PT97963A - Processo melhorado para a preparacao do acido 4-amino-1-hidroxibutilideno-1,1-bifosfonico (abp) ou dos seus sais - Google Patents

Processo melhorado para a preparacao do acido 4-amino-1-hidroxibutilideno-1,1-bifosfonico (abp) ou dos seus sais

Info

Publication number
PT97963A
PT97963A PT97963A PT9796391A PT97963A PT 97963 A PT97963 A PT 97963A PT 97963 A PT97963 A PT 97963A PT 9796391 A PT9796391 A PT 9796391A PT 97963 A PT97963 A PT 97963A
Authority
PT
Portugal
Prior art keywords
acid
salts
amino
abp
preparation
Prior art date
Application number
PT97963A
Other languages
English (en)
Other versions
PT97963B (pt
Inventor
Gerard R Kieczykowski
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24157769&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT97963(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT97963A publication Critical patent/PT97963A/pt
Publication of PT97963B publication Critical patent/PT97963B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
PT97963A 1990-06-20 1991-06-14 Processo melhorado para a preparacao do acido 4-amino-1-hidroxibutilideno-1,1-bifosfonico (abp) ou dos seus sais PT97963B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/540,997 US5019651A (en) 1990-06-20 1990-06-20 Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof

Publications (2)

Publication Number Publication Date
PT97963A true PT97963A (pt) 1992-03-31
PT97963B PT97963B (pt) 1998-11-30

Family

ID=24157769

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97963A PT97963B (pt) 1990-06-20 1991-06-14 Processo melhorado para a preparacao do acido 4-amino-1-hidroxibutilideno-1,1-bifosfonico (abp) ou dos seus sais

Country Status (21)

Country Link
US (1) US5019651A (pt)
EP (1) EP0462663B1 (pt)
JP (1) JPH07119229B2 (pt)
KR (1) KR0173467B1 (pt)
AT (1) ATE128470T1 (pt)
AU (1) AU642264B2 (pt)
CA (1) CA2044923C (pt)
CY (1) CY1907A (pt)
DE (1) DE69113325T2 (pt)
DK (1) DK0462663T3 (pt)
ES (1) ES2079026T3 (pt)
FI (1) FI94347C (pt)
GR (1) GR3017544T3 (pt)
HK (1) HK64496A (pt)
IE (1) IE69171B1 (pt)
IL (1) IL98462A (pt)
LV (1) LV11471B (pt)
NO (1) NO180050C (pt)
NZ (1) NZ238493A (pt)
PT (1) PT97963B (pt)
ZA (1) ZA914708B (pt)

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Also Published As

Publication number Publication date
US5019651A (en) 1991-05-28
IL98462A (en) 1995-12-08
DE69113325D1 (de) 1995-11-02
AU7849891A (en) 1992-01-02
NO912395D0 (no) 1991-06-19
LV11471A (lv) 1996-08-20
CA2044923A1 (en) 1991-12-21
JPH07119229B2 (ja) 1995-12-20
FI913008A (fi) 1991-12-21
CA2044923C (en) 1996-06-18
CY1907A (en) 1991-06-14
FI913008A0 (fi) 1991-06-19
HK64496A (en) 1996-04-19
IL98462A0 (en) 1992-07-15
NO180050C (no) 1997-02-05
NO180050B (no) 1996-10-28
AU642264B2 (en) 1993-10-14
ZA914708B (en) 1992-03-25
LV11471B (en) 1996-12-20
EP0462663A1 (en) 1991-12-27
IE912112A1 (en) 1992-01-01
ES2079026T3 (es) 1996-01-01
NZ238493A (en) 1992-09-25
DK0462663T3 (da) 1996-01-29
IE69171B1 (en) 1996-08-07
PT97963B (pt) 1998-11-30
NO912395L (no) 1991-12-23
EP0462663B1 (en) 1995-09-27
DE69113325T2 (de) 1996-05-02
JPH05132492A (ja) 1993-05-28
ATE128470T1 (de) 1995-10-15
FI94347B (fi) 1995-05-15
KR0173467B1 (en) 1999-04-01
FI94347C (fi) 1995-08-25
GR3017544T3 (en) 1995-12-31

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