RU2000129933A - Новые кодирующие нуклеотидные последовательности гена glk - Google Patents
Новые кодирующие нуклеотидные последовательности гена glk Download PDFInfo
- Publication number
- RU2000129933A RU2000129933A RU2000129933/13A RU2000129933A RU2000129933A RU 2000129933 A RU2000129933 A RU 2000129933A RU 2000129933/13 A RU2000129933/13 A RU 2000129933/13A RU 2000129933 A RU2000129933 A RU 2000129933A RU 2000129933 A RU2000129933 A RU 2000129933A
- Authority
- RU
- Russia
- Prior art keywords
- polynucleotide
- gene encoding
- same time
- sequence
- amino acid
- Prior art date
Links
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 101150042675 glk gene Proteins 0.000 title 1
- 238000000034 method Methods 0.000 claims 15
- 239000002157 polynucleotide Substances 0.000 claims 13
- 102000040430 polynucleotide Human genes 0.000 claims 13
- 108091033319 polynucleotide Proteins 0.000 claims 13
- 150000008575 L-amino acids Chemical class 0.000 claims 6
- 150000001413 amino acids Chemical group 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 3
- 229920001184 polypeptide Polymers 0.000 claims 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 241000894006 Bacteria Species 0.000 claims 2
- 108010021582 Glucokinase Proteins 0.000 claims 2
- 102000030595 Glucokinase Human genes 0.000 claims 2
- 239000004472 Lysine Substances 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 239000013598 vector Substances 0.000 claims 2
- 108091000044 4-hydroxy-tetrahydrodipicolinate synthase Proteins 0.000 claims 1
- 108010055400 Aspartate kinase Proteins 0.000 claims 1
- 241000186216 Corynebacterium Species 0.000 claims 1
- 108010081616 FAD-dependent malate dehydrogenase Proteins 0.000 claims 1
- 102100025591 Glycerate kinase Human genes 0.000 claims 1
- 235000019766 L-Lysine Nutrition 0.000 claims 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 108091000080 Phosphotransferase Proteins 0.000 claims 1
- 108010053763 Pyruvate Carboxylase Proteins 0.000 claims 1
- 102100039895 Pyruvate carboxylase, mitochondrial Human genes 0.000 claims 1
- 101150033985 TPI gene Proteins 0.000 claims 1
- 238000009825 accumulation Methods 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 230000006696 biosynthetic metabolic pathway Effects 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 101150011371 dapA gene Proteins 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 238000000855 fermentation Methods 0.000 claims 1
- 230000004151 fermentation Effects 0.000 claims 1
- 101150073818 gap gene Proteins 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 102000006602 glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 claims 1
- 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 claims 1
- 108010086476 glycerate kinase Proteins 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 101150035025 lysC gene Proteins 0.000 claims 1
- 101150044424 lysE gene Proteins 0.000 claims 1
- 235000018977 lysine Nutrition 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000037353 metabolic pathway Effects 0.000 claims 1
- 101150094267 mqo gene Proteins 0.000 claims 1
- 230000035772 mutation Effects 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 101150053253 pgi gene Proteins 0.000 claims 1
- 101150047627 pgk gene Proteins 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 229930029653 phosphoenolpyruvate Natural products 0.000 claims 1
- 102000020233 phosphotransferase Human genes 0.000 claims 1
- 239000013600 plasmid vector Substances 0.000 claims 1
- 230000010076 replication Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19958159A DE19958159A1 (de) | 1999-12-02 | 1999-12-02 | Neue für das glk-Gen codierende Nukleotidsequenzen |
| DE19958159.2 | 1999-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2000129933A true RU2000129933A (ru) | 2003-01-10 |
Family
ID=7931209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2000129933/13A RU2000129933A (ru) | 1999-12-02 | 2000-12-01 | Новые кодирующие нуклеотидные последовательности гена glk |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20020040129A1 (enExample) |
| EP (1) | EP1106694A1 (enExample) |
| JP (1) | JP2001204481A (enExample) |
| KR (1) | KR20010062078A (enExample) |
| CN (1) | CN1305000A (enExample) |
| AU (1) | AU7198800A (enExample) |
| BR (1) | BR0005678A (enExample) |
| CA (1) | CA2325227A1 (enExample) |
| DE (1) | DE19958159A1 (enExample) |
| HU (1) | HUP0004783A2 (enExample) |
| ID (1) | ID28565A (enExample) |
| MX (1) | MXPA00011815A (enExample) |
| PL (1) | PL344237A1 (enExample) |
| RU (1) | RU2000129933A (enExample) |
| SK (1) | SK17942000A3 (enExample) |
| ZA (1) | ZA200007078B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10032173A1 (de) | 2000-07-01 | 2002-01-17 | Degussa | Neue für das plsC-Gen kodierende Nukleotidsequenzen |
| KR100956369B1 (ko) * | 2001-11-19 | 2010-05-10 | 메디진 아게 | 바이러스성 피부 질환 및 종양 질환 치료용 약제 |
| DE10162730A1 (de) | 2001-12-20 | 2003-07-03 | Degussa | Allele des glk-Gens aus coryneformen Bakterien |
| US7915018B2 (en) | 2004-10-22 | 2011-03-29 | Ajinomoto Co., Inc. | Method for producing L-amino acids using bacteria of the Enterobacteriaceae family |
| KR20250139930A (ko) * | 2024-03-14 | 2025-09-24 | 대상 주식회사 | L-라이신 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 l-라이신의 생산 방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0655149B2 (ja) * | 1985-03-12 | 1994-07-27 | 協和醗酵工業株式会社 | Ｌ―リジンの製造法 |
| AU685054C (en) * | 1992-05-14 | 2003-02-27 | Baylor College Of Medicine | Mutated steroid hormone receptors, methods for their use and molecular switch for gene therapy |
| DE19644566A1 (de) * | 1996-10-26 | 1998-04-30 | Forschungszentrum Juelich Gmbh | Mikrobielle Herstellung von Substanzen aus dem aromatischen Stoffwechsel / I |
| DE19644567A1 (de) * | 1996-10-26 | 1998-04-30 | Forschungszentrum Juelich Gmbh | Mikrobielle Herstellung von Substanzen aus dem aromatischen Stoffwechsel / II |
| DE19818541C2 (de) * | 1998-04-24 | 2003-04-10 | Forschungszentrum Juelich Gmbh | Mikrobielle Herstellung von Substanzen aus dem aromatischen Stoffwechsel / III |
| DE19924365A1 (de) * | 1999-05-27 | 2000-11-30 | Degussa | Verfahren zur fermentativen Herstellung von L-Aminosäuren und für das accDA Gen codierende Nukleotidsequenzen |
| ES2178979T1 (es) * | 1999-06-25 | 2003-01-16 | Basf Ag | Genes de corynebacterium glutamicum que codifican proteinas implicadas en el metabolismo del carbono y la produccion de energia. |
| JP4623825B2 (ja) | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
-
1999
- 1999-12-02 DE DE19958159A patent/DE19958159A1/de not_active Withdrawn
-
2000
- 2000-11-24 ID IDP20001019D patent/ID28565A/id unknown
- 2000-11-24 EP EP00125716A patent/EP1106694A1/de not_active Withdrawn
- 2000-11-27 SK SK1794-2000A patent/SK17942000A3/sk unknown
- 2000-11-29 CA CA002325227A patent/CA2325227A1/en not_active Abandoned
- 2000-11-29 MX MXPA00011815A patent/MXPA00011815A/es unknown
- 2000-11-29 JP JP2000363632A patent/JP2001204481A/ja active Pending
- 2000-11-30 US US09/725,898 patent/US20020040129A1/en not_active Abandoned
- 2000-11-30 ZA ZA200007078A patent/ZA200007078B/xx unknown
- 2000-12-01 RU RU2000129933/13A patent/RU2000129933A/ru not_active Application Discontinuation
- 2000-12-01 HU HU0004783A patent/HUP0004783A2/hu unknown
- 2000-12-01 BR BR0005678-2A patent/BR0005678A/pt not_active IP Right Cessation
- 2000-12-01 PL PL00344237A patent/PL344237A1/xx not_active Application Discontinuation
- 2000-12-01 CN CN00134610A patent/CN1305000A/zh active Pending
- 2000-12-02 KR KR1020000072627A patent/KR20010062078A/ko not_active Withdrawn
- 2000-12-04 AU AU71988/00A patent/AU7198800A/en not_active Abandoned
-
2002
- 2002-07-18 US US10/197,541 patent/US6913910B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE19958159A1 (de) | 2001-06-07 |
| US6913910B2 (en) | 2005-07-05 |
| ID28565A (id) | 2001-06-07 |
| US20020040129A1 (en) | 2002-04-04 |
| PL344237A1 (en) | 2001-06-04 |
| BR0005678A (pt) | 2001-08-21 |
| CN1305000A (zh) | 2001-07-25 |
| HU0004783D0 (enExample) | 2001-02-28 |
| ZA200007078B (en) | 2001-06-06 |
| US20030022320A1 (en) | 2003-01-30 |
| JP2001204481A (ja) | 2001-07-31 |
| HUP0004783A2 (hu) | 2003-03-28 |
| CA2325227A1 (en) | 2001-06-02 |
| SK17942000A3 (sk) | 2001-10-08 |
| EP1106694A1 (de) | 2001-06-13 |
| AU7198800A (en) | 2001-06-07 |
| KR20010062078A (ko) | 2001-07-07 |
| MXPA00011815A (es) | 2002-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20050201 |