WO1995019341A3 - Process for making 5-nitrobarbituric acid and salts thereof - Google Patents

Process for making 5-nitrobarbituric acid and salts thereof Download PDF

Info

Publication number
WO1995019341A3
WO1995019341A3 PCT/US1995/000031 US9500031W WO9519341A3 WO 1995019341 A3 WO1995019341 A3 WO 1995019341A3 US 9500031 W US9500031 W US 9500031W WO 9519341 A3 WO9519341 A3 WO 9519341A3
Authority
WO
WIPO (PCT)
Prior art keywords
salts
nitrobarbituric acid
making
aryl
substituted
Prior art date
Application number
PCT/US1995/000031
Other languages
French (fr)
Other versions
WO1995019341A2 (en
Inventor
Robert B Wardle
Original Assignee
Thiokol Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/178,215 external-priority patent/US5472534A/en
Application filed by Thiokol Corp filed Critical Thiokol Corp
Priority to AU15569/95A priority Critical patent/AU1556995A/en
Publication of WO1995019341A2 publication Critical patent/WO1995019341A2/en
Publication of WO1995019341A3 publication Critical patent/WO1995019341A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for preparing salts of 5-nitrobarbituric acid involves allowing an in situ generated a compound represented by formula (I) wherein R1 and R2 are the same or different and are H, C1 to C8 alkyl or substituted C1 to C8 alkyl, aryl or substituted, aryl, to condense with urea to obtain a condensation product; and neutralizing the condensation product with at least one organic base and another cation source (MX) at a pH » 7 and recovering the resulting salt of 5-nitrobarbituric acid.
PCT/US1995/000031 1994-01-06 1995-01-04 Process for making 5-nitrobarbituric acid and salts thereof WO1995019341A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU15569/95A AU1556995A (en) 1994-01-06 1995-01-04 Process for making 5-nitrobarbituric acid and salts thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/178,215 US5472534A (en) 1994-01-06 1994-01-06 Gas generant composition containing non-metallic salts of 5-nitrobarbituric acid
US08/178,215 1994-01-06
US08/179,737 US5428165A (en) 1994-01-06 1994-01-10 Process for making 5-introbarbituric acid and salts thereof
US08/179,737 1994-01-10

Publications (2)

Publication Number Publication Date
WO1995019341A2 WO1995019341A2 (en) 1995-07-20
WO1995019341A3 true WO1995019341A3 (en) 1995-08-31

Family

ID=26874104

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/000031 WO1995019341A2 (en) 1994-01-06 1995-01-04 Process for making 5-nitrobarbituric acid and salts thereof

Country Status (2)

Country Link
AU (1) AU1556995A (en)
WO (1) WO1995019341A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101525290B (en) * 2009-04-28 2012-06-13 安徽金邦医药化工有限公司 Preparation method of diethyl malonate

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3719604A (en) * 1970-02-03 1973-03-06 Dynamit Nobel Ag Pressurizing-gas-producing charges containing an aminoguanidine tetrazole and an oxygen-liberating or gas-evolving additive
US4142029A (en) * 1976-07-16 1979-02-27 Ciba-Geigy Corporation Bis-tetrazoles as chemical blowing agents for foaming thermoplastic resins
US4608102A (en) * 1984-11-14 1986-08-26 Omark Industries, Inc. Primer composition
US4948439A (en) * 1988-12-02 1990-08-14 Automotive Systems Laboratory, Inc. Composition and process for inflating a safety crash bag
US5015309A (en) * 1989-05-04 1991-05-14 Morton International, Inc. Gas generant compositions containing salts of 5-nitrobarbituric acid, salts of nitroorotic acid, or 5-nitrouracil
US5035757A (en) * 1990-10-25 1991-07-30 Automotive Systems Laboratory, Inc. Azide-free gas generant composition with easily filterable combustion products
US5084118A (en) * 1990-10-23 1992-01-28 Automotive Systems Laboratory, Inc. Ignition composition for inflator gas generators
US5139588A (en) * 1990-10-23 1992-08-18 Automotive Systems Laboratory, Inc. Composition for controlling oxides of nitrogen
US5197758A (en) * 1991-10-09 1993-03-30 Morton International, Inc. Non-azide gas generant formulation, method, and apparatus

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3719604A (en) * 1970-02-03 1973-03-06 Dynamit Nobel Ag Pressurizing-gas-producing charges containing an aminoguanidine tetrazole and an oxygen-liberating or gas-evolving additive
US4142029A (en) * 1976-07-16 1979-02-27 Ciba-Geigy Corporation Bis-tetrazoles as chemical blowing agents for foaming thermoplastic resins
US4608102A (en) * 1984-11-14 1986-08-26 Omark Industries, Inc. Primer composition
US4948439A (en) * 1988-12-02 1990-08-14 Automotive Systems Laboratory, Inc. Composition and process for inflating a safety crash bag
US5015309A (en) * 1989-05-04 1991-05-14 Morton International, Inc. Gas generant compositions containing salts of 5-nitrobarbituric acid, salts of nitroorotic acid, or 5-nitrouracil
US5084118A (en) * 1990-10-23 1992-01-28 Automotive Systems Laboratory, Inc. Ignition composition for inflator gas generators
US5139588A (en) * 1990-10-23 1992-08-18 Automotive Systems Laboratory, Inc. Composition for controlling oxides of nitrogen
US5035757A (en) * 1990-10-25 1991-07-30 Automotive Systems Laboratory, Inc. Azide-free gas generant composition with easily filterable combustion products
US5197758A (en) * 1991-10-09 1993-03-30 Morton International, Inc. Non-azide gas generant formulation, method, and apparatus

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HARTMAN ET AL.: "Nitrobarbituric Acid", ORGANIC SYNTHESIS, vol. II, 1943, pages 440 - 441 *
NUTUI ET AL.: "New syntheses of dilituric acid", REV. ROUMAINE, CHIM., vol. 16, 1971, pages 919 - 923 *
REDEMANN ET AL.: "The diliturates (5-nitrobarbiturates) of some physiologically important bases", JOURNAL OF AMERICAN CHEMICAL SOCIETY, vol. 62, 1940, pages 590 - 593 *
VAN ALPHEN J.: "The nitration of 4-methoxy and 4-ethoxy benzophenone", RECVIEL TRAV. CHEM., vol. 8, 1930, PAY-BAS, pages 381 - 382 *

Also Published As

Publication number Publication date
WO1995019341A2 (en) 1995-07-20
AU1556995A (en) 1995-08-01

Similar Documents

Publication Publication Date Title
KR910000768A (en) Method for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
AU642264B2 (en) Improved process for preparing 4-amino-1-hydroxybutylidene-1, 1-bisphosphonic acid (ABP) or salts thereof
DE69327567T2 (en) Process for the preparation of alanylglutamine
DE69030758D1 (en) Process for reducing H2S in asphalt
DE59808194D1 (en) METHOD FOR PRODUCING TRIAZOLINTHION DERIVATIVES
ES2113975T3 (en) AZIDA OF TRI-ALQUIL SUPERIOR-TIN AND ITS USE.
ATE189890T1 (en) METHOD FOR PRODUCING 2-(UN)SUBSTITUTED 4-ALKYLIMIDAZOLES
DE69222012T2 (en) Process for the preparation of alpha-ketoamide derivatives
RU95112834A (en) Method for production of octa-2,7-diene-1-ol
WO1995019341A3 (en) Process for making 5-nitrobarbituric acid and salts thereof
NO955007L (en) thiol compounds
PT1213279E (en) PROCESS FOR THE PREPARATION OF VENLAFAXIN
DE69321749D1 (en) Process for the preparation of ceftriaxone
DE69503093D1 (en) Process for the production of guanides
BR9406352A (en) Process for the manufacture of aminomethanophosphonic acid
BR9603728A (en) Process for the production of a compound
PT924195E (en) PROCESS FOR THE PREPARATION OF AMINOCIANAETHAMIDE
HU913420D0 (en) Process for the production of aliphatic amide and its salts
EP0376215A3 (en) Alpha-keto acid/amino acid salt compounds and a process for their production
DK159432C (en) METHOD FOR PREPARING 4-AMINO-5-DIALCOXYMETHYLPYRIMIDINE DERIVATIVES
DK0473435T3 (en) Mono-N, N-dimethyl-4-aminopyridinium sn-glycerol-3-phosphate, preparation and use thereof for the preparation of phosphatidic acids
DE69012213T2 (en) Phenylacetic acid derivative.
TH12632A (en) Heterocyclic compounds
FI961749A0 (en) A process for preparing a methanediphosphonic acid compound
DE68906654D1 (en) METHOD FOR PRODUCING CONJUGATED SERVES.

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AM AT AU BB BG BR BY CA CH CN CZ DE DK EE ES FI GB GE HU JP KE KG KP KR KZ LK LR LT LU LV MD MG MN MW MX NL NO NZ PL PT RO RU SD SE SI SK TJ TT UA UZ VN

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): KE MW SD SZ AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

AK Designated states

Kind code of ref document: A3

Designated state(s): AM AT AU BB BG BR BY CA CH CN CZ DE DK EE ES FI GB GE HU JP KE KG KP KR KZ LK LR LT LU LV MD MG MN MW MX NL NO NZ PL PT RO RU SD SE SI SK TJ TT UA UZ VN

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): KE MW SD SZ AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

NENP Non-entry into the national phase

Ref country code: CA

122 Ep: pct application non-entry in european phase