RS104504A - Novi trombomodulin fuzioni proteini koji ciljaju tkivni faktor kao aktikoagulanti - Google Patents

Novi trombomodulin fuzioni proteini koji ciljaju tkivni faktor kao aktikoagulanti

Info

Publication number
RS104504A
RS104504A YUP-1045/04A YUP104504A RS104504A RS 104504 A RS104504 A RS 104504A YU P104504 A YUP104504 A YU P104504A RS 104504 A RS104504 A RS 104504A
Authority
RS
Serbia
Prior art keywords
fusion protein
domain
protein
antibody
protein according
Prior art date
Application number
YUP-1045/04A
Other languages
English (en)
Serbian (sr)
Inventor
David Light
Kirk Mc Lean
Original Assignee
Schering Aktiengesellschaft,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29401364&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS104504(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Aktiengesellschaft, filed Critical Schering Aktiengesellschaft,
Publication of RS104504A publication Critical patent/RS104504A/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/7455—Thrombomodulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
YUP-1045/04A 2002-05-01 2003-04-30 Novi trombomodulin fuzioni proteini koji ciljaju tkivni faktor kao aktikoagulanti RS104504A (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37656602P 2002-05-01 2002-05-01
PCT/US2003/013522 WO2003092602A2 (en) 2002-05-01 2003-04-30 Novel tissue factor targeted thrombomodulin fusion proteins as anticoagulants

Publications (1)

Publication Number Publication Date
RS104504A true RS104504A (sr) 2007-02-05

Family

ID=29401364

Family Applications (2)

Application Number Title Priority Date Filing Date
YUP-1045/04A RS104504A (sr) 2002-05-01 2003-04-30 Novi trombomodulin fuzioni proteini koji ciljaju tkivni faktor kao aktikoagulanti
YU102404A RS102404A (sr) 2002-05-01 2003-04-30 Nova antitela koja ciljaju tkivni faktor kao antikoagulanti

Family Applications After (1)

Application Number Title Priority Date Filing Date
YU102404A RS102404A (sr) 2002-05-01 2003-04-30 Nova antitela koja ciljaju tkivni faktor kao antikoagulanti

Country Status (29)

Country Link
US (3) US7250168B2 (https=)
EP (2) EP1503785B1 (https=)
JP (2) JP4460443B2 (https=)
KR (2) KR101013697B1 (https=)
CN (2) CN100563709C (https=)
AR (1) AR039515A1 (https=)
AT (2) ATE427121T1 (https=)
AU (2) AU2003225255B2 (https=)
BR (2) BR0304659A (https=)
CA (2) CA2483910A1 (https=)
CR (1) CR7584A (https=)
DE (2) DE60326970D1 (https=)
DK (2) DK1503785T3 (https=)
EC (2) ECSP045468A (https=)
ES (2) ES2354419T3 (https=)
HK (1) HK1080372A1 (https=)
IL (3) IL164733A0 (https=)
MX (2) MXPA04010795A (https=)
NO (2) NO20035848L (https=)
NZ (2) NZ536243A (https=)
PE (1) PE20040597A1 (https=)
PL (2) PL210582B1 (https=)
PT (2) PT1503785E (https=)
RS (2) RS104504A (https=)
RU (2) RU2345789C2 (https=)
TW (1) TWI343388B (https=)
UA (2) UA85996C2 (https=)
WO (2) WO2003092602A2 (https=)
ZA (2) ZA200409692B (https=)

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TWI841554B (zh) 2018-03-21 2024-05-11 丹麥商珍美寶股份有限公司 以鉑為主之劑與抗組織因子抗體－藥物共軛物的組合治療癌症之方法
TW202506732A (zh) 2018-05-07 2025-02-16 丹麥商珍美寶股份有限公司 使用抗ｐｄ－１抗體與抗組織因子抗體－藥物共軛體之組合以治療癌症之方法
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TWI844571B (zh) 2018-10-30 2024-06-11 丹麥商珍美寶股份有限公司 使用抗血管內皮生長因子（ｖｅｇｆ）抗體與抗組織因子（ｔｆ）抗體－藥物共軛體之組合以治療癌症之方法
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Also Published As

Publication number Publication date
US7622457B2 (en) 2009-11-24
KR20050045945A (ko) 2005-05-17
JP4460443B2 (ja) 2010-05-12
BR0304659A (pt) 2004-09-21
MXPA04010851A (es) 2005-02-14
EP1549341A4 (en) 2006-10-18
JP4567437B2 (ja) 2010-10-20
NO20035848L (no) 2004-02-27
UA81114C2 (en) 2007-12-10
MXPA04010795A (es) 2005-03-07
CA2483910A1 (en) 2003-11-13
EP1503785A2 (en) 2005-02-09
EP1549341A2 (en) 2005-07-06
EP1549341B1 (en) 2009-04-01
WO2003092602A3 (en) 2004-08-26
ATE427121T1 (de) 2009-04-15
KR20050045944A (ko) 2005-05-17
WO2003093422A3 (en) 2004-07-15
PE20040597A1 (es) 2004-10-06
EP1503785A4 (en) 2007-02-14
RU2320366C2 (ru) 2008-03-27
KR101013697B1 (ko) 2011-02-10
RS102404A (sr) 2006-12-15
CN100412090C (zh) 2008-08-20
ATE484524T1 (de) 2010-10-15
DK1549341T3 (da) 2009-07-06
PL210582B1 (pl) 2012-02-29
BR0304660A (pt) 2005-06-07
CN1665534A (zh) 2005-09-07
JP2005532045A (ja) 2005-10-27
HK1080372A1 (zh) 2006-04-28
IL164733A0 (en) 2005-12-18
ES2323056T3 (es) 2009-07-06
PL373960A1 (en) 2005-09-19
TW200307043A (en) 2003-12-01
DE60326970D1 (de) 2009-05-14
NO20035849L (no) 2004-02-27
TWI343388B (en) 2011-06-11
PT1549341E (pt) 2009-05-29
ECSP045468A (es) 2005-01-28
RU2345789C2 (ru) 2009-02-10
US7250168B2 (en) 2007-07-31
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