RU2014113641A - Сконструированные ткани для применения в исследованиях in vitro, их массивы и способы их изготовления - Google Patents
Сконструированные ткани для применения в исследованиях in vitro, их массивы и способы их изготовления Download PDFInfo
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- RU2014113641A RU2014113641A RU2014113641/10A RU2014113641A RU2014113641A RU 2014113641 A RU2014113641 A RU 2014113641A RU 2014113641/10 A RU2014113641/10 A RU 2014113641/10A RU 2014113641 A RU2014113641 A RU 2014113641A RU 2014113641 A RU2014113641 A RU 2014113641A
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- 239000004744 fabric Substances 0.000 title claims abstract 21
- 238000000338 in vitro Methods 0.000 title claims abstract 5
- 238000000034 method Methods 0.000 title claims 13
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000853 adhesive Substances 0.000 claims abstract 13
- 230000001070 adhesive effect Effects 0.000 claims abstract 13
- 230000002792 vascular Effects 0.000 claims abstract 6
- -1 antibody Substances 0.000 claims abstract 4
- 239000003102 growth factor Substances 0.000 claims abstract 4
- 239000000017 hydrogel Substances 0.000 claims abstract 4
- 239000012528 membrane Substances 0.000 claims abstract 4
- 108090000623 proteins and genes Proteins 0.000 claims abstract 4
- 102000004169 proteins and genes Human genes 0.000 claims abstract 4
- 239000000126 substance Substances 0.000 claims abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract 3
- 230000001464 adherent effect Effects 0.000 claims abstract 2
- 210000001519 tissue Anatomy 0.000 claims 65
- 210000004027 cell Anatomy 0.000 claims 29
- 230000015572 biosynthetic process Effects 0.000 claims 4
- 210000000481 breast Anatomy 0.000 claims 3
- 238000003255 drug test Methods 0.000 claims 3
- 230000002124 endocrine Effects 0.000 claims 3
- 238000000099 in vitro assay Methods 0.000 claims 3
- 210000004379 membrane Anatomy 0.000 claims 3
- 210000000577 adipose tissue Anatomy 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000000988 bone and bone Anatomy 0.000 claims 2
- 210000001185 bone marrow Anatomy 0.000 claims 2
- 210000002808 connective tissue Anatomy 0.000 claims 2
- 210000002950 fibroblast Anatomy 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 210000002216 heart Anatomy 0.000 claims 2
- 238000011534 incubation Methods 0.000 claims 2
- 210000003734 kidney Anatomy 0.000 claims 2
- 210000004072 lung Anatomy 0.000 claims 2
- 210000002751 lymph Anatomy 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 210000000496 pancreas Anatomy 0.000 claims 2
- 210000003668 pericyte Anatomy 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 210000004994 reproductive system Anatomy 0.000 claims 2
- 210000004116 schwann cell Anatomy 0.000 claims 2
- 210000003491 skin Anatomy 0.000 claims 2
- 210000000130 stem cell Anatomy 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 210000003437 trachea Anatomy 0.000 claims 2
- 210000001789 adipocyte Anatomy 0.000 claims 1
- 210000002798 bone marrow cell Anatomy 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 210000000845 cartilage Anatomy 0.000 claims 1
- 210000003321 cartilage cell Anatomy 0.000 claims 1
- 210000001608 connective tissue cell Anatomy 0.000 claims 1
- 238000007877 drug screening Methods 0.000 claims 1
- 210000002889 endothelial cell Anatomy 0.000 claims 1
- 230000003511 endothelial effect Effects 0.000 claims 1
- 210000002919 epithelial cell Anatomy 0.000 claims 1
- 210000000981 epithelium Anatomy 0.000 claims 1
- 210000003238 esophagus Anatomy 0.000 claims 1
- 230000002496 gastric effect Effects 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 210000002064 heart cell Anatomy 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 210000003292 kidney cell Anatomy 0.000 claims 1
- 210000004185 liver Anatomy 0.000 claims 1
- 210000005229 liver cell Anatomy 0.000 claims 1
- 210000005228 liver tissue Anatomy 0.000 claims 1
- 210000005265 lung cell Anatomy 0.000 claims 1
- 210000003563 lymphoid tissue Anatomy 0.000 claims 1
- 210000005033 mesothelial cell Anatomy 0.000 claims 1
- 210000004400 mucous membrane Anatomy 0.000 claims 1
- 210000003205 muscle Anatomy 0.000 claims 1
- 210000000944 nerve tissue Anatomy 0.000 claims 1
- 210000002569 neuron Anatomy 0.000 claims 1
- 210000002747 omentum Anatomy 0.000 claims 1
- 230000002611 ovarian Effects 0.000 claims 1
- 210000002307 prostate Anatomy 0.000 claims 1
- 210000002027 skeletal muscle Anatomy 0.000 claims 1
- 210000002363 skeletal muscle cell Anatomy 0.000 claims 1
- 210000004927 skin cell Anatomy 0.000 claims 1
- 210000002460 smooth muscle Anatomy 0.000 claims 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 claims 1
- 210000000952 spleen Anatomy 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
- 210000002536 stromal cell Anatomy 0.000 claims 1
- 210000005092 tracheal tissue Anatomy 0.000 claims 1
- 210000003932 urinary bladder Anatomy 0.000 claims 1
- 210000005167 vascular cell Anatomy 0.000 claims 1
- 238000010276 construction Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
- A61L27/3891—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types as distinct cell layers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
- C12N5/0691—Vascular smooth muscle cells; 3D culture thereof, e.g. models of blood vessels
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/27—Lung cells, respiratory tract cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/28—Vascular endothelial cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2513/00—3D culture
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Vascular Medicine (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161533761P | 2011-09-12 | 2011-09-12 | |
| US201161533757P | 2011-09-12 | 2011-09-12 | |
| US201161533753P | 2011-09-12 | 2011-09-12 | |
| US61/533,761 | 2011-09-12 | ||
| US61/533,757 | 2011-09-12 | ||
| US61/533,753 | 2011-09-12 | ||
| PCT/US2012/054923 WO2013040078A2 (en) | 2011-09-12 | 2012-09-12 | Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2014113641A true RU2014113641A (ru) | 2015-10-20 |
Family
ID=47883950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2014113641/10A RU2014113641A (ru) | 2011-09-12 | 2012-09-12 | Сконструированные ткани для применения в исследованиях in vitro, их массивы и способы их изготовления |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20130190210A1 (OSRAM) |
| EP (1) | EP2756073B1 (OSRAM) |
| JP (2) | JP2014531204A (OSRAM) |
| KR (1) | KR20140072883A (OSRAM) |
| CN (2) | CN108619572A (OSRAM) |
| AU (2) | AU2012308715A1 (OSRAM) |
| BR (1) | BR112014005746A2 (OSRAM) |
| CA (2) | CA2848043C (OSRAM) |
| DK (1) | DK2756073T3 (OSRAM) |
| HK (1) | HK1200483A1 (OSRAM) |
| IL (1) | IL231449A0 (OSRAM) |
| RU (1) | RU2014113641A (OSRAM) |
| WO (1) | WO2013040078A2 (OSRAM) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8241905B2 (en) | 2004-02-24 | 2012-08-14 | The Curators Of The University Of Missouri | Self-assembling cell aggregates and methods of making engineered tissue using the same |
| EP2069493B1 (en) * | 2006-11-10 | 2013-07-10 | Ondek Pty Ltd | Methods and devices for the delivery of peptides into the gastric mucosa |
| CA2729559C (en) | 2008-06-24 | 2017-01-03 | The Curators Of The University Of Missouri | Self-assembling multicellular bodies and methods of producing a three-dimensional biological structure using the same |
| WO2012054195A2 (en) | 2010-10-21 | 2012-04-26 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue |
| HK1200483A1 (en) * | 2011-09-12 | 2015-08-07 | 奥加诺沃公司 | Engineered tissues for in vitro research uses, arrays thereof, and methods of making the same |
| WO2013075248A1 (en) | 2011-11-23 | 2013-05-30 | The Governing Council Of The University Of Toronto | Devices and methods for producing planar polymeric materials using microfluidics |
| US9499779B2 (en) | 2012-04-20 | 2016-11-22 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking |
| US9442105B2 (en) * | 2013-03-15 | 2016-09-13 | Organovo, Inc. | Engineered liver tissues, arrays thereof, and methods of making the same |
| WO2014176697A1 (en) | 2013-04-30 | 2014-11-06 | Chen haotian | Microfluidic devices and methods for the extrusion of tubular structures |
| US10119107B2 (en) * | 2013-05-30 | 2018-11-06 | The University Of Akron | Automated cell and tissue bioprinter |
| EP3013380B1 (en) * | 2013-06-24 | 2022-11-23 | Ramot at Tel-Aviv University Ltd. | Omentum based scaffold and delivery system |
| WO2015017579A1 (en) | 2013-07-31 | 2015-02-05 | Organovo, Inc. | Automated devices, systems, and methods for the fabrication of tissue |
| EP3656557B1 (en) | 2013-10-11 | 2021-12-08 | Advanced Solutions Life Sciences, LLC | System and workstation for the design, fabrication and assembly of bio-material constructs |
| KR20160090828A (ko) * | 2013-11-05 | 2016-08-01 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 내장된 혈관구조를 가진 조직 구조물을 프린팅하는 방법 |
| MX2016006990A (es) * | 2013-11-30 | 2017-05-04 | Agency Science Tech & Res | Peptidos autoensamblables, peptidomimeticos y conjugados peptidicos como bloques de construccion para la biofabricacion e impresion. |
| WO2015129881A1 (ja) * | 2014-02-28 | 2015-09-03 | 国立大学法人大阪大学 | 細胞の立体構造体の製造方法 |
| KR20170013865A (ko) * | 2014-04-04 | 2017-02-07 | 오가노보, 인크. | 조작된 3차원 유방 조직, 지방조직, 및 종양 질병 모델 |
| GB201406716D0 (en) * | 2014-04-15 | 2014-05-28 | Insphero Ag | Method of preparing cells for 3D tissue culture |
| US20160040132A1 (en) * | 2014-08-06 | 2016-02-11 | Oregon Health & Science University | Three-dimensional bioprinted pancreatic tumor model |
| EA028039B1 (ru) * | 2014-09-05 | 2017-09-29 | Частное Учреждение Лаборатория Биотехнологических Исследований "3Д Биопринтинг Солюшенс" | Устройство и способы печати биологических тканей и органов |
| CN107106734A (zh) * | 2014-09-24 | 2017-08-29 | 加利福尼亚大学董事会 | 三维生物打印的人工角膜 |
| CN107002033B (zh) * | 2014-10-06 | 2021-08-10 | 奥加诺沃公司 | 工程化肾组织、其阵列及其制备方法 |
| JP2017537654A (ja) | 2014-11-05 | 2017-12-21 | オルガノボ インコーポレイテッド | 人工三次元皮膚組織、そのアレイ、およびその製造方法 |
| AU2014277667B2 (en) | 2014-12-15 | 2022-07-14 | The University Of Queensland | Differentiation of pluripotent stem cells to form renal organoids |
| KR102311639B1 (ko) * | 2015-03-26 | 2021-10-12 | 주식회사 티앤알바이오팹 | 심근조직 재생용 3차원 구조체의 제조방법 |
| EP3280463B1 (en) | 2015-04-07 | 2021-06-09 | Revotek Co., Ltd | Compositions for cell-based three dimensional printing |
| TWI741980B (zh) * | 2015-04-07 | 2021-10-11 | 大陸商四川藍光英諾生物科技股份有限公司 | 一種生物磚及其用途 |
| DK3310902T3 (da) * | 2015-06-16 | 2022-11-14 | Aspect Biosystems Ltd | Kontinuerligt, bioprintet flerlagsvævsstruktur |
| CN105056302B (zh) * | 2015-08-26 | 2017-12-26 | 上海市肺科医院 | 一种生物性复合人工气管的制备方法及其应用 |
| WO2017066507A1 (en) * | 2015-10-16 | 2017-04-20 | Wake Forest University Health Sciences | Multi-layer airway organoids and methods of making and using the same |
| JP6817619B2 (ja) * | 2015-10-27 | 2021-01-20 | 学校法人慶應義塾 | マイクロビーズの製造方法及び足場の製造方法 |
| WO2017083402A1 (en) | 2015-11-09 | 2017-05-18 | Organovo, Inc. | Improved methods for tissue fabrication |
| EP4059507B1 (en) | 2015-12-16 | 2024-06-05 | Ramot at Tel-Aviv University Ltd. | Particles comprising decellularized omentum |
| WO2017123722A1 (en) | 2016-01-12 | 2017-07-20 | Cleveland State University | 3d-printed miniature biological constructs |
| EP3455348A4 (en) * | 2016-05-11 | 2019-12-18 | The Regents of The University of Michigan | HIERARCHICALLY STRUCTURED PROTEIN MATERIALS FOR THREE-DIMENSIONAL (3D) CELLULAR SUPPORT SYSTEMS |
| US10738297B2 (en) | 2016-05-13 | 2020-08-11 | University Of Washington | 3D printable hydrogel materials |
| DE102016109067B4 (de) * | 2016-05-17 | 2018-07-19 | Leibniz-Institut Für Polymerforschung Dresden E.V. | Verfahren zur Bildung von Nierentubuli |
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| JP7300986B2 (ja) | 2016-11-10 | 2023-06-30 | オルガノボ インコーポレイテッド | 人工腸組織およびその使用 |
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| WO2018094194A1 (en) | 2016-11-17 | 2018-05-24 | Cleveland State University | Chip platforms for microarray 3d bioprinting |
| IL249977A0 (en) | 2017-01-08 | 2017-04-30 | Ramot At Tel-Aviv Univ Ltd | 3D models of crops, methods for their preparation and their uses |
| US12252712B2 (en) | 2017-04-03 | 2025-03-18 | Organovo, Inc. | Use of engineered liver tissue constructs for modeling liver disorders |
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| CA3157246A1 (en) | 2013-03-21 |
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| US20210123906A1 (en) | 2021-04-29 |
| HK1200483A1 (en) | 2015-08-07 |
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| CA2848043C (en) | 2022-07-12 |
| JP2018171065A (ja) | 2018-11-08 |
| CA2848043A1 (en) | 2013-03-21 |
| CN108619572A (zh) | 2018-10-09 |
| KR20140072883A (ko) | 2014-06-13 |
| US20130190210A1 (en) | 2013-07-25 |
| AU2012308715A1 (en) | 2014-04-24 |
| US20180313822A1 (en) | 2018-11-01 |
| WO2013040078A2 (en) | 2013-03-21 |
| EP2756073A2 (en) | 2014-07-23 |
| AU2016203930A1 (en) | 2016-09-08 |
| DK2756073T3 (da) | 2021-03-22 |
| EP2756073A4 (en) | 2015-05-06 |
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