 (OSRAM) |
| BR (1) | BR112017010198A2 (OSRAM) |
| CA (1) | CA2967368A1 (OSRAM) |
| IL (1) | IL252251A0 (OSRAM) |
| MX (1) | MX2017006320A (OSRAM) |
| RU (1) | RU2017121096A (OSRAM) |
| SG (2) | SG11201703605QA (OSRAM) |
| WO (1) | WO2016081384A1 (OSRAM) |
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| HRP20170908T1 (hr) | 2008-12-09 | 2017-09-22 | F. Hoffmann - La Roche Ag | Protutijela anti-pd-l1 i njihova uporaba za poboljšanje funkcije t-stanice |
| UA119319C2 (uk) | 2013-03-18 | 2019-06-10 | Біосерокс Продактс Б.В. | Гуманізоване антитіло до cd134 (ox40) і його застосування |
| AR097584A1 (es) | 2013-09-12 | 2016-03-23 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano |
| SG11201604738TA (en) | 2013-12-12 | 2016-07-28 | Shanghai Hengrui Pharm Co Ltd | Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof |
| CA2943834A1 (en) | 2014-03-31 | 2015-10-08 | Genentech, Inc. | Combination therapy comprising anti-angiogenesis agents and ox40 binding agonists |
| BR112017009151A2 (pt) | 2014-11-03 | 2018-03-06 | Genentech, Inc. | ensaios para detectar subgrupos imunológicos de célula t e métodos de uso dos mesmos |
| WO2016073380A1 (en) | 2014-11-03 | 2016-05-12 | Genentech, Inc. | Method and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment |
| MA41414A (fr) * | 2015-01-28 | 2017-12-05 | Centre Nat Rech Scient | Protéines de liaison agonistes d' icos |
| BR112017018234A2 (pt) | 2015-02-26 | 2018-04-17 | Merck Patent Gmbh | inibidores de pd-1 / pd-l1 para o tratamento de câncer |
| GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| JP6797137B2 (ja) | 2015-05-29 | 2020-12-09 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Ｏｘ４０に対する抗体およびその使用 |
| MX2017015937A (es) * | 2015-06-08 | 2018-12-11 | Genentech Inc | Métodos de tratamiento del cáncer con anticuerpos anti-ox40 y antagonistas de unión al eje de pd-1. |
| KR102712880B1 (ko) | 2015-06-16 | 2024-10-02 | 메르크 파텐트 게엠베하 | Pd-l1 길항제 조합 치료 |
| JP7014706B2 (ja) | 2015-07-13 | 2022-02-01 | サイトメックス セラピューティクス インコーポレイテッド | 抗ｐｄ－１抗体、活性化可能抗ｐｄ－１抗体、およびその使用方法 |
| IL316210A (en) | 2015-10-01 | 2024-12-01 | Heat Biologics Inc | Compounds and methods for connecting type 1 and 2 extracellular complexes as heterologous chimeric proteins |
| AU2016329120B2 (en) | 2015-10-02 | 2023-04-13 | F. Hoffmann-La Roche Ag | Bispecific antibodies specific for a costimulatory TNF receptor |
| AU2017205089B2 (en) | 2016-01-08 | 2023-10-05 | F. Hoffmann-La Roche Ag | Methods of treating CEA-positive cancers using PD-1 axis binding antagonists and anti-CEA/anti-CD3 bispecific antibodies |
| JP7328761B2 (ja) * | 2016-01-11 | 2023-08-17 | インヒブルクス インコーポレイテッド | 多価多重特異性ｏｘ４０結合融合タンパク質 |
| SG10201912405TA (en) | 2016-01-11 | 2020-02-27 | Inhibrx Inc | Multivalent and multispecific 41bb-binding fusion proteins |
| TWI808055B (zh) * | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| WO2017210624A1 (en) * | 2016-06-03 | 2017-12-07 | Bristol-Myers Squibb Company | Anti-pd-1 antibody for use in a method of treating a tumor |
| WO2018014260A1 (en) * | 2016-07-20 | 2018-01-25 | Nanjing Legend Biotech Co., Ltd. | Multispecific antigen binding proteins and methods of use thereof |
| EP3494139B1 (en) | 2016-08-05 | 2022-01-12 | F. Hoffmann-La Roche AG | Multivalent and multiepitopic anitibodies having agonistic activity and methods of use |
| JP7138094B2 (ja) | 2016-08-25 | 2022-09-15 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | マクロファージ活性化剤と組み合わせた抗ｃｓｆ－１ｒ抗体の間欠投与 |
| MX2019003755A (es) | 2016-10-06 | 2019-08-12 | Pfizer | Regimen de dosificacion de avelumab para el tratamiento de cancer. |
| WO2018068201A1 (en) | 2016-10-11 | 2018-04-19 | Nanjing Legend Biotech Co., Ltd. | Single-domain antibodies and variants thereof against ctla-4 |
| JP7304287B2 (ja) * | 2016-12-22 | 2023-07-06 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | 抗ｐｄ－ｌ１／ｐｄ１治療の不成功後の、抗ｐｄ－ｌ１抗体との組み合わせでの抗ｃｓｆ－１ｒ抗体を用いた腫瘍の治療 |
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-
2015
- 2015-11-16 KR KR1020177016253A patent/KR20170096112A/ko not_active Withdrawn
- 2015-11-16 SG SG11201703605QA patent/SG11201703605QA/en unknown
- 2015-11-16 MX MX2017006320A patent/MX2017006320A/es unknown
- 2015-11-16 WO PCT/US2015/060941 patent/WO2016081384A1/en not_active Ceased
- 2015-11-16 SG SG10201807625PA patent/SG10201807625PA/en unknown
- 2015-11-16 AU AU2015350242A patent/AU2015350242A1/en not_active Abandoned
- 2015-11-16 JP JP2017526558A patent/JP2017537090A/ja active Pending
- 2015-11-16 BR BR112017010198A patent/BR112017010198A2/pt not_active IP Right Cessation
- 2015-11-16 EP EP15802289.7A patent/EP3221360A1/en not_active Withdrawn
- 2015-11-16 CA CA2967368A patent/CA2967368A1/en not_active Abandoned
- 2015-11-16 CN CN201580061883.XA patent/CN106999583A/zh active Pending
- 2015-11-16 RU RU2017121096A patent/RU2017121096A/ru unknown
- 2015-11-16 US US14/942,896 patent/US20160166685A1/en not_active Abandoned
-
2017
- 2017-05-11 IL IL252251A patent/IL252251A0/en unknown
- 2017-06-16 US US15/625,572 patent/US20170290913A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL252251A0 (en) | 2017-07-31 |
| SG11201703605QA (en) | 2017-06-29 |
| WO2016081384A1 (en) | 2016-05-26 |
| US20160166685A1 (en) | 2016-06-16 |
| US20170290913A1 (en) | 2017-10-12 |
| SG10201807625PA (en) | 2018-10-30 |
| AU2015350242A1 (en) | 2017-06-29 |
| CA2967368A1 (en) | 2016-05-26 |
| KR20170096112A (ko) | 2017-08-23 |
| MX2017006320A (es) | 2017-08-10 |
| EP3221360A1 (en) | 2017-09-27 |
| RU2017121096A3 (OSRAM) | 2019-10-17 |
| JP2017537090A (ja) | 2017-12-14 |
| CN106999583A (zh) | 2017-08-01 |
| BR112017010198A2 (pt) | 2017-12-26 |
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