RU2017121096A - Комбинированная терапия, включающая применение ох40-связывающих агонистов и антагонистов связывания оси pd-1 - Google Patents
Комбинированная терапия, включающая применение ох40-связывающих агонистов и антагонистов связывания оси pd-1 Download PDFInfo
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462080991P | 2014-11-17 | 2014-11-17 | |
| US62/080,991 | 2014-11-17 | ||
| US201462093400P | 2014-12-17 | 2014-12-17 | |
| US62/093,400 | 2014-12-17 | ||
| PCT/US2015/060941 WO2016081384A1 (en) | 2014-11-17 | 2015-11-16 | Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2017121096A true RU2017121096A (ru) | 2018-12-19 |
| RU2017121096A3 RU2017121096A3 (OSRAM) | 2019-10-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017121096A RU2017121096A (ru) | 2014-11-17 | 2015-11-16 | Комбинированная терапия, включающая применение ох40-связывающих агонистов и антагонистов связывания оси pd-1 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20160166685A1 (OSRAM) |
| EP (1) | EP3221360A1 (OSRAM) |
| JP (1) | JP2017537090A (OSRAM) |
| KR (1) | KR20170096112A (OSRAM) |
| CN (1) | CN106999583A (OSRAM) |
| AU (1) | AU2015350242A1 (OSRAM) |
| BR (1) | BR112017010198A2 (OSRAM) |
| CA (1) | CA2967368A1 (OSRAM) |
| IL (1) | IL252251A0 (OSRAM) |
| MX (1) | MX2017006320A (OSRAM) |
| RU (1) | RU2017121096A (OSRAM) |
| SG (2) | SG10201807625PA (OSRAM) |
| WO (1) | WO2016081384A1 (OSRAM) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8217149B2 (en) | 2008-12-09 | 2012-07-10 | Genentech, Inc. | Anti-PD-L1 antibodies, compositions and articles of manufacture |
| EA201591495A1 (ru) | 2013-03-18 | 2016-05-31 | Биосерокс Продактс Б.В. | Гуманизированные антитела против cd134 (ox40) и применения указанных антител |
| AR097584A1 (es) | 2013-09-12 | 2016-03-23 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano |
| CR20160319A (es) | 2013-12-12 | 2016-11-08 | Jiangsu Hengrui Medicine Co | Anticuerpo pd-1, fragmento de union al antigeno de este y uso médico de este |
| JP6588461B2 (ja) | 2014-03-31 | 2019-10-09 | ジェネンテック， インコーポレイテッド | 抗血管新生剤及びｏｘ４０結合アゴニストを含む併用療法 |
| CA2966523A1 (en) | 2014-11-03 | 2016-05-12 | Genentech, Inc. | Assays for detecting t cell immune subsets and methods of use thereof |
| SG11201703521UA (en) | 2014-11-03 | 2017-05-30 | Genentech Inc | Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment |
| MA41414A (fr) * | 2015-01-28 | 2017-12-05 | Centre Nat Rech Scient | Protéines de liaison agonistes d' icos |
| SG10201810615VA (en) | 2015-02-26 | 2019-01-30 | Merck Patent Gmbh | Pd-1 / pd-l1 inhibitors for the treatment of cancer |
| GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| UY36687A (es) | 2015-05-29 | 2016-11-30 | Bristol Myers Squibb Company Una Corporación Del Estado De Delaware | Anticuerpos contra ox40 y sus usos |
| JP2018518483A (ja) * | 2015-06-08 | 2018-07-12 | ジェネンテック， インコーポレイテッド | 抗ｏｘ４０抗体及びｐｄ−１軸結合アンタゴニストを使用して癌を治療する方法 |
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| RU2766200C1 (ru) | 2015-10-01 | 2022-02-09 | Хит Байолоджикс, Инк. | Композиции и способы для соединения внеклеточных доменов типа i и типа ii в качестве гетерологичных химерных белков |
| KR20180053674A (ko) | 2015-10-02 | 2018-05-23 | 에프. 호프만-라 로슈 아게 | 공자극 tnf 수용체에 특이적인 이중특이성 항체 |
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| US20170198051A1 (en) * | 2016-01-11 | 2017-07-13 | Inhibrx Lp | Multivalent and multispecific ox40-binding fusion proteins |
| SG10201912405TA (en) | 2016-01-11 | 2020-02-27 | Inhibrx Inc | Multivalent and multispecific 41bb-binding fusion proteins |
| TWI808055B (zh) * | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| CN109476753A (zh) * | 2016-06-03 | 2019-03-15 | 百时美施贵宝公司 | 用于治疗肿瘤的方法的抗-pd-1抗体 |
| WO2018014260A1 (en) * | 2016-07-20 | 2018-01-25 | Nanjing Legend Biotech Co., Ltd. | Multispecific antigen binding proteins and methods of use thereof |
| JP2019530434A (ja) | 2016-08-05 | 2019-10-24 | ジェネンテック， インコーポレイテッド | アゴニスト活性を有する多価及び多重エピトープ抗体ならびに使用方法 |
| WO2018036852A1 (en) | 2016-08-25 | 2018-03-01 | F. Hoffmann-La Roche Ag | Intermittent dosing of an anti-csf-1r antibody in combination with macrophage activating agent |
| IL265762B2 (en) | 2016-10-06 | 2024-04-01 | Merck Patent Gmbh | Dosing regimen of avelumab for the treatment of cancer |
| WO2018068201A1 (en) | 2016-10-11 | 2018-04-19 | Nanjing Legend Biotech Co., Ltd. | Single-domain antibodies and variants thereof against ctla-4 |
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| JP2021501801A (ja) * | 2017-11-01 | 2021-01-21 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | 癌の処置に用いるための免疫刺激アゴニスト抗体 |
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| TWI864129B (zh) | 2017-12-29 | 2024-12-01 | 圓祥生技股份有限公司 | 調節免疫檢查點作為癌症治療的單特異性蛋白質、其醫藥組成物、其核酸、及其用途 |
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-
2015
- 2015-11-16 EP EP15802289.7A patent/EP3221360A1/en not_active Withdrawn
- 2015-11-16 KR KR1020177016253A patent/KR20170096112A/ko not_active Withdrawn
- 2015-11-16 CA CA2967368A patent/CA2967368A1/en not_active Abandoned
- 2015-11-16 WO PCT/US2015/060941 patent/WO2016081384A1/en not_active Ceased
- 2015-11-16 BR BR112017010198A patent/BR112017010198A2/pt not_active IP Right Cessation
- 2015-11-16 SG SG10201807625PA patent/SG10201807625PA/en unknown
- 2015-11-16 CN CN201580061883.XA patent/CN106999583A/zh active Pending
- 2015-11-16 SG SG11201703605QA patent/SG11201703605QA/en unknown
- 2015-11-16 JP JP2017526558A patent/JP2017537090A/ja active Pending
- 2015-11-16 US US14/942,896 patent/US20160166685A1/en not_active Abandoned
- 2015-11-16 AU AU2015350242A patent/AU2015350242A1/en not_active Abandoned
- 2015-11-16 RU RU2017121096A patent/RU2017121096A/ru unknown
- 2015-11-16 MX MX2017006320A patent/MX2017006320A/es unknown
-
2017
- 2017-05-11 IL IL252251A patent/IL252251A0/en unknown
- 2017-06-16 US US15/625,572 patent/US20170290913A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015350242A1 (en) | 2017-06-29 |
| SG10201807625PA (en) | 2018-10-30 |
| WO2016081384A1 (en) | 2016-05-26 |
| EP3221360A1 (en) | 2017-09-27 |
| US20160166685A1 (en) | 2016-06-16 |
| CN106999583A (zh) | 2017-08-01 |
| CA2967368A1 (en) | 2016-05-26 |
| US20170290913A1 (en) | 2017-10-12 |
| BR112017010198A2 (pt) | 2017-12-26 |
| RU2017121096A3 (OSRAM) | 2019-10-17 |
| JP2017537090A (ja) | 2017-12-14 |
| SG11201703605QA (en) | 2017-06-29 |
| MX2017006320A (es) | 2017-08-10 |
| IL252251A0 (en) | 2017-07-31 |
| KR20170096112A (ko) | 2017-08-23 |
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