ZA914708B - Improved process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid(abp)or salts thereof - Google Patents

Improved process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid(abp)or salts thereof

Info

Publication number
ZA914708B
ZA914708B ZA914708A ZA914708A ZA914708B ZA 914708 B ZA914708 B ZA 914708B ZA 914708 A ZA914708 A ZA 914708A ZA 914708 A ZA914708 A ZA 914708A ZA 914708 B ZA914708 B ZA 914708B
Authority
ZA
South Africa
Prior art keywords
hydroxybutylidene
salts
amino
abp
improved process
Prior art date
Application number
ZA914708A
Other languages
English (en)
Inventor
Gerard R Kieczykowski
R Kieczykowski Gerard
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24157769&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA914708(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA914708B publication Critical patent/ZA914708B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA914708A 1990-06-20 1991-06-19 Improved process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid(abp)or salts thereof ZA914708B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/540,997 US5019651A (en) 1990-06-20 1990-06-20 Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof

Publications (1)

Publication Number Publication Date
ZA914708B true ZA914708B (en) 1992-03-25

Family

ID=24157769

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA914708A ZA914708B (en) 1990-06-20 1991-06-19 Improved process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid(abp)or salts thereof

Country Status (21)

Country Link
US (1) US5019651A (xx)
EP (1) EP0462663B1 (xx)
JP (1) JPH07119229B2 (xx)
KR (1) KR0173467B1 (xx)
AT (1) ATE128470T1 (xx)
AU (1) AU642264B2 (xx)
CA (1) CA2044923C (xx)
CY (1) CY1907A (xx)
DE (1) DE69113325T2 (xx)
DK (1) DK0462663T3 (xx)
ES (1) ES2079026T3 (xx)
FI (1) FI94347C (xx)
GR (1) GR3017544T3 (xx)
HK (1) HK64496A (xx)
IE (1) IE69171B1 (xx)
IL (1) IL98462A (xx)
LV (1) LV11471B (xx)
NO (1) NO180050C (xx)
NZ (1) NZ238493A (xx)
PT (1) PT97963B (xx)
ZA (1) ZA914708B (xx)

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Also Published As

Publication number Publication date
NO180050B (no) 1996-10-28
AU642264B2 (en) 1993-10-14
NZ238493A (en) 1992-09-25
KR0173467B1 (en) 1999-04-01
IL98462A (en) 1995-12-08
JPH07119229B2 (ja) 1995-12-20
DE69113325T2 (de) 1996-05-02
FI913008A0 (fi) 1991-06-19
FI94347B (fi) 1995-05-15
LV11471A (lv) 1996-08-20
FI94347C (fi) 1995-08-25
EP0462663A1 (en) 1991-12-27
CA2044923C (en) 1996-06-18
NO912395L (no) 1991-12-23
HK64496A (en) 1996-04-19
IL98462A0 (en) 1992-07-15
IE912112A1 (en) 1992-01-01
CA2044923A1 (en) 1991-12-21
AU7849891A (en) 1992-01-02
NO180050C (no) 1997-02-05
FI913008A (fi) 1991-12-21
US5019651A (en) 1991-05-28
IE69171B1 (en) 1996-08-07
ATE128470T1 (de) 1995-10-15
PT97963A (pt) 1992-03-31
DE69113325D1 (de) 1995-11-02
PT97963B (pt) 1998-11-30
GR3017544T3 (en) 1995-12-31
LV11471B (en) 1996-12-20
EP0462663B1 (en) 1995-09-27
DK0462663T3 (da) 1996-01-29
CY1907A (en) 1991-06-14
NO912395D0 (no) 1991-06-19
ES2079026T3 (es) 1996-01-01
JPH05132492A (ja) 1993-05-28

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