PT900797E - Um derivado de 1-metilcarbapenem - Google Patents

Um derivado de 1-metilcarbapenem

Info

Publication number
PT900797E
PT900797E PT97919696T PT97919696T PT900797E PT 900797 E PT900797 E PT 900797E PT 97919696 T PT97919696 T PT 97919696T PT 97919696 T PT97919696 T PT 97919696T PT 900797 E PT900797 E PT 900797E
Authority
PT
Portugal
Prior art keywords
lower alkyl
alkyl group
hydrogen atom
group
derivative
Prior art date
Application number
PT97919696T
Other languages
English (en)
Inventor
Isao Kawamoto
Satoshi Ohya
Yasuo Shimoji
Katsuya Ishikawa
Munetsugu Morimoto
Katsuhiko Kojima
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of PT900797E publication Critical patent/PT900797E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
PT97919696T 1996-04-26 1997-04-25 Um derivado de 1-metilcarbapenem PT900797E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10736496 1996-04-26

Publications (1)

Publication Number Publication Date
PT900797E true PT900797E (pt) 2002-11-29

Family

ID=14457217

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97919696T PT900797E (pt) 1996-04-26 1997-04-25 Um derivado de 1-metilcarbapenem

Country Status (18)

Country Link
US (1) US5977097A (pt)
EP (1) EP0900797B1 (pt)
KR (1) KR20000064997A (pt)
CN (1) CN1093861C (pt)
AT (1) ATE222588T1 (pt)
AU (1) AU710881B2 (pt)
CA (1) CA2252723A1 (pt)
CZ (1) CZ342098A3 (pt)
DE (1) DE69714841T2 (pt)
DK (1) DK0900797T3 (pt)
ES (1) ES2180977T3 (pt)
HK (1) HK1018260A1 (pt)
HU (1) HUP9902149A3 (pt)
NO (1) NO312900B1 (pt)
NZ (1) NZ332453A (pt)
PT (1) PT900797E (pt)
RU (1) RU2162088C2 (pt)
WO (1) WO1997041123A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ324447A (en) * 1995-12-21 1999-08-30 Sankyo Co 1-methyl-carbapenem substituted by a 4-pyrrolidinylthio group and medicaments
WO2000034282A1 (fr) * 1998-12-07 2000-06-15 Sankyo Company, Limited Derives de 1-methylcarbapenem
JP2003502373A (ja) * 1999-06-23 2003-01-21 メルク エンド カムパニー インコーポレーテッド インテグリン受容体アンタゴニスト
BRPI0212411B8 (pt) * 2001-09-26 2021-07-27 Merck & Co Inc ' processos para reduzir os níveis de solventes orgânicos em um sólido de carbapenem, e para fabricar um hidrato cristalino'
JPWO2008026527A1 (ja) * 2006-08-28 2010-01-21 株式会社カネカ 3−シアノピロリジン誘導体およびその塩の製造方法
CN101357917B (zh) * 2007-06-22 2011-03-23 山东轩竹医药科技有限公司 含有甲酰肼基的碳青霉烯化合物
CN101367809B (zh) * 2007-06-28 2011-04-27 山东轩竹医药科技有限公司 含有巯基吡咯烷甲酰肼的培南衍生物
CN101362760B (zh) * 2007-08-07 2010-12-15 山东轩竹医药科技有限公司 1β-甲基碳代青霉烯化合物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
IE950607L (en) * 1988-04-01 1989-10-01 Sankyo Co 2-(heterocyclylthio) carbapenem derivatives, their¹preparation and their use as antibiotics
JP2752143B2 (ja) * 1988-04-01 1998-05-18 三共株式会社 カルバペネム誘導体
JPH023687A (ja) * 1988-06-22 1990-01-09 Sankyo Co Ltd 1−メチルカルバペネム誘導体
FI96863C (fi) * 1990-02-23 1996-09-10 Sankyo Co Menetelmä lääkeaineina käyttökelpoisten /2-(1-homopiperatsiinikarbonyyli)pyrrolidin-4-yylitio/-6-(1-hydroksietyyli)-1-karbapen-2-eemi-3-karboksylaattisuolojen valmistamiseksi
JPH04211083A (ja) * 1990-02-23 1992-08-03 Sankyo Co Ltd カルバペネム−3−カルボン酸誘導体
US5712267A (en) * 1991-06-04 1998-01-27 Sankyo Company,. Limited Carbapenem derivatives, their preparation and their use as antibiotics
RU2093514C1 (ru) * 1991-06-04 1997-10-20 Санкио Компани Лимитед Производные 1-метилкарбапенема и способ их получения
CZ290002B6 (cs) * 1992-03-11 2002-05-15 Sankyo Company Limited Antimikrobiální karbapenemové deriváty, způsob výroby a farmaceutický prostředek
JP3411589B2 (ja) * 1992-05-11 2003-06-03 第一製薬株式会社 カルバペネム誘導体
JP3344662B2 (ja) * 1992-09-14 2002-11-11 三共株式会社 カルバペネム−3−カルボン酸誘導体
JPH06199860A (ja) * 1992-09-16 1994-07-19 Sankyo Co Ltd カルバペネム誘導体
JPH07228570A (ja) * 1993-12-22 1995-08-29 Sankyo Co Ltd 4−メルカプトピロリジン誘導体
JP3199300B2 (ja) * 1994-05-09 2001-08-13 三共株式会社 1−メチルカルバペネム誘導体
JPH0848667A (ja) * 1994-06-03 1996-02-20 Sankyo Co Ltd 4−メルカプトピロリジン誘導体

Also Published As

Publication number Publication date
CA2252723A1 (en) 1997-11-06
DK0900797T3 (da) 2002-09-09
NO984948D0 (no) 1998-10-23
CZ342098A3 (cs) 1999-02-17
AU710881B2 (en) 1999-09-30
US5977097A (en) 1999-11-02
ATE222588T1 (de) 2002-09-15
EP0900797A1 (en) 1999-03-10
RU2162088C2 (ru) 2001-01-20
NO312900B1 (no) 2002-07-15
CN1223655A (zh) 1999-07-21
CN1093861C (zh) 2002-11-06
HUP9902149A3 (en) 2002-01-28
AU2407697A (en) 1997-11-19
HUP9902149A2 (hu) 1999-10-28
HK1018260A1 (en) 1999-12-17
KR20000064997A (ko) 2000-11-06
ES2180977T3 (es) 2003-02-16
EP0900797A4 (en) 2000-07-19
DE69714841T2 (de) 2003-05-28
EP0900797B1 (en) 2002-08-21
WO1997041123A1 (fr) 1997-11-06
NO984948L (no) 1998-12-21
DE69714841D1 (de) 2002-09-26
NZ332453A (en) 2000-09-29

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