DK448684A - Alkyldiaminderivater og deres anvendelse som laegemidler - Google Patents
Alkyldiaminderivater og deres anvendelse som laegemidler Download PDFInfo
- Publication number
- DK448684A DK448684A DK448684A DK448684A DK448684A DK 448684 A DK448684 A DK 448684A DK 448684 A DK448684 A DK 448684A DK 448684 A DK448684 A DK 448684A DK 448684 A DK448684 A DK 448684A
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- formula
- substituted
- alkoxy
- halogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU19183 | 1983-01-21 | ||
HU83191A HU190704B (en) | 1983-01-21 | 1983-01-21 | Process for preparing n-up-1-acyl-n-up-2-alkyl-diamines |
HU38683 | 1983-02-04 | ||
HU38583 | 1983-02-04 | ||
HU38483A HU189224B (en) | 1983-02-04 | 1983-02-04 | Process for preparing derivatives of n,n'-diacyl-diamino-alkane |
HU38583A HU190706B (en) | 1983-02-04 | 1983-02-04 | Process for preparing new phthalimide derivatives |
HU38683A HU190707B (en) | 1983-02-04 | 1983-02-04 | Process for preparing new quinazolinone derivatives |
HU38483 | 1983-02-04 | ||
PCT/HU1984/000005 WO1984002907A1 (en) | 1983-01-21 | 1984-01-23 | New alkyl diamine derivatives |
HU8400005 | 1984-01-23 |
Publications (4)
Publication Number | Publication Date |
---|---|
DK448684D0 DK448684D0 (da) | 1984-09-20 |
DK448684A true DK448684A (da) | 1984-11-21 |
DK165975B DK165975B (da) | 1993-02-22 |
DK165975C DK165975C (da) | 1993-07-26 |
Family
ID=27451957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK448684A DK165975C (da) | 1983-01-21 | 1984-09-20 | 3-(substitueret amino)-carbonylderivater af 2,2,5,5-tetramethylpyrrolin eller -pyrrolidin og farmaceutisk acceptable salte deraf, fremgangsmaade til deres fremstilling, antiarrhytmisk farmaceutisk praeparat indeholdende dem og fremgangsmaade til praeparatets fremstilling |
Country Status (7)
Country | Link |
---|---|
US (4) | US4703056A (da) |
EP (1) | EP0134225B1 (da) |
JP (1) | JPH0615527B2 (da) |
DE (1) | DE3473442D1 (da) |
DK (1) | DK165975C (da) |
FI (1) | FI76070C (da) |
WO (1) | WO1984002907A1 (da) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984002907A1 (en) * | 1983-01-21 | 1984-08-02 | Alkaloida Vegyeszeti Gyar | New alkyl diamine derivatives |
US5177089A (en) * | 1988-06-01 | 1993-01-05 | Eisai Co., Ltd. | Butenoic or propenoic acid derivative |
FI892362A (fi) * | 1988-06-01 | 1989-12-02 | Eisai Co Ltd | Buten- eller propensyraderivat. |
HUP9700392A1 (hu) * | 1997-02-10 | 1999-09-28 | ICN Magyarország Részvénytársaság | Egy vagy két hatóanyagot tartalmazó kardioprotektív hatású gyógyszerkészítmények |
WO2014031784A1 (en) | 2012-08-23 | 2014-02-27 | Alios Biopharma, Inc. | Compounds for the treatment of paramoxyvirus viral infections |
AU2014308991B2 (en) * | 2013-08-21 | 2019-02-14 | Janssen Biopharma, Inc. | Antiviral compounds |
JP6299932B2 (ja) * | 2015-09-04 | 2018-03-28 | Dic株式会社 | 安定剤化合物、液晶組成物および表示素子 |
WO2017038617A1 (ja) | 2015-09-04 | 2017-03-09 | Dic株式会社 | 液晶組成物及びそれを使用した液晶表示素子 |
KR20200094734A (ko) | 2017-09-22 | 2020-08-07 | 주빌런트 에피파드 엘엘씨 | Pad 억제제로서의 헤테로사이클릭 화합물 |
MX2020003341A (es) | 2017-10-18 | 2020-09-17 | Jubilant Epipad LLC | Compuestos de imidazo-piridina como inhibidores de pad. |
JP7279057B6 (ja) | 2017-11-06 | 2024-02-15 | ジュビラント プローデル エルエルシー | Pd1/pd-l1活性化の阻害剤としてのピリミジン誘導体 |
EP3704120B1 (en) | 2017-11-24 | 2024-03-06 | Jubilant Episcribe LLC | Heterocyclic compounds as prmt5 inhibitors |
MX2020009517A (es) | 2018-03-13 | 2021-01-20 | Jubilant Prodel LLC | Compuestos biciclicos como inhibidores de la interaccion/activacio n de pdl/pd-l1. |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3020288A (en) * | 1962-02-06 | Hypotensive compounds | ||
DE109345C (da) * | ||||
DE109347C (da) * | ||||
DE109346C (da) * | ||||
GB190004799A (en) * | 1900-03-13 | 1900-05-19 | George William Johnson | The Manufacture of Para-amidophenyl Glyoxylic Acid, its Substitution Products and Homologues. |
US3502692A (en) * | 1962-06-13 | 1970-03-24 | American Cyanamid Co | Cyclic nitroxides and process for preparing same |
GB983134A (en) * | 1962-06-13 | 1965-02-10 | American Cyanamid Co | Cyclic nitroxides and process for preparing same |
US3250771A (en) * | 1962-12-17 | 1966-05-10 | Geigy Chem Corp | 5-monocarbocyclic aryl-n-lower alkyl-2-pyrrolidine carboxylic acid, esters, amides and derivatives thereof |
US3535334A (en) * | 1966-12-07 | 1970-10-20 | Sumitomo Chemical Co | 1-piperonoyl-3-indolyl aliphatic acid derivatives |
US3715354A (en) * | 1968-10-04 | 1973-02-06 | Endo Lab | Oxoisoindoles |
US3631706A (en) * | 1969-02-25 | 1972-01-04 | Western Electric Co | Methods of and apparatus for forming an article having a tubular portion |
US4002757A (en) * | 1974-12-26 | 1977-01-11 | A. H. Robins Company, Incorporated | N-(1-substituted-3-pyrrolidinyl)-4-quinolinecarboxamides |
US4111901A (en) * | 1977-06-06 | 1978-09-05 | Borg-Warner Corporation | Hindered five-membered nitrogen rings as polyolefin stabilizers |
IL57415A (en) * | 1978-05-30 | 1984-08-31 | Smith Kline French Lab | Nitropyrrole compounds,process for preparing them and pharmaceutical compositions containing them |
DE3119796A1 (de) * | 1981-05-19 | 1982-12-23 | Hoechst Ag, 6000 Frankfurt | Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung |
US4452989A (en) * | 1982-06-01 | 1984-06-05 | Charles Of The Ritz Group Ltd. | Substantive moisturizing derivatives of 2-pyrrolidone-5-carboxylic acid and compositions containing same |
DE3331874A1 (de) * | 1982-09-13 | 1984-04-05 | Sandoz-Patent-GmbH, 7850 Lörrach | Neue thiophenderivate |
US4643758A (en) * | 1982-09-30 | 1987-02-17 | Eli Lilly And Company | Herbicidal furyl-, thienyl- and pyrrolyl-2-pyrrolidinones |
HU189214B (en) * | 1983-01-20 | 1986-06-30 | Alkaloida Vegyeszeti Gyar,Hu | Process for preparing pyrroline and pyrrolidine carboxamide derivatives |
WO1984002907A1 (en) * | 1983-01-21 | 1984-08-02 | Alkaloida Vegyeszeti Gyar | New alkyl diamine derivatives |
JPH0699307B2 (ja) * | 1987-08-20 | 1994-12-07 | キッセイ薬品工業株式会社 | 抗痴呆剤 |
US4920224A (en) * | 1988-03-24 | 1990-04-24 | Pfizer Inc. | Quinazolin-4(3H)-one derivatives as anticoccidial agents |
-
1984
- 1984-01-23 WO PCT/HU1984/000005 patent/WO1984002907A1/en active IP Right Grant
- 1984-01-23 US US06/662,298 patent/US4703056A/en not_active Expired - Fee Related
- 1984-01-23 DE DE8484900530T patent/DE3473442D1/de not_active Expired
- 1984-01-23 EP EP84900530A patent/EP0134225B1/en not_active Expired
- 1984-01-23 JP JP59500633A patent/JPH0615527B2/ja not_active Expired - Lifetime
- 1984-09-20 DK DK448684A patent/DK165975C/da active
- 1984-09-21 FI FI843721A patent/FI76070C/fi not_active IP Right Cessation
-
1987
- 1987-10-16 US US07/109,819 patent/US4897413A/en not_active Expired - Fee Related
-
1989
- 1989-11-27 US US07/441,370 patent/US5028609A/en not_active Expired - Fee Related
-
1990
- 1990-10-31 US US07/607,165 patent/US5032600A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK448684D0 (da) | 1984-09-20 |
US5032600A (en) | 1991-07-16 |
FI76070B (fi) | 1988-05-31 |
DE3473442D1 (de) | 1988-09-22 |
FI843721A0 (fi) | 1984-09-21 |
US4897413A (en) | 1990-01-30 |
WO1984002907A1 (en) | 1984-08-02 |
JPS60500669A (ja) | 1985-05-09 |
DK165975C (da) | 1993-07-26 |
DK165975B (da) | 1993-02-22 |
EP0134225A1 (en) | 1985-03-20 |
US5028609A (en) | 1991-07-02 |
EP0134225B1 (en) | 1988-08-17 |
JPH0615527B2 (ja) | 1994-03-02 |
FI76070C (fi) | 1988-09-09 |
US4703056A (en) | 1987-10-27 |
FI843721L (fi) | 1984-09-21 |
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