RS105704A - Kiseli preparati insulina sa poboljšanom stabilnošću - Google Patents
Kiseli preparati insulina sa poboljšanom stabilnošćuInfo
- Publication number
- RS105704A RS105704A YUP-1057/04A YUP105704A RS105704A RS 105704 A RS105704 A RS 105704A YU P105704 A YUP105704 A YU P105704A RS 105704 A RS105704 A RS 105704A
- Authority
- RS
- Serbia
- Prior art keywords
- combinations
- insulin
- improved stability
- insulin preparations
- acidic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Ovaj pronalazak se odnosi na farmaceutsku formulaciju koja sadrže neki polipeptid, koji je izabran iz grupe koja obuhvata insulin, neki metabolit insulina, neki analog insulina, neki derivat insulina ili njihove kombinacije; neki tenzid ili kombinacije više tenzida; po izboru neko sredstvo za konzerviranje ili kombinacije više sredstava za konzerviranje; i po izboru neko sredstvo za izotonizaciju, pufer ili druge pomoćne supstance ili njihove kombinacije, pri čemu takva farmaceutska formulacija ima pH-vrednost u kiseloj oblasti.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MEP-2008-287A ME00180B (me) | 2002-06-18 | 2003-06-05 | Kiseli preparati insulina sa poboljšanom stabilnošću |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10227232A DE10227232A1 (de) | 2002-06-18 | 2002-06-18 | Saure Insulinzubereitungen mit verbesserter Stabilität |
PCT/EP2003/005887 WO2003105888A1 (de) | 2002-06-18 | 2003-06-05 | Saure insulinzubereitungen mit verbesserter stabilität |
Publications (2)
Publication Number | Publication Date |
---|---|
RS105704A true RS105704A (sr) | 2007-02-05 |
RS52388B RS52388B (sr) | 2013-02-28 |
Family
ID=29723248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU105704A RS52388B (sr) | 2002-06-18 | 2003-06-05 | Kiseli preparati insulina sa poboljšanom stabilnošću |
Country Status (38)
Country | Link |
---|---|
US (4) | US20040048783A1 (sr) |
EP (2) | EP1517697B1 (sr) |
JP (2) | JP5237522B2 (sr) |
KR (1) | KR101040029B1 (sr) |
CN (2) | CN1662252A (sr) |
AR (1) | AR039688A1 (sr) |
AU (1) | AU2003238471B2 (sr) |
BR (1) | BRPI0311877B8 (sr) |
CA (1) | CA2490116C (sr) |
CR (1) | CR7614A (sr) |
CY (1) | CY1113537T1 (sr) |
DE (1) | DE10227232A1 (sr) |
DK (1) | DK1517697T3 (sr) |
EC (1) | ECSP045496A (sr) |
ES (2) | ES2817879T3 (sr) |
HN (1) | HN2003000184A (sr) |
HR (1) | HRP20041200B1 (sr) |
IL (1) | IL165788A (sr) |
MA (1) | MA27205A1 (sr) |
ME (1) | ME00180B (sr) |
MX (1) | MXPA04012233A (sr) |
MY (1) | MY142354A (sr) |
NO (1) | NO328567B1 (sr) |
NZ (1) | NZ537211A (sr) |
OA (1) | OA12870A (sr) |
PA (1) | PA8575701A1 (sr) |
PE (1) | PE20040560A1 (sr) |
PL (1) | PL208773B1 (sr) |
PT (2) | PT2305288T (sr) |
RS (1) | RS52388B (sr) |
RU (1) | RU2313362C2 (sr) |
SV (1) | SV2004001556A (sr) |
TN (1) | TNSN04249A1 (sr) |
TW (1) | TWI315201B (sr) |
UA (1) | UA79477C2 (sr) |
UY (1) | UY27854A1 (sr) |
WO (1) | WO2003105888A1 (sr) |
ZA (1) | ZA200409273B (sr) |
Families Citing this family (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10227232A1 (de) * | 2002-06-18 | 2004-01-15 | Aventis Pharma Deutschland Gmbh | Saure Insulinzubereitungen mit verbesserter Stabilität |
DE602005014962D1 (de) * | 2004-03-12 | 2009-07-30 | Biodel Inc | Insulinzusammensetzungen mit verbesserter wirkstoffabsorption |
EP1758540A4 (en) * | 2004-05-24 | 2007-06-20 | Wockhardt Ltd | PURIFICATION OF INSULIN-LIKE MATERIAL BY REVERSE-PHASE CHROMATOGRAPHY |
UA75030C2 (en) * | 2005-11-30 | 2006-03-15 | Viktor Oleksandrovych Bykov | Method for obtaining stable aqueous solutions of drugs |
WO2007135117A2 (en) * | 2006-05-24 | 2007-11-29 | Novo Nordisk A/S | Soluble, stable insulin-containing formulations |
DE102006031955A1 (de) | 2006-07-11 | 2008-01-17 | Sanofi-Aventis Deutschland Gmbh | Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende |
DE102006031962A1 (de) * | 2006-07-11 | 2008-01-17 | Sanofi-Aventis Deutschland Gmbh | Amidiertes Insulin Glargin |
US20100120660A1 (en) * | 2007-04-30 | 2010-05-13 | Per Balschmidt | Highly concentrated insulin solutions and compositions |
JP5352596B2 (ja) * | 2008-01-04 | 2013-11-27 | バイオデル, インコーポレイテッド | 組織グルコースレベルの関数としてのインスリン放出のためのインスリン製剤 |
BRPI0907371A2 (pt) | 2008-01-09 | 2015-11-24 | Sanofi Aventis Deutschland | derivados de insulina com um perfil de tempo-ação muito retardado |
NZ586589A (en) | 2008-01-09 | 2012-04-27 | Sanofi Aventis Deutschland | Novel insulin analogues having an extremely delayed time-action profile |
ES2550308T3 (es) * | 2008-08-29 | 2015-11-06 | Genzyme Corporation | Formulaciones peptídicas de liberación controlada |
WO2010028055A1 (en) * | 2008-09-02 | 2010-03-11 | Biodel, Inc. | Insulin with a basal release profile |
BR122013025625B1 (pt) | 2008-10-17 | 2021-08-03 | Sanofi-Aventis Deutschland Gmbh | Composição farmacêutica, seu uso e método de preparação da mesma, kit e dispositivo |
US9060927B2 (en) * | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
AU2010270325B2 (en) * | 2009-07-06 | 2014-06-19 | Sanofi-Aventis Deutschland Gmbh | Aqueous insulin preparations containing methionine |
ES2676373T3 (es) | 2009-11-13 | 2018-07-19 | Sanofi-Aventis Deutschland Gmbh | Composición farmacéutica que comprende un agonista de GLP-1, una insulina y metionina |
SI2498801T1 (en) | 2009-11-13 | 2018-06-29 | Sanofi-Aventis Deutschland Gmbh | A pharmaceutical composition containing desPro36Exendin-4 (1-39) -Lys6-NH2 and methionine |
TW201138808A (en) | 2010-05-03 | 2011-11-16 | Bristol Myers Squibb Co | Serum albumin binding molecules |
US8637458B2 (en) | 2010-05-12 | 2014-01-28 | Biodel Inc. | Insulin with a stable basal release profile |
AU2011202239C1 (en) * | 2010-05-19 | 2017-03-16 | Sanofi | Long-acting formulations of insulins |
WO2011156476A2 (en) * | 2010-06-08 | 2011-12-15 | Biodel Inc. | Insulin with a basal release profile |
RS55378B1 (sr) | 2010-08-30 | 2017-03-31 | Sanofi Aventis Deutschland | Upotreba ave0010 za proizvodnju leka za tretman diabetes mellitus tipa 2 |
CN102188367B (zh) * | 2011-01-05 | 2012-11-07 | 山东新时代药业有限公司 | 一种甘精胰岛素注射液及其制备方法 |
JP2014504597A (ja) | 2011-01-20 | 2014-02-24 | ジーランド ファーマ アクティーゼルスカブ | アシル化グルカゴン類似体とインスリン類似体の組合せ物 |
US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
EP2741765B9 (fr) * | 2011-08-10 | 2016-09-28 | Adocia | Solution injectable d'au moins une insuline basale |
US9408893B2 (en) | 2011-08-29 | 2016-08-09 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for use in glycemic control in diabetes type 2 patients |
TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
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2002
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