RO85821B - Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxid - Google Patents
Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxidInfo
- Publication number
- RO85821B RO85821B RO108878A RO10887881A RO85821B RO 85821 B RO85821 B RO 85821B RO 108878 A RO108878 A RO 108878A RO 10887881 A RO10887881 A RO 10887881A RO 85821 B RO85821 B RO 85821B
- Authority
- RO
- Romania
- Prior art keywords
- general formula
- lower alkyl
- nitro
- group
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/06—Anabolic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fodder In General (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Inventia se refera la un procedeu pentru prepararea compusilor cu formula generala I: (vezi formula) în care R1 reprezinta hidrogen sau alchil inferior, R2 si R3 formeaza, împreuna, o legatura de valenta, Q reprezinta un atom de carbon sau de azot, A este hidrogen, hidroximetil, alchil inferior, fenilalchil inferior sau alcoxi-carbonil inferior este 0 sau 1, B reprezinta nitro, cian, halogen, fenil, piridil, chinolil substituit, eventual, cu halogen sau nitro, ori o grupa cu formula generala Ii: (vezi formula) în care R5 este hidrogen sau alchilcarbonil inferior si R4 reprezinta nitro, amino, trifluormetil, alchil inferior sau alcoxi inferior sau A si b formeaza, împreuna atomul de carbon adiacent de care sînt atasati, un radical tiazolidinil, imidazolidinil, pirimidinil sau oxazolil, cu conditia ca, daca Q reprezinta un atom de azot, n este 0 si R reprezinta o grupa cu formula generala II, precum si cu conditia ca, daca Q reprezinta un atom de carbon, B este diferit de un grup cu formula generala II. procedeul consta în aceea ca se deshidrateaza compusii cu formula generala III: (vezi formula) în care A, B, R si Q au semnificatiile de mai sus, în prezenta de acid trifluoracetic sau anhidra triflioracetica, în mediu de dimetilsulfoxid sau dimetilformamida la temperatura camerei.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU801386A HU184293B (en) | 1980-06-03 | 1980-06-03 | Process for preparing quinoxaline-1,4-dioxide derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO85821A RO85821A (ro) | 1984-11-25 |
| RO85821B true RO85821B (ro) | 1984-11-30 |
Family
ID=10954225
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO108878A RO85821B (ro) | 1980-06-03 | 1981-06-02 | Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxid |
| RO108876A RO85819B (ro) | 1980-06-03 | 1981-06-02 | Procedeu de preparare a unor derivati de metil-chinoxalin-1, 4-dioxid |
| RO108877A RO85820B (ro) | 1980-06-03 | 1981-06-02 | Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxid |
| RO81104477A RO82505A (ro) | 1980-06-03 | 1981-06-02 | Procedeu pentru prepararea unor derivati de chinoxalinil-1,4-dioxizi$procedeu pentru prepararea unor derivati de chinoxalinil-1,4-dioxizi |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO108876A RO85819B (ro) | 1980-06-03 | 1981-06-02 | Procedeu de preparare a unor derivati de metil-chinoxalin-1, 4-dioxid |
| RO108877A RO85820B (ro) | 1980-06-03 | 1981-06-02 | Procedeu pentru prepararea unor derivati de metil-chinoxalin-1, 4-dioxid |
| RO81104477A RO82505A (ro) | 1980-06-03 | 1981-06-02 | Procedeu pentru prepararea unor derivati de chinoxalinil-1,4-dioxizi$procedeu pentru prepararea unor derivati de chinoxalinil-1,4-dioxizi |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US4373100A (ro) |
| JP (1) | JPS5724370A (ro) |
| AR (3) | AR229879A1 (ro) |
| AU (1) | AU539507B2 (ro) |
| BE (1) | BE889048A (ro) |
| BR (1) | BR8103477A (ro) |
| CA (1) | CA1177486A (ro) |
| CH (1) | CH648303A5 (ro) |
| CS (1) | CS258108B2 (ro) |
| DD (2) | DD159333A5 (ro) |
| DE (1) | DE3121978A1 (ro) |
| DK (1) | DK151258C (ro) |
| ES (4) | ES8300719A1 (ro) |
| FI (1) | FI73419C (ro) |
| FR (1) | FR2483416B1 (ro) |
| GB (1) | GB2078216B (ro) |
| GR (1) | GR75689B (ro) |
| HK (1) | HK91284A (ro) |
| HU (1) | HU184293B (ro) |
| IE (1) | IE52088B1 (ro) |
| IL (1) | IL63018A (ro) |
| IN (1) | IN154091B (ro) |
| IT (1) | IT1211055B (ro) |
| LU (1) | LU83409A1 (ro) |
| NL (1) | NL8102660A (ro) |
| NO (1) | NO158502C (ro) |
| NZ (1) | NZ197269A (ro) |
| PH (2) | PH17078A (ro) |
| PL (5) | PL130661B1 (ro) |
| PT (1) | PT73121B (ro) |
| RO (4) | RO85821B (ro) |
| SE (1) | SE454511B (ro) |
| SU (7) | SU1192622A3 (ro) |
| YU (4) | YU48449B (ro) |
| ZW (1) | ZW12681A1 (ro) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1194451B (it) * | 1983-11-07 | 1988-09-22 | Daniele Gatti | Composti utili per combattere la dissenteria dei suini e come fattori di crescita,metodo per prepararli e composizioni che li contengono |
| CN102464642B (zh) * | 2010-11-18 | 2014-04-23 | 谢联金 | 一种化合物及其制备方法及其作为饲料添加剂的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1494068A (fr) * | 1964-08-31 | 1967-09-08 | Pfizer & Co C | Procédé pour la préparation de di-nu-oxydes de quinoxalines |
| US3926992A (en) * | 1972-11-03 | 1975-12-16 | Pfizer | Aldol products of 2-quinoxalinecarboxaldehy-1,4-dioxides |
| CS195508B1 (en) * | 1977-08-02 | 1980-02-29 | Jaromir Hebky | Cyanacetylhydrazones of 2-formylquinoxalin-1,4-dioxide |
| US4224324A (en) * | 1979-05-21 | 1980-09-23 | International Minerals And Chemical Corporation | Nitro-olefin-substituted quinoxaline dioxides |
| US4303657A (en) * | 1979-05-21 | 1981-12-01 | International Minerals & Chemical Corp. | Nitrohydroxyalkyl-substituted quinoxaxiline dioxides and alkanoic acid esters thereof |
| HU184772B (en) * | 1980-05-23 | 1984-10-29 | Egyt Gyogyszervegyeszeti Gyar | Process for preparing quinoxaline-1,4-dioxide derivatives |
-
1980
- 1980-06-03 HU HU801386A patent/HU184293B/hu not_active IP Right Cessation
-
1981
- 1981-05-27 IN IN564/CAL/81A patent/IN154091B/en unknown
- 1981-06-02 RO RO108878A patent/RO85821B/ro unknown
- 1981-06-02 PL PL1981238599A patent/PL130661B1/pl unknown
- 1981-06-02 ZW ZW126/81A patent/ZW12681A1/xx unknown
- 1981-06-02 DD DD81230505A patent/DD159333A5/de not_active IP Right Cessation
- 1981-06-02 BR BR8103477A patent/BR8103477A/pt unknown
- 1981-06-02 PL PL1981242731A patent/PL132408B1/pl unknown
- 1981-06-02 CA CA000378885A patent/CA1177486A/en not_active Expired
- 1981-06-02 RO RO108876A patent/RO85819B/ro unknown
- 1981-06-02 BE BE1/010241A patent/BE889048A/fr not_active IP Right Cessation
- 1981-06-02 NZ NZ197269A patent/NZ197269A/xx unknown
- 1981-06-02 US US06/269,720 patent/US4373100A/en not_active Expired - Lifetime
- 1981-06-02 NL NL8102660A patent/NL8102660A/nl not_active Application Discontinuation
- 1981-06-02 FI FI811704A patent/FI73419C/fi not_active IP Right Cessation
- 1981-06-02 ES ES502681A patent/ES8300719A1/es not_active Expired
- 1981-06-02 FR FR8110868A patent/FR2483416B1/fr not_active Expired
- 1981-06-02 GB GB8116802A patent/GB2078216B/en not_active Expired
- 1981-06-02 YU YU139381A patent/YU48449B/sh unknown
- 1981-06-02 IT IT8122084A patent/IT1211055B/it active
- 1981-06-02 PL PL1981238598A patent/PL130660B1/pl unknown
- 1981-06-02 RO RO108877A patent/RO85820B/ro unknown
- 1981-06-02 PL PL1981238597A patent/PL130659B1/pl unknown
- 1981-06-02 SE SE8103472A patent/SE454511B/sv not_active IP Right Cessation
- 1981-06-02 IL IL63018A patent/IL63018A/xx unknown
- 1981-06-02 CH CH3587/81A patent/CH648303A5/de not_active IP Right Cessation
- 1981-06-02 AU AU71257/81A patent/AU539507B2/en not_active Ceased
- 1981-06-02 CS CS814080A patent/CS258108B2/cs unknown
- 1981-06-02 IE IE1214/81A patent/IE52088B1/en unknown
- 1981-06-02 DK DK241481A patent/DK151258C/da not_active IP Right Cessation
- 1981-06-02 PL PL1981231451A patent/PL133906B1/pl unknown
- 1981-06-02 RO RO81104477A patent/RO82505A/ro unknown
- 1981-06-02 DD DD81241587A patent/DD202384A5/de unknown
- 1981-06-02 PT PT73121A patent/PT73121B/pt unknown
- 1981-06-02 NO NO811859A patent/NO158502C/no unknown
- 1981-06-02 PH PH25711A patent/PH17078A/en unknown
- 1981-06-02 LU LU83409A patent/LU83409A1/de unknown
- 1981-06-03 DE DE19813121978 patent/DE3121978A1/de active Granted
- 1981-06-03 JP JP8555581A patent/JPS5724370A/ja active Pending
- 1981-06-03 SU SU813294401A patent/SU1192622A3/ru active
- 1981-06-03 GR GR65142A patent/GR75689B/el unknown
-
1982
- 1982-03-22 PH PH27030A patent/PH18535A/en unknown
- 1982-05-31 ES ES512697A patent/ES512697A0/es active Granted
- 1982-05-31 ES ES512695A patent/ES8304953A1/es not_active Expired
- 1982-05-31 ES ES512696A patent/ES512696A0/es active Granted
- 1982-07-09 SU SU823461110A patent/SU1396957A3/ru active
- 1982-08-04 AR AR290225A patent/AR229879A1/es active
- 1982-08-04 AR AR290224A patent/AR229613A1/es active
- 1982-09-16 SU SU823491021A patent/SU1176838A3/ru active
- 1982-09-16 SU SU823490999A patent/SU1169537A3/ru active
- 1982-10-16 SU SU823491000A patent/SU1205765A3/ru active
- 1982-10-28 SU SU823506791A patent/SU1186616A1/ru active
-
1983
- 1983-04-18 YU YU875/83A patent/YU42853B/xx unknown
- 1983-04-18 YU YU873/83A patent/YU42851B/xx unknown
- 1983-04-18 YU YU874/83A patent/YU42852B/xx unknown
- 1983-06-24 SU SU833608870A patent/SU1189346A3/ru active
-
1984
- 1984-05-10 AR AR296612A patent/AR231140A1/es active
- 1984-11-22 HK HK912/84A patent/HK91284A/xx unknown
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