RU2015107740A - Способ измерения, реагент для измерения и набор для измерения pivka-ii - Google Patents
Способ измерения, реагент для измерения и набор для измерения pivka-ii Download PDFInfo
- Publication number
- RU2015107740A RU2015107740A RU2015107740A RU2015107740A RU2015107740A RU 2015107740 A RU2015107740 A RU 2015107740A RU 2015107740 A RU2015107740 A RU 2015107740A RU 2015107740 A RU2015107740 A RU 2015107740A RU 2015107740 A RU2015107740 A RU 2015107740A
- Authority
- RU
- Russia
- Prior art keywords
- antibody
- pivka
- specified
- mixture
- binding fragment
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract 24
- 108010063628 acarboxyprothrombin Proteins 0.000 title claims abstract 14
- 239000003153 chemical reaction reagent Substances 0.000 title claims 3
- 238000005259 measurement Methods 0.000 title 3
- 239000012634 fragment Substances 0.000 claims abstract 14
- 239000000203 mixture Substances 0.000 claims abstract 12
- 239000000427 antigen Substances 0.000 claims abstract 11
- 102000036639 antigens Human genes 0.000 claims abstract 11
- 108091007433 antigens Proteins 0.000 claims abstract 11
- 238000003018 immunoassay Methods 0.000 claims abstract 7
- 210000002966 serum Anatomy 0.000 claims abstract 6
- 108010094028 Prothrombin Proteins 0.000 claims abstract 3
- 102100027378 Prothrombin Human genes 0.000 claims abstract 3
- 229940039716 prothrombin Drugs 0.000 claims abstract 3
- 108010041201 prothrombin fragment 1 Proteins 0.000 claims abstract 2
- 108010041206 prothrombin fragment 2 Proteins 0.000 claims 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012176761A JP6032470B2 (ja) | 2012-08-09 | 2012-08-09 | Ｐｉｖｋａ−ｉｉ測定方法、測定試薬及び測定キット |
| JP2012-176761 | 2012-08-09 | ||
| PCT/JP2013/071188 WO2014024853A1 (ja) | 2012-08-09 | 2013-08-06 | Pivka-ii測定方法、測定試薬及び測定キット |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2015107740A true RU2015107740A (ru) | 2016-09-27 |
Family
ID=50068077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015107740A RU2015107740A (ru) | 2012-08-09 | 2013-08-06 | Способ измерения, реагент для измерения и набор для измерения pivka-ii |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10539559B2 (enExample) |
| EP (1) | EP2884277B1 (enExample) |
| JP (1) | JP6032470B2 (enExample) |
| KR (1) | KR102100152B1 (enExample) |
| CN (1) | CN104520710B (enExample) |
| RU (1) | RU2015107740A (enExample) |
| TW (1) | TWI589876B (enExample) |
| WO (1) | WO2014024853A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104698174B (zh) * | 2015-02-28 | 2017-10-31 | 江苏宜偌维盛生物技术有限公司 | 一种胃蛋白酶原ⅰ和ⅱ联合检测试剂盒 |
| US10830771B2 (en) | 2015-10-07 | 2020-11-10 | Fujirebio Inc. | PIVKA-II assay method and method for manufacturing reagent or kit for PIVKA-II immunoassay |
| KR102696526B1 (ko) * | 2017-07-13 | 2024-08-19 | 에프. 호프만-라 로슈 아게 | Pivka에 대한 신규 결합제 및 어세이 |
| CN109207462B (zh) * | 2018-08-01 | 2021-05-11 | 深圳市新产业生物医学工程股份有限公司 | 异常凝血酶原及其制备方法和包含其的检测剂、试剂盒及应用 |
| CN112816694A (zh) * | 2020-12-31 | 2021-05-18 | 泰州泽成生物技术有限公司 | 一种异常凝血酶原检测试剂盒及制备方法 |
| CN115097122B (zh) * | 2022-06-15 | 2025-08-26 | 安徽惠邦生物工程有限公司 | 抗缪勒氏管激素抗体-酶标记物及其制备方法和应用 |
| CN120137043A (zh) * | 2023-12-13 | 2025-06-13 | 菲鹏生物股份有限公司 | 抗pivka-ii抗体及其用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6060557A (ja) | 1983-09-13 | 1985-04-08 | Eisai Co Ltd | Ｐｉｖｋａ−２の測定方法および試薬 |
| US5811310A (en) * | 1986-09-30 | 1998-09-22 | Albert Einstein College Of Medicine Of Yeshiva Univ. | The Alz-50 monoclonal antibody and diagnostic assay for alzheimer's disease |
| JP2702616B2 (ja) | 1991-03-12 | 1998-01-21 | エーザイ株式会社 | Ｐｉｖｋａ−ｉｉの測定試薬 |
| JP3307422B2 (ja) * | 1992-04-10 | 2002-07-24 | 株式会社ヤトロン | ヒトｐｉｖｋａ−ｉｉの免疫学的測定方法 |
| JPH0720127A (ja) * | 1993-05-07 | 1995-01-24 | Eisai Co Ltd | 各種ｐｉｖｋａの測定方法および測定試薬 |
| JP2867325B2 (ja) | 1995-08-03 | 1999-03-08 | 株式会社エスアールエル | 抗ｐｉｖｋａ−ｉｉ抗体産生ハイブリドーマ及び免疫学的測定方法 |
| JPH09249699A (ja) | 1996-03-11 | 1997-09-22 | Fujirebio Inc | 抗ヒトｐｉｖｋａ−ｉｉモノクローナル抗体、該抗体を産生するハイブリドーマ、該抗体を用いた測定試薬及び測定方法 |
| JP3316199B2 (ja) * | 1998-12-14 | 2002-08-19 | 三光純薬株式会社 | Ｐｉｖｋａ−ｉｉの免疫学的測定法 |
| JP2000346841A (ja) | 1999-06-09 | 2000-12-15 | Daiichi Radioisotope Labs Ltd | Ｐｉｖｋａ−ｉｉの測定方法 |
| DE60026023T2 (de) * | 1999-12-14 | 2006-07-27 | Sanko Junyaku Co., Ltd. | Verfahren zum immunologischen bestimmen von pivka-ii |
| US6448086B1 (en) * | 2000-01-18 | 2002-09-10 | Diagnostic Systems Laboratories, Inc. | Insulin-like growth factor system and cancer |
| DE10354403A1 (de) * | 2003-11-20 | 2005-06-23 | Dade Behring Marburg Gmbh | Gegen das Prothrombin-Fragment F 1+2 gerichtete Antikörper, ihre Herstellung und Verwendung |
| JP2007192557A (ja) * | 2006-01-17 | 2007-08-02 | Perseus Proteomics Inc | Ｃ型肝炎患者の肝疾患の重篤化をモニターする方法および肝癌の診断方法 |
| CN101377505A (zh) * | 2008-04-16 | 2009-03-04 | 北京科美东雅生物技术有限公司 | 脱γ羧基凝血酶原微孔板化学发光免疫分析测定试剂盒及其制备方法 |
| DE102008049601A1 (de) * | 2008-09-30 | 2010-04-01 | Siemens Healthcare Diagnostics Products Gmbh | Antikörper zur Bestimmung des Prothrombin-Fragments F2/F1+2 in einem homogenen Immunoassay |
-
2012
- 2012-08-09 JP JP2012176761A patent/JP6032470B2/ja active Active
-
2013
- 2013-08-06 KR KR1020157001025A patent/KR102100152B1/ko active Active
- 2013-08-06 US US14/420,122 patent/US10539559B2/en active Active
- 2013-08-06 WO PCT/JP2013/071188 patent/WO2014024853A1/ja not_active Ceased
- 2013-08-06 EP EP13828411.2A patent/EP2884277B1/en active Active
- 2013-08-06 CN CN201380042250.5A patent/CN104520710B/zh active Active
- 2013-08-06 RU RU2015107740A patent/RU2015107740A/ru not_active Application Discontinuation
- 2013-08-09 TW TW102128608A patent/TWI589876B/zh active
-
2019
- 2019-11-26 US US16/696,803 patent/US20200088722A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014024853A1 (ja) | 2014-02-13 |
| EP2884277A1 (en) | 2015-06-17 |
| US10539559B2 (en) | 2020-01-21 |
| KR102100152B1 (ko) | 2020-04-13 |
| KR20150041620A (ko) | 2015-04-16 |
| JP2014035278A (ja) | 2014-02-24 |
| CN104520710B (zh) | 2016-10-12 |
| TW201411128A (zh) | 2014-03-16 |
| US20200088722A1 (en) | 2020-03-19 |
| JP6032470B2 (ja) | 2016-11-30 |
| EP2884277B1 (en) | 2018-10-10 |
| EP2884277A4 (en) | 2016-04-27 |
| TWI589876B (zh) | 2017-07-01 |
| US20150219638A1 (en) | 2015-08-06 |
| CN104520710A (zh) | 2015-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20180213 |