PT94790A - Processo para a preparacao de derivados de ciclosporina - Google Patents

Processo para a preparacao de derivados de ciclosporina

Info

Publication number
PT94790A
PT94790A PT94790A PT9479090A PT94790A PT 94790 A PT94790 A PT 94790A PT 94790 A PT94790 A PT 94790A PT 9479090 A PT9479090 A PT 9479090A PT 94790 A PT94790 A PT 94790A
Authority
PT
Portugal
Prior art keywords
preparation
cyclosporine derivatives
ser
derivatives
ciclosporin
Prior art date
Application number
PT94790A
Other languages
English (en)
Other versions
PT94790B (pt
Inventor
Marcel Karl Eberle
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of PT94790A publication Critical patent/PT94790A/pt
Publication of PT94790B publication Critical patent/PT94790B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT94790A 1989-07-24 1990-07-23 Processo para a preparacao de derivados de ciclosporina PT94790B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898916901A GB8916901D0 (en) 1989-07-24 1989-07-24 Improvements in or relating to organic compounds

Publications (2)

Publication Number Publication Date
PT94790A true PT94790A (pt) 1991-03-20
PT94790B PT94790B (pt) 1997-04-30

Family

ID=10660543

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94790A PT94790B (pt) 1989-07-24 1990-07-23 Processo para a preparacao de derivados de ciclosporina

Country Status (23)

Country Link
EP (1) EP0414632B1 (pt)
JP (1) JPH0730113B2 (pt)
KR (1) KR100201174B1 (pt)
AT (1) ATE144536T1 (pt)
AU (1) AU631667B2 (pt)
CA (1) CA2021788C (pt)
CZ (1) CZ411691A3 (pt)
DE (1) DE69028967T2 (pt)
DK (1) DK0414632T3 (pt)
ES (1) ES2092500T3 (pt)
FI (1) FI94355C (pt)
GB (1) GB8916901D0 (pt)
GR (1) GR3021667T3 (pt)
HK (1) HK1004268A1 (pt)
HU (1) HU206127B (pt)
IE (1) IE902669A1 (pt)
IL (1) IL95154A (pt)
MY (1) MY105942A (pt)
NZ (1) NZ234613A (pt)
PT (1) PT94790B (pt)
SA (1) SA91110205B1 (pt)
SK (1) SK411691A3 (pt)
ZA (1) ZA905823B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9105705D0 (en) * 1991-03-18 1991-05-01 Sandoz Ltd Improvements in or relating to organic compounds
GB9204466D0 (en) * 1992-03-02 1992-04-15 Sandoz Ltd Improvements in or relating to organic compounds
US5482850A (en) * 1993-10-29 1996-01-09 New England Biolabs, Inc. Method for identifying anti-parasitic compounds
WO1997011092A1 (fr) * 1994-04-07 1997-03-27 Nippon Shinyaku Co., Ltd. Derives de phosphates de cyclosporine et composition medicinale
US7807211B2 (en) 1999-09-03 2010-10-05 Advanced Cardiovascular Systems, Inc. Thermal treatment of an implantable medical device
US20070032853A1 (en) 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
US6790228B2 (en) 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
KR100681670B1 (ko) * 2001-02-14 2007-02-09 주식회사 엘지생활건강 [감마 히드록시 엔- 메틸-엘-루신9]사이클로스포린 에이를유효성분으로 하는 모발 성장 촉진제
KR100465012B1 (ko) 2001-05-11 2005-01-13 주식회사 엘지생활건강 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
ATE425178T1 (de) 2001-10-19 2009-03-15 Isotechnika Inc Synthese von cyclosporinanalogen
KR100865211B1 (ko) * 2001-10-26 2008-10-23 주식회사 엘지생활건강 비면역 [감마 히드록시 엔-메틸 엘-루신4] 사이클로스포린 유도체를 유효성분으로 하는 항암 화학요법 기인 탈모증상 억제제
US6987090B2 (en) 2002-05-09 2006-01-17 Lg Household & Health Care Ltd. Use of 3-position cyclosporin derivatives for hair growth
KR100439467B1 (ko) * 2002-11-13 2004-07-09 주식회사 엘지생활건강 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
FR2873585B1 (fr) * 2004-07-27 2006-11-17 Aventis Pharma Sa Nouvelles formulations galeniques de principes actifs
US7576057B2 (en) 2006-11-20 2009-08-18 Scynexis, Inc. Cyclic peptides
ES2666191T3 (es) * 2011-11-15 2018-05-03 Allergan, Inc. Un proceso para la cristalización de la forma 2 de la ciclosporina A
WO2020037530A1 (en) 2018-08-22 2020-02-27 Waterstone Pharmaceuticals (Wuhan) Co., Ltd. Crystalline form of compound and uses thereof in medicine

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH614931A5 (pt) 1975-11-04 1979-12-28 Sandoz Ag
DE2819094A1 (de) 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
SE448386B (sv) 1978-10-18 1987-02-16 Sandoz Ag Nya cyklosporinderivat, forfarande for framstellning av dem samt farmaceutisk komposition innehallande dem
AU548156B2 (en) 1980-02-14 1985-11-28 Novartis Ag Cyclo sporin
US4396542A (en) 1980-02-14 1983-08-02 Sandoz Ltd. Method for the total synthesis of cyclosporins, novel cyclosporins and novel intermediates and methods for their production
DE3260468D1 (en) * 1981-01-09 1984-09-06 Sandoz Ag Novel cyclosporins
CH667274A5 (de) * 1984-03-23 1988-09-30 Sandoz Ag Cyclosporine, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
JPH074269B2 (ja) 1984-10-04 1995-01-25 サンド・アクチエンゲゼルシャフト シクロスポリン類に対するモノクロ−ナル抗体
US4798823A (en) 1987-06-03 1989-01-17 Merck & Co., Inc. New cyclosporin analogs with modified "C-9 amino acids"
ES2059558T3 (es) * 1987-06-17 1994-11-16 Sandoz Ag Ciclosporins y su uso como productos farmaceuticos.
GB2206119B (en) 1987-06-22 1990-10-31 Merck & Co Inc A new cyclosporin derivative with modified "8-amino acid"
GB8717300D0 (en) 1987-07-22 1987-08-26 Nat Res Dev Cyclosporins
GB8717299D0 (en) 1987-07-22 1987-08-26 Nat Res Dev Peptides
GB2207678A (en) 1987-08-03 1989-02-08 Merck & Co Inc Novel immunosuppressive fluorinated cyclosporin analogs
HU205010B (en) 1987-09-15 1992-03-30 Sandoz Ag Process for producing pharmaceutical compositions comprising compounds soluble up to 1 per cent and having medical activity
GB2222770B (en) 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins

Also Published As

Publication number Publication date
KR910002902A (ko) 1991-02-26
SK411691A3 (en) 1995-07-11
GB8916901D0 (en) 1989-09-06
CZ411691A3 (cs) 1998-06-17
IE902669A1 (en) 1991-02-27
HK1004268A1 (en) 1998-11-20
PT94790B (pt) 1997-04-30
CA2021788A1 (en) 1991-01-25
AU5972790A (en) 1991-01-24
DE69028967T2 (de) 1997-05-15
CA2021788C (en) 2001-02-13
HU904224D0 (en) 1990-12-28
GR3021667T3 (en) 1997-02-28
EP0414632A3 (en) 1991-09-11
ES2092500T3 (es) 1996-12-01
EP0414632B1 (en) 1996-10-23
HUT54714A (en) 1991-03-28
DK0414632T3 (da) 1996-11-25
EP0414632A2 (en) 1991-02-27
IL95154A0 (en) 1991-06-10
IL95154A (en) 1995-03-30
SA91110205B1 (ar) 2004-08-07
ZA905823B (en) 1992-03-25
MY105942A (en) 1995-02-28
HU206127B (en) 1992-08-28
JPH0730113B2 (ja) 1995-04-05
AU631667B2 (en) 1992-12-03
JPH03218396A (ja) 1991-09-25
FI903706A0 (fi) 1990-07-23
FI94355C (fi) 1995-08-25
KR100201174B1 (ko) 1999-06-15
FI94355B (fi) 1995-05-15
DE69028967D1 (de) 1996-11-28
NZ234613A (en) 1992-09-25
ATE144536T1 (de) 1996-11-15

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19901019

PC3A Transfer or assignment

Free format text: 980209 NOVARTIS AG CH

MM3A Annulment or lapse

Effective date: 20050722