RO85820B - Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxid - Google Patents

Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxid

Info

Publication number
RO85820B
RO85820B RO108877A RO10887781A RO85820B RO 85820 B RO85820 B RO 85820B RO 108877 A RO108877 A RO 108877A RO 10887781 A RO10887781 A RO 10887781A RO 85820 B RO85820 B RO 85820B
Authority
RO
Romania
Prior art keywords
formula
general formula
quinoxaline
compound
preparing methyl
Prior art date
Application number
RO108877A
Other languages
English (en)
Other versions
RO85820A (ro
Inventor
Pal Banko
Daniel Bozsing
Janos Gundel
Karoly Magyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of RO85820A publication Critical patent/RO85820A/ro
Publication of RO85820B publication Critical patent/RO85820B/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fodder In General (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Inventia se refera la un procedeu pentru prepararea unor compusi cu formula generala I: (vezi formula) în R1 reprezinta hidrogen sau o grupa alchil inferior, caracterizat prin aceea ca un compus cu formula generala II: (vezi formula) unde Hlg este halogen, iar R1 are semnificatiile de mai sus, reactioneaza cu ditiocarbamat de amoniu avînd formula III: (vezi formula) în mediu apos acid, la temperatura camerei, si, daca se doreste se scindeaza un amestec racemic în enantiomeri si/sau, daca se doreste, se transforma un compus cu formula generala I, cu caracter bazic, într-o sare de aditie cu acid, biologic acceptabila a acestuia.
RO108877A 1980-06-03 1981-06-02 Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxid RO85820B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU801386A HU184293B (en) 1980-06-03 1980-06-03 Process for preparing quinoxaline-1,4-dioxide derivatives

Publications (2)

Publication Number Publication Date
RO85820A RO85820A (ro) 1984-11-25
RO85820B true RO85820B (ro) 1984-11-30

Family

ID=10954225

Family Applications (4)

Application Number Title Priority Date Filing Date
RO108877A RO85820B (ro) 1980-06-03 1981-06-02 Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxid
RO81104477A RO82505A (ro) 1980-06-03 1981-06-02 Procedeu pentru prepararea unor derivati de chinoxalinil-1,4-dioxizi$procedeu pentru prepararea unor derivati de chinoxalinil-1,4-dioxizi
RO108878A RO85821B (ro) 1980-06-03 1981-06-02 Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxid
RO108876A RO85819B (ro) 1980-06-03 1981-06-02 Procedeu de preparare a unor derivati de metil-chinoxalin-1, 4-dioxid

Family Applications After (3)

Application Number Title Priority Date Filing Date
RO81104477A RO82505A (ro) 1980-06-03 1981-06-02 Procedeu pentru prepararea unor derivati de chinoxalinil-1,4-dioxizi$procedeu pentru prepararea unor derivati de chinoxalinil-1,4-dioxizi
RO108878A RO85821B (ro) 1980-06-03 1981-06-02 Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxid
RO108876A RO85819B (ro) 1980-06-03 1981-06-02 Procedeu de preparare a unor derivati de metil-chinoxalin-1, 4-dioxid

Country Status (35)

Country Link
US (1) US4373100A (ro)
JP (1) JPS5724370A (ro)
AR (3) AR229613A1 (ro)
AU (1) AU539507B2 (ro)
BE (1) BE889048A (ro)
BR (1) BR8103477A (ro)
CA (1) CA1177486A (ro)
CH (1) CH648303A5 (ro)
CS (1) CS258108B2 (ro)
DD (2) DD159333A5 (ro)
DE (1) DE3121978A1 (ro)
DK (1) DK151258C (ro)
ES (4) ES8300719A1 (ro)
FI (1) FI73419C (ro)
FR (1) FR2483416B1 (ro)
GB (1) GB2078216B (ro)
GR (1) GR75689B (ro)
HK (1) HK91284A (ro)
HU (1) HU184293B (ro)
IE (1) IE52088B1 (ro)
IL (1) IL63018A (ro)
IN (1) IN154091B (ro)
IT (1) IT1211055B (ro)
LU (1) LU83409A1 (ro)
NL (1) NL8102660A (ro)
NO (1) NO158502C (ro)
NZ (1) NZ197269A (ro)
PH (2) PH17078A (ro)
PL (5) PL130659B1 (ro)
PT (1) PT73121B (ro)
RO (4) RO85820B (ro)
SE (1) SE454511B (ro)
SU (7) SU1192622A3 (ro)
YU (4) YU48449B (ro)
ZW (1) ZW12681A1 (ro)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1194451B (it) * 1983-11-07 1988-09-22 Daniele Gatti Composti utili per combattere la dissenteria dei suini e come fattori di crescita,metodo per prepararli e composizioni che li contengono
CN102464642B (zh) * 2010-11-18 2014-04-23 谢联金 一种化合物及其制备方法及其作为饲料添加剂的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1494068A (fr) * 1964-08-31 1967-09-08 Pfizer & Co C Procédé pour la préparation de di-nu-oxydes de quinoxalines
US3926992A (en) * 1972-11-03 1975-12-16 Pfizer Aldol products of 2-quinoxalinecarboxaldehy-1,4-dioxides
CS195508B1 (en) * 1977-08-02 1980-02-29 Jaromir Hebky Cyanacetylhydrazones of 2-formylquinoxalin-1,4-dioxide
US4303657A (en) * 1979-05-21 1981-12-01 International Minerals & Chemical Corp. Nitrohydroxyalkyl-substituted quinoxaxiline dioxides and alkanoic acid esters thereof
US4224324A (en) * 1979-05-21 1980-09-23 International Minerals And Chemical Corporation Nitro-olefin-substituted quinoxaline dioxides
HU184772B (en) * 1980-05-23 1984-10-29 Egyt Gyogyszervegyeszeti Gyar Process for preparing quinoxaline-1,4-dioxide derivatives

Also Published As

Publication number Publication date
HU184293B (en) 1984-07-30
YU42851B (en) 1988-12-31
PL130659B1 (en) 1984-08-31
ES8303363A1 (es) 1983-03-01
PL132408B1 (en) 1985-02-28
DK151258C (da) 1988-05-02
DE3121978A1 (de) 1982-02-25
SU1186616A1 (ru) 1985-10-23
GB2078216A (en) 1982-01-06
ES502681A0 (es) 1982-11-16
FI73419C (fi) 1987-10-09
ES8300719A1 (es) 1982-11-16
RO85821A (ro) 1984-11-25
PL133906B1 (en) 1985-07-31
PH18535A (en) 1985-08-09
IT1211055B (it) 1989-09-29
SU1205765A3 (ru) 1986-01-15
GB2078216B (en) 1984-06-20
SU1396957A3 (ru) 1988-05-15
CH648303A5 (de) 1985-03-15
AU7125781A (en) 1981-12-10
PL130660B1 (en) 1984-08-31
NZ197269A (en) 1984-10-19
SE454511B (sv) 1988-05-09
DD159333A5 (de) 1983-03-02
ES512695A0 (es) 1983-04-01
RO85819B (ro) 1984-11-30
ES512696A0 (es) 1983-03-01
SU1169537A3 (ru) 1985-07-23
IN154091B (ro) 1984-09-15
NO158502B (no) 1988-06-13
BR8103477A (pt) 1982-02-24
DD202384A5 (de) 1983-09-14
ES8304953A1 (es) 1983-04-01
YU139381A (en) 1983-12-31
FI73419B (fi) 1987-06-30
NO811859L (no) 1981-12-04
PL238597A1 (en) 1983-04-11
ES8303362A1 (es) 1983-03-01
NL8102660A (nl) 1982-01-04
GR75689B (ro) 1984-08-02
AU539507B2 (en) 1984-10-04
SU1192622A3 (ru) 1985-11-15
NO158502C (no) 1988-09-21
US4373100A (en) 1983-02-08
FR2483416A1 (fr) 1981-12-04
SU1189346A3 (ru) 1985-10-30
ZW12681A1 (en) 1982-06-30
YU87383A (en) 1983-12-31
PT73121B (en) 1982-07-15
FR2483416B1 (fr) 1985-12-27
HK91284A (en) 1984-11-30
PL231451A1 (en) 1983-12-19
YU42852B (en) 1988-12-31
AR231140A1 (es) 1984-09-28
SE8103472L (sv) 1981-12-04
PL238599A1 (en) 1983-04-11
IE811214L (en) 1981-12-03
RO85819A (ro) 1984-11-25
BE889048A (fr) 1981-12-02
PL238598A1 (en) 1983-04-11
CS258108B2 (en) 1988-07-15
ES512697A0 (es) 1983-03-01
JPS5724370A (en) 1982-02-08
PH17078A (en) 1984-05-24
YU87483A (en) 1983-12-31
PL130661B1 (en) 1984-08-31
DE3121978C2 (ro) 1987-06-19
FI811704L (fi) 1981-12-04
IL63018A (en) 1986-01-31
DK241481A (da) 1981-12-04
YU42853B (en) 1988-12-31
RO82505B (ro) 1983-08-30
RO85821B (ro) 1984-11-30
YU87583A (en) 1983-12-31
DK151258B (da) 1987-11-16
IE52088B1 (en) 1987-06-10
AR229879A1 (es) 1983-12-30
AR229613A1 (es) 1983-09-30
CA1177486A (en) 1984-11-06
RO85820A (ro) 1984-11-25
IL63018A0 (en) 1981-09-13
YU48449B (sh) 1998-07-10
SU1176838A3 (ru) 1985-08-30
RO82505A (ro) 1983-09-26
PT73121A (pt) 1981-07-01
LU83409A1 (de) 1981-09-11
IT8122084A0 (it) 1981-06-02

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