DK167782A - Fremgangsmaade til fremstilling af (2,6-dimethoxy-4-hydroxy-phenyl)-(3-piperidinopropyl)-keton og additionssalte deraf - Google Patents

Fremgangsmaade til fremstilling af (2,6-dimethoxy-4-hydroxy-phenyl)-(3-piperidinopropyl)-keton og additionssalte deraf Download PDF

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Publication number
DK167782A
DK167782A DK167782A DK167782A DK167782A DK 167782 A DK167782 A DK 167782A DK 167782 A DK167782 A DK 167782A DK 167782 A DK167782 A DK 167782A DK 167782 A DK167782 A DK 167782A
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DK
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Prior art keywords
dimethoxy
formula
piperidinopropyl
ketone
see diagramm
Prior art date
Application number
DK167782A
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English (en)
Other versions
DK156002B (da
DK156002C (da
Inventor
L Lafon
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of DK167782A publication Critical patent/DK167782A/da
Publication of DK156002B publication Critical patent/DK156002B/da
Application granted granted Critical
Publication of DK156002C publication Critical patent/DK156002C/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK167782A 1981-04-15 1982-04-14 Analogifremgangsmaade til fremstilling af (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-keton eller syreadditionssalte eller kvaternaere ammoniumsalte deraf DK156002C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8107597A FR2504136A1 (fr) 1981-04-15 1981-04-15 (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-cetone et ses sels d'addition, utilisation en therapeutique et procede de preparation
FR8107597 1981-04-15

Publications (3)

Publication Number Publication Date
DK167782A true DK167782A (da) 1982-10-16
DK156002B DK156002B (da) 1989-06-12
DK156002C DK156002C (da) 1989-11-06

Family

ID=9257449

Family Applications (1)

Application Number Title Priority Date Filing Date
DK167782A DK156002C (da) 1981-04-15 1982-04-14 Analogifremgangsmaade til fremstilling af (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-keton eller syreadditionssalte eller kvaternaere ammoniumsalte deraf

Country Status (10)

Country Link
EP (1) EP0063075B1 (da)
JP (1) JPS57181073A (da)
AT (1) ATE8258T1 (da)
CA (1) CA1183853A (da)
DE (1) DE3260320D1 (da)
DK (1) DK156002C (da)
ES (1) ES511431A0 (da)
FR (1) FR2504136A1 (da)
GR (1) GR75918B (da)
IE (1) IE52871B1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534912B1 (fr) * 1982-10-26 1985-06-28 Lafon Labor Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation
FR2597864B1 (fr) * 1986-04-28 1990-11-16 Lafon Labor Nouveaux derives de la n-((trimethoxy-2,4,6-benzoyl)-3 propyl) piperidine, leurs procedes de preparation et leur application en therapeutique
JP2569940Y2 (ja) * 1992-02-14 1998-04-28 株式会社ヨシコー 摩擦クラッチ
HUT74870A (en) * 1993-05-26 1997-02-28 Syntex Inc Process for producing 1-phenylalkanone 5-ht4 receptor ligands and pharmaceutical compositions containing them

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092133B1 (da) * 1970-05-06 1974-03-22 Orsymonde
FR2134218A1 (en) * 1971-04-27 1972-12-08 Penciolelli Madeleine Phloroglucinol aminoketones - vasodilators and antispasmodics
GB2004883B (en) * 1977-09-26 1982-03-17 Lafon Labor Phloroglucinol derivatives their method of preparation and their use as pharmaceuticals
FR2404003A1 (fr) * 1977-09-26 1979-04-20 Lafon Labor Nouveaux derives de phloroglucinol, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
ES8304105A1 (es) 1983-02-16
DK156002B (da) 1989-06-12
EP0063075B1 (fr) 1984-07-04
JPH039112B2 (da) 1991-02-07
GR75918B (da) 1984-08-02
ATE8258T1 (de) 1984-07-15
EP0063075A1 (fr) 1982-10-20
JPS57181073A (en) 1982-11-08
FR2504136A1 (fr) 1982-10-22
ES511431A0 (es) 1983-02-16
IE52871B1 (en) 1988-03-30
DK156002C (da) 1989-11-06
DE3260320D1 (en) 1984-08-09
CA1183853A (en) 1985-03-12
IE820742L (en) 1982-10-15
FR2504136B1 (da) 1984-02-10

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Legal Events

Date Code Title Description
PBP Patent lapsed
B1 Patent granted (law 1993)
PBP Patent lapsed