DE69930383D1 - Naphthimidobenzamid-derivate - Google Patents

Naphthimidobenzamid-derivate

Info

Publication number
DE69930383D1
DE69930383D1 DE69930383T DE69930383T DE69930383D1 DE 69930383 D1 DE69930383 D1 DE 69930383D1 DE 69930383 T DE69930383 T DE 69930383T DE 69930383 T DE69930383 T DE 69930383T DE 69930383 D1 DE69930383 D1 DE 69930383D1
Authority
DE
Germany
Prior art keywords
hydrogen atom
different
same
independently represents
naphthimidobenzamid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69930383T
Other languages
English (en)
Other versions
DE69930383T2 (de
Inventor
Kazuharu Noguchi
Motoji Wakida
Kenji Suzuki
Yuji Yamada
Tetsuji Asao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of DE69930383D1 publication Critical patent/DE69930383D1/de
Application granted granted Critical
Publication of DE69930383T2 publication Critical patent/DE69930383T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
DE69930383T 1998-07-03 1999-07-02 Naphtalimidobenzamid-Derivate Expired - Fee Related DE69930383T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18907898 1998-07-03
JP18907898 1998-07-03
PCT/JP1999/003574 WO2000001672A1 (fr) 1998-07-03 1999-07-02 Derives de naphtalimidobenzamide

Publications (2)

Publication Number Publication Date
DE69930383D1 true DE69930383D1 (de) 2006-05-11
DE69930383T2 DE69930383T2 (de) 2006-10-05

Family

ID=16234950

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69930383T Expired - Fee Related DE69930383T2 (de) 1998-07-03 1999-07-02 Naphtalimidobenzamid-Derivate

Country Status (9)

Country Link
US (1) US6300331B1 (de)
EP (1) EP1020446B1 (de)
JP (1) JP3357662B2 (de)
KR (1) KR100364205B1 (de)
AT (1) ATE320417T1 (de)
AU (1) AU727591B2 (de)
CA (1) CA2300069C (de)
DE (1) DE69930383T2 (de)
WO (1) WO2000001672A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2268450C (en) * 1996-10-21 2008-08-05 Allelix Biopharmaceuticals, Inc. Neurotrophin antagonist compositions
US6468990B1 (en) * 1999-05-17 2002-10-22 Queen's University At Kingston Method of inhibiting binding of nerve growth factor to p75 NTR receptor
AU2005201951C1 (en) * 1999-05-17 2009-07-16 Queen's University Method of inhibiting neurotrophin-receptor binding
US6492380B1 (en) * 1999-05-17 2002-12-10 Queen's University At Kingston Method of inhibiting neurotrophin-receptor binding
KR20080058403A (ko) 2005-09-15 2008-06-25 페인셉터 파마 코포레이션 뉴로트로핀 매개 활성 조절 방법
EP2050747A1 (de) * 2007-10-12 2009-04-22 BioAlliance Pharma Harmol- bzw. Harmolderivat-Dimere und deren Verwendung
WO2009089537A2 (en) * 2008-01-11 2009-07-16 Northwestern University Anti-cancer compounds
US8288387B2 (en) * 2008-03-05 2012-10-16 Council Of Scientific & Industrial Research Napthalimide-benzimidazole hybrids as potential antitumor agents and process for the preparation thereof
JP5834390B2 (ja) * 2010-10-05 2015-12-24 東レ・ファインケミカル株式会社 ジアシル誘導体の製造方法
JP2012077045A (ja) * 2010-10-05 2012-04-19 Toray Fine Chemicals Co Ltd 高純度ジアシル誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0125439B1 (de) * 1983-04-01 1990-01-24 Warner-Lambert Company 3,6-Disubstituierte-1,8-Naphthalimide, Verfahren zu ihrer Herstellung und ihre Verwendung
DE3942280A1 (de) 1989-12-21 1991-06-27 Knoll Ag N-substituierte naphthalimide, ihre herstellung und verwendung
US5086059A (en) * 1990-06-07 1992-02-04 Du Pont Merck Pharmaceutical Company Bis-naphthalimides as anticancer agents
US5206249A (en) * 1991-03-27 1993-04-27 Du Pont Merck Pharmaceutical Company Bis-naphthalimides containing amino-acid derived linkers as anticancer agents
JPH07501822A (ja) * 1991-12-11 1995-02-23 デュポン・ファーマシュウティカルズ・カンパニー 抗癌剤として有用な高度に水溶性のビス−ナフタルイミド

Also Published As

Publication number Publication date
CA2300069A1 (en) 2000-01-13
JP3357662B2 (ja) 2002-12-16
AU727591B2 (en) 2000-12-14
ATE320417T1 (de) 2006-04-15
EP1020446B1 (de) 2006-03-15
KR20010023464A (ko) 2001-03-26
EP1020446A4 (de) 2001-11-07
KR100364205B1 (ko) 2002-12-11
AU4396399A (en) 2000-01-24
US6300331B1 (en) 2001-10-09
DE69930383T2 (de) 2006-10-05
EP1020446A1 (de) 2000-07-19
CA2300069C (en) 2006-01-17
WO2000001672A1 (fr) 2000-01-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee