RO84094B - Procedeu pentru prepararea unor derivati de dihidropiridina - Google Patents
Procedeu pentru prepararea unor derivati de dihidropiridinaInfo
- Publication number
- RO84094B RO84094B RO108554A RO10855482A RO84094B RO 84094 B RO84094 B RO 84094B RO 108554 A RO108554 A RO 108554A RO 10855482 A RO10855482 A RO 10855482A RO 84094 B RO84094 B RO 84094B
- Authority
- RO
- Romania
- Prior art keywords
- page
- formula
- description
- general formula
- dihydropyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Procedeul pentru prepararea unor derivati de dihidropiridina cu formula generala I (vezi formula în pag.1 a descrierii) în care R este metil sau etil, R1 si R2 sînt diferiti si unul reprezinta ciclopropil sau metoximetil, iar celalalt reprezinta metil sau etil, R3 reprezinta unul sau doi substituenti halogen în pozitiile 2 si/sau 3 ale ciclului fenil, iar A este propil, este caracterizat prin aceea ca un compus cu formula generala II (vezi formula în pag.1 a descrierii) în care R2, R3 si A au semnificatiile de mai sus, se trateaza cu un compus cu formula generala III (vezi formula în pag.1 a descrierii) în care R si R1 au semnificatiile de mai sus, în prezenta unui alcanol inferior ca solvent, la temperatura camerei, dupa care compusul cu formula I obtinut se transforma, daca se doreste, într-o sare acceptabila fiziologic si/sau se transforma într-un stereoizomer pur al acestuia.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8105230A SE8105230L (sv) | 1981-09-03 | 1981-09-03 | Nya dihydropyridiner |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO84094A RO84094A (ro) | 1984-05-12 |
| RO84094B true RO84094B (ro) | 1984-06-30 |
Family
ID=20344487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO108554A RO84094B (ro) | 1981-09-03 | 1982-09-02 | Procedeu pentru prepararea unor derivati de dihidropiridina |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS5852286A (ro) |
| AU (1) | AU8779982A (ro) |
| DD (1) | DD208614A5 (ro) |
| DK (1) | DK381682A (ro) |
| FI (1) | FI823033L (ro) |
| GR (1) | GR78053B (ro) |
| IL (1) | IL66145A0 (ro) |
| NO (1) | NO822506L (ro) |
| OA (1) | OA07203A (ro) |
| PT (1) | PT75502B (ro) |
| RO (1) | RO84094B (ro) |
| SE (1) | SE8105230L (ro) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR851819B (ro) * | 1984-08-17 | 1985-11-26 | Wyeth John & Brother Ltd |
-
1981
- 1981-09-03 SE SE8105230A patent/SE8105230L/xx not_active Application Discontinuation
-
1982
- 1982-06-28 IL IL66145A patent/IL66145A0/xx unknown
- 1982-07-20 NO NO822506A patent/NO822506L/no unknown
- 1982-08-26 DK DK381682A patent/DK381682A/da not_active Application Discontinuation
- 1982-08-27 AU AU87799/82A patent/AU8779982A/en not_active Abandoned
- 1982-09-02 RO RO108554A patent/RO84094B/ro unknown
- 1982-09-02 JP JP57151868A patent/JPS5852286A/ja active Pending
- 1982-09-02 PT PT75502A patent/PT75502B/pt unknown
- 1982-09-02 OA OA57795A patent/OA07203A/xx unknown
- 1982-09-02 GR GR69188A patent/GR78053B/el unknown
- 1982-09-02 FI FI823033A patent/FI823033L/fi not_active Application Discontinuation
- 1982-09-03 DD DD82243010A patent/DD208614A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU8779982A (en) | 1983-03-10 |
| GR78053B (ro) | 1984-09-26 |
| RO84094A (ro) | 1984-05-12 |
| PT75502A (en) | 1982-10-01 |
| IL66145A0 (en) | 1982-09-30 |
| DK381682A (da) | 1983-03-04 |
| FI823033L (fi) | 1983-03-04 |
| OA07203A (fr) | 1984-04-30 |
| PT75502B (en) | 1985-11-25 |
| DD208614A5 (de) | 1984-04-04 |
| SE8105230L (sv) | 1983-03-04 |
| JPS5852286A (ja) | 1983-03-28 |
| FI823033A0 (fi) | 1982-09-02 |
| NO822506L (no) | 1983-03-04 |
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