SE416298B - Forfarande for framstellning av nya bensimidazolinon derivat - Google Patents

Forfarande for framstellning av nya bensimidazolinon derivat

Info

Publication number
SE416298B
SE416298B SE7507026A SE7507026A SE416298B SE 416298 B SE416298 B SE 416298B SE 7507026 A SE7507026 A SE 7507026A SE 7507026 A SE7507026 A SE 7507026A SE 416298 B SE416298 B SE 416298B
Authority
SE
Sweden
Prior art keywords
derivatives
bensimidazolinon
procedure
preparation
new
Prior art date
Application number
SE7507026A
Other languages
English (en)
Other versions
SE7507026L (sv
Inventor
P A J Janssen
Heertum A H M T Van
J Vandenberk
Der Aa M J M C Van
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SE7507026L publication Critical patent/SE7507026L/sv
Publication of SE416298B publication Critical patent/SE416298B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
    • G01N21/766Chemiluminescence; Bioluminescence of gases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/10Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using catalysis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/17Nitrogen containing
    • Y10T436/173845Amine and quaternary ammonium
    • Y10T436/175383Ammonia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/17Nitrogen containing
    • Y10T436/177692Oxides of nitrogen
    • Y10T436/178459Only nitrogen dioxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
SE7507026A 1974-06-21 1975-06-18 Forfarande for framstellning av nya bensimidazolinon derivat SE416298B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/481,594 US3989707A (en) 1974-06-21 1974-06-21 Benzimidazolinone derivatives

Publications (2)

Publication Number Publication Date
SE7507026L SE7507026L (sv) 1975-12-22
SE416298B true SE416298B (sv) 1980-12-15

Family

ID=23912586

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7507026A SE416298B (sv) 1974-06-21 1975-06-18 Forfarande for framstellning av nya bensimidazolinon derivat
SE7601636A SE415298B (sv) 1974-06-21 1976-02-13 Forfarande for bestemning av ammoniak i en gasblandning som innerhaller andelar av kveveoxid och kvevedioxid

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7601636A SE415298B (sv) 1974-06-21 1976-02-13 Forfarande for bestemning av ammoniak i en gasblandning som innerhaller andelar av kveveoxid och kvevedioxid

Country Status (25)

Country Link
US (1) US3989707A (sv)
JP (1) JPS5840553B2 (sv)
AT (1) AT345833B (sv)
AU (1) AU500910B2 (sv)
BE (1) BE830403A (sv)
CA (1) CA1053235A (sv)
CH (1) CH615173A5 (sv)
CS (1) CS190480B2 (sv)
DE (1) DE2527261C2 (sv)
DK (1) DK141751B (sv)
ES (1) ES438714A1 (sv)
FI (1) FI59589C (sv)
FR (1) FR2275210A1 (sv)
GB (1) GB1505173A (sv)
HU (1) HU170435B (sv)
IE (1) IE41383B1 (sv)
IL (1) IL47529A (sv)
NL (1) NL180587C (sv)
NO (1) NO142400C (sv)
PH (1) PH13604A (sv)
PL (1) PL98220B1 (sv)
SE (2) SE416298B (sv)
SU (1) SU585811A3 (sv)
YU (1) YU159475A (sv)
ZA (1) ZA753968B (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4066772A (en) * 1975-07-21 1978-01-03 Janssen Pharmaceutica N.V. 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds
NZ181256A (en) * 1975-07-21 1978-04-28 Janssen Pharmaceutica Nv 1-(w-benzazol-11-ylalkyl)-piperidine derivatives and pharmaceutical compositions containing certain of these derivatives
US4076821A (en) * 1976-02-27 1978-02-28 Yoshitomi Pharmaceutical Industries, Ltd. 4,4-Diphenylcycloalkylpiperidines and psychotropic compositions thereof
US4219559A (en) * 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
MA19091A1 (fr) * 1980-03-10 1981-10-01 Janssen Pharmaceutica Nv Nouveaux derives de i-(4-aryl-cyclohexyl)piperidine .
US4777265A (en) * 1986-03-11 1988-10-11 Basf Aktiengesellschaft Preparation of acrylates and methacrylates
DE4107857A1 (de) * 1991-03-12 1992-09-17 Thomae Gmbh Dr K Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
US6180649B1 (en) 1996-04-19 2001-01-30 Nerosearch A/S 1-(4-piperidyl)-benzimidazoles having neurotrophic activity
KR20010020172A (ko) 1997-05-30 2001-03-15 나가사까 겐지로 2-옥소이미다졸 유도체
AU1185300A (en) * 1998-11-20 2000-06-13 Banyu Pharmaceutical Co., Ltd. 2-oxoimidazole derivatives
CA2379554A1 (en) 1999-07-21 2001-01-25 Fujisawa Pharmaceuticals Co., Ltd. Benzimidazolone derivatives and their use as phosphodiesterase inhibitors
US7244744B2 (en) * 2001-11-01 2007-07-17 Icagen, Inc. Piperidines
DE602006019119D1 (de) * 2005-09-30 2011-02-03 Glaxo Group Ltd Verbindungen mit aktivität am m1-rezeptor und ihre verwendung in der medizin
EP1937670A1 (en) * 2005-09-30 2008-07-02 Glaxo Group Limited Benzimidazolones which have activity at m1 receptor
US8288412B2 (en) * 2005-09-30 2012-10-16 Glaxo Group Limited Compounds which have activity at M1 receptor and their uses in medicine
GB0605784D0 (en) * 2006-03-22 2006-05-03 Glaxo Group Ltd Compounds
EP1997381A1 (en) * 2007-06-01 2008-12-03 Commissariat à l'Energie Atomique Use of a compound having a monogalactosyldiacylglycerol synthase inhibitory activity as herbicide or algaecide, herbicide and algaecide compositions
GB0718415D0 (en) * 2007-09-20 2007-10-31 Glaxo Group Ltd Compounds
CA2770904A1 (en) * 2009-08-12 2011-02-17 Jimmy T. Liang Process for the preparation of cathepsin s inhibitors
EP4353713A1 (en) * 2021-06-07 2024-04-17 Kinki University T-type calcium channel blocker

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (sv) * 1962-06-13
US3161645A (en) * 1962-12-18 1964-12-15 Res Lab Dr C Janssen N V 1-(1-aroylpropyl-4-piperidyl)-2-benzimidazolinones and related compounds
BE659364A (sv) * 1964-02-05
US3799932A (en) * 1970-03-20 1974-03-26 Sumitomo Chemical Co Gamma-piperidinobutyrophenones
JPS5511671B2 (sv) * 1971-08-26 1980-03-26

Also Published As

Publication number Publication date
FI751462A (sv) 1975-12-22
IL47529A0 (en) 1975-08-31
NO751735L (sv) 1975-12-23
NL180587B (nl) 1986-10-16
SU585811A3 (ru) 1977-12-25
JPS5840553B2 (ja) 1983-09-06
AU8113875A (en) 1976-11-18
CA1053235A (en) 1979-04-24
SE415298B (sv) 1980-09-22
DK141751C (sv) 1980-11-03
FR2275210A1 (fr) 1976-01-16
DE2527261A1 (de) 1976-01-08
CS190480B2 (en) 1979-05-31
DK141751B (da) 1980-06-09
IE41383L (en) 1975-12-21
AU500910B2 (en) 1979-06-07
PL98220B1 (pl) 1978-04-29
SE7507026L (sv) 1975-12-22
ATA476175A (de) 1978-02-15
ZA753968B (en) 1977-01-26
FR2275210B1 (sv) 1978-12-22
DK281975A (sv) 1975-12-22
GB1505173A (en) 1978-03-30
DE2527261C2 (de) 1986-09-04
NL180587C (nl) 1987-03-16
NL7507368A (nl) 1975-12-23
YU159475A (en) 1982-02-28
FI59589C (fi) 1981-09-10
CH615173A5 (sv) 1980-01-15
FI59589B (fi) 1981-05-29
NO142400B (no) 1980-05-05
SE7601636L (sv) 1976-02-13
JPS5113780A (sv) 1976-02-03
US3989707A (en) 1976-11-02
NO142400C (no) 1980-08-13
IE41383B1 (en) 1979-12-19
AT345833B (de) 1978-10-10
IL47529A (en) 1978-10-31
PH13604A (en) 1980-08-05
HU170435B (sv) 1977-06-28
BE830403A (nl) 1975-12-19
ES438714A1 (es) 1977-07-01

Similar Documents

Publication Publication Date Title
SE416298B (sv) Forfarande for framstellning av nya bensimidazolinon derivat
SE7604052L (sv) Nya erytromycinderivat och forfarande for framstellning derav
SE403371B (sv) Forfarande for framstellning av vissa angivna (1-hydroximino-2,2-disubstituerad-5-indanyloxi)-lagalkylansyror
SE7608808L (sv) Forfarande for framstellning av nya derivat av tiazolo/3,4-b/isokinolin
SE416811B (sv) Analogiforfarande for framstellning av nya, antibakteriellt aktiva derivat av amidinopenicillansyra
SE7504842L (sv) Forfarande for framstellning av adeninderivat..
DK139580B (da) Analogifremgangsmåde til fremstilling af additionssalte af piperidylindolderivater.
SE405598B (sv) Forfarande for framstellning av nya terapeutiskt verksamma derivat av 4-(3-amino-2-hydroxi-propoxi)-indol
SE402009B (sv) Forfarande for framstellning av 9-desoxi-prosta-5,9,(10),13-triensyraderivat
SE7513640L (sv) Forfarande for framstellning av 6-metyl-8-(substituerade) metylerogoliner
SE7509764L (sv) Forfarande for framstellning av omega-nor-cykloalkyl-13,14-dehydro-prostaglandiner
SE425248B (sv) Forfarande for framstellning ac derivat av 4-tia-2,6-diaza(3.2.0)-2-hepten-oner
SE7508793L (sv) Antibiotiska derivat av xk-62-2 samt forfarande for framstellning derav
SE7507648L (sv) Forfarande for framstellning av basiskt substituerade derivat av 4-hydroxi-bensimidazol
NO142524C (no) Analogifremgangsmaate for fremstilling av farmakologisk aktive cykloheksylfenyl-derivater
SE424638B (sv) Analogiforfarande for framstellning av 5,7-dihydroxi-tetrahydroisokinolin derivat
SE404367B (sv) Forfarande for framstellning av derivat av homofolsyra
FI55037B (fi) Foerfarande foer framstaellning av d-homosteroider med endokrin verkan
DK138540B (da) Analogifremgangsmåde til fremstilling af benzhydryloxyalkylaminderivater eller farmaceutisk acceptable syreadditionssalte deraf.
SE7610968L (sv) Forfarande for framstellning av biologiskt aktiva di-karboxylsyraderivat
SE7504507L (sv) Forfarande for framstellning av 5-nitroimidazolderivat.
SE7600687L (sv) Forfarande for framstellning av n-tricykliska derivat av azetidin
SE7505066L (sv) Forfarande for framstellning av cefalsporinderivat.
SE7607753L (sv) Forfarnde for framstellning av derivat av alfafenylpropionsyra
SE416726B (sv) Forfarande for framstellning av nya dibensylglykolsyra derivat